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Aliases for RNU2-18P Gene

Subcategory (RNA class) for RNU2-18P Gene

snRNA

Aliases for RNU2-18P Gene

  • RNA, U2 Small Nuclear 18, Pseudogene 2 3 5

External Ids for RNU2-18P Gene

ORGUL Members for RNU2-18P Gene

Previous GeneCards Identifiers for RNU2-18P Gene

  • GC00U935686

Summaries for RNU2-18P Gene

GeneCards Summary for RNU2-18P Gene

RNU2-18P (RNA, U2 Small Nuclear 18, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU2-18P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U2_snRNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

  • U2 spliceosomal RNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenosine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU2-18P Gene

Genomics for RNU2-18P Gene

Regulatory Elements for RNU2-18P Gene

Enhancers for RNU2-18P Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNU2-18P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU2-18P Gene

Chromosome:
10
Start:
16,476,003 bp from pter
End:
16,476,164 bp from pter
Size:
162 bases
Orientation:
Plus strand

Genomic View for RNU2-18P Gene

Genes around RNU2-18P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU2-18P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU2-18P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for RNU2-18P Gene

ORGUL Member Location for RNU2-18P gene

No data available for RefSeq DNA sequence for RNU2-18P Gene

Proteins for RNU2-18P Gene

Post-translational modifications for RNU2-18P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU2-18P Gene

Domains & Families for RNU2-18P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU2-18P Gene

Function for RNU2-18P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU2-18P Gene

Localization for RNU2-18P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU2-18P Gene

Pathways & Interactions for RNU2-18P Gene

SuperPathways for RNU2-18P Gene

No Data Available

Interacting Proteins for RNU2-18P Gene

Gene Ontology (GO) - Biological Process for RNU2-18P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU2-18P Gene

Drugs & Compounds for RNU2-18P Gene

No Compound Related Data Available

Transcripts for RNU2-18P Gene

mRNA/cDNA for RNU2-18P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU2-18P Gene

No ASD Table

Relevant External Links for RNU2-18P Gene

GeneLoc Exon Structure for
RNU2-18P
ECgene alternative splicing isoforms for
RNU2-18P

Expression for RNU2-18P Gene

mRNA expression in normal human tissues for RNU2-18P Gene

genes like me logo Genes that share expression patterns with RNU2-18P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RNU2-18P Gene

Orthologs for RNU2-18P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU2-18P Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia U2 36
  • 55 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm22970 36
  • 44 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U2 36
  • 48 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia U2 36
  • 86 (a)
OneToOne
chicken
(Gallus gallus)
Aves U2 36
  • 53 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia U2 36
  • 59 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea U2 36
  • 50 (a)
ManyToMany
U2 36
  • 38 (a)
ManyToMany
U2 36
  • 51 (a)
ManyToMany
U2 36
  • 51 (a)
ManyToMany
Species with no ortholog for RNU2-18P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU2-18P Gene

ENSEMBL:
Gene Tree for RNU2-18P (if available)
TreeFam:
Gene Tree for RNU2-18P (if available)

Paralogs for RNU2-18P Gene

No data available for Paralogs for RNU2-18P Gene

Variants for RNU2-18P Gene

Relevant External Links for RNU2-18P Gene

HapMap Linkage Disequilibrium report
RNU2-18P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU2-18P Gene

Disorders for RNU2-18P Gene

No disorders were found for RNU2-18P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU2-18P Gene

Publications for RNU2-18P Gene

  1. Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines. (PMID: 11350032) Berglund J.A. … Schultz S.C. (RNA 2001) 1
  2. A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architecture. (PMID: 11424937) Newby M.I. … Greenbaum N.L. (RNA 2001) 1
  3. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1
  4. The spliceosomal snRNAs of Caenorhabditis elegans. (PMID: 2339054) Thomas J. … Blumenthal T. (Nucleic Acids Res. 1990) 1

Products for RNU2-18P Gene

Sources for RNU2-18P Gene

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