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Aliases for RNU12 Gene

Subcategory (RNA class) for RNU12 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU12 Gene

  • RNA, U12 Small Nuclear 2 3 5
  • RNA, U12 Small Nuclear Pseudogene 2 3
  • RNA, U12 Small Nuclear 1 2 3
  • DJ222E13.7 3
  • RNU12-1 3
  • RNU12P 3
  • RNU12L 3

External Ids for RNU12 Gene

ORGUL Members for RNU12 Gene

Previous HGNC Symbols for RNU12 Gene

  • RNU12P

Previous GeneCards Identifiers for RNU12 Gene

  • GC00U990629
  • GC0XP045252
  • GC0XP045818
  • GC0XP046037
  • GC0XP046747
  • GC0XP046876
  • GC22P041340
  • GC22P043010
  • GC22P025971
  • GC22P043013
  • GC22P043016

Summaries for RNU12 Gene

GeneCards Summary for RNU12 Gene

RNU12 (RNA, U12 Small Nuclear) is an RNA Gene, and is affiliated with the snRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU12 Gene

Genomics for RNU12 Gene

Regulatory Elements for RNU12 Gene

Enhancers for RNU12 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F042618 1.4 Ensembl ENCODE 0.4 +5.6 5639 3.9 PKNOX1 MLX ARNT CREB3L1 ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZNF2 RRP7BP XRCC6 CYB5R3 RPL5P34 RN7SKP80 ENSG00000270022 RNU12 ATP5L2
GH22F042617 0.6 ENCODE 0.8 +2.6 2617 0.6 PAF1 RFX1 MXD4 SSRP1 POLR2A ZNF366 ZNF692 TCF7 PRDM1 SERHL2 A4GALT ENSG00000270022 RNU12 ATP5L2
GH22F042623 0.9 ENCODE 0.4 +8.4 8427 1.1 ZNF493 ZFP64 ZNF48 ZEB1 ZNF354C ZNF138 KLF7 ZNF680 SP3 ZNF654 RN7SKP80 RRP7BP RPL5P34 CYB5R3 OGFRP1 ENSG00000273366 ENSG00000233903 NAGA LOC100506679 ARFGAP3
GH22F042635 1 Ensembl ENCODE 0.3 +20.8 20812 2.0 KLF1 JUN MAX KLF17 ZSCAN9 ZFHX2 POLR2A RCOR1 FOS EGR2 CYB5R3 A4GALT SERHL2 ATP5L2 ENSG00000270022 RNU12
GH22F042640 0.6 Ensembl 0.3 +24.9 24857 0.2 ZNF121 ZNF692 ZBTB8A REST ZNF623 ZNF264 RPL5P34 OGFRP1 ENSG00000273366 ENSG00000233903 NAGA ARFGAP3 FAM109B CCDC134 ATP5L2 ENSG00000270022
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU12 on UCSC Golden Path with GeneCards custom track

Promoters for RNU12 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000673526 -644 2401 CREB3L1 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3

Genomic Location for RNU12 Gene

Chromosome:
22
Start:
42,615,244 bp from pter
End:
42,615,393 bp from pter
Size:
150 bases
Orientation:
Plus strand

Genomic View for RNU12 Gene

Genes around RNU12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU12 Gene

Proteins for RNU12 Gene

Post-translational modifications for RNU12 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU12 Gene

Domains & Families for RNU12 Gene

Gene Families for RNU12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU12: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU12 Gene

Function for RNU12 Gene

Phenotypes for RNU12 Gene

GenomeRNAi human phenotypes for RNU12:
genes like me logo Genes that share phenotypes with RNU12: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU12 Gene

Localization for RNU12 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU12 Gene

Pathways & Interactions for RNU12 Gene

SuperPathways for RNU12 Gene

No Data Available

Interacting Proteins for RNU12 Gene

Gene Ontology (GO) - Biological Process for RNU12 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU12 Gene

Transcripts for RNU12 Gene

mRNA/cDNA for RNU12 Gene

(2) Additional mRNA sequences :
(4) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNU12 Gene

RNA, U12 small nuclear:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNU12 Gene

No ASD Table

Relevant External Links for RNU12 Gene

GeneLoc Exon Structure for
RNU12
ECgene alternative splicing isoforms for
RNU12

Expression for RNU12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNU12 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNU12 Gene:

RNU12

SOURCE GeneReport for Unigene cluster for RNU12 Gene:

Hs.574857
genes like me logo Genes that share expression patterns with RNU12: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU12 Gene

Orthologs for RNU12 Gene

Evolution for RNU12 Gene

ENSEMBL:
Gene Tree for RNU12 (if available)
TreeFam:
Gene Tree for RNU12 (if available)

No data available for Orthologs for RNU12 Gene

Paralogs for RNU12 Gene

No data available for Paralogs for RNU12 Gene

Variants for RNU12 Gene

Sequence variations from dbSNP and Humsavar for RNU12 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs112472831 -- 42,613,531(+) GAGGC(A/G)GGAGG intron-variant, upstream-variant-2KB
rs113007903 -- 42,615,030(+) GGTGC(C/T)GGCTG upstream-variant-2KB
rs113058028 -- 42,614,672(+) AATGA(C/G)GAGCG intron-variant, upstream-variant-2KB
rs113098266 -- 42,615,168(+) CTCAA(A/C)AGTCA upstream-variant-2KB
rs113930938 -- 42,615,848(+) TGATA(C/T)AACCC downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU12 Gene

Variant ID Type Subtype PubMed ID
nsv428391 CNV gain 18775914
nsv524028 CNV loss 19592680
esv2758839 CNV gain+loss 17122850

Relevant External Links for RNU12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU12 Gene

Disorders for RNU12 Gene

Relevant External Links for RNU12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNU12

No disorders were found for RNU12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU12 Gene

Publications for RNU12 Gene

  1. U12 snRNA in vertebrates: evolutionary conservation of 5' sequences implicated in splicing of pre-mRNAs containing a minor class of introns. (PMID: 7489523) Tarn W.Y. … Steitz J.A. (RNA 1995) 2 3 64
  2. Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome. (PMID: 25586593) Madan V. … Koeffler H.P. (Nat Commun 2015) 3 64
  3. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PMID: 15146077) Will C.L. … Luehrmann R. (RNA 2004) 3 64
  4. Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. (PMID: 2973606) Montzka K.A. … Steitz J.A. (Proc. Natl. Acad. Sci. U.S.A. 1988) 3 64

Products for RNU12 Gene

Sources for RNU12 Gene

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