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Aliases for RNU1-1 Gene

Subcategory (RNA class) for RNU1-1 Gene

snRNA

Quality Score for this RNA gene is

13

Aliases for RNU1-1 Gene

  • RNA, U1 Small Nuclear 1 2 3
  • RNA, U1G4 Small Nuclear 2 3
  • RNA, U1A3 Small Nuclear 2 3
  • RNA, U1A Small Nuclear 2 3
  • Rnu1a1 3
  • RNU1A3 3
  • RNU1G4 3
  • RNU1A 3
  • HU1-1 3
  • RNU1 3
  • HSD1 3
  • U1A1 3
  • U1 3

External Ids for RNU1-1 Gene

ORGUL Members for RNU1-1 Gene

Previous Symbols for RNU1-1 Gene

  • RNU1
  • RNU1G4
  • RNU1A3
  • RNU1A

Summaries for RNU1-1 Gene

GeneCards Summary for RNU1-1 Gene

RNU1-1 (RNA, U1 Small Nuclear 1) is a RNA Gene, and belongs to snRNA RNA class. Among its related pathways are Spliceosomal Splicing Cycle.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNU1-1 Gene

Genomics for RNU1-1 Gene

Genomic Location for RNU1-1 Gene

Start:
16,514,122 bp from pter
End:
16,514,285 bp from pter
Size:
164 bases
Orientation:
Minus strand

Genomic View for RNU1-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNU1-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNU1-1 Gene

No data available for Regulatory Elements for RNU1-1 Gene

Proteins for RNU1-1 Gene

Post-translational modifications for RNU1-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNU1-1 Gene

Domains for RNU1-1 Gene

Gene Families for RNU1-1 Gene

HGNC:
  • snRNA :ncRNAs / Small nuclear RNAs
genes like me logo Genes that share domains with RNU1-1: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for RNU1-1 Gene

Function for RNU1-1 Gene

miRNA for RNU1-1 Gene

miRTarBase miRNAs that target RNU1-1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for RNU1-1 Gene

Localization for RNU1-1 Gene

No data available for Gene Ontology (GO) - Cellular Components for RNU1-1 Gene

Pathways for RNU1-1 Gene

SuperPathways for RNU1-1 Gene

Superpath Contained pathways
1 Spliceosomal Splicing Cycle
genes like me logo Genes that share pathways with RNU1-1: view

Pathways by source for RNU1-1 Gene

1 Qiagen pathway for RNU1-1 Gene

Interacting Proteins for RNU1-1 Gene

Gene Ontology (GO) - Biological Process for RNU1-1 Gene

None

Transcripts for RNU1-1 Gene

mRNA/cDNA for RNU1-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNU1-1 Gene

No ASD Table

Relevant External Links for RNU1-1 Gene

GeneLoc Exon Structure for
RNU1-1
ECgene alternative splicing isoforms for
RNU1-1

Expression for RNU1-1 Gene

mRNA expression in normal human tissues for RNU1-1 Gene

genes like me logo Genes that share expressions with RNU1-1: view

Orthologs for RNU1-1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNU1-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia U1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia U1 37
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia U1 37
  • 100 (a)
ManyToMany
Species with no ortholog for RNU1-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNU1-1 Gene

ENSEMBL:
Gene Tree for RNU1-1 (if available)
TreeFam:
Gene Tree for RNU1-1 (if available)

Paralogs for RNU1-1 Gene

No data available for Paralogs for RNU1-1 Gene

Variants for RNU1-1 Gene

Sequence variations from dbSNP and Humsavar for RNU1-1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs156901 -- 16,513,967(-) AAAAA(A/G)CGAGC downstream-variant-500B
rs156902 -- 16,514,291(+) GAAAC(C/G)TTGTG upstream-variant-2KB
rs157254 -- 16,514,235(-) CCCAG(A/G)GCGAG nc-transcript-variant
rs157255 -- 16,514,460(-) GCTGC(G/T)TCGCC upstream-variant-2KB
rs157256 -- 16,514,605(-) CTTCC(C/T)CTTGG upstream-variant-2KB

Relevant External Links for RNU1-1 Gene

HapMap Linkage Disequilibrium report
RNU1-1

No data available for Structural Variations from Database of Genomic Variants (DGV) for RNU1-1 Gene

Disorders for RNU1-1 Gene

No disorders were found for RNU1-1 Gene.

No data available for UniProtKB/Swiss-Prot for RNU1-1 Gene

Publications for RNU1-1 Gene

  1. Complex role of the beta 2-beta 3 loop in the interaction of U1A with U1 hairpin II RNA. (PMID: 12082087) Katsamba P.S. … Laird-Offringa I.A. (J. Biol. Chem. 2002) 2 3
  2. Composition and three-dimensional EM structure of double affinity- purified, human prespliceosomal A complexes. (PMID: 17332742) Behzadnia N. … Luehrmann R. (EMBO J. 2007) 3
  3. The multifunctional human p100 protein 'hooks' methylated ligands. (PMID: 17632523) Shaw N. … Rao Z. (Nat. Struct. Mol. Biol. 2007) 3
  4. U1 snRNA directly interacts with polypyrimidine tract-binding protein during splicing repression. (PMID: 21362553) Sharma S. … Black D.L. (Mol. Cell 2011) 3
  5. U1 snRNP determines mRNA length and regulates isoform expression. (PMID: 22770214) Berg M.G. … Dreyfuss G. (Cell 2012) 3

Products for RNU1-1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate RNU1-1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RNU1-1
    • Block miRNA regulation of RNU1-1 using miScript Target Protectors

    Sources for RNU1-1 Gene

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