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Aliases for RNU1-4 Gene

Subcategory (RNA class) for RNU1-4 Gene

snRNA

Quality Score for this RNA gene is

3

Aliases for RNU1-4 Gene

  • RNA, U1 Small Nuclear 4 2 3
  • RNA, U1E2 Small Nuclear 2 3
  • RNA, U1G2 Small Nuclear 2 3
  • RNA, U1D2 Small Nuclear 2 3
  • RNA, U1F1 Small Nuclear 2 3
  • RNA, U1G1 Small Nuclear 2 3
  • RNU1 3 6
  • RNU1D2 3
  • RNU1E2 3
  • RNU1F1 3
  • RNU1G1 3
  • RNU1G2 3
  • RNU1A 6
  • HSD2 3
  • HSD5 3
  • HSD6 3
  • HSD7 3
  • U1B2 3
  • U1D2 3
  • U1E2 3
  • U1F 3

External Ids for RNU1-4 Gene

ORGUL Members for RNU1-4 Gene

Previous HGNC Symbols for RNU1-4 Gene

  • RNU1E2
  • RNU1G2
  • RNU1D2
  • RNU1F1
  • RNU1G1

Previous GeneCards Identifiers for RNU1-4 Gene

  • GC01U902384
  • GC01P017068
  • GC01P015467
  • GC01P017069
  • GC01P017074
  • GC01P017085
  • GC01P017097
  • GC01P017105

Summaries for RNU1-4 Gene

GeneCards Summary for RNU1-4 Gene

RNU1-4 (RNA, U1 Small Nuclear 4) is an RNA Gene, and is affiliated with the snRNA class. Among its related pathways are Spliceosomal Splicing Cycle.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU1-4 Gene

Genomics for RNU1-4 Gene

Genomic Location for RNU1-4 Gene

Start:
16,740,516 bp from pter
End:
16,740,679 bp from pter
Size:
164 bases
Orientation:
Plus strand

Genomic View for RNU1-4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNU1-4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-4 Gene

No data available for Regulatory Elements for RNU1-4 Gene

Proteins for RNU1-4 Gene

Post-translational modifications for RNU1-4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-4 Gene

Domains for RNU1-4 Gene

Gene Families for RNU1-4 Gene

HGNC:
  • snRNA :ncRNAs / Small nuclear RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNU1-4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-4 Gene

Function for RNU1-4 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RNU1-4 Gene

Localization for RNU1-4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU1-4 Gene

Pathways for RNU1-4 Gene

SuperPathways for RNU1-4 Gene

Superpath Contained pathways
1 Spliceosomal Splicing Cycle
genes like me logo Genes that share pathways with RNU1-4: view

Pathways by source for RNU1-4 Gene

1 Qiagen pathway for RNU1-4 Gene

Interacting Proteins for RNU1-4 Gene

Gene Ontology (GO) - Biological Process for RNU1-4 Gene

None

Transcripts for RNU1-4 Gene

mRNA/cDNA for RNU1-4 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNU1-4

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-4 Gene

No ASD Table

Relevant External Links for RNU1-4 Gene

GeneLoc Exon Structure for
RNU1-4
ECgene alternative splicing isoforms for
RNU1-4

Expression for RNU1-4 Gene

mRNA expression in normal human tissues for RNU1-4 Gene

genes like me logo Genes that share expressions with RNU1-4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for RNU1-4 Gene

Orthologs for RNU1-4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU1-4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U1 36
  • 99 (a)
OneToMany
U1 36
  • 99 (a)
OneToMany
dog
(Canis familiaris)
Mammalia U1 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rnu1a1 16
Species with no ortholog for RNU1-4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-4 Gene

ENSEMBL:
Gene Tree for RNU1-4 (if available)
TreeFam:
Gene Tree for RNU1-4 (if available)

Paralogs for RNU1-4 Gene

No data available for Paralogs for RNU1-4 Gene

Variants for RNU1-4 Gene

Sequence variations from dbSNP and Humsavar for RNU1-4 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1746708 -- 16,739,176(+) ggaat(A/G)ttcac upstream-variant-2KB
rs2257983 -- 16,740,731(-) AATAC(A/G)AAAAA downstream-variant-500B
rs2419194 -- 16,740,741(+) TGGTT(G/T)GTGTC downstream-variant-500B
rs2419196 -- 16,740,783(+) GAATA(A/G)GAAGT downstream-variant-500B
rs2900834 -- 16,740,722(+) GTCAT(A/G)TCTTT downstream-variant-500B

Relevant External Links for RNU1-4 Gene

HapMap Linkage Disequilibrium report
RNU1-4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RNU1-4 Gene

Disorders for RNU1-4 Gene

No disorders were found for RNU1-4 Gene.

No data available for UniProtKB/Swiss-Prot for RNU1-4 Gene

Publications for RNU1-4 Gene

  1. Human U1 loci: genes for human U1 RNA have dramatically similar genomic environments. (PMID: 6179629) Manser T. … Gesteland R.F. (Cell 1982) 2 3
  2. Characterization of small nuclear RNA U1 gene candidates and pseudogenes from the human genome. (PMID: 6180116) Manser T. … Gesteland R.F. (J. Mol. Appl. Genet. 1981) 3
  3. True genes for human U1 small nuclear RNA. Copy number, polymorphism, and methylation. (PMID: 6198328) Lund E. … Dahlberg J.E. (J. Biol. Chem. 1984) 3
  4. Analysis of inhibitory action of modified U1 snRNAs on target gene expression: discrimination of two RNA targets differing by a 1 bp mismatch. (PMID: 12034819) Liu P. … Rowe D. (Nucleic Acids Res. 2002) 3
  5. Complex role of the beta 2-beta 3 loop in the interaction of U1A with U1 hairpin II RNA. (PMID: 12082087) Katsamba P.S. … Laird-Offringa I.A. (J. Biol. Chem. 2002) 3

Products for RNU1-4 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate RNU1-4
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RNU1-4
    • Block miRNA regulation of RNU1-4 using miScript Target Protectors

    Sources for RNU1-4 Gene

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