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Aliases for RNU6-8 Gene

Subcategory (RNA class) for RNU6-8 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU6-8 Gene

  • RNA, U6 Small Nuclear 8 2 3 5
  • U6-8 3

External Ids for RNU6-8 Gene

ORGUL Members for RNU6-8 Gene

Previous GeneCards Identifiers for RNU6-8 Gene

  • GC00U922497
  • GC03M098524
  • GC14M032674
  • GC14M032676

Summaries for RNU6-8 Gene

GeneCards Summary for RNU6-8 Gene

RNU6-8 (RNA, U6 Small Nuclear 8) is an RNA Gene, and is affiliated with the snRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU6-8 Gene

Genomics for RNU6-8 Gene

Regulatory Elements for RNU6-8 Gene

Enhancers for RNU6-8 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F032229 1.2 FANTOM5 Ensembl ENCODE 12.4 -27.4 -27417 2.1 CTCF JUN CEBPB RAD21 YY1 JUND MAFF ATF3 STAT3 SMC3 RNU6-7 RNU6-8 LOC100533787
GH14F032082 1.2 Ensembl ENCODE 11.8 +119.8 119785 3.0 ELF3 FEZF1 THRB ZSCAN9 DNMT3B RARA SLC30A9 CREM MIXL1 THAP11 RNU6-7 RNU6-8 ARHGAP5-AS1 GC14P032154
GH14F032074 1.1 ENCODE 11.5 +126.1 126115 5.9 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ZNF263 RNU6-8 RNU6-7 RPL21P5 LOC101927124 ARHGAP5-AS1 GC14P032154
GH14F032101 1 Ensembl ENCODE 11.9 +100.9 100878 1.2 PKNOX1 MTA2 FEZF1 ZEB2 TBX21 ZNF843 EP300 OSR2 ZNF121 ZNF316 ARHGAP5 RNU6-7 RNU6-8 ARHGAP5-AS1 GC14P032154
GH14F032134 1 ENCODE 11.8 +68.4 68410 0.1 PKNOX1 ZNF133 FEZF1 GLI4 ZNF2 ZNF121 GLIS2 KLF7 FOS ZNF263 LOC100533787 ENSG00000257472 ENSG00000258196 ENSG00000257155 RNU6-7 RNU6-8 ARHGAP5 DTD2 GC14P032154 ARHGAP5-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU6-8 on UCSC Golden Path with GeneCards custom track

Promoters for RNU6-8 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000416086 769 3801 PKNOX1 MLX WRNIP1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for RNU6-8 Gene

Chromosome:
14
Start:
32,203,163 bp from pter
End:
32,203,269 bp from pter
Size:
107 bases
Orientation:
Minus strand

Genomic View for RNU6-8 Gene

Genes around RNU6-8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU6-8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU6-8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU6-8 Gene

Proteins for RNU6-8 Gene

Post-translational modifications for RNU6-8 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU6-8 Gene

Domains & Families for RNU6-8 Gene

Gene Families for RNU6-8 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU6-8: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU6-8 Gene

Function for RNU6-8 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU6-8 Gene

Localization for RNU6-8 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU6-8 Gene

Pathways & Interactions for RNU6-8 Gene

SuperPathways for RNU6-8 Gene

No Data Available

Interacting Proteins for RNU6-8 Gene

Gene Ontology (GO) - Biological Process for RNU6-8 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU6-8 Gene

Transcripts for RNU6-8 Gene

mRNA/cDNA for RNU6-8 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU6-8 Gene

No ASD Table

Relevant External Links for RNU6-8 Gene

GeneLoc Exon Structure for
RNU6-8
ECgene alternative splicing isoforms for
RNU6-8

Expression for RNU6-8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNU6-8 Gene

genes like me logo Genes that share expression patterns with RNU6-8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU6-8 Gene

Orthologs for RNU6-8 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU6-8 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia U6 35
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U6 35
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U6 35
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm26243 35
  • 100 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia U6 35
  • 100 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii U6 35
  • 96 (a)
OneToMany
Species where no ortholog for RNU6-8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNU6-8 Gene

ENSEMBL:
Gene Tree for RNU6-8 (if available)
TreeFam:
Gene Tree for RNU6-8 (if available)

Paralogs for RNU6-8 Gene

No data available for Paralogs for RNU6-8 Gene

Variants for RNU6-8 Gene

Sequence variations from dbSNP and Humsavar for RNU6-8 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10129345 -- 32,203,279(+) AGAAG(A/T)AGTCA upstream-variant-2KB
rs111563394 -- 32,203,431(+) TGACC(A/G)CCAGG upstream-variant-2KB
rs112050814 -- 32,204,335(+) TAATG(A/G)TTTTA upstream-variant-2KB
rs113156332 -- 32,203,533(+) AGGAC(A/C)CAGGC upstream-variant-2KB
rs11342365 -- 32,205,123(+) TCACG(-/T)TTTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU6-8 Gene

Variant ID Type Subtype PubMed ID
dgv134n111 CNV deletion 26073780
dgv135n111 CNV deletion 26073780
esv1002005 CNV deletion 20482838
esv1972594 CNV deletion 18987734
esv2523863 CNV deletion 19546169
esv2672070 CNV deletion 23128226
esv2733339 CNV deletion 23290073
esv2758743 CNV gain+loss 17122850
esv2758896 CNV gain+loss 17122850
esv2758920 CNV gain+loss 17122850
esv2759205 CNV gain 17122850
esv3259 CNV loss 18987735
esv3545926 CNV deletion 23714750
esv3574862 CNV loss 25503493
esv3574863 CNV loss 25503493
esv3584226 CNV gain 25503493
esv3643383 CNV gain 21293372
esv3643384 CNV loss 21293372
esv3643385 CNV gain 21293372
esv3890859 CNV loss 25118596
esv3891198 CNV gain 25118596
esv8509 CNV loss 19470904
esv996651 CNV deletion 20482838
nsv1041463 CNV gain 25217958
nsv1068280 CNV deletion 25765185
nsv1160555 CNV deletion 26073780
nsv1578 CNV insertion 18451855
nsv2385 CNV insertion 18451855
nsv3041 CNV insertion 18451855
nsv428427 CNV gain 18775914
nsv469845 CNV loss 16826518
nsv470101 CNV loss 18288195
nsv512148 CNV loss 21212237
nsv524931 CNV gain 19592680
nsv545381 CNV gain 21841781
nsv545382 CNV loss 21841781
nsv569803 CNV gain 21841781
nsv578188 CNV loss 21841781
nsv7462 OTHER inversion 18451855
nsv826912 CNV gain 20364138
nsv828360 CNV loss 20364138
nsv829809 CNV loss 17160897
nsv832764 CNV gain 17160897
nsv833704 CNV gain 17160897
nsv953938 CNV deletion 24416366
nsv956356 CNV deletion 24416366
nsv9662 CNV gain 18304495

Relevant External Links for RNU6-8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU6-8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU6-8 Gene

Disorders for RNU6-8 Gene

No disorders were found for RNU6-8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU6-8 Gene

Publications for RNU6-8 Gene

  1. Multiple, dispersed human U6 small nuclear RNA genes with varied transcriptional efficiencies. (PMID: 12711679) Domitrovich A.M. … Kunkel G.R. (Nucleic Acids Res. 2003) 2 3 64

Products for RNU6-8 Gene

Sources for RNU6-8 Gene

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