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Aliases for RNU5B-1 Gene

Subcategory (RNA class) for RNU5B-1 Gene


Quality Score for this RNA gene is


Aliases for RNU5B-1 Gene

  • RNA, U5B Small Nuclear 1 2 3 5
  • RNA, U5B Small Nuclear Pseudogene 1 3
  • RNA, U5B Small Nuclear 2
  • RNU5B-1P 3
  • RNU5B 3
  • U5B1 3

External Ids for RNU5B-1 Gene

ORGUL Members for RNU5B-1 Gene

Previous HGNC Symbols for RNU5B-1 Gene

  • RNU5B

Previous GeneCards Identifiers for RNU5B-1 Gene

  • GC15P063387
  • GC15P065597
  • GC15P042421

Summaries for RNU5B-1 Gene

GeneCards Summary for RNU5B-1 Gene

RNU5B-1 (RNA, U5B Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU5B-1 Gene

Genomics for RNU5B-1 Gene

Regulatory Elements for RNU5B-1 Gene

Enhancers around RNU5B-1 on UCSC Golden Path with GeneCards custom track

Promoters for RNU5B-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001453093 -277 1601 CREB3L1 MLX FEZF1 DMAP1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21

Genomic Location for RNU5B-1 Gene

65,304,677 bp from pter
65,304,793 bp from pter
117 bases
Plus strand

Genomic View for RNU5B-1 Gene

Genes around RNU5B-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU5B-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU5B-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5B-1 Gene

Proteins for RNU5B-1 Gene

Post-translational modifications for RNU5B-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5B-1 Gene

Domains & Families for RNU5B-1 Gene

Gene Families for RNU5B-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU5B-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5B-1 Gene

Function for RNU5B-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU5B-1 Gene

Localization for RNU5B-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU5B-1 Gene

Pathways & Interactions for RNU5B-1 Gene

SuperPathways for RNU5B-1 Gene

No Data Available

Interacting Proteins for RNU5B-1 Gene

Gene Ontology (GO) - Biological Process for RNU5B-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNU5B-1 Gene

Transcripts for RNU5B-1 Gene

mRNA/cDNA for RNU5B-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5B-1 Gene

No ASD Table

Relevant External Links for RNU5B-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNU5B-1 Gene

mRNA expression in normal human tissues for RNU5B-1 Gene

genes like me logo Genes that share expression patterns with RNU5B-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU5B-1 Gene

Orthologs for RNU5B-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU5B-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia U5 35
  • 97 (a)
(Mus musculus)
Mammalia Rnu5g 35
  • 96 (a)
(Canis familiaris)
Mammalia U5 35
  • 95 (a)
(Bos Taurus)
Mammalia U5 35 35 35
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia U5 35
  • 90 (a)
(Monodelphis domestica)
Mammalia U5 35
  • 88 (a)
(Anolis carolinensis)
Reptilia U5 35
  • 82 (a)
Species where no ortholog for RNU5B-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5B-1 Gene

Gene Tree for RNU5B-1 (if available)
Gene Tree for RNU5B-1 (if available)

Paralogs for RNU5B-1 Gene

No data available for Paralogs for RNU5B-1 Gene

Variants for RNU5B-1 Gene

Sequence variations from dbSNP and Humsavar for RNU5B-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs11071837 -- 65,304,155(+) AAATT(A/G)TCAAA upstream-variant-2KB
rs113245459 -- 65,304,030(+) CAATT(G/T)TAAAC upstream-variant-2KB
rs113247559 -- 65,304,793(+) AGGCT(A/G)TATAA nc-transcript-variant
rs113755379 -- 65,305,063(+) TGAGC(A/G)GATCA downstream-variant-500B
rs114366143 -- 65,302,760(+) GGGCT(C/T)GGTGG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU5B-1 Gene

Variant ID Type Subtype PubMed ID
nsv457182 CNV loss 19166990
nsv457183 CNV loss 19166990
nsv569705 CNV loss 21841781
nsv569706 CNV loss 21841781

Relevant External Links for RNU5B-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU5B-1 Gene

Disorders for RNU5B-1 Gene

Relevant External Links for RNU5B-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNU5B-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU5B-1 Gene

Publications for RNU5B-1 Gene

  1. Three novel functional variants of human U5 small nuclear RNA. (PMID: 1310151) Sontheimer E.J. … Steitz J.A. (Mol. Cell. Biol. 1992) 2 3 64
  2. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3 64
  3. The nuclear 5S RNAs from chicken, rat and man. U5 RNAs are encoded by multiple genes. (PMID: 6164980) Krol A. … Branlant C. (Nucleic Acids Res. 1981) 3 64

Products for RNU5B-1 Gene

Sources for RNU5B-1 Gene

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