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Aliases for RNU6-456P Gene

Subcategory (RNA class) for RNU6-456P Gene

snRNA

Aliases for RNU6-456P Gene

  • RNA, U6 Small Nuclear 456, Pseudogene 2 3 5

External Ids for RNU6-456P Gene

ORGUL Members for RNU6-456P Gene

Previous GeneCards Identifiers for RNU6-456P Gene

  • GC05M133837
  • GC00U934590

Summaries for RNU6-456P Gene

GeneCards Summary for RNU6-456P Gene

RNU6-456P (RNA, U6 Small Nuclear 456, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU6-456P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U6_snRNA: U6 snRNA is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA.

  • U6 spliceosomal RNA: U6 snRNA is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA [2]. This model hits a large number of sequences in vertebrate genomes, which appear to be U6 derived pseudogenes or repeats. This family has a high significance threshold to minimise this problem, but many annotated pseudogenes remain.

View fRNAdb secondary structures for RNU6-456P

Additional gene information for RNU6-456P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU6-456P Gene

Genomics for RNU6-456P Gene

Regulatory Elements for RNU6-456P Gene

Enhancers for RNU6-456P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05H134435 1.8 VISTA Ensembl ENCODE dbSUPER 11 +62.7 62665 5 HDGF FOXA2 PKNOX1 ATF1 ARNT ARID4B SIN3A YY1 TCF12 GATA2 CDKN2AIPNL JADE2 ENSG00000248559 RNU6-456P SKP1 ENSG00000250994 LOC102546229
GH05H134521 1.4 ENCODE dbSUPER 12 -25.2 -25240 7 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZBTB7B DDX46 ENSG00000270892 ENSG00000271128 ENSG00000248753 LOC105379188 C5orf66 RNU6-456P RPS10P11 CDKN2AIPNL SEC24A
GH05H134410 1.4 FANTOM5 ENCODE 11.2 +85.5 85494 8 HDGF PKNOX1 FOXA2 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 DDX46 RNU6-456P JADE2 CATSPER3 CDKL3 C5orf66 SKP1 CDKN2AIPNL RPS10P11
GH05H134529 1 Ensembl ENCODE dbSUPER 11.5 -30.3 -30313 1 ZNF121 SCRT1 SCRT2 RPS10P11 CDKN2AIPNL RNU6-456P ENSG00000248559 GC05M134520 JADE2
GH05H134445 0.9 ENCODE dbSUPER 11.9 +53.6 53567 2 MAZ MAX EBF1 RAD21 ATF2 NFIL3 ZNF629 ATF7 CREM RPS10P11 CDKN2AIPNL RNU6-456P JADE2 ENSG00000248559 SKP1 ENSG00000250994 LOC102546229
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU6-456P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU6-456P Gene

Chromosome:
5
Start:
134,500,178 bp from pter
End:
134,500,284 bp from pter
Size:
107 bases
Orientation:
Minus strand

Genomic View for RNU6-456P Gene

Genes around RNU6-456P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU6-456P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU6-456P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU6-456P Gene

ORGUL Member Location for RNU6-456P Gene

ORGUL Member Location for RNU6-456P gene

Proteins for RNU6-456P Gene

Post-translational modifications for RNU6-456P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU6-456P Gene

Domains & Families for RNU6-456P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU6-456P Gene

Function for RNU6-456P Gene

Phenotypes From GWAS Catalog for RNU6-456P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU6-456P Gene

Localization for RNU6-456P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU6-456P Gene

Pathways & Interactions for RNU6-456P Gene

SuperPathways for RNU6-456P Gene

No Data Available

Interacting Proteins for RNU6-456P Gene

Gene Ontology (GO) - Biological Process for RNU6-456P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU6-456P Gene

Drugs & Compounds for RNU6-456P Gene

No Compound Related Data Available

Transcripts for RNU6-456P Gene

fRNAdb Secondary structures for RNU6-456P Gene

  • RF00026;U6;AADB02009496.1/117146-117252

mRNA/cDNA for RNU6-456P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU6-456P Gene

No ASD Table

Relevant External Links for RNU6-456P Gene

GeneLoc Exon Structure for
RNU6-456P
ECgene alternative splicing isoforms for
RNU6-456P

Expression for RNU6-456P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU6-456P Gene

genes like me logo Genes that share expression patterns with RNU6-456P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU6-456P Gene

Orthologs for RNU6-456P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU6-456P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U6 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U6 34
  • 86 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia U6 34
  • 81 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia U6 34
  • 76 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia U6 34
  • 75 (a)
OneToMany
Species where no ortholog for RNU6-456P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU6-456P Gene

ENSEMBL:
Gene Tree for RNU6-456P (if available)
TreeFam:
Gene Tree for RNU6-456P (if available)

Paralogs for RNU6-456P Gene

No data available for Paralogs for RNU6-456P Gene

Variants for RNU6-456P Gene

Relevant External Links for RNU6-456P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU6-456P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU6-456P Gene

Disorders for RNU6-456P Gene

No disorders were found for RNU6-456P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU6-456P Gene

Publications for RNU6-456P Gene

  1. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  2. Spliceosomal small nuclear RNAs of Tetrahymena thermophila and some possible snRNA-snRNA base-pairing interactions. (PMID: 1960724) Orum H … Engberg J (Journal of molecular biology 1991) 1
  3. The spliceosomal snRNAs of Caenorhabditis elegans. (PMID: 2339054) Thomas J … Blumenthal T (Nucleic acids research 1990) 1

Products for RNU6-456P Gene

Sources for RNU6-456P Gene

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