Aliases for RNU1-2 Gene
Subcategory (RNA class) for RNU1-2 Gene
snRNA
Quality Score for this RNA gene is
3
Aliases for RNU1-2 Gene
External Ids for RNU1-2 Gene
- HGNC: 10123
- Entrez Gene: 26870
- Ensembl: ENSG00000207005
Previous HGNC Symbols for RNU1-2 Gene
- RNU1C1
- RNU1C2
Previous GeneCards Identifiers for RNU1-2 Gene
- GC01U902390
- GC01P017224
- GC01P017227
- GC01P017233
Summaries for RNU1-2 Gene
GeneCards Summary for RNU1-2 Gene
RNU1-2 (RNA, U1 Small Nuclear 2) is an RNA Gene, and is affiliated with the snRNA class. Among its related pathways are Spliceosomal Splicing Cycle.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU1-2 Gene
Genomics for RNU1-2 Gene
Regulatory Elements for RNU1-2 Gene
Enhancers for RNU1-2 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH01G016894 | 1.4 | ENCODE dbSUPER | 0.7 | +0.2 | 206 | 2.8 | HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B SIN3A FEZF1 YY1 ZNF766 | MFAP2 ZBTB17 RCC2 ENSG00000235241 LOC105376805 RNU1-2 ENSG00000272426 |
| GH01G016891 | 0.8 | dbSUPER | 0.7 | -3.4 | -3373 | 1.9 | PKNOX1 KLF17 BMI1 ZNF766 EGR2 ZNF263 CAVIN1 CEBPB ZNF398 ZNF592 | PIR53257 RNU1-2 |
| GH01G016892 | 0.7 | dbSUPER | 0.7 | -3.5 | -3450 | 0.2 | ZNF263 PKNOX1 NFIA KLF17 ZNF398 PRDM2 NFIC GLIS1 ZNF747 TAF7 | RNU1-2 PIR53257 |
| GH01G016900 | 0.9 | ENCODE | 0.4 | +5.0 | 5011 | 0.0 | ZNF493 ZFP64 RAD21 ZNF354C ZNF680 SP3 ZBTB11 ZNF426 REST TSHZ1 | RPL22P3 LINC01772 FBXO42 EIF1AXP1 SPATA21 MFAP2 ENSG00000272426 RNU1-2 |
| GH01G016890 | 0.9 | dbSUPER | 0.4 | -5.1 | -5061 | 1.3 | HDAC1 PKNOX1 ATF1 TBL1XR1 ARNT TCF12 ZNF766 CEBPB NCOA1 ZEB2 | MST1P2 PIR53257 RNU1-2 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RNU1-2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for RNU1-2 Gene
- Chromosome:
- 1
- Start:
- 16,895,980 bp from pter
- End:
- 16,896,143 bp from pter
- Size:
- 164 bases
- Orientation:
- Plus strand
Genomic View for RNU1-2 Gene
Genes around RNU1-2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p36.13 by Ensembl
- 1p36.13 by Entrez Gene
- 1p36.13 by HGNC
RNU1-2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNU1-2 Gene
Proteins for RNU1-2 Gene
Post-translational modifications for RNU1-2 Gene
No Post-translational modifications
Antibody Products
- Search GeneTex for Antibodies for RNU1-2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RNU1-2
- Origene Custom Protein Services for RNU1-2
- Search GeneTex for Proteins for RNU1-2
Assay Products
No data available for DME Specific Peptides for RNU1-2 Gene
Domains & Families for RNU1-2 Gene
Gene Families for RNU1-2 Gene
- HGNC:
Graphical View of Domain Structure for InterPro Entry
No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-2 Gene
Function for RNU1-2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNU1-2
-
- Search ViGene Biosciences for RNU1-2
CRISPR Products
- Browse CRISPR knockouts for RNU1-2
miRNA Products
- Search ViGene Biosciences for RNU1-2
Inhibitory RNA Products
- Search ViGene Biosciences for RNU1-2
Clone Products
- GenScript: Custom all cDNA clones Services for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
- Search ViGene Biosciences for RNU1-2
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-2 Gene
Localization for RNU1-2 Gene
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU1-2 Gene
Pathways & Interactions for RNU1-2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Spliceosomal Splicing Cycle | ||
Pathways by source for RNU1-2 Gene
1 Qiagen pathway for RNU1-2 Gene
Interacting Proteins for RNU1-2 Gene
No data available for SIGNOR curated interactions for RNU1-2 Gene
Transcripts for RNU1-2 Gene
mRNA/cDNA for RNU1-2 Gene
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for RNU1-2
miRNA Products
- Search ViGene Biosciences for RNU1-2
Inhibitory RNA Products
- Search ViGene Biosciences for RNU1-2
Clone Products
- GenScript: Custom all cDNA clones Services for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for RNU1-2 Gene
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU1-2 Gene
Orthologs for RNU1-2 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | U1 35 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | U1 35 |
|
OneToMany | |
| chimpanzee (Pan troglodytes) |
Mammalia | U1 35 |
|
OneToOne |
- Species where no ortholog for RNU1-2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for RNU1-2 Gene
No data available for Paralogs for RNU1-2 Gene
Variants for RNU1-2 Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1004828127 | -- | 16,894,799(+) | GCCTA(A/G)GTAAA | upstream-variant-2KB | |
| rs1014986397 | -- | 16,894,807(+) | AAAAC(C/T)TCCGT | upstream-variant-2KB | |
| rs10157942 | -- | 16,896,254(+) | GCTGG(C/G)GAATA | downstream-variant-500B | |
| rs10158905 | -- | 16,895,912(+) | GCGCG(A/G)GGCAA | upstream-variant-2KB | |
| rs10158908 | -- | 16,895,967(+) | GCAGA(A/G)CCCGA | upstream-variant-2KB |
Relevant External Links for RNU1-2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RNU1-2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNU1-2 Gene
Disorders for RNU1-2 Gene
No disorders were found for RNU1-2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU1-2 Gene
Publications for RNU1-2 Gene
- Human U1 small nuclear RNA genes: extensive conservation of flanking sequences suggests cycles of gene amplification and transposition. (PMID: 3837185) Bernstein L.B. … Weiner A.M. (Mol. Cell. Biol. 1985) 2 3 64
Products for RNU1-2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
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- Browse Immunoprecipitation Assays
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RNU1-2
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- Browse OriGene qPCR primer pairs and template standards
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Custom all cDNA clones Services for RNU1-2
- GenScript Custom Purified and Recombinant Proteins Services for RNU1-2
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- Browse GenScript CRISPR for RNU1-2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNU1-2
- VectorBuilder custom plasmid, inducible vectors for RNU1-2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNU1-2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RNU1-2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer