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Aliases for RNU1-15P Gene

Subcategory (RNA class) for RNU1-15P Gene

snRNA

Aliases for RNU1-15P Gene

  • RNA, U1 Small Nuclear 15, Pseudogene 2 3 5
  • RNA, U1 Small Nuclear Pseudogene 8 2 3
  • RNU1P8 3
  • U1P11 3

External Ids for RNU1-15P Gene

Previous HGNC Symbols for RNU1-15P Gene

  • RNU1P8

Summaries for RNU1-15P Gene

GeneCards Summary for RNU1-15P Gene

RNU1-15P (RNA, U1 Small Nuclear 15, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU1-15P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

View fRNAdb secondary structures for RNU1-15P

Additional gene information for RNU1-15P Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU1-15P Gene

Genomics for RNU1-15P Gene

GeneHancer (GH) Regulatory Elements for RNU1-15P Gene

Promoters and enhancers for RNU1-15P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I021352 Enhancer 1.4 FANTOM5 Ensembl ENCODE 0.3 -26.9 -26916 4.9 HDGF PKNOX1 SMAD1 IRF4 GATA2 ATF7 RUNX3 JUNB SMARCA4 NBN SP4 GC07M021324 RNU1-15P
GH07I021383 Enhancer 0.4 ENCODE 0.8 +2.2 2215 0.2 CEBPG DPF2 RNU1-15P GC07P021392
GH07I021365 Enhancer 0.8 ENCODE 0.4 -14.9 -14888 1 ELF3 FOXA2 INSM2 FEZF1 RARA ZNF366 FOS ATF7 CEBPB TSHZ1 SP4 RNU1-15P GC07M021324
GH07I021358 Enhancer 0.7 Ensembl ENCODE 0.3 -22.5 -22515 0.9 FOXA2 BCL6B CEBPA CEBPB ZNF24 SPI1 SP4 GC07M021324 RNU1-15P
GH07I021357 Enhancer 0.5 Ensembl 0.3 -24.0 -23962 0.4 ZNF316 CEBPB EMSY MGA SP4 GC07M021324 RNU1-15P
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RNU1-15P on UCSC Golden Path with GeneCards custom track

Genomic Locations for RNU1-15P Gene

Genomic Locations for RNU1-15P Gene
chr7:21,381,363-21,381,506
(GRCh38/hg38)
Size:
144 bases
Orientation:
Plus strand
chr7:21,420,981-21,421,124
(GRCh37/hg19)

Genomic View for RNU1-15P Gene

Genes around RNU1-15P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU1-15P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU1-15P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-15P Gene

ORGUL Member Location for RNU1-15P Gene

ORGUL Member Location for RNU1-15P gene

Proteins for RNU1-15P Gene

Post-translational modifications for RNU1-15P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-15P Gene

Domains & Families for RNU1-15P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-15P Gene

Function for RNU1-15P Gene

Phenotypes From GWAS Catalog for RNU1-15P Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-15P Gene

Localization for RNU1-15P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNU1-15P Gene

Pathways & Interactions for RNU1-15P Gene

SuperPathways for RNU1-15P Gene

No Data Available

Interacting Proteins for RNU1-15P Gene

Gene Ontology (GO) - Biological Process for RNU1-15P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU1-15P Gene

Drugs & Compounds for RNU1-15P Gene

No Compound Related Data Available

Transcripts for RNU1-15P Gene

fRNAdb Secondary structures for RNU1-15P Gene

  • RF00003;U1;DAAB012141556.1/904-798

mRNA/cDNA for RNU1-15P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-15P Gene

No ASD Table

Relevant External Links for RNU1-15P Gene

GeneLoc Exon Structure for
RNU1-15P
ECgene alternative splicing isoforms for
RNU1-15P

Expression for RNU1-15P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNU1-15P Gene

genes like me logo Genes that share expression patterns with RNU1-15P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNU1-15P Gene

Orthologs for RNU1-15P Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU1-15P Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 34
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U1 34
  • 65 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U1 34
  • 62 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia U1 34
  • 57 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm22211 34
  • 56 (a)
ManyToMany
Species where no ortholog for RNU1-15P was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-15P Gene

ENSEMBL:
Gene Tree for RNU1-15P (if available)
TreeFam:
Gene Tree for RNU1-15P (if available)

Paralogs for RNU1-15P Gene

No data available for Paralogs for RNU1-15P Gene

Variants for RNU1-15P Gene

Additional Variant Information for RNU1-15P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNU1-15P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNU1-15P Gene

Disorders for RNU1-15P Gene

Additional Disease Information for RNU1-15P

Genetic Association Database
(GAD)

No disorders were found for RNU1-15P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNU1-15P Gene

Publications for RNU1-15P Gene

  1. Human U1 RNA pseudogenes may be generated by both DNA- and RNA-mediated mechanisms. (PMID: 6085956) Denison RA … Weiner AM (Molecular and cellular biology 1982) 2 3 58
  2. NONCODE: an integrated knowledge database of non-coding RNAs. (PMID: 15608158) Liu C … Chen R (Nucleic acids research 2005) 1
  3. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba PS … Laird-Offringa IA (The Journal of biological chemistry 2001) 1
  4. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  5. The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions. (PMID: 8797828) Balakin AG … Fournier MJ (Cell 1996) 1

Products for RNU1-15P Gene

Sources for RNU1-15P Gene

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