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Aliases for RNU12 Gene

Subcategory (RNA class) for RNU12 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU12 Gene

  • RNA, U12 Small Nuclear 2 3 5
  • RNA, U12 Small Nuclear Pseudogene 2 3
  • RNA, U12 Small Nuclear 1 2 3
  • DJ222E13.7 3
  • RNU12-1 3
  • RNU12P 3
  • RNU12L 3

External Ids for RNU12 Gene

ORGUL Members for RNU12 Gene

Previous HGNC Symbols for RNU12 Gene

  • RNU12P

Previous GeneCards Identifiers for RNU12 Gene

  • GC00U990629
  • GC0XP045252
  • GC0XP045818
  • GC0XP046037
  • GC0XP046747
  • GC0XP046876
  • GC22P041340
  • GC22P043010
  • GC22P025971
  • GC22P043013
  • GC22P043016

Summaries for RNU12 Gene

GeneCards Summary for RNU12 Gene

RNU12 (RNA, U12 Small Nuclear) is an RNA Gene, and is affiliated with the snRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU12 Gene

Genomics for RNU12 Gene

Regulatory Elements for RNU12 Gene

Enhancers for RNU12 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G042618 1.6 Ensembl ENCODE dbSUPER 0.4 +5.6 5639 3.9 FOXA2 PKNOX1 CREB3L1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 FEZF1 XRCC6 RRP7BP CYB5R3 RPL5P34 RN7SKP80 ENSG00000270022 RNU12 ATP5L2
GH22G042617 0.9 ENCODE dbSUPER 0.7 +2.6 2617 0.6 PAF1 HDAC1 RFX1 MXD4 SSRP1 ZNF366 POLR2A ZNF692 TCF7 PRDM1 SERHL2 A4GALT ENSG00000270022 RNU12 ATP5L2
GH22G042623 1.1 ENCODE dbSUPER 0.4 +8.4 8427 1.1 ZNF493 ZFP64 ZNF48 ZEB1 ZNF138 ZNF354C KLF7 ZNF680 ZNF654 SP3 RN7SKP80 RPL5P34 RRP7BP LOC100506679 CYB5R3 SNU13 ENSG00000270022 RNU12 ATP5L2
GH22G042635 1.3 Ensembl ENCODE dbSUPER 0.3 +20.8 20812 2.0 KLF1 JUN MAX KLF17 ZSCAN9 ZFHX2 POLR2A RCOR1 FOS EGR2 CYB5R3 A4GALT SERHL2 ATP5L2 RNU12 ENSG00000270022
GH22G042637 0.8 dbSUPER 0.3 +22.5 22465 0.9 CTCF SAP130 ZNF2 RAD21 ZNF121 ZBTB48 ZNF143 SMC3 GATAD2A ZNF263 CYB5R3 SERHL2 ATP5L2 RNU12 ENSG00000270022
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU12 on UCSC Golden Path with GeneCards custom track

Promoters for RNU12 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000146788 -544 2201 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3

Genomic Location for RNU12 Gene

Chromosome:
22
Start:
42,615,244 bp from pter
End:
42,615,393 bp from pter
Size:
150 bases
Orientation:
Plus strand

Genomic View for RNU12 Gene

Genes around RNU12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU12 Gene

Proteins for RNU12 Gene

Post-translational modifications for RNU12 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU12 Gene

Domains & Families for RNU12 Gene

Gene Families for RNU12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU12: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU12 Gene

Function for RNU12 Gene

Phenotypes for RNU12 Gene

GenomeRNAi human phenotypes for RNU12:
genes like me logo Genes that share phenotypes with RNU12: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU12 Gene

Localization for RNU12 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU12 Gene

Pathways & Interactions for RNU12 Gene

SuperPathways for RNU12 Gene

No Data Available

Interacting Proteins for RNU12 Gene

Gene Ontology (GO) - Biological Process for RNU12 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU12 Gene

Transcripts for RNU12 Gene

mRNA/cDNA for RNU12 Gene

(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNU12 Gene

RNA, U12 small nuclear:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNU12 Gene

No ASD Table

Relevant External Links for RNU12 Gene

GeneLoc Exon Structure for
RNU12
ECgene alternative splicing isoforms for
RNU12

Expression for RNU12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU12 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNU12 Gene:

RNU12

SOURCE GeneReport for Unigene cluster for RNU12 Gene:

Hs.574857
genes like me logo Genes that share expression patterns with RNU12: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU12 Gene

Orthologs for RNU12 Gene

Evolution for RNU12 Gene

ENSEMBL:
Gene Tree for RNU12 (if available)
TreeFam:
Gene Tree for RNU12 (if available)

No data available for Orthologs for RNU12 Gene

Paralogs for RNU12 Gene

No data available for Paralogs for RNU12 Gene

Variants for RNU12 Gene

Sequence variations from dbSNP and Humsavar for RNU12 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000195915 -- 42,615,512(+) AGTTG(C/G/T)TTGGC downstream-variant-500B, upstream-variant-2KB
rs1000643617 -- 42,615,182(+) ACGAT(A/G)GTCAT upstream-variant-2KB
rs1001940679 -- 42,613,332(+) GTAAG(G/T)GCTGG intron-variant, upstream-variant-2KB
rs1002540638 -- 42,614,254(+) ATGAG(A/G)CATCG intron-variant, upstream-variant-2KB
rs1002646476 -- 42,613,652(+) GCTAC(C/T)TGGGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU12 Gene

Variant ID Type Subtype PubMed ID
esv2758839 CNV gain+loss 17122850
nsv428391 CNV gain 18775914
nsv524028 CNV loss 19592680

Relevant External Links for RNU12 Gene

Human Gene Mutation Database (HGMD)
RNU12
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU12 Gene

Disorders for RNU12 Gene

Relevant External Links for RNU12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNU12

No disorders were found for RNU12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU12 Gene

Publications for RNU12 Gene

  1. U12 snRNA in vertebrates: evolutionary conservation of 5' sequences implicated in splicing of pre-mRNAs containing a minor class of introns. (PMID: 7489523) Tarn W.Y. … Steitz J.A. (RNA 1995) 2 3 64
  2. Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. (PMID: 25586593) Madan V. … Koeffler H.P. (Nat Commun 2015) 3 64
  3. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PMID: 15146077) Will C.L. … Luehrmann R. (RNA 2004) 3 64
  4. Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. (PMID: 2973606) Montzka K.A. … Steitz J.A. (Proc. Natl. Acad. Sci. U.S.A. 1988) 3 64

Products for RNU12 Gene

Sources for RNU12 Gene

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