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Aliases for RNR4 Gene

Subcategory (RNA class) for RNR4 Gene

non-coding RNA

Quality Score for this RNA gene is

2

Aliases for RNR4 Gene

  • RNA, Ribosomal 45S Cluster 4 2 3
  • RNA, Ribosomal Cluster 4 2
  • 45S RDNA Cluster 4 2
  • RNA, Ribosomal 4 2

External Ids for RNR4 Gene

Summaries for RNR4 Gene

Entrez Gene Summary for RNR4 Gene

  • 45S ribosomal DNA (rDNA) arrays, or clusters, are present on human chromosomes 13, 14, 15, 21 and 22, designated RNR1 through RNR5, respectively. Each cluster consists of multiple 45S rDNA repeat units that vary in number among individuals and chromosomes, with total diploid copy number estimates ranging from 60 to >800 repeat units in a human genome. The 45S rDNA repeat unit encodes a 45S rRNA precursor, transcribed by RNA polymerase I, which is processed to form the 18S, 5.8S and 28S rRNAs. Gene and RefSeq, in collaboration with HGNC, currently describe one 45S rDNA cluster, and one set of 45S precursor and product rRNAs, for each of the five human chromosomes to which these loci are localized. This gene represents the 45S ribosomal DNA cluster on chromosome 21. [provided by RefSeq, Feb 2017]

GeneCards Summary for RNR4 Gene

RNR4 (RNA, Ribosomal 45S Cluster 4) is an RNA Gene, and is affiliated with the non-coding RNA class. Among its related pathways are Viral mRNA Translation.

Gene Wiki entry for RNR4 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNR4 Gene

Genomics for RNR4 Gene

Genomic Location for RNR4 Gene

Chromosome:
21
Orientation:
Unknown strand

Genomic View for RNR4 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for Regulatory Elements and RefSeq DNA sequence for RNR4 Gene

Proteins for RNR4 Gene

Post-translational modifications for RNR4 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNR4 Gene

Domains & Families for RNR4 Gene

Gene Families for RNR4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNR4: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNR4 Gene

Function for RNR4 Gene

Molecular function for RNR4 Gene

GENATLAS Biochemistry:
RNA,ribosomal cluster 4

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNR4 Gene

Localization for RNR4 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNR4 gene
Compartment Confidence
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RNR4 Gene

Pathways & Interactions for RNR4 Gene

genes like me logo Genes that share pathways with RNR4: view

Pathways by source for RNR4 Gene

1 GeneGo (Thomson Reuters) pathway for RNR4 Gene

Interacting Proteins for RNR4 Gene

Gene Ontology (GO) - Biological Process for RNR4 Gene

None

No data available for SIGNOR curated interactions for RNR4 Gene

Expression for RNR4 Gene

NURSA nuclear receptor signaling pathways regulating expression of RNR4 Gene:

RNR4
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNR4 Gene

Orthologs for RNR4 Gene

No data available for Orthologs and Evolution for RNR4 Gene

Paralogs for RNR4 Gene

No data available for Paralogs for RNR4 Gene

Variants for RNR4 Gene

Relevant External Links for RNR4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNR4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for RNR4 Gene

Disorders for RNR4 Gene

No disorders were found for RNR4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for RNR4 Gene

Publications for RNR4 Gene

  1. The Epigenetic Pathways to Ribosomal DNA Silencing. (PMID: 27250769) Srivastava R. … Ahn S.H. (Microbiol. Mol. Biol. Rev. 2016) 3 64
  2. Nucleolar organizer regions: genomic 'dark matter' requiring illumination. (PMID: 27474438) McStay B. (Genes Dev. 2016) 3 64
  3. A Portrait of Ribosomal DNA Contacts with Hi-C Reveals 5S and 45S rDNA Anchoring Points in the Folded Human Genome. (PMID: 27797956) Yu S. … Lemos B. (Genome Biol Evol 2016) 3 64
  4. An overview of pre-ribosomal RNA processing in eukaryotes. (PMID: 25346433) Henras A.K. … Gleizes P.E. (Wiley Interdiscip Rev RNA 2015) 3 64
  5. Concerted copy number variation balances ribosomal DNA dosage in human and mouse genomes. (PMID: 25583482) Gibbons J.G. … Lemos B. (Proc. Natl. Acad. Sci. U.S.A. 2015) 3 64

Products for RNR4 Gene

Sources for RNR4 Gene

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