Aliases for RNU1-2 Gene
Subcategory (RNA class) for RNU1-2 Gene
snRNA
Quality Score for this RNA gene is
3
Aliases for RNU1-2 Gene
External Ids for RNU1-2 Gene
- HGNC: 10123
- Entrez Gene: 26870
- Ensembl: ENSG00000207005
Previous HGNC Symbols for RNU1-2 Gene
- RNU1C1
- RNU1C2
Previous GeneCards Identifiers for RNU1-2 Gene
- GC01U902390
- GC01P017224
- GC01P017227
- GC01P017233
Summaries for RNU1-2 Gene
GeneCards Summary for RNU1-2 Gene
RNU1-2 (RNA, U1 Small Nuclear 2) is an RNA Gene, and is affiliated with the snRNA class. Among its related pathways are Spliceosomal Splicing Cycle.
Additional gene information for RNU1-2 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU1-2 Gene
Genomics for RNU1-2 Gene
GeneHancer (GH) Regulatory Elements for RNU1-2 Gene
Promoters and enhancers for RNU1-2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH01I016894 | Promoter/Enhancer | 1.8 | Ensembl ENCODE dbSUPER | 550.8 | +0.2 | 205 | 2.8 | HDGF PKNOX1 CLOCK SMAD1 ARNT ZFP64 ARID4B SIN3A FEZF1 YY1 | RNU1-2 ZBTB17 ARHGEF19 NECAP2 RPL22P3 SZRD1 MFAP2 RCC2 ENSG00000235241 LOC105376805 | |
| GH01I016891 | Enhancer | 0.7 | dbSUPER | 0.8 | -3.4 | -3372 | 1.9 | PYGO2 ZNF766 CAVIN1 ZNF740 E2F5 NR4A1 CEBPB TEAD2 ZNF354B GTF2A2 | CROCC RPL22P3 MFAP2 RNU1-2 PIR53257 GC01M016886 | |
| GH01I016890 | Enhancer | 0.8 | dbSUPER | 0.4 | -5.1 | -5060 | 1.3 | HDAC1 PKNOX1 ATF1 ARNT TCF12 ZNF766 E2F8 ATF7 CEBPB NCOA1 | ENSG00000235241 GC01P016923 LOC105376805 PIR53257 TRN-GTT4-1 MST1P2 RNU1-2 GC01M016886 CROCC | |
| GH01I016900 | Enhancer | 0.4 | ENCODE | 0.4 | +5.0 | 5011 | 0 | CTCF SMC3 RAD21 | ENSG00000272426 RNU1-2 GC01M016886 CROCC |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around RNU1-2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for RNU1-2 Gene
Genomic Locations for RNU1-2 Gene
- chr1:16,895,980-16,896,143
- (GRCh38/hg38)
- Size:
- 164 bases
- Orientation:
- Plus strand
- chr1:17,222,475-17,222,638
- (GRCh37/hg19)
Genomic View for RNU1-2 Gene
Genes around RNU1-2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.13 by Ensembl
- 1p36.13 by Entrez Gene
- 1p36.13 by HGNC
RNU1-2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNU1-2 Gene
Proteins for RNU1-2 Gene
Post-translational modifications for RNU1-2 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for RNU1-2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RNU1-2
- Origene Custom Protein Services for RNU1-2
- Search GeneTex for Proteins for RNU1-2
No data available for DME Specific Peptides for RNU1-2 Gene
Domains & Families for RNU1-2 Gene
Gene Families for RNU1-2 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-2 Gene
Function for RNU1-2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNU1-2
-
- Search ViGene Biosciences for RNU1-2
CRISPR Products
- Browse CRISPR knockouts for RNU1-2
- Applied Biological Materials CRISPR for RNU1-2
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for RNU1-2
Inhibitory RNA Products
- Search ViGene Biosciences for RNU1-2
Clone Products
- GenScript: Custom all cDNA clones Services for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RNU1-2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-2 Gene
Localization for RNU1-2 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU1-2 Gene
Pathways & Interactions for RNU1-2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Spliceosomal Splicing Cycle | ||
Pathways by source for RNU1-2 Gene
1 Qiagen pathway for RNU1-2 Gene
Interacting Proteins for RNU1-2 Gene
No data available for SIGNOR curated interactions for RNU1-2 Gene
Transcripts for RNU1-2 Gene
mRNA/cDNA for RNU1-2 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for RNU1-2
- Applied Biological Materials CRISPR for RNU1-2
-
Vectors and viruses for KO, Activation, Repression, and more
miRNA Products
- Search ViGene Biosciences for RNU1-2
Inhibitory RNA Products
- Search ViGene Biosciences for RNU1-2
Clone Products
- GenScript: Custom all cDNA clones Services for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for RNU1-2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for RNU1-2 Gene
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU1-2 Gene
Orthologs for RNU1-2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | U1 34 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | U1 34 |
|
OneToMany | |
| chimpanzee (Pan troglodytes) |
Mammalia | U1 34 |
|
OneToOne |
- Species where no ortholog for RNU1-2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for RNU1-2 Gene
No data available for Paralogs for RNU1-2 Gene
Variants for RNU1-2 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1004828127 | -- | 16,894,799(+) | G/A | upstream_transcript_variant | |
| rs1014986397 | -- | 16,894,807(+) | C/T | upstream_transcript_variant | |
| rs10157942 | -- | 16,896,254(+) | C/A/G/T | downstream_transcript_variant | |
| rs10158905 | -- | 16,895,912(+) | G/A/C | upstream_transcript_variant | |
| rs10158908 | -- | 16,895,967(+) | G/A/T | upstream_transcript_variant |
Additional Variant Information for RNU1-2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RNU1-2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU1-2 Gene
Disorders for RNU1-2 Gene
Additional Disease Information for RNU1-2
No disorders were found for RNU1-2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU1-2 Gene
Publications for RNU1-2 Gene
- Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transposition. (PMID: 3837185) Bernstein LB … Weiner AM (Molecular and cellular biology 1985) 2 3 58
- RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3
Products for RNU1-2 Gene
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- Browse cDNA clones at Cloud-Clone Corp.
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- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for RNU1-2
- Search GeneTex for Proteins for RNU1-2
Sources for RNU1-2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew