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Aliases for RNU1-119P Gene

Subcategory (RNA class) for RNU1-119P Gene

snRNA

Aliases for RNU1-119P Gene

  • RNA, U1 Small Nuclear 119, Pseudogene 2 3 5

External Ids for RNU1-119P Gene

ORGUL Members for RNU1-119P Gene

Previous GeneCards Identifiers for RNU1-119P Gene

  • GC15P045178
  • GC00U935857

Summaries for RNU1-119P Gene

GeneCards Summary for RNU1-119P Gene

RNU1-119P (RNA, U1 Small Nuclear 119, Pseudogene) is a Pseudogene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for RNU1-119P Gene - the ORGUL cluster for this gene includes several descriptions:

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

  • U1 spliceosomal RNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV [1]. This family does not contain the larger yeast sequences.

View fRNAdb secondary structures for RNU1-119P

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for RNU1-119P Gene

Genomics for RNU1-119P Gene

Regulatory Elements for RNU1-119P Gene

Enhancers for RNU1-119P Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNU1-119P on UCSC Golden Path with GeneCards custom track

Genomic Location for RNU1-119P Gene

Chromosome:
15
Start:
44,884,616 bp from pter
End:
44,884,780 bp from pter
Size:
165 bases
Orientation:
Plus strand

Genomic View for RNU1-119P Gene

Genes around RNU1-119P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNU1-119P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNU1-119P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for RNU1-119P Gene

ORGUL Member Location for RNU1-119P gene

No data available for RefSeq DNA sequence for RNU1-119P Gene

Proteins for RNU1-119P Gene

Post-translational modifications for RNU1-119P Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-119P Gene

Domains & Families for RNU1-119P Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNU1-119P Gene

Function for RNU1-119P Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNU1-119P Gene

Localization for RNU1-119P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for RNU1-119P Gene

Pathways & Interactions for RNU1-119P Gene

SuperPathways for RNU1-119P Gene

No Data Available

Interacting Proteins for RNU1-119P Gene

Gene Ontology (GO) - Biological Process for RNU1-119P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNU1-119P Gene

Drugs & Compounds for RNU1-119P Gene

No Compound Related Data Available

Transcripts for RNU1-119P Gene

fRNAdb Secondary structures for RNU1-119P Gene

  • RF00003;U1;ADDF014515869.1/91-1

mRNA/cDNA for RNU1-119P Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-119P Gene

No ASD Table

Relevant External Links for RNU1-119P Gene

GeneLoc Exon Structure for
RNU1-119P
ECgene alternative splicing isoforms for
RNU1-119P

Expression for RNU1-119P Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for RNU1-119P Gene

Orthologs for RNU1-119P Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNU1-119P Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia U1 36
  • 71 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Gm23376 36
  • 74 (a)
ManyToMany
Gm24145 36
  • 77 (a)
ManyToMany
Gm25630 36
  • 71 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia U1 36
  • 75 (a)
ManyToMany
U1 36
  • 86 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia U1 36
  • 97 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia U1 36
  • 75 (a)
ManyToMany
Species with no ortholog for RNU1-119P:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-119P Gene

ENSEMBL:
Gene Tree for RNU1-119P (if available)
TreeFam:
Gene Tree for RNU1-119P (if available)

Paralogs for RNU1-119P Gene

No data available for Paralogs for RNU1-119P Gene

Variants for RNU1-119P Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for RNU1-119P Gene

Disorders for RNU1-119P Gene

No disorders were found for RNU1-119P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNU1-119P Gene

Publications for RNU1-119P Gene

  1. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba P.S. … Laird-Offringa I.A. (J. Biol. Chem. 2001) 1
  2. The uRNA database. (PMID: 9016512) Zwieb C. (Nucleic Acids Res. 1997) 1
  3. Crystal structure at 1.92-A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. (PMID: 7984237) Oubridge C. … Nagai K. (Nature 1994) 1
  4. Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains. (PMID: 2405391) Kretzner L. … Rosbash M. (Proc. Natl. Acad. Sci. U.S.A. 1990) 1

Products for RNU1-119P Gene

Sources for RNU1-119P Gene

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