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Aliases for RNU5E-4P Gene

Subcategory (RNA class) for RNU5E-4P Gene

snRNA

Aliases for RNU5E-4P Gene

  • RNA, U5E Small Nuclear 4, Pseudogene 2 3 5

External Ids for RNU5E-4P Gene

ORGUL Members for RNU5E-4P Gene

Previous GeneCards Identifiers for RNU5E-4P Gene

  • GC00U933762
  • GC01M011970

Summaries for RNU5E-4P Gene

GeneCards Summary for RNU5E-4P Gene

RNU5E-4P (RNA, U5E Small Nuclear 4, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU5E-4P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U5_snRNA: U5 RNA is a component of both types of known spliceosome. The precise function of this molecule is unknown, though it is known that the 5' loop is required for splice site selection and p220 binding, and that both the 3' stem-loop and the Sm site are important for Sm protein binding and cap methylation.

  • U5 spliceosomal RNA: U5 RNA is a component of both types of known spliceosome. The precise function of this molecule is unknown, though it is known that the 5' loop is required for splice site selection and p220 binding, and that both the 3' stem-loop and the Sm site are important for Sm protein binding and cap methylation.

View fRNAdb secondary structures for RNU5E-4P

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU5E-4P Gene

Genomics for RNU5E-4P Gene

Regulatory Elements for RNU5E-4P Gene

Enhancers for RNU5E-4P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G011879 2.1 VISTA FANTOM5 Ensembl ENCODE dbSUPER 12.3 +27.9 27917 4.1 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B YY1 ZNF766 KLF13 SP5 PLOD1 KIAA2013 NPPB RNU5E-1 RNU5E-4P NPPA-AS1 LOC102724659 C1orf167 LOC390997 ENSG00000226849
GH01G011978 2 FANTOM5 Ensembl ENCODE dbSUPER 11.2 -72.8 -72805 8.6 MLX CREB3L1 AGO1 ZFP64 DMAP1 YBX1 YY1 ZNF143 MCM3 SP3 MFN2 MIIP TNFRSF1B PLOD1 KIAA2013 RNU5E-1 RNU5E-4P NPPB EXOSC10 MTHFR
GH01G011989 1.4 FANTOM5 ENCODE dbSUPER 11.2 -80.6 -80583 2.2 FOXA2 KLF17 YY1 CEBPB PPARG NR2F2 MXD3 HNF4A ZBTB33 ZBTB26 MFN2 MIIP PLOD1 KIAA2013 RNU5E-1 RNU5E-4P NPPB NPPA ENSG00000270914
GH01G011873 1.1 dbSUPER 12.1 +35.2 35226 2.0 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF766 RNU5E-1 RNU5E-4P NPPA-AS1 MFN2 PLOD1 KIAA2013 LOC102724659 C1orf167 LOC390997 MTHFR
GH01G011872 1.1 dbSUPER 12.1 +35.9 35940 3.7 HDGF PKNOX1 CREB3L1 MLX ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF766 RNU5E-1 RNU5E-4P NPPA-AS1 MFN2 PLOD1 KIAA2013 LOC102724659 C1orf167 MTHFR LOC390997
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU5E-4P on UCSC Golden Path with GeneCards custom track

Promoters for RNU5E-4P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000001459 927 2401 MLX CREB3L1 AGO1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3

Genomic Location for RNU5E-4P Gene

Chromosome:
1
Start:
11,909,808 bp from pter
End:
11,909,927 bp from pter
Size:
120 bases
Orientation:
Minus strand

Genomic View for RNU5E-4P Gene

Genes around RNU5E-4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU5E-4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU5E-4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5E-4P Gene

ORGUL Member Location for RNU5E-4P Gene

ORGUL Member Location for RNU5E-4P gene

Proteins for RNU5E-4P Gene

Post-translational modifications for RNU5E-4P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5E-4P Gene

Domains & Families for RNU5E-4P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5E-4P Gene

Function for RNU5E-4P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU5E-4P Gene

Localization for RNU5E-4P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU5E-4P Gene

Pathways & Interactions for RNU5E-4P Gene

SuperPathways for RNU5E-4P Gene

No Data Available

Interacting Proteins for RNU5E-4P Gene

Gene Ontology (GO) - Biological Process for RNU5E-4P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU5E-4P Gene

Transcripts for RNU5E-4P Gene

fRNAdb Secondary structures for RNU5E-4P Gene

  • RF00020;U5;ABBA01003062.1/49061-48942

mRNA/cDNA for RNU5E-4P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5E-4P Gene

No ASD Table

Relevant External Links for RNU5E-4P Gene

GeneLoc Exon Structure for
RNU5E-4P
ECgene alternative splicing isoforms for
RNU5E-4P

Expression for RNU5E-4P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU5E-4P Gene

genes like me logo Genes that share expression patterns with RNU5E-4P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU5E-4P Gene

Orthologs for RNU5E-4P Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU5E-4P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U5 35
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U5 35
  • 77 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U5 35
  • 69 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U5 35
  • 62 (a)
ManyToMany
Species where no ortholog for RNU5E-4P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5E-4P Gene

ENSEMBL:
Gene Tree for RNU5E-4P (if available)
TreeFam:
Gene Tree for RNU5E-4P (if available)

Paralogs for RNU5E-4P Gene

No data available for Paralogs for RNU5E-4P Gene

Variants for RNU5E-4P Gene

Relevant External Links for RNU5E-4P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU5E-4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU5E-4P Gene

Disorders for RNU5E-4P Gene

No disorders were found for RNU5E-4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU5E-4P Gene

Publications for RNU5E-4P Gene

  1. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1
  2. Domain analysis of human U5 RNA. Cap trimethylation, protein binding, and spliceosome assembly. (PMID: 8702566) Hinz M. … Bindereif A. (J. Biol. Chem. 1996) 1
  3. The spliceosomal snRNAs of Caenorhabditis elegans. (PMID: 2339054) Thomas J. … Blumenthal T. (Nucleic Acids Res. 1990) 1

Products for RNU5E-4P Gene

Sources for RNU5E-4P Gene

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