Aliases for RNLS Gene
Aliases for RNLS Gene
External Ids for RNLS Gene
- HGNC: 25641
- Entrez Gene: 55328
- Ensembl: ENSG00000184719
- OMIM: 609360
- UniProtKB: Q5VYX0
Previous HGNC Symbols for RNLS Gene
- C10orf59
Previous GeneCards Identifiers for RNLS Gene
- GC10M090024
- GC10M083668
- GC10M088273
Summaries for RNLS Gene
-
Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney (Xu et al., 2005 [PubMed 15841207]).[supplied by OMIM, Mar 2008]
GeneCards Summary for RNLS Gene
RNLS (Renalase, FAD Dependent Amine Oxidase) is a Protein Coding gene. Diseases associated with RNLS include Chronic Kidney Failure. GO annotations related to this gene include oxidoreductase activity.
UniProtKB/Swiss-Prot for RNLS Gene
-
Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNLS Gene
Genomics for RNLS Gene
Regulatory Elements for RNLS Gene
Enhancers for RNLS Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around RNLS on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the RNLS gene promoter:
Regulatory Element Products
Genomic Location for RNLS Gene
- Chromosome:
- 10
- Start:
- 88,180,643 bp from pter
- End:
- 88,584,530 bp from pter
- Size:
- 403,888 bases
- Orientation:
- Minus strand
Genomic View for RNLS Gene
Genes around RNLS on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q23.31 by Ensembl
- 10q23.31 by Entrez Gene
- 10q23.31 by HGNC
RNLS Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RNLS Gene
Proteins for RNLS Gene
-
Protein details for RNLS Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5VYX0-RNLS_HUMAN
- Recommended name:
- Renalase
- Protein Accession:
- Q5VYX0
- Q9BS33
- Q9NUP8
Protein attributes for RNLS Gene
- Size:
- 342 amino acids
- Molecular mass:
- 37847 Da
- Cofactor:
- Name=FAD; Xref=ChEBI:CHEBI:57692;
- Quaternary structure:
- No Data Available
Protein Expression for RNLS Gene
Post-translational modifications for RNLS Gene
Other Protein References for RNLS Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for RNLS (Renalase)
- Novus Biologicals Antibodies for RNLS
-
Abcam antibodies for RNLS
-
Cloud-Clone Corp. Antibodies for RNLS
- Invitrogen Antibodies for RNLS
- antibodies-online Antibodies for RNLS: See all 66
- GeneTex RNLS antibody for RNLS
Protein Products
-
OriGene Purified Proteins for RNLS
- Search Origene for MassSpec and Protein Over-expression Lysates for RNLS
- Origene Custom Protein Services for RNLS
- ProSpec Recombinant Proteins for RNLS
-
Cloud-Clone Corp. Proteins for RNLS
- antibodies-online Proteins for RNLS: See all 16
- Search antibodies-online for peptides
- Search GeneTex for Proteins for RNLS
-
Abcam proteins for RNLS
No data available for DME Specific Peptides for RNLS Gene
Domains & Families for RNLS Gene
Protein Domains for RNLS Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for RNLS Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5VYX0- Family:
-
- Belongs to the renalase family.
No data available for Gene Families for RNLS Gene
Function for RNLS Gene
Molecular function for RNLS Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- 1,2-dihydro-beta-NAD(P) + H(+) + O(2) = beta-NAD(P)(+) + H(2)O(2).
- UniProtKB/Swiss-Prot CatalyticActivity:
- 1,6-dihydro-beta-NAD(P) + H(+) + O(2) = beta-NAD(P)(+) + H(2)O(2).
