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Aliases for RNU2-11P Gene

Subcategory (RNA class) for RNU2-11P Gene

snRNA

Aliases for RNU2-11P Gene

  • RNA, U2 Small Nuclear 11, Pseudogene 2 3 5

External Ids for RNU2-11P Gene

ORGUL Members for RNU2-11P Gene

Previous GeneCards Identifiers for RNU2-11P Gene

  • GC03M195657
  • GC00U934497

Summaries for RNU2-11P Gene

GeneCards Summary for RNU2-11P Gene

RNU2-11P (RNA, U2 Small Nuclear 11, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU2-11P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U2_snRNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

  • U2 spliceosomal RNA: U2 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenosine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing.

Additional gene information for RNU2-11P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU2-11P Gene

Genomics for RNU2-11P Gene

Regulatory Elements for RNU2-11P Gene

Enhancers for RNU2-11P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H195862 1.4 Ensembl ENCODE dbSUPER 11.4 +65.3 65305 1 HDAC1 HDGF RB1 ARID4B SIN3A RAD21 GLIS2 ZNF143 ATF7 CREM ENSG00000271662 RNU2-11P GC03P195867 LINC01983
GH03H195859 1.4 Ensembl ENCODE dbSUPER 11.2 +69.1 69098 1 HDAC1 TBL1XR1 RB1 ARNT NFXL1 ZNF2 RAD21 YY1 RFX5 TCF12 UBXN7 RNU2-11P ACAP2 LINC00969 ENSG00000271662 ENSG00000229178 LINC01983 KIF3AP1
GH03H195855 0.9 ENCODE 11.3 +72.3 72310 1 HDAC1 TBP PKNOX1 ATF1 TBL1XR1 SIN3A TCF12 ZNF766 GATA2 ETV6 MUC4 RNU2-11P LINC00969 LINC01983 KIF3AP1
GH03H195869 0.8 ENCODE dbSUPER 12.2 +58.1 58065 2 ZFHX2 GLIS1 MAX MYC EGR2 RNU2-11P MUC4 TNK2 SDHAP2 ENSG00000229178 GC03P195867 PIR40505
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU2-11P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU2-11P Gene

Chromosome:
3
Start:
195,928,589 bp from pter
End:
195,928,775 bp from pter
Size:
187 bases
Orientation:
Minus strand

Genomic View for RNU2-11P Gene

Genes around RNU2-11P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU2-11P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU2-11P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU2-11P Gene

ORGUL Member Location for RNU2-11P Gene

ORGUL Member Location for RNU2-11P gene

Proteins for RNU2-11P Gene

Post-translational modifications for RNU2-11P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU2-11P Gene

Domains & Families for RNU2-11P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU2-11P Gene

Function for RNU2-11P Gene

Phenotypes From GWAS Catalog for RNU2-11P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU2-11P Gene

Localization for RNU2-11P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU2-11P Gene

Pathways & Interactions for RNU2-11P Gene

SuperPathways for RNU2-11P Gene

No Data Available

Interacting Proteins for RNU2-11P Gene

Gene Ontology (GO) - Biological Process for RNU2-11P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU2-11P Gene

Drugs & Compounds for RNU2-11P Gene

No Compound Related Data Available

Transcripts for RNU2-11P Gene

mRNA/cDNA for RNU2-11P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU2-11P Gene

No ASD Table

Relevant External Links for RNU2-11P Gene

GeneLoc Exon Structure for
RNU2-11P
ECgene alternative splicing isoforms for
RNU2-11P

Expression for RNU2-11P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU2-11P Gene

genes like me logo Genes that share expression patterns with RNU2-11P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU2-11P Gene

Orthologs for RNU2-11P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU2-11P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U2 34
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U2 34 34
  • 72 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm22984 34
  • 70 (a)
OneToMany
Gm25106 34
  • 68 (a)
OneToMany
dog
(Canis familiaris)
Mammalia U2 34 34
  • 67 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia U2 34
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia U2 34
  • 56 (a)
ManyToMany
chicken
(Gallus gallus)
Aves U2 34
  • 56 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia U2 34
  • 54 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea U2 34 34 34 34
  • 51 (a)
ManyToMany
Species where no ortholog for RNU2-11P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU2-11P Gene

ENSEMBL:
Gene Tree for RNU2-11P (if available)
TreeFam:
Gene Tree for RNU2-11P (if available)

Paralogs for RNU2-11P Gene

No data available for Paralogs for RNU2-11P Gene

Variants for RNU2-11P Gene

Relevant External Links for RNU2-11P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU2-11P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU2-11P Gene

Disorders for RNU2-11P Gene

No disorders were found for RNU2-11P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU2-11P Gene

Publications for RNU2-11P Gene

  1. A conserved pseudouridine modification in eukaryotic U2 snRNA induces a change in branch-site architecture. (PMID: 11424937) Newby MI … Greenbaum NL (RNA (New York, N.Y.) 2001) 1
  2. Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines. (PMID: 11350032) Berglund JA … Schultz SC (RNA (New York, N.Y.) 2001) 1
  3. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  4. The spliceosomal snRNAs of Caenorhabditis elegans. (PMID: 2339054) Thomas J … Blumenthal T (Nucleic acids research 1990) 1

Products for RNU2-11P Gene

Sources for RNU2-11P Gene

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