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Aliases for RNU4-48P Gene

Subcategory (RNA class) for RNU4-48P Gene

snRNA

Aliases for RNU4-48P Gene

  • RNA, U4 Small Nuclear 48, Pseudogene 2 3 5

External Ids for RNU4-48P Gene

ORGUL Members for RNU4-48P Gene

Previous GeneCards Identifiers for RNU4-48P Gene

  • GC02P128231

Summaries for RNU4-48P Gene

GeneCards Summary for RNU4-48P Gene

RNU4-48P (RNA, U4 Small Nuclear 48, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU4-48P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U4_snRNA: U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6.

  • U4 spliceosomal RNA: U4 small nuclear RNA (U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to re-fold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6.

View fRNAdb secondary structures for RNU4-48P

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU4-48P Gene

Genomics for RNU4-48P Gene

Regulatory Elements for RNU4-48P Gene

Enhancers for RNU4-48P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G127507 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10.5 +37.5 37474 4.9 PKNOX1 SIN3A FEZF1 ZNF2 GATA2 FOS ZNF263 TSHZ1 MAFF SMARCA4 SFT2D3 ENSG00000236682 MYO7B RNU4-48P LIMS2 ERCC3 IWS1 ENSG00000231731 AMMECR1L MAP3K2
GH02G127437 1 ENCODE 10.7 -33.9 -33864 1.3 HNRNPUL1 FOXA2 ATF1 MLX ARID4B DMAP1 ZNF48 YY1 SLC30A9 GATA2 ERCC3 ENSG00000236682 MAP3K2 RNU4-48P BIN1 LIMS2 MIR4783 ENSG00000231731
GH02G127498 0.9 ENCODE dbSUPER 10.9 +26.4 26396 0.1 CEBPB ZNF384 CEBPG DPF2 EP300 FOXA1 IRF9 GATA3 CEBPA FOS MYO7B ENSG00000231731 RNU4-48P ERCC3 GC02M127501
GH02G127365 0.9 Ensembl dbSUPER 10.8 -106.7 -106734 0.6 ZNF362 HCFC1 ZNF384 ZSCAN5C GLIS1 ZNF143 PRDM10 THAP11 ENSG00000236682 MAP3K2 RNU4-48P LOC100506922 LOC105373606
GH02G127354 0.7 dbSUPER 10.8 -117.5 -117453 1.3 SOX5 SOX13 GATAD2A CTCF REST KLF4 RAD21 GATA3 GATA2 BCL6 ERCC3 ENSG00000236682 MAP3K2 RNU4-48P LOC105373606 LOC100506922
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU4-48P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU4-48P Gene

Chromosome:
2
Start:
127,472,234 bp from pter
End:
127,472,415 bp from pter
Size:
182 bases
Orientation:
Plus strand

Genomic View for RNU4-48P Gene

Genes around RNU4-48P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU4-48P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU4-48P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU4-48P Gene

ORGUL Member Location for RNU4-48P Gene

ORGUL Member Location for RNU4-48P gene

Proteins for RNU4-48P Gene

Post-translational modifications for RNU4-48P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU4-48P Gene

Domains & Families for RNU4-48P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU4-48P Gene

Function for RNU4-48P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU4-48P Gene

Localization for RNU4-48P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU4-48P Gene

Pathways & Interactions for RNU4-48P Gene

SuperPathways for RNU4-48P Gene

No Data Available

Interacting Proteins for RNU4-48P Gene

Gene Ontology (GO) - Biological Process for RNU4-48P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU4-48P Gene

Drugs & Compounds for RNU4-48P Gene

No Compound Related Data Available

Transcripts for RNU4-48P Gene

fRNAdb Secondary structures for RNU4-48P Gene

  • RF00015;U4;AADD01022117.1/25867-26048

mRNA/cDNA for RNU4-48P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU4-48P Gene

No ASD Table

Relevant External Links for RNU4-48P Gene

GeneLoc Exon Structure for
RNU4-48P
ECgene alternative splicing isoforms for
RNU4-48P

Expression for RNU4-48P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU4-48P Gene

genes like me logo Genes that share expression patterns with RNU4-48P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU4-48P Gene

Orthologs for RNU4-48P Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU4-48P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U4 35
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U4 35
  • 75 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia U4 35
  • 59 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25806 35
  • 55 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia U4 35
  • 51 (a)
OneToOne
Species where no ortholog for RNU4-48P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU4-48P Gene

ENSEMBL:
Gene Tree for RNU4-48P (if available)
TreeFam:
Gene Tree for RNU4-48P (if available)

Paralogs for RNU4-48P Gene

No data available for Paralogs for RNU4-48P Gene

Variants for RNU4-48P Gene

Relevant External Links for RNU4-48P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU4-48P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU4-48P Gene

Disorders for RNU4-48P Gene

No disorders were found for RNU4-48P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU4-48P Gene

Publications for RNU4-48P Gene

  1. Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment. (PMID: 11163207) Vidovic I. … Ficner R. (Mol. Cell 2000) 1
  2. A spliceosomal recycling factor that reanneals U4 and U6 small nuclear ribonucleoprotein particles. (PMID: 9452384) Raghunathan P.L. … Guthrie C. (Science 1998) 1
  3. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1
  4. The spliceosomal snRNAs of Caenorhabditis elegans. (PMID: 2339054) Thomas J. … Blumenthal T. (Nucleic Acids Res. 1990) 1

Products for RNU4-48P Gene

Sources for RNU4-48P Gene

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