- UniProtKB/Swiss-Prot Function:
- Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Enzyme Numbers (IUBMB) for RNLS Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016491 | oxidoreductase activity | IEA | -- |
Phenotypes for RNLS Gene
- MGI mutant phenotypes for RNLS:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RNLS:
Animal Models for RNLS Gene
- MGI Knock Outs for RNLS:
-
- Rnls tm1Gvd
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNLS
-
-
ViGene Biosciences lentiviral particle packaged cDNA for RNLS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RNLS gene
- Search ViGene Biosciences for RNLS
CRISPR Products
-
OriGene CRISPR knockouts for RNLS
- GenScript: Design CRISPR guide RNA sequences for RNLS
miRNA for RNLS Gene
- miRTarBase miRNAs that target RNLS
-
- hsa-mir-5196-5p (MIRT458071)
- hsa-mir-4747-5p (MIRT458073)
- hsa-mir-4708-3p (MIRT458074)
- hsa-mir-892c-5p (MIRT458075)
- hsa-mir-9500 (MIRT458076)
- hsa-mir-6822-5p (MIRT458077)
- hsa-mir-6750-5p (MIRT458078)
- hsa-mir-5584-5p (MIRT458079)
- hsa-mir-4735-3p (MIRT458080)
- hsa-mir-18b-5p (MIRT458081)
- hsa-mir-18a-5p (MIRT458082)
- hsa-mir-548n (MIRT458083)
miRNA Products
- Search ViGene Biosciences for RNLS
Inhibitory RNA Products
- Origene shRNA, siRNA, rat_shrna, and RNAi products in human, mouse, rat for RNLS
- Browse OriGene Inhibitory RNA Products For RNLS
-
ViGene Biosciences ready-to-package AAV shRNAs for RNLS gene
Clone Products
- Sino Biological Human cDNA Clone for RNLS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RNLS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNLS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for RNLS
-
ViGene Biosciences adenoviral particle packaged cDNA for RNLS gene
-
ViGene Biosciences lentiviral particle packaged cDNA for RNLS gene
-
ViGene Biosciences ready-to-package AAV shRNAs for RNLS gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RNLS Gene
Localization for RNLS Gene
Subcellular locations from UniProtKB/Swiss-Prot for RNLS Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 3 |
| peroxisome | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA | -- |
| GO:0005615 | extracellular space | IEA | -- |
Pathways & Interactions for RNLS Gene
No Data Available
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002931 | response to ischemia | IEA | -- |
| GO:0055114 | oxidation-reduction process | IEA | -- |
| GO:0071869 | response to catecholamine | IEA | -- |
| GO:0071871 | response to epinephrine | IEA | -- |
| GO:1902074 | response to salt | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for RNLS Gene
Drugs & Compounds for RNLS Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| FAD | Approved | Pharma | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for RNLS Gene
mRNA/cDNA for RNLS Gene
- (15) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (44) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for RNLS Gene
- Renalase, FAD-dependent amine oxidase:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for RNLS
- GenScript: Design CRISPR guide RNA sequences for RNLS
miRNA Products
- Search ViGene Biosciences for RNLS
Inhibitory RNA Products
- Origene shRNA, siRNA, rat_shrna, and RNAi products in human, mouse, rat for RNLS
- Browse OriGene Inhibitory RNA Products For RNLS
-
ViGene Biosciences ready-to-package AAV shRNAs for RNLS gene
Clone Products
- Sino Biological Human cDNA Clone for RNLS
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for RNLS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNLS
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: |
Expression for RNLS Gene
This gene is overexpressed in Ovary (29.6), Skin (21.2), and Adrenal (6.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RNLS Gene
NURSA nuclear receptor signaling pathways regulating expression of RNLS Gene:
RNLSSOURCE GeneReport for Unigene cluster for RNLS Gene:
Hs.149849mRNA Expression by UniProt/SwissProt for RNLS Gene:
Q5VYX0-RNLS_HUMAN
Tissue specificity:
Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects.
