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Aliases for RNU6-1 Gene

Subcategory (RNA class) for RNU6-1 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU6-1 Gene

  • RNA, U6 Small Nuclear 1 2 3 5
  • RNA, U6A Small Nuclear 2 3
  • RNU6A 3
  • RNU6 3
  • U6-1 3
  • U6 3

External Ids for RNU6-1 Gene

Previous HGNC Symbols for RNU6-1 Gene

  • RNU6A

Previous GeneCards Identifiers for RNU6-1 Gene

  • GC15U900950
  • GC15M065922
  • GC15M068132
  • GC07M122819

Summaries for RNU6-1 Gene

GeneCards Summary for RNU6-1 Gene

RNU6-1 (RNA, U6 Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class. Diseases associated with RNU6-1 include poikiloderma with neutropenia. Among its related pathways are RNA transport and mRNA Splicing - Major Pathway.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU6-1 Gene

Genomics for RNU6-1 Gene

Regulatory Elements for RNU6-1 Gene

Promoters for RNU6-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RNU6-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU6-1 Gene

Chromosome:
15
Start:
67,839,939 bp from pter
End:
67,840,045 bp from pter
Size:
107 bases
Orientation:
Minus strand

Genomic View for RNU6-1 Gene

Genes around RNU6-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU6-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU6-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU6-1 Gene

Proteins for RNU6-1 Gene

Post-translational modifications for RNU6-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU6-1 Gene

Domains & Families for RNU6-1 Gene

Gene Families for RNU6-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU6-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU6-1 Gene

Function for RNU6-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU6-1 Gene

Localization for RNU6-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU6-1 Gene

Pathways & Interactions for RNU6-1 Gene

genes like me logo Genes that share pathways with RNU6-1: view

Pathways by source for RNU6-1 Gene

2 KEGG pathways for RNU6-1 Gene
1 Qiagen pathway for RNU6-1 Gene

Interacting Proteins for RNU6-1 Gene

Gene Ontology (GO) - Biological Process for RNU6-1 Gene

None

No data available for SIGNOR curated interactions for RNU6-1 Gene

Drugs & Compounds for RNU6-1 Gene

No Compound Related Data Available

Transcripts for RNU6-1 Gene

mRNA/cDNA for RNU6-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU6-1 Gene

No ASD Table

Relevant External Links for RNU6-1 Gene

GeneLoc Exon Structure for
RNU6-1
ECgene alternative splicing isoforms for
RNU6-1

Expression for RNU6-1 Gene

mRNA expression in normal human tissues for RNU6-1 Gene

genes like me logo Genes that share expression patterns with RNU6-1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RNU6-1 Gene

Orthologs for RNU6-1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU6-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia U6 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U6 36
  • 100 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Gm26427 36
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia U6 36
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia U6 36
  • 100 (a)
OneToOne
Species with no ortholog for RNU6-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU6-1 Gene

ENSEMBL:
Gene Tree for RNU6-1 (if available)
TreeFam:
Gene Tree for RNU6-1 (if available)

Paralogs for RNU6-1 Gene

No data available for Paralogs for RNU6-1 Gene

Variants for RNU6-1 Gene

Sequence variations from dbSNP and Humsavar for RNU6-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs28434258 -- 67,841,955(+) TTGAG(A/T)TGGAG upstream-variant-2KB
rs12917587 -- 67,841,279(+) CTGGG(A/G)GATGA upstream-variant-2KB
rs34132927 -- 67,841,734(+) TAACC(-/A)AAAAG upstream-variant-2KB
rs75440859 -- 67,841,544(+) GGCTT(C/G)AGTTC upstream-variant-2KB
rs116723550 -- 67,841,041(+) TCCGC(G/T)TTCCT upstream-variant-2KB

Relevant External Links for RNU6-1 Gene

HapMap Linkage Disequilibrium report
RNU6-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU6-1 Gene

Disorders for RNU6-1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for RNU6-1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
poikiloderma with neutropenia
  • clericuzio type poikiloderma with neutropenia
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for RNU6-1

Genetic Association Database (GAD)
RNU6-1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNU6-1
genes like me logo Genes that share disorders with RNU6-1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RNU6-1 Gene

Publications for RNU6-1 Gene

  1. Common genetic variation and performance on standardized cognitive tests. (PMID: 20125193) Cirulli E.T. … Goldstein D.B. (Eur. J. Hum. Genet. 2010) 3 48 67
  2. Multiple, dispersed human U6 small nuclear RNA genes with varied transcriptional efficiencies. (PMID: 12711679) Domitrovich A.M. … Kunkel G.R. (Nucleic Acids Res. 2003) 2 3
  3. Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. (PMID: 3360322) Kunkel G.R. … Pederson T. (Genes Dev. 1988) 2 3
  4. Identification of suitable reference genes for hepatic microRNA quantitation. (PMID: 24606728) Lamba V. … Lamba J.K. (BMC Res Notes 2014) 3
  5. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. (PMID: 25263594) Guo R. … Shi Y. (Mol. Cell 2014) 3

Products for RNU6-1 Gene

Sources for RNU6-1 Gene

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