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Aliases for RNU1-64P Gene

Subcategory (RNA class) for RNU1-64P Gene

snRNA

Aliases for RNU1-64P Gene

  • RNA, U1 Small Nuclear 64, Pseudogene 2 3 5

External Ids for RNU1-64P Gene

ORGUL Members for RNU1-64P Gene

Previous GeneCards Identifiers for RNU1-64P Gene

  • GC00U935493

Summaries for RNU1-64P Gene

GeneCards Summary for RNU1-64P Gene

RNU1-64P (RNA, U1 Small Nuclear 64, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU1-64P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

Additional gene information for RNU1-64P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU1-64P Gene

Genomics for RNU1-64P Gene

Regulatory Elements for RNU1-64P Gene

Enhancers for RNU1-64P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H011426 1.6 FANTOM5 Ensembl ENCODE 10.7 +74.8 74798 3 HDGF PKNOX1 FOXA2 MLX ZNF133 YBX1 ZNF2 SLC30A9 GLIS2 FOS HIVEP1 ENSG00000233656 ENSG00000242753 LOC101928253 MRPL48P1 LOC100422564 MIR5689HG LINC02522 NEDD9 RNU1-64P
GH06H011138 1.3 FANTOM5 Ensembl ENCODE 11.3 +364.4 364354 2 BATF FOSL1 GATA3 EED FOS ZNF600 ATF7 RUNX3 IKZF2 ZNF10 RNU1-64P THAP12P5 ENSG00000247925 ERVFRD-1 TMEM170B NEDD9 GC06P011137 ENSG00000271245
GH06H011425 0.9 ENCODE 10.7 +77.9 77852 1 ELF3 FOXA2 MLX ARID4B DMAP1 RAD21 THRB RARA RCOR1 MIXL1 NEDD9 RNU1-64P THAP12P5 ENSG00000247925 LOC105374929 ENSG00000242753
GH06H011467 0.7 ENCODE 11.7 +35.6 35644 1 ZNF687 YBX1 EBF1 DPF2 RELA IKZF1 SCRT2 CUX1 MLLT1 RUNX3 RNU1-64P THAP12P5 ENSG00000247925 ENSG00000233656 ENSG00000242753 LOC105374929
GH06H011310 0.7 Ensembl dbSUPER 10.9 +193.4 193371 0 CTCF POLR2A RNU1-64P NEDD9 THAP12P5 ENSG00000247925 LOC105374925 GC06M011330
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU1-64P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU1-64P Gene

Chromosome:
6
Start:
11,503,509 bp from pter
End:
11,503,671 bp from pter
Size:
163 bases
Orientation:
Minus strand

Genomic View for RNU1-64P Gene

Genes around RNU1-64P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU1-64P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU1-64P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-64P Gene

ORGUL Member Location for RNU1-64P Gene

ORGUL Member Location for RNU1-64P gene

Proteins for RNU1-64P Gene

Post-translational modifications for RNU1-64P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-64P Gene

Domains & Families for RNU1-64P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-64P Gene

Function for RNU1-64P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-64P Gene

Localization for RNU1-64P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU1-64P Gene

Pathways & Interactions for RNU1-64P Gene

SuperPathways for RNU1-64P Gene

No Data Available

Interacting Proteins for RNU1-64P Gene

Gene Ontology (GO) - Biological Process for RNU1-64P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU1-64P Gene

Drugs & Compounds for RNU1-64P Gene

No Compound Related Data Available

Transcripts for RNU1-64P Gene

mRNA/cDNA for RNU1-64P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-64P Gene

No ASD Table

Relevant External Links for RNU1-64P Gene

GeneLoc Exon Structure for
RNU1-64P
ECgene alternative splicing isoforms for
RNU1-64P

Expression for RNU1-64P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU1-64P Gene

genes like me logo Genes that share expression patterns with RNU1-64P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU1-64P Gene

Orthologs for RNU1-64P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU1-64P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 34
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U1 34
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm25938 34
  • 63 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia U1 34
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia U1 34
  • 55 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia U1 34
  • 47 (a)
ManyToMany
chicken
(Gallus gallus)
Aves U1 34
  • 59 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia U1 34
  • 64 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii U1 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34 34
  • 54 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea U1 34
  • 55 (a)
OneToMany
Species where no ortholog for RNU1-64P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNU1-64P Gene

ENSEMBL:
Gene Tree for RNU1-64P (if available)
TreeFam:
Gene Tree for RNU1-64P (if available)

Paralogs for RNU1-64P Gene

No data available for Paralogs for RNU1-64P Gene

Variants for RNU1-64P Gene

Relevant External Links for RNU1-64P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU1-64P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU1-64P Gene

Disorders for RNU1-64P Gene

No disorders were found for RNU1-64P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU1-64P Gene

Publications for RNU1-64P Gene

  1. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba PS … Laird-Offringa IA (The Journal of biological chemistry 2001) 1
  2. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  3. Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. (PMID: 7984237) Oubridge C … Nagai K (Nature 1994) 1
  4. Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains. (PMID: 2405391) Kretzner L … Rosbash M (Proceedings of the National Academy of Sciences of the United States of America 1990) 1

Products for RNU1-64P Gene

Sources for RNU1-64P Gene

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