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Aliases for RNU5A-1 Gene

Subcategory (RNA class) for RNU5A-1 Gene


Quality Score for this RNA gene is


Aliases for RNU5A-1 Gene

  • RNA, U5A Small Nuclear 1 2 3 5
  • RNA, U5C Small Nuclear 2 3
  • RNA, U5A Small Nuclear 2
  • RNU5A 3
  • RNU5C 3
  • RNU5 3
  • U5B1 3
  • U5A 3

External Ids for RNU5A-1 Gene

ORGUL Members for RNU5A-1 Gene

Previous HGNC Symbols for RNU5A-1 Gene

  • RNU5C
  • RNU5A

Previous GeneCards Identifiers for RNU5A-1 Gene

  • GC15P065590
  • GC15P065675
  • GC15P065763

Summaries for RNU5A-1 Gene

GeneCards Summary for RNU5A-1 Gene

RNU5A-1 (RNA, U5A Small Nuclear 1) is an RNA Gene, and is affiliated with the snRNA class. Diseases associated with RNU5A-1 include Poikiloderma With Neutropenia.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU5A-1 Gene

Genomics for RNU5A-1 Gene

Regulatory Elements for RNU5A-1 Gene

Enhancers around RNU5A-1 on UCSC Golden Path with GeneCards custom track

Promoters for RNU5A-1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001796017 1849 201 TBP ARID4B RAD21 YY1 SCRT2 ZNF143 CREM DEK MIXL1 THAP11

Genomic Location for RNU5A-1 Gene

65,296,051 bp from pter
65,296,167 bp from pter
117 bases
Plus strand

Genomic View for RNU5A-1 Gene

Genes around RNU5A-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU5A-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU5A-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU5A-1 Gene

Proteins for RNU5A-1 Gene

Post-translational modifications for RNU5A-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU5A-1 Gene

Domains & Families for RNU5A-1 Gene

Gene Families for RNU5A-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU5A-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU5A-1 Gene

Function for RNU5A-1 Gene

Phenotypes for RNU5A-1 Gene

GenomeRNAi human phenotypes for RNU5A-1:
genes like me logo Genes that share phenotypes with RNU5A-1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU5A-1 Gene

Localization for RNU5A-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU5A-1 Gene

Pathways & Interactions for RNU5A-1 Gene

SuperPathways for RNU5A-1 Gene

No Data Available

Interacting Proteins for RNU5A-1 Gene

Gene Ontology (GO) - Biological Process for RNU5A-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNU5A-1 Gene

Transcripts for RNU5A-1 Gene

mRNA/cDNA for RNU5A-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU5A-1 Gene

No ASD Table

Relevant External Links for RNU5A-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNU5A-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNU5A-1 Gene

mRNA differential expression in normal tissues according to GTEx for RNU5A-1 Gene

This gene is overexpressed in Testis (x5.0).
genes like me logo Genes that share expression patterns with RNU5A-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU5A-1 Gene

Orthologs for RNU5A-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU5A-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia U5 35
  • 99 (a)
(Mus musculus)
Mammalia Gm25313 35
  • 97 (a)
(Monodelphis domestica)
Mammalia U5 35
  • 91 (a)
(Ornithorhynchus anatinus)
Mammalia U5 35
  • 91 (a)
(Canis familiaris)
Mammalia U5 35
  • 90 (a)
(Bos Taurus)
Mammalia U5 35
  • 88 (a)
(Anolis carolinensis)
Reptilia U5 35
  • 85 (a)
Species where no ortholog for RNU5A-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU5A-1 Gene

Gene Tree for RNU5A-1 (if available)
Gene Tree for RNU5A-1 (if available)

Paralogs for RNU5A-1 Gene

No data available for Paralogs for RNU5A-1 Gene

Variants for RNU5A-1 Gene

Sequence variations from dbSNP and Humsavar for RNU5A-1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs11071836 -- 65,295,391(+) ATAGG(A/G)GAAAT upstream-variant-2KB
rs111341760 -- 65,295,658(+) AGGTA(A/G)AGGTT upstream-variant-2KB
rs113915857 -- 65,296,340(+) GTATA(-/TTCACT)TATGT downstream-variant-500B
rs117850999 -- 65,295,942(+) ATGCA(C/G)AATTT upstream-variant-2KB
rs118159132 -- 65,296,179(+) GTAAT(C/T)CAACA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for RNU5A-1 Gene

Variant ID Type Subtype PubMed ID
nsv457182 CNV loss 19166990
nsv457183 CNV loss 19166990
nsv569705 CNV loss 21841781
nsv569706 CNV loss 21841781

Relevant External Links for RNU5A-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU5A-1 Gene

Disorders for RNU5A-1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for RNU5A-1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
poikiloderma with neutropenia
  • clericuzio type poikiloderma with neutropenia
- elite association - COSMIC cancer census association via MalaCards
genes like me logo Genes that share disorders with RNU5A-1: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for RNU5A-1 Gene

Publications for RNU5A-1 Gene

  1. Three novel functional variants of human U5 small nuclear RNA. (PMID: 1310151) Sontheimer E.J. … Steitz J.A. (Mol. Cell. Biol. 1992) 2 3 64
  2. BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. (PMID: 25263594) Guo R. … Shi Y. (Mol. Cell 2014) 3 64
  3. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3 64
  4. Mpn1, mutated in poikiloderma with neutropenia protein 1, is a conserved 3'-to-5' RNA exonuclease processing U6 small nuclear RNA. (PMID: 23022480) Shchepachev V. … Azzalin C.M. (Cell Rep 2012) 3 64
  5. The multifunctional human p100 protein 'hooks' methylated ligands. (PMID: 17632523) Shaw N. … Rao Z. (Nat. Struct. Mol. Biol. 2007) 3 64

Products for RNU5A-1 Gene

Sources for RNU5A-1 Gene

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