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Aliases for RNU5B-1 Gene

Subcategory (RNA class) for RNU5B-1 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU5B-1 Gene

  • RNA, U5B Small Nuclear 1 2 3 5
  • RNA, U5B Small Nuclear Pseudogene 1 3
  • RNA, U5B Small Nuclear 2
  • RNU5B-1P 3
  • RNU5B 3
  • U5B1 3

External Ids for RNU5B-1 Gene

ORGUL Members for RNU5B-1 Gene

Previous HGNC Symbols for RNU5B-1 Gene

  • RNU5B

Previous GeneCards Identifiers for RNU5B-1 Gene

  • GC15P063387
  • GC15P065597
  • GC15P042421

Summaries for RNU5B-1 Gene

GeneCards Summary for RNU5B-1 Gene

RNU5B-1 (RNA, U5B Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class.

Additional gene information for RNU5B-1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU5B-1 Gene

Genomics for RNU5B-1 Gene

GeneHancer (GH) Regulatory Elements for RNU5B-1 Gene

Promoters and enhancers for RNU5B-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I065303 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE dbSUPER 550.8 -0.2 -206 2.2 CLOCK MLX FEZF1 DMAP1 IRF4 YY1 E2F8 ZNF143 SP3 NFYC GC15M065305 GC15P068442 RNU5B-1 PARP16 ZNF609 TRIP4 INTS14 PDCD7 SLC24A1 ENSG00000264937
GH15I065305 Enhancer 0.3 ENCODE 550.8 +1.3 1261 0.1 ZNF384 GC15M065305 GC15P068442 RNU5B-1 IGDCC3 CLPX CILP GC15M065309
GH15I065183 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.8 -119.9 -119915 3 FOXA2 ARID4B SIN3A DMAP1 ZBTB7B YY1 POLR2B ZNF766 CBX5 ZNF207 GC15P069458 GC15P069459 GC15P069460 GC15P069461 GC15P069462 GC15P069464 GC15P069465 GC15P069466 PIR37257 CLPX
GH15I065376 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.9 +73.3 73282 2.5 ZNF133 ARID4B SIN3A DMAP1 GLI4 ZNF2 ZNF48 GLIS2 KLF13 SP3 IGDCC3 INTS14 PDCD7 ZNF609 IGDCC4 ENSG00000260773 PARP16 RNU5B-1 SLC24A1 ENSG00000259635
GH15I065274 Enhancer 1.1 Ensembl ENCODE 12.9 -29.0 -29039 1.3 HDAC1 FOXA2 THRB ZNF335 ZNF366 SCRT2 FOS ATF7 NCOA1 ZEB2 PARP16 RNU5B-1 RNU6-686P CILP CLPX IGDCC3 SNORA24B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNU5B-1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RNU5B-1 gene promoter:

Genomic Locations for RNU5B-1 Gene

Genomic Locations for RNU5B-1 Gene
chr15:65,304,677-65,304,793
(GRCh38/hg38)
Size:
117 bases
Orientation:
Plus strand
chr15:65,597,015-65,597,131
(GRCh37/hg19)

Genomic View for RNU5B-1 Gene

Genes around RNU5B-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU5B-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU5B-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5B-1 Gene

Proteins for RNU5B-1 Gene

Post-translational modifications for RNU5B-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5B-1 Gene

Domains & Families for RNU5B-1 Gene

Gene Families for RNU5B-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU5B-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5B-1 Gene

Function for RNU5B-1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU5B-1 Gene

Localization for RNU5B-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU5B-1 Gene

Pathways & Interactions for RNU5B-1 Gene

SuperPathways for RNU5B-1 Gene

No Data Available

Interacting Proteins for RNU5B-1 Gene

Gene Ontology (GO) - Biological Process for RNU5B-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU5B-1 Gene

Drugs & Compounds for RNU5B-1 Gene

No Compound Related Data Available

Transcripts for RNU5B-1 Gene

mRNA/cDNA for RNU5B-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5B-1 Gene

No ASD Table

Relevant External Links for RNU5B-1 Gene

GeneLoc Exon Structure for
RNU5B-1
ECgene alternative splicing isoforms for
RNU5B-1

Expression for RNU5B-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU5B-1 Gene

genes like me logo Genes that share expression patterns with RNU5B-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU5B-1 Gene

Orthologs for RNU5B-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU5B-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U5 34
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rnu5g 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U5 34
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U5 34 34 34
  • 93 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U5 34
  • 90 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia U5 34
  • 88 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia U5 34
  • 82 (a)
ManyToMany
Species where no ortholog for RNU5B-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5B-1 Gene

ENSEMBL:
Gene Tree for RNU5B-1 (if available)
TreeFam:
Gene Tree for RNU5B-1 (if available)

Paralogs for RNU5B-1 Gene

No data available for Paralogs for RNU5B-1 Gene

Variants for RNU5B-1 Gene

Sequence variations from dbSNP and Humsavar for RNU5B-1 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000096893 -- 65,304,547(+) A/G upstream_transcript_variant
rs1000128222 -- 65,304,365(+) C/T upstream_transcript_variant
rs1000294648 -- 65,304,396(+) C/G upstream_transcript_variant
rs1002185253 -- 65,304,839(+) T/C downstream_transcript_variant
rs1002229900 -- 65,304,646(+) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RNU5B-1 Gene

Variant ID Type Subtype PubMed ID
nsv457182 CNV loss 19166990
nsv457183 CNV loss 19166990
nsv569705 CNV loss 21841781
nsv569706 CNV loss 21841781

Additional Variant Information for RNU5B-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU5B-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU5B-1 Gene

Disorders for RNU5B-1 Gene

Additional Disease Information for RNU5B-1

No disorders were found for RNU5B-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU5B-1 Gene

Publications for RNU5B-1 Gene

  1. Three novel functional variants of human U5 small nuclear RNA. (PMID: 1310151) Sontheimer EJ … Steitz JA (Molecular and cellular biology 1992) 2 3 58
  2. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L … Tomasson MH (The Journal of clinical investigation 2012) 3 58
  3. The nuclear 5S RNAs from chicken, rat and man. U5 RNAs are encoded by multiple genes. (PMID: 6164980) Krol A … Branlant C (Nucleic acids research 1981) 3 58

Products for RNU5B-1 Gene

Sources for RNU5B-1 Gene

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