Aliases for RNPC3 Gene
External Ids for RNPC3 Gene
Previous GeneCards Identifiers for RNPC3 Gene
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RNPC3 Gene
RNPC3 (RNA-Binding Region (RNP1, RRM) Containing 3) is a Protein Coding gene. Diseases associated with RNPC3 include growth hormone deficiency, isolated, type ia and connective tissue disease. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is RBM41.
UniProtKB/Swiss-Prot for RNPC3 Gene
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3-stem-loop of m(7)G-capped U12 snRNA.