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Aliases for RNU2-4P Gene

Subcategory (RNA class) for RNU2-4P Gene

snRNA

Aliases for RNU2-4P Gene

  • RNA, U2 Small Nuclear 4, Pseudogene 2 3 5
  • RNA, U2 Small Nuclear Pseudogene 2 2 3
  • RNA, U2 Small Nuclear 4 (Pseudogene) 3
  • RNU2P2 3
  • U2/7 3
  • U2 3

External Ids for RNU2-4P Gene

Previous HGNC Symbols for RNU2-4P Gene

  • RNU2P2

Previous GeneCards Identifiers for RNU2-4P Gene

  • GC17M038832
  • GC17M041467
  • GC17M037225

Summaries for RNU2-4P Gene

GeneCards Summary for RNU2-4P Gene

RNU2-4P (RNA, U2 Small Nuclear 4, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU2-4P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U2_snRNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

  • U2 spliceosomal RNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenosine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

View fRNAdb secondary structures for RNU2-4P

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU2-4P Gene

Genomics for RNU2-4P Gene

Regulatory Elements for RNU2-4P Gene

Promoters for RNU2-4P Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around RNU2-4P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU2-4P Gene

Chromosome:
17
Start:
43,387,226 bp from pter
End:
43,387,517 bp from pter
Size:
292 bases
Orientation:
Minus strand

Genomic View for RNU2-4P Gene

Genes around RNU2-4P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU2-4P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU2-4P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU2-4P Gene

ORGUL Member Location for RNU2-4P Gene

ORGUL Member Location for RNU2-4P gene

Proteins for RNU2-4P Gene

Post-translational modifications for RNU2-4P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU2-4P Gene

Domains & Families for RNU2-4P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU2-4P Gene

Function for RNU2-4P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU2-4P Gene

Localization for RNU2-4P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU2-4P Gene

Pathways & Interactions for RNU2-4P Gene

SuperPathways for RNU2-4P Gene

No Data Available

Interacting Proteins for RNU2-4P Gene

Gene Ontology (GO) - Biological Process for RNU2-4P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU2-4P Gene

Drugs & Compounds for RNU2-4P Gene

No Compound Related Data Available

Transcripts for RNU2-4P Gene

fRNAdb Secondary structures for RNU2-4P Gene

  • RF00004;U2;ABBA01028418.1/3128-3319

mRNA/cDNA for RNU2-4P Gene

Alternative Splicing Database (ASD) splice patterns (SP) for RNU2-4P Gene

No ASD Table

Relevant External Links for RNU2-4P Gene

GeneLoc Exon Structure for
RNU2-4P
ECgene alternative splicing isoforms for
RNU2-4P

Expression for RNU2-4P Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RNU2-4P Gene

Orthologs for RNU2-4P Gene

Evolution for RNU2-4P Gene

ENSEMBL:
Gene Tree for RNU2-4P (if available)
TreeFam:
Gene Tree for RNU2-4P (if available)

No data available for Orthologs for RNU2-4P Gene

Paralogs for RNU2-4P Gene

No data available for Paralogs for RNU2-4P Gene

Variants for RNU2-4P Gene

Relevant External Links for RNU2-4P Gene

HapMap Linkage Disequilibrium report
RNU2-4P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU2-4P Gene

Disorders for RNU2-4P Gene

No disorders were found for RNU2-4P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU2-4P Gene

Publications for RNU2-4P Gene

  1. Human genes for U2 small nuclear RNA are tandemly repeated. (PMID: 6201719) Van Arsdell S.W. … Weiner A.M. (Mol. Cell. Biol. 1984) 2 3 67
  2. Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. (PMID: 22751105) Chu L. … Tomasson M.H. (J. Clin. Invest. 2012) 3
  3. Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines. (PMID: 11350032) Berglund J.A. … Schultz S.C. (RNA 2001) 1
  4. A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architecture. (PMID: 11424937) Newby M.I. … Greenbaum N.L. (RNA 2001) 1
  5. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1

Products for RNU2-4P Gene

Sources for RNU2-4P Gene

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