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Aliases for RNU5B-1 Gene

Subcategory (RNA class) for RNU5B-1 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU5B-1 Gene

  • RNA, U5B Small Nuclear 1 2 3
  • RNA, U5B Small Nuclear Pseudogene 1 3
  • RNA, U5B Small Nuclear 2
  • RNU5B-1P 3
  • RNU5B 3
  • U5B1 3

External Ids for RNU5B-1 Gene

ORGUL Members for RNU5B-1 Gene

Previous HGNC Symbols for RNU5B-1 Gene

  • RNU5B

Previous GeneCards Identifiers for RNU5B-1 Gene

  • GC15P063387
  • GC15P065597
  • GC15P042421

Summaries for RNU5B-1 Gene

GeneCards Summary for RNU5B-1 Gene

RNU5B-1 (RNA, U5B Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU5B-1 Gene

Genomics for RNU5B-1 Gene

Regulatory Elements for RNU5B-1 Gene

Genomic Location for RNU5B-1 Gene

Start:
65,304,677 bp from pter
End:
65,304,793 bp from pter
Size:
117 bases
Orientation:
Plus strand

Genomic View for RNU5B-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNU5B-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5B-1 Gene

Proteins for RNU5B-1 Gene

Post-translational modifications for RNU5B-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5B-1 Gene

Domains for RNU5B-1 Gene

Gene Families for RNU5B-1 Gene

HGNC:
  • snRNA :ncRNAs / Small nuclear RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU5B-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5B-1 Gene

Function for RNU5B-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RNU5B-1 Gene

Localization for RNU5B-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU5B-1 Gene

Pathways for RNU5B-1 Gene

SuperPathways for RNU5B-1 Gene

No Data Available

Interacting Proteins for RNU5B-1 Gene

Gene Ontology (GO) - Biological Process for RNU5B-1 Gene

None

No data available for Pathways by source for RNU5B-1 Gene

Transcripts for RNU5B-1 Gene

mRNA/cDNA for RNU5B-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNU5B-1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5B-1 Gene

No ASD Table

Relevant External Links for RNU5B-1 Gene

GeneLoc Exon Structure for
RNU5B-1
ECgene alternative splicing isoforms for
RNU5B-1

Expression for RNU5B-1 Gene

mRNA expression in normal human tissues for RNU5B-1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with RNU5B-1: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for RNU5B-1 Gene

Orthologs for RNU5B-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU5B-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U5 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U5 36
  • 93 (a)
OneToMany
U5 36
  • 93 (a)
OneToMany
U5 36
  • 92 (a)
OneToMany
dog
(Canis familiaris)
Mammalia U5 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rnu5g 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U5 36
  • 88 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U5 36
  • 90 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia U5 36
  • 82 (a)
ManyToMany
Species with no ortholog for RNU5B-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5B-1 Gene

ENSEMBL:
Gene Tree for RNU5B-1 (if available)
TreeFam:
Gene Tree for RNU5B-1 (if available)

Paralogs for RNU5B-1 Gene

No data available for Paralogs for RNU5B-1 Gene

Variants for RNU5B-1 Gene

Sequence variations from dbSNP and Humsavar for RNU5B-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs502236 -- 65,305,176(-) ATTGA(A/G)ATGCG downstream-variant-500B
rs525725 -- 65,304,946(-) CTTGT(C/T)GGAAG downstream-variant-500B
rs525907 -- 65,304,882(-) CGATT(A/G)AAGCG downstream-variant-500B
rs526794 -- 65,304,800(-) AACAG(C/T)TTTAT downstream-variant-500B
rs680552 -- 65,304,253(+) TCATT(G/T)ACTTG upstream-variant-2KB

Relevant External Links for RNU5B-1 Gene

HapMap Linkage Disequilibrium report
RNU5B-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RNU5B-1 Gene

Disorders for RNU5B-1 Gene

No disorders were found for RNU5B-1 Gene.

No data available for UniProtKB/Swiss-Prot for RNU5B-1 Gene

Publications for RNU5B-1 Gene

  1. Three novel functional variants of human U5 small nuclear RNA. (PMID: 1310151) Sontheimer E.J. … Steitz J.A. (Mol. Cell. Biol. 1992) 2 3
  2. The nuclear 5S RNAs from chicken, rat and man. U5 RNAs are encoded by multiple genes. (PMID: 6164980) Krol A. … Branlant C. (Nucleic Acids Res. 1981) 3
  3. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3

Products for RNU5B-1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate RNU5B-1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RNU5B-1
    • Block miRNA regulation of RNU5B-1 using miScript Target Protectors

    Sources for RNU5B-1 Gene

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