Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RNU1-58P Gene

Subcategory (RNA class) for RNU1-58P Gene

snRNA

Aliases for RNU1-58P Gene

  • RNA, U1 Small Nuclear 58, Pseudogene 2 3 5

External Ids for RNU1-58P Gene

Previous GeneCards Identifiers for RNU1-58P Gene

  • GC07P139944
  • GC00U935405

Summaries for RNU1-58P Gene

GeneCards Summary for RNU1-58P Gene

RNU1-58P (RNA, U1 Small Nuclear 58, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU1-58P Gene - the ORGUL cluster for this gene includes several descriptions:

  • snRNA: A small nuclear RNA molecule involved in pre-mRNA splicing and processing.

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

View fRNAdb secondary structures for RNU1-58P

Additional gene information for RNU1-58P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU1-58P Gene

Genomics for RNU1-58P Gene

Regulatory Elements for RNU1-58P Gene

Enhancers for RNU1-58P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H140084 1.1 Ensembl ENCODE 11.1 -156.8 -156762 0 HDGF PKNOX1 TBL1XR1 BATF ZNF143 ATF7 ETV6 RUNX3 CREM IKZF2 KDM7A RNU1-58P ENSG00000251728 GC07M140095 LOC105375533
GH07H140304 1 Ensembl ENCODE 10.9 +63.1 63076 1 HDGF CTCF ARNT ZSCAN4 RAD21 FOSL1 CC2D1A MTA3 CTBP1 SMC3 KDM7A RNU6-797P RNU1-58P LOC105375534 RNA5SP247
GH07H140310 0.8 ENCODE 10.8 +68.7 68666 0 ELF3 SOX13 ESRRA FOXA2 SAP130 ARID4B RARA TEAD3 CTBP1 GATA3 KDM7A RNU6-797P RNU1-58P LOC105375534 RNA5SP247
GH07H140220 0.6 ENCODE 11.2 -21.7 -21689 1 BCOR SMARCE1 TBL1XR1 ZMYM3 DPF2 CTBP1 KDM1A RCOR1 FOS KDM7A RNU1-58P JHDM1D-AS1 GC07P140221 GC07M140210 RNU6-797P
GH07H140196 0.6 ENCODE 11 -45.0 -44955 0 ZNF766 ATF1 ZNF512 ADNP TRIM24 MGA RNU1-58P GC07M140210 RNU6-797P PIR48297
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNU1-58P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU1-58P Gene

Chromosome:
7
Start:
140,241,870 bp from pter
End:
140,242,032 bp from pter
Size:
163 bases
Orientation:
Plus strand

Genomic View for RNU1-58P Gene

Genes around RNU1-58P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU1-58P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU1-58P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-58P Gene

ORGUL Member Location for RNU1-58P Gene

ORGUL Member Location for RNU1-58P gene

Proteins for RNU1-58P Gene

Post-translational modifications for RNU1-58P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-58P Gene

Domains & Families for RNU1-58P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-58P Gene

Function for RNU1-58P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-58P Gene

Localization for RNU1-58P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU1-58P Gene

Pathways & Interactions for RNU1-58P Gene

SuperPathways for RNU1-58P Gene

No Data Available

Interacting Proteins for RNU1-58P Gene

Gene Ontology (GO) - Biological Process for RNU1-58P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU1-58P Gene

Drugs & Compounds for RNU1-58P Gene

No Compound Related Data Available

Transcripts for RNU1-58P Gene

fRNAdb Secondary structures for RNU1-58P Gene

  • FR203726

mRNA/cDNA for RNU1-58P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-58P Gene

No ASD Table

Relevant External Links for RNU1-58P Gene

GeneLoc Exon Structure for
RNU1-58P
ECgene alternative splicing isoforms for
RNU1-58P

Expression for RNU1-58P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU1-58P Gene

genes like me logo Genes that share expression patterns with RNU1-58P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU1-58P Gene

Orthologs for RNU1-58P Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU1-58P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 34
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia U1 34
  • 80 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia U1 34
  • 74 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U1 34
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm23099 34
  • 66 (a)
OneToOne
Species where no ortholog for RNU1-58P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-58P Gene

ENSEMBL:
Gene Tree for RNU1-58P (if available)
TreeFam:
Gene Tree for RNU1-58P (if available)

Paralogs for RNU1-58P Gene

No data available for Paralogs for RNU1-58P Gene

Variants for RNU1-58P Gene

Relevant External Links for RNU1-58P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU1-58P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU1-58P Gene

Disorders for RNU1-58P Gene

No disorders were found for RNU1-58P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU1-58P Gene

Publications for RNU1-58P Gene

  1. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1
  2. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba PS … Laird-Offringa IA (The Journal of biological chemistry 2001) 1
  3. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  4. The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. (PMID: 8797828) Balakin AG … Fournier MJ (Cell 1996) 1
  5. Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. (PMID: 7984237) Oubridge C … Nagai K (Nature 1994) 1

Products for RNU1-58P Gene

Sources for RNU1-58P Gene

Content
Loading form....