Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RNU5A-1 Gene

Subcategory (RNA class) for RNU5A-1 Gene


Quality Score for this RNA gene is


Aliases for RNU5A-1 Gene

  • RNA, U5A Small Nuclear 1 2 3 5
  • RNA, U5C Small Nuclear 2 3
  • RNA, U5A Small Nuclear 2
  • RNU5A 3
  • RNU5C 3
  • RNU5 3
  • U5B1 3
  • U5A 3

External Ids for RNU5A-1 Gene

ORGUL Members for RNU5A-1 Gene

Previous HGNC Symbols for RNU5A-1 Gene

  • RNU5C
  • RNU5A

Previous GeneCards Identifiers for RNU5A-1 Gene

  • GC15P065590
  • GC15P065675
  • GC15P065763

Summaries for RNU5A-1 Gene

GeneCards Summary for RNU5A-1 Gene

RNU5A-1 (RNA, U5A Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class. Diseases associated with RNU5A-1 include Poikiloderma With Neutropenia.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU5A-1 Gene

Genomics for RNU5A-1 Gene

Regulatory Elements for RNU5A-1 Gene

Enhancers for RNU5A-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around RNU5A-1 on UCSC Golden Path with GeneCards custom track

Promoters for RNU5A-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RNU5A-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU5A-1 Gene

65,296,051 bp from pter
65,296,167 bp from pter
117 bases
Plus strand

Genomic View for RNU5A-1 Gene

Genes around RNU5A-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU5A-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU5A-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5A-1 Gene

Proteins for RNU5A-1 Gene

Post-translational modifications for RNU5A-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5A-1 Gene

Domains & Families for RNU5A-1 Gene

Gene Families for RNU5A-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU5A-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5A-1 Gene

Function for RNU5A-1 Gene

Phenotypes for RNU5A-1 Gene

GenomeRNAi human phenotypes for RNU5A-1:
genes like me logo Genes that share phenotypes with RNU5A-1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU5A-1 Gene

Localization for RNU5A-1 Gene

Subcellular locations from

Jensen Localization Image for RNU5A-1 Gene COMPARTMENTS Subcellular localization image for RNU5A-1 gene
Compartment Confidence
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RNU5A-1 Gene

Pathways & Interactions for RNU5A-1 Gene

SuperPathways for RNU5A-1 Gene

No Data Available

Interacting Proteins for RNU5A-1 Gene

Gene Ontology (GO) - Biological Process for RNU5A-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNU5A-1 Gene

Drugs & Compounds for RNU5A-1 Gene

No Compound Related Data Available

Transcripts for RNU5A-1 Gene

mRNA/cDNA for RNU5A-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5A-1 Gene

No ASD Table

Relevant External Links for RNU5A-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNU5A-1 Gene

mRNA expression in normal human tissues for RNU5A-1 Gene

mRNA differential expression in normal tissues according to GTEx for RNU5A-1 Gene

This gene is overexpressed in Testis (x5.0).
genes like me logo Genes that share expression patterns with RNU5A-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU5A-1 Gene

Orthologs for RNU5A-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU5A-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia U5 35
  • 88 (a)
(Canis familiaris)
Mammalia U5 35
  • 90 (a)
(Monodelphis domestica)
Mammalia U5 35
  • 91 (a)
(Mus musculus)
Mammalia Gm25313 35
  • 97 (a)
(Ornithorhynchus anatinus)
Mammalia U5 35
  • 91 (a)
(Pan troglodytes)
Mammalia U5 35
  • 99 (a)
(Anolis carolinensis)
Reptilia U5 35
  • 85 (a)
Species where no ortholog for RNU5A-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5A-1 Gene

Gene Tree for RNU5A-1 (if available)
Gene Tree for RNU5A-1 (if available)

Paralogs for RNU5A-1 Gene

No data available for Paralogs for RNU5A-1 Gene

Variants for RNU5A-1 Gene

Sequence variations from dbSNP and Humsavar for RNU5A-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs2925841 -- 65,295,930(+) TGAGA(A/C)TTTTG upstream-variant-2KB
rs680524 -- 65,294,422(+) ggaga(C/T)tgagg upstream-variant-2KB
rs57465853 -- 65,295,013(+) ATTAT(-/TTAT)ATAAT upstream-variant-2KB
rs59413222 -- 65,295,019(+) TATAT(-/AATAT)GTAAT upstream-variant-2KB
rs59453837 -- 65,294,545(+) AAAAA(-/A)GGAAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU5A-1 Gene

Variant ID Type Subtype PubMed ID
nsv457182 CNV loss 19166990
nsv457183 CNV loss 19166990
nsv569705 CNV loss 21841781
nsv569706 CNV loss 21841781

Relevant External Links for RNU5A-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU5A-1 Gene

Disorders for RNU5A-1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for RNU5A-1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
poikiloderma with neutropenia
  • poikiloderma with neutropenia clericuzio type
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with RNU5A-1: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for RNU5A-1 Gene

Publications for RNU5A-1 Gene

  1. Three novel functional variants of human U5 small nuclear RNA. (PMID: 1310151) Sontheimer E.J. … Steitz J.A. (Mol. Cell. Biol. 1992) 2 3 65
  2. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. (PMID: 25263594) Guo R. … Shi Y. (Mol. Cell 2014) 3 65
  3. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3 65
  4. Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA. (PMID: 23022480) Shchepachev V. … Azzalin C.M. (Cell Rep 2012) 3 65
  5. The multifunctional human p100 protein 'hooks' methylated ligands. (PMID: 17632523) Shaw N. … Rao Z. (Nat. Struct. Mol. Biol. 2007) 3 65

Products for RNU5A-1 Gene

Sources for RNU5A-1 Gene