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Aliases for RNU1-32P Gene

Subcategory (RNA class) for RNU1-32P Gene

snRNA

Aliases for RNU1-32P Gene

  • RNA, U1 Small Nuclear 32, Pseudogene 2 3 5

External Ids for RNU1-32P Gene

ORGUL Members for RNU1-32P Gene

Previous GeneCards Identifiers for RNU1-32P Gene

  • GC02P060612
  • GC00U935142

Summaries for RNU1-32P Gene

GeneCards Summary for RNU1-32P Gene

RNU1-32P (RNA, U1 Small Nuclear 32, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU1-32P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU1-32P Gene

Genomics for RNU1-32P Gene

Regulatory Elements for RNU1-32P Gene

Enhancers for RNU1-32P Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F060408 0.5 Ensembl 12.5 +24.6 24596 0.8 RNF2 RNU1-32P ENSG00000233953 GC02M060320 LOC102724142
GH02F060409 1 Ensembl ENCODE 12.5 +27.9 27896 5.4 CTCF BACH1 EBF1 ZIC2 RAD21 RELA ZNF316 ETV6 NFE2 MAFK MIR4432HG RNU1-32P ENSG00000233953 BCL11A GC02M060320 LOC102724142
GH02F060348 1.3 Ensembl ENCODE 12.4 -31.5 -31525 9.1 ELF3 RAD21 ZNF48 ZNF335 SCRT2 ZNF143 ZNF207 THAP11 ZNF654 ZNF680 RNU1-32P MIR4432HG LOC105374756 BCL11A LOC339803 GC02P060372
GH02F060415 1.1 FANTOM5 Ensembl ENCODE 12.4 +31.9 31896 1.4 ZBTB40 MIR4432HG RNU1-32P ENSG00000233953 REL BCL11A GC02M060320
GH02F060405 0.2 Ensembl 12.2 +22.0 21996 2.4 INSM2 KLF17 FEZF1 ZNF2 ZNF121 SCRT2 ZNF391 FOS EGR2 OVOL3 RNU1-32P LOC102724142 GC02M060320
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RNU1-32P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU1-32P Gene

Chromosome:
2
Start:
60,384,605 bp from pter
End:
60,384,763 bp from pter
Size:
159 bases
Orientation:
Plus strand

Genomic View for RNU1-32P Gene

Genes around RNU1-32P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU1-32P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU1-32P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-32P Gene

ORGUL Member Location for RNU1-32P Gene

ORGUL Member Location for RNU1-32P gene

Proteins for RNU1-32P Gene

Post-translational modifications for RNU1-32P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-32P Gene

Domains & Families for RNU1-32P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-32P Gene

Function for RNU1-32P Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-32P Gene

Localization for RNU1-32P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU1-32P Gene

Pathways & Interactions for RNU1-32P Gene

SuperPathways for RNU1-32P Gene

No Data Available

Interacting Proteins for RNU1-32P Gene

Gene Ontology (GO) - Biological Process for RNU1-32P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU1-32P Gene

Transcripts for RNU1-32P Gene

mRNA/cDNA for RNU1-32P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-32P Gene

No ASD Table

Relevant External Links for RNU1-32P Gene

GeneLoc Exon Structure for
RNU1-32P
ECgene alternative splicing isoforms for
RNU1-32P

Expression for RNU1-32P Gene

mRNA expression in normal human tissues for RNU1-32P Gene

genes like me logo Genes that share expression patterns with RNU1-32P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNU1-32P Gene

Orthologs for RNU1-32P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU1-32P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 35
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm22866 35
  • 76 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia U1 35
  • 70 (a)
OneToOne
Species where no ortholog for RNU1-32P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-32P Gene

ENSEMBL:
Gene Tree for RNU1-32P (if available)
TreeFam:
Gene Tree for RNU1-32P (if available)

Paralogs for RNU1-32P Gene

No data available for Paralogs for RNU1-32P Gene

Variants for RNU1-32P Gene

Relevant External Links for RNU1-32P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU1-32P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU1-32P Gene

Disorders for RNU1-32P Gene

No disorders were found for RNU1-32P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU1-32P Gene

Publications for RNU1-32P Gene

  1. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba P.S. … Laird-Offringa I.A. (J. Biol. Chem. 2001) 1
  2. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1
  3. Crystal structure at 1.92-A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. (PMID: 7984237) Oubridge C. … Nagai K. (Nature 1994) 1
  4. Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains. (PMID: 2405391) Kretzner L. … Rosbash M. (Proc. Natl. Acad. Sci. U.S.A. 1990) 1

Products for RNU1-32P Gene

Sources for RNU1-32P Gene

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