RNPS1 Gene
protein-coding GIFtS: 55
GCID: GC16M002303
|
|
RNA binding protein S1, serine-rich domain(Previous names: RNA-binding protein S1, serine-rich domain )
| |
Aliases
for RNPS1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| RNA Binding Protein S1, Serine-Rich Domain1 2 | | RNA-Binding Protein With Serine-Rich Domain 12 | | RNA-Binding Protein S1, Serine-Rich Domain1 2 | | SR Protein2 | | SR-Related Protein LDC22 3 | | LDC23 | | E5.12 | | |
Export aliases for RNPS1 gene to outside databasesPrevious GC identifers: GC16P002468 GC16M002328 GC16M002244 GC16M002245 GC16M002246 GC16M002168 GC16M002247 GC16M002230 |
Summaries
for RNPS1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RNPS1:
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear exportand mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiatesnonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMDto degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclearexport, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Two splicevariants have been found for this gene; both variants encode the same protein. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RNPS1_HUMAN, Q15287Function: Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction onmRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear andcytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequentmRNA metabolism. Part of pre- and post-splicing multiprotein mRNP complexes. Enhances the formation of theATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 andTRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Participates in mRNA3'-end cleavage. Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream ofexon-exon junctions
Gene Wiki entry for RNPS1
|
Genomic Views
for RNPS1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNPS1 gene promoter:
CREB p53 COMP1 deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNPS1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNPS1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3RNPS1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M002303: view genomic region
(about GC identifiers)
Start:
|
2,303,117 bp from pter |
End:
|
2,318,413 bp from pter |
Size:
|
15,297 bases |
Orientation:
|
minus strand |
|
Proteins
for RNPS1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RNPS1_HUMAN, Q15287 (See
protein sequence)Recommended Name: RNA-binding protein with serine-rich domain 1 Size: 305 amino acids; 34208 Da
Subunit: Found in a mRNA splicing-dependent exon junction complex (EJC), at least composed of ACIN1, CASC3, EIF4A3,MAGOH, PNN, RBM8A, RNPS1, SAP18 and ALYREF/THOC4. Forms heterodimers with ACIN1. Found in a heterotrimeric complexwith ACIN1, RNPS1 and SAP18. Component of the active spliceosome. Associates with polysomes. Found in a mRNAsplicing-dependent exon junction complex (EJC) with DEK, RBM8A, RNPS1, SRRM1 and ALYREF/THOC4. Found in apost-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Interacts with the cleaved p110 isoform ofCDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10
Subcellular location: Nucleus. Nucleus speckle. Cytoplasm. Note=Nucleocytoplasmic shuttling protein. Colocalizes withthe core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles
1 PDB 3D structure from  and Proteopedia  for RNPS1:4A8X (3D)
Secondary accessions: A8K1P0 B4DDU8 B4DZU7 B7ZA17 O75308 Q32P25 Q8WY42 Q9NYG3Alternative splicing: 3 isoforms: Q15287-1 Q15287-2 Q15287-3 Explore the universe of human proteins at neXtProt for RNPS1: NX_Q15287
Post-translational modifications:
Phosphorylated on one or more of the four Ser/Thr residues (Ser-43, Thr-49, Ser-52 or Ser-53). Ser-53 phosphorylationsite is important for splicing and translation stimulation activity in vitro1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15287
RNPS1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_006702.1 NP_542161.1
ENSEMBL proteins: ENSP00000380275 ENSP00000315859 ENSP00000456352 ENSP00000455379 ENSP00000457723 ENSP00000455306 ENSP00000457820 ENSP00000457987 ENSP00000301730 ENSP00000454513 ENSP00000457110 ENSP00000456085 ENSP00000454461 ENSP00000455013 ENSP00000457690 ENSP00000457378 ENSP00000457618 ENSP00000457296 ENSP00000455195 ENSP00000454867 ENSP00000457338 ENSP00000456283 Reactome Protein details: Q15287
Human Recombinant Protein Products for RNPS1:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
RNPS1 for ontologies About GeneDecksing
RNPS1 Antibody Products:
Assay Products for RNPS1: |
Protein
Domains /
Families
for RNPS1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNPS1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15287ProtoNet protein and cluster: Q15287 1 Blocks protein family: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
UniProtKB/Swiss-Prot: RNPS1_HUMAN, Q15287Similarity: Belongs to the splicing factor SR familySimilarity: Contains 1 RRM (RNA recognition motif) domain |
Function
