Aliases for RNPC3 Gene
External Ids for RNPC3 Gene
Previous GeneCards Identifiers for RNPC3 Gene
Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008]
GeneCards Summary for RNPC3 Gene
RNPC3 (RNA Binding Region (RNP1, RRM) Containing 3) is a Protein Coding gene. Diseases associated with RNPC3 include growth hormone deficiency, isolated, type ia and parainfluenza virus type 3. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBM41.
UniProtKB/Swiss-Prot for RNPC3 Gene
Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3-stem-loop of m(7)G-capped U12 snRNA.