Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RNU11 Gene

Subcategory (RNA class) for RNU11 Gene


Quality Score for this RNA gene is


Aliases for RNU11 Gene

  • RNA, U11 Small Nuclear 2 3 5
  • RNU11-1 3
  • U11 3

External Ids for RNU11 Gene

Previous GeneCards Identifiers for RNU11 Gene

  • GC00U990630
  • GC01U901037
  • GC01P028849
  • GC01P028975
  • GC01P027228
  • GC01P028649

Summaries for RNU11 Gene

GeneCards Summary for RNU11 Gene

RNU11 (RNA, U11 Small Nuclear) is an RNA Gene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU11 Gene - the ORGUL cluster for this gene includes several descriptions:

  • U11_snRNA: U11 snRNA plays a role in splicing of the minor U12-dependent class of eukaryotic nuclear introns, similar to U1 snRNA in the major class spliceosome it base pairs to the conserved 5' splice site sequence.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • U11 spliceosomal RNA: The U11 small nuclear (snRNA), together with U4atac/U6atac, U5, and U12 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU11 Gene

Genomics for RNU11 Gene

Regulatory Elements for RNU11 Gene

Promoters for RNU11 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000003895 200 1201 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3

Genomic Location for RNU11 Gene

28,648,600 bp from pter
28,648,734 bp from pter
135 bases
Plus strand

Genomic View for RNU11 Gene

Genes around RNU11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU11 Gene

ORGUL Member Location for RNU11 Gene

ORGUL Member Location for RNU11 gene

Proteins for RNU11 Gene

Post-translational modifications for RNU11 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU11 Gene

Domains & Families for RNU11 Gene

Gene Families for RNU11 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU11: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU11 Gene

Function for RNU11 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU11 Gene

Localization for RNU11 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNU11 gene
Compartment Confidence
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RNU11 Gene

Pathways & Interactions for RNU11 Gene

SuperPathways for RNU11 Gene

No Data Available

Interacting Proteins for RNU11 Gene

Gene Ontology (GO) - Biological Process for RNU11 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNU11 Gene

Drugs & Compounds for RNU11 Gene

No Compound Related Data Available

Transcripts for RNU11 Gene

mRNA/cDNA for RNU11 Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNU11 Gene

RNA, U11 small nuclear:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNU11 Gene

No ASD Table

Relevant External Links for RNU11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNU11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU11 Gene

mRNA differential expression in normal tissues according to GTEx for RNU11 Gene

This gene is overexpressed in Muscle - Skeletal (x6.4).

NURSA nuclear receptor signaling pathways regulating expression of RNU11 Gene:


SOURCE GeneReport for Unigene cluster for RNU11 Gene:

genes like me logo Genes that share expression patterns with RNU11: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU11 Gene

Orthologs for RNU11 Gene

Evolution for RNU11 Gene

Gene Tree for RNU11 (if available)
Gene Tree for RNU11 (if available)

No data available for Orthologs for RNU11 Gene

Paralogs for RNU11 Gene

No data available for Paralogs for RNU11 Gene

Variants for RNU11 Gene

Sequence variations from dbSNP and Humsavar for RNU11 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000371673 -- 28,647,701(+) ACCCC(A/C)GTCTC intron-variant, upstream-variant-2KB
rs1000425411 -- 28,647,480(+) ACGAG(A/G/T)TCTCT intron-variant, upstream-variant-2KB
rs1000465216 -- 28,648,516(+) GAAAT(A/G)AAGAG nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs1000938791 -- 28,649,200(+) GGCCA(A/G)GATGG downstream-variant-500B, upstream-variant-2KB
rs1002476033 -- 28,648,768(+) TACGC(A/G/T)TTTGG nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for RNU11 Gene

Variant ID Type Subtype PubMed ID
nsv545920 CNV loss 21841781

Relevant External Links for RNU11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU11 Gene

Disorders for RNU11 Gene

Relevant External Links for RNU11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNU11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU11 Gene

Publications for RNU11 Gene

  1. Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc. (PMID: 2973606) Montzka K.A. … Steitz J.A. (Proc. Natl. Acad. Sci. U.S.A. 1988) 1 2 3 64
  2. An ancient mechanism for splicing control: U11 snRNP as an activator of alternative splicing. (PMID: 20347424) Verbeeren J. … Frilander M.J. (Mol. Cell 2010) 3 64
  3. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome. (PMID: 15146077) Will C.L. … Luehrmann R. (RNA 2004) 3 64
  4. Identification and classification of conserved RNA secondary structures in the human genome. (PMID: 16628248) Pedersen J.S. … Haussler D. (PLoS Comput. Biol. 2006) 1
  5. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C. … Chen R. (Nucleic Acids Res. 2005) 1

Products for RNU11 Gene

Sources for RNU11 Gene

Loading form....