for RNPS1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: RNPS1_HUMAN, Q15287Function: Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction onmRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear andcytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequentmRNA metabolism. Part of pre- and post-splicing multiprotein mRNP complexes. Enhances the formation of theATP-dependent A complex of the spliceosome. Involved in both constitutive splicing and, in association with SRP54 andTRA2B/SFRS10, in distinctive modulation of alternative splicing in a substrate-dependent manner. Participates in mRNA3'-end cleavage. Involved in UPF2-dependent nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.Also mediates increase of mRNA abundance and translational efficiency. Binds spliced mRNA 20-25 nt upstream ofexon-exon junctions Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
RNPS1 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for RNPS1:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): RNPS1 (NM_080594) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNPS1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNPS1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNPS1 |
|
Pathways & Interactions
for RNPS1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RNA Polymerase II Transcription Termination | | | 2 | mRNA Splicing - Major Pathway | | | 3 | Synthesis of PB1-F2 | | | 4 | Metabolism of mRNA | | | 5 | Transcription | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for RNPS1
5/20 
Reactome Pathways for RNPS1 (see all 20)
2 
Kegg Pathways (Kegg details for RNPS1):
RNPS1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RNPS1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/298 Interacting proteins for RNPS1 (Q152871, 2, 3 ENSP000003158594) via UniProtKB, MINT, STRING, and/or I2D (see all 298)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| YWHAG | P619812, 3, ENSP000003063304 | MINT-50800 I2D:
score=4 STRING: ENSP00000306330 | | SRPK2 | P783622, 3, ENSP000003772624 | MINT-8337904 I2D:
score=2 STRING: ENSP00000377262 | | SRSF1 | Q079552, 3, ENSP000002589624 | MINT-8335594 I2D:
score=2 STRING: ENSP00000258962 | | SF3A2 | Q154282, 3, ENSP000002214944 | MINT-5206268 I2D:
score=1 STRING: ENSP00000221494 | | SRSF4 | Q081702, 3, ENSP000003629004 | MINT-8337893 I2D:
score=1 STRING: ENSP00000362900 |
About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
TAS | -- | | GO:0000398 | mRNA splicing, via spliceosome |
TAS | -- | | GO:0006351 | transcription, DNA-dependent |
TAS | 9580558 | | GO:0006366 | transcription from RNA polymerase II promoter |
TAS | -- | | GO:0006369 | termination of RNA polymerase II transcription |
TAS | -- |
RNPS1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RNPS1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
RNPS1 for compounds About GeneDecksing
 Browse Tocris compounds for RNPS1
4 Novoseek chemical compound relationships for RNPS1 gene About this table
Search CenterWatch for drugs/clinical trials and news about RNPS1
|
Transcripts
for RNPS1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNPS1 gene (2 alternative transcripts): NM_006711.3 NM_080594.2 Unigene Clusters for RNPS1: RNA binding protein S1, serine-rich domain Hs.355643 [show with all ESTs], Hs.733012 [show with all ESTs]Unigene Representative Sequences: AK092131, AK02179918/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27): ENST00000397086(uc002cpu.3) ENST00000320225(uc002cpw.3 uc002cpx.3 uc010uwa.2)
ENST00000566458 ENST00000562205 ENST00000565243 ENST00000566397 ENST00000565678(uc002cpt.3)
ENST00000561718 ENST00000568631 ENST00000569598 ENST00000301730 ENST00000567147
ENST00000565870 ENST00000564760 ENST00000561518 ENST00000564311 ENST00000570051
ENST00000564601
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): RNPS1 (NM_080594) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNPS1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNPS1 |
Additional cDNA sequence: AK021799.1 24/48 DOTS entries (see all 48): DT.75198118 DT.100881923 DT.97813561 DT.91688578 DT.100045084 DT.100881937 DT.100045088 DT.100881945 DT.100881950 DT.91957712 DT.100881929 DT.100881943 DT.100881936 DT.101985517 DT.91770560 DT.97862610 DT.100881952 DT.120673779 DT.119658 DT.120673740 DT.100881905 DT.100881925 DT.100045085 DT.100768991 24/128 AceView cDNA sequences (see all 128): CR626163 CR593509 AK021799 CR599280 CR593829 AF274003 CR607342 CR623779 CR608607 CR594976 AA836956 CR596728 BC001659 CR612691 AA617951 CR605668 CR591441 CR615513 CR613111 NM_006711 NM_080594 AF247662 AL047568 CR610866
GeneLoc Exon Structure
|
Expression
for RNPS1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNPS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCAGGCAGTC
About this image
See RNPS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNPS1
SOURCE GeneReport for Unigene clusters: Hs.355643 Hs.733012
