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Aliasesfor RNU1-2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Subcategory (RNA class): snRNAQuality score for this RNA gene is 5 Aliases RNA, U1 Small Nuclear 2 1 2 U1C211 2 RNU1C11 2 RNA, U1C1 Small Nuclear1 RNU1C21 2 RNA, U1C2 Small Nuclear1 U1C11 2
External Ids: HGNC: 10123 1 Entrez Gene: 26870 2 Ensembl: ENSG00000207005 7 Export aliases for RNU1-2 gene to outside databases Previous GC identifer: GC01U902390
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Summariesfor RNU1-2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section fRNAdb sequence ontology for RNU1-2: U1_snRNA - U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.View fRNAdb secondary structures for RNU1-2
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Genomic Viewsfor RNU1-2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for RNU1-2 Other transcription factors Search SABiosciences Chromatin IP Primers for RNU1-2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNU1-2
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1p36.1 Ensembl cytogenetic band: 1p36.13 HGNC cytogenetic band: 1p36.13 RNU1-2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P017224: view genomic region
(about GC identifiers )
Start: 17,222,475 bp from pter End:
17,222,638 bp from pter
Size: 164 bases Orientation:
plus strand
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Proteinsfor RNU1-2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --
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Protein
Domains /for RNU1-2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
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Functionfor RNU1-2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models: Cell Line GenScript Custom overexpressing Cell Line Services for RNU1-2 Search LifeMap BioReagents cell lines for RNU1-2
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Pathways & Interactionsfor RNU1-2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 Spliceosomal Splicing Cycle
1 Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNU1-2
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Drugs & Compoundsfor RNU1-2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for RNU1-2 RNU1-2
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Transcriptsfor RNU1-2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 5/6 fRNAdb Secondary structures (see all 6 ): 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000384278(snRNA) GeneLoc Exon Structure
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Expression for RNU1-2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section Expression evidence for RNU1-2:none
RNU1-2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image SABiosciences Custom PCR Arrays for RNU1-2
Primer Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat RNU1-2 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNU1-2 QIAGEN QuantiFast Probe-based Assays in human mouse rat
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Orthologsfor RNU1-2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
ENSEMBL Gene Tree for RNU1-2 (if available)TreeFam Gene Tree for RNU1-2 (if available)
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Paralogsfor RNU1-2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for RNU1-2 gene RNU1-5 2 RNU1-16P 2 ENSG00000207322 2 ENSG00000200885 2 ENSG00000252135 2 ENSG00000202496 2 ENSG00000238554 2 ENSG00000212456 2 ENSG00000206791 2 RNU1-12P 2 ENSG00000201616 2 ENSG00000201170 2 ENSG00000201142 2 ENSG00000200731 2 ENSG00000202167 2 ENSG00000206835 2 ENSG00000200338 2 ENSG00000202077 2 ENSG00000207182 2 RNU1-17P 2 ENSG00000206917 2 ENSG00000201699 2 ENSG00000200807 2 ENSG00000207501 2 ENSG00000212605 2 ENSG00000252491 2 ENSG00000251916 2 ENSG00000201976 2 ENSG00000252625 2 ENSG00000206629 2 ENSG00000202125 2 ENSG00000238833 2 RNU1-15P 2 ENSG00000199773 2 RNU1-19P 2 ENSG00000207205 2 ENSG00000207110 2 ENSG00000206687 2 ENSG00000201922 2 ENSG00000199652 2 ENSG00000199836 2 ENSG00000238898 2 RNU1-20P 2 ENSG00000202408 2 RNU1-6 2 RNU1-14P 2 ENSG00000252209 2 ENSG00000252166 2 ENSG00000206968 2 ENSG00000199361 2 ENSG00000212473 2 ENSG00000212153 2 ENSG00000207340 2 ENSG00000199805 2 ENSG00000202000 2 ENSG00000199846 2 ENSG00000201271 2 RNU1-13P 2 ENSG00000212609 2 ENSG00000202313 2 ENSG00000200903 2 ENSG00000199879 2 ENSG00000239023 2 ENSG00000252925 2 RNU1-9 2 ENSG00000199283 2 ENSG00000202317 2 RNU1-3 2 ENSG00000201119 2 ENSG00000201558 2 RNU1-8 2 ENSG00000252842 2 ENSG00000252099 2 ENSG00000252681 2 ENSG00000194647 2 RNU1-4 2 ENSG00000206908 2 ENSG00000201574 2 ENSG00000200340 2 ENSG00000251970 2 ENSG00000207154 2 ENSG00000239194 2 ENSG00000200296 2 ENSG00000200789 2 ENSG00000212172 2 ENSG00000252311 2 ENSG00000251917 2 RNU1-18P 2 ENSG00000253000 2 ENSG00000202215 2 ENSG00000206698 2 RNU1-1 2 ENSG00000212544 2 ENSG00000200745 2 ENSG00000199497 2 ENSG00000201291 2 ENSG00000200997 2 ENSG00000207106 2 ENSG00000207175 2 ENSG00000199469 2 ENSG00000207220 2 ENSG00000200597 2 ENSG00000207349 2 ENSG00000212424 2 RNU1-7 2 ENSG00000252513 2 ENSG00000201105 2 ENSG00000199687 2 ENSG00000206820 2 ENSG00000202199 2 ENSG00000252990 2 ENSG00000206828 2 ENSG00000201183 2 ENSG00000201910 2 ENSG00000253089 2 ENSG00000199554 2 ENSG00000207056 2 ENSG00000252426 2 RNU1-22P 2 ENSG00000252105 2 ENSG00000199488 2 ENSG00000212550 2 ENSG00000212170 2 ENSG00000194297 2 RNU1-21P 2 ENSG00000252826 2 RNU1-23P 2 ENSG00000207339 2 ENSG00000201493 2 ENSG00000238421 2 ENSG00000200800 2 ENSG00000207201 2 ENSG00000201737 2 ENSG00000201033 2 ENSG00000206624 2 ENSG00000252850 2 ENSG00000202380 2 RNU1-10P 2 ENSG00000206694 2 RNU1-24P 2 ENSG00000252561 2 RNU1-11P 2 ENSG00000200975 2 ENSG00000199426 2 About GeneDecksing
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Genomic Variantsfor RNU1-2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 1 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for RNU1-2 (17222475 - 17222638 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for RNU1-2: --
SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor RNU1-2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
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Publicationsfor RNU1-2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for RNU1-2 gene integrated from 9 sources :(articles sorted by number of sources associating them with RNU1-2) Utopia : connect your pdf to the dynamic
Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transposition. (PubMed id 3837185) 1 , 3(1985) (PubMed id 9016512) 10 (PubMed id 2405391) 10 (PubMed id 7984237) 10 (PubMed id 11297556) 10 (PubMed id 8797828) 10 (PubMed id 2977088) 10 (PubMed id 15608158) 10
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External Searches for RNU1-2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing RNU1-2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing RNU1-2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing RNU1-2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for RNU1-2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for RNU1-2 gene: RNU1-2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor RNU1-2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNU1-2 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNU1-2 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNU1-2 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNU1-2
Search Tocris compounds for RNU1-2
Search ThermoFisher Antibodies for RNU1-2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RNU1-2
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