UniProtKB/Swiss-Prot: RNPS1_HUMAN, Q15287Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for RNPS1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNPS1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RNPS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNPS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNPS1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNPS1 |
Orthologs
for RNPS1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RNPS1 gene from 8/27 species (see all 27) About this table
ENSEMBL Gene Tree for RNPS1 (if available)
TreeFam Gene Tree for RNPS1 (if available) |
Paralogs
for RNPS1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNPS1 gene
- ZCCHC102 PNN2 TPRXL2
6 SIMAP similar genes for RNPS1 using alignment to 17 protein entries: RNPS1_HUMAN (see all proteins):SRSF5 RBMY1A1 PABPC1 SFRS2 RBMX SRSF2
RNPS1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for RNPS1
PGOHUM00000262454
|
Genomic Variants
for RNPS1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RNPS1 (2303117 - 2318413 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RNPS1
2 CNVs: 30002 5329 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNPS1 |
|
Disorders
/ Diseases
for RNPS1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RNPS1 for disorders About GeneDecksing
OMIM gene information: 606447
OMIM disorders: --
15  diseases for RNPS1: About MalaCardsopen-angle glaucoma primary open angle glaucoma dna topoisomerase i tuberous sclerosis, type 2
tuberous sclerosis acinar cell carcinoma systemic lupus erythematosus polycystic kidney disease
lupus erythematosus glaucoma mucoepidermoid carcinoma kidney disease
ataxia carcinoma malaria
1 disease from the University of Copenhagen DISEASES database for RNPS1:Acinar cell carcinoma Export disorders for RNPS1 gene to outside databases
|
Publications
for RNPS1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNPS1 gene, integrated from 9 sources (see all 129):
(articles sorted by number of sources associating them with RNPS1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinases in vivo. (PubMed id 9580558)1, 2, 3 Loyer P.... Kidd V.J. (1998)
- Identification and characterisation of a novel human RNA-binding protein. (PubMed id 8543184)1, 2, 3 Badolato J.... Eisman J. (1995)
- Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation. (PubMed id 15684395)1, 2, 9 Trembley J.H.... Mayeda A. (2005)
- Human RNPS1 and its associated factors: a versatile alternative pre- mRNA splicing regulator in vivo. (PubMed id 14729963)1, 2, 9 Sakashita E.... Mayeda A. (2004)
- Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing. (PubMed id 10449421)1, 2, 9 Mayeda A....Krainer A.R. (1999)
- Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation. (PubMed id 11477570)1, 2, 9 Harada K.... Shichijo S. (2001)
- Nuclear Pnn/DRS protein binds to spliced mRNPs and participates in mRNA processing and export via interaction with RNPS1. (PubMed id 14517304)1, 2, 9 Li C.... Tarn W.-Y. (2003)
- Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1. (PubMed id 11546874)1, 2, 9 Lykke-Andersen J.... Steitz J.A. (2001)
- Splicing enhances translation in mammalian cells: an additional function of the exon junction complex. (PubMed id 14752011)1, 2, 9 Nott A.... Moore M.J. (2004)
- A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex. (PubMed id 14625303)1, 2, 9 Kataoka N. and Dreyfuss G. (2004)
|
External Searches for RNPS1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RNPS1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNPS1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNPS1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNPS1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RNPS1 gene:
Search GeneIP for patents involving RNPS1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RNPS1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RNPS1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNPS1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNPS1 | | | OriGene Protein Over-expression Lysate for RNPS1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RNPS1 | | OriGene 3'-UTR Clone for RNPS1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNPS1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RNPS1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RNPS1 | | OriGene Custom Protein Services for RNPS1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNPS1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNPS1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNPS1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNPS1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNPS1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNPS1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for RNPS1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | RNPS1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNPS1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for RNPS1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNPS1 |
| |  | |
|
|
|