Primer Products
-
OriGene qPCR primer pairs and template standards for RNLS
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein tissue co-expression partners for RNLS Gene
Orthologs for RNLS Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RNLS 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | RNLS 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Rnls 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Rnls 35 16 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RNLS 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | RNLS 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | RNLS 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RNLS 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | RNLS 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | rnls 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.14218 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | rnls 34 35 |
|
- Species where no ortholog for RNLS was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for RNLS Gene
No data available for Paralogs for RNLS Gene
Variants for RNLS Gene
| SNP ID | Clin | Chr 10 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1023643 | -- | 88,412,058(+) | actga(C/T)gaatt | intron-variant | |
| rs1035796 | -- | 88,291,940(+) | GCGTT(C/T)TAGCT | intron-variant | |
| rs1035797 | -- | 88,292,100(+) | ACATT(A/C)TTCCA | intron-variant | |
| rs10400114 | -- | 88,442,822(+) | TAGCT(C/G/T)GTATC | intron-variant | |
| rs10430643 | -- | 88,550,323(+) | ACTTA(C/T)GTAGA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv270e212 | CNV | loss | 25503493 |
| dgv271e212 | CNV | loss | 25503493 |
| esv2075872 | CNV | deletion | 18987734 |
| esv2662982 | CNV | deletion | 23128226 |
| esv3375666 | CNV | insertion | 20981092 |
| esv3624124 | CNV | loss | 21293372 |
| esv3624125 | CNV | gain | 21293372 |
| esv3624126 | CNV | gain | 21293372 |
| esv3624131 | CNV | loss | 21293372 |
| esv3624132 | CNV | gain | 21293372 |
| esv3624134 | CNV | gain | 21293372 |
| esv3891883 | CNV | loss | 25118596 |
| nsv1037657 | CNV | loss | 25217958 |
| nsv1054984 | CNV | loss | 25217958 |
| nsv1134038 | CNV | deletion | 24896259 |
| nsv24973 | CNV | deletion | 16902084 |
| nsv467414 | CNV | loss | 19166990 |
| nsv477695 | CNV | novel sequence insertion | 20440878 |
| nsv551838 | CNV | loss | 21841781 |
| nsv551839 | CNV | loss | 21841781 |
| nsv825500 | CNV | loss | 20364138 |
| nsv825501 | CNV | loss | 20364138 |
Residual Variation Intolerance Score:
66.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.13;
90.30% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for RNLS Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNLS Gene
Disorders for RNLS Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chronic kidney failure |
|
Search RNLS in MalaCards
View complete list of genes associated with diseases
Relevant External Links for RNLS
No data available for UniProtKB/Swiss-Prot and Genatlas for RNLS Gene
Publications for RNLS Gene
- Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure. (PMID: 15841207) Xu J. … Desir G.V. (J. Clin. Invest. 2005) 2 3 4 22 64
- Renalase, a new renal hormone: its role in health and disease. (PMID: 17565281) Xu J. … Desir G.V. (Curr. Opin. Nephrol. Hypertens. 2007) 2 3 22 64
- Metabolic function for human renalase: oxidation of isomeric forms of I^-NAD(P)H that are inhibitory to primary metabolism. (PMID: 25531177) Beaupre B.A. … Moran G.R. (Biochemistry 2015) 3 4 64
- FAD-binding site and NADP reactivity in human renalase: a new enzyme involved in blood pressure regulation. (PMID: 21699903) Milani M. … Aliverti A. (J. Mol. Biol. 2011) 3 4 64
- Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves. (PMID: 20168325) Hennebry S.C. … Schlaich M. (Mol. Psychiatry 2010) 3 22 64
Products for RNLS Gene
- R&D Systems Antibodies for RNLS (Renalase)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for RNLS
- Search Origene for MassSpec and Protein Over-expression Lysates for RNLS
- Origene Custom Protein Services for RNLS
- Origene shRNA, siRNA, rat_shrna, and RNAi products in human, mouse, rat for RNLS
- Browse OriGene Inhibitory RNA Products For RNLS
- OriGene qPCR primer pairs and template standards for RNLS
- OriGene CRISPR knockouts for RNLS
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RNLS
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for RNLS
- GenScript Custom Assay Services for RNLS
- GenScript Custom overexpressing Cell Line Services for RNLS
- GenScript: Design CRISPR guide RNA sequences for RNLS
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for RNLS
- Sino Biological Human cDNA Clone for RNLS
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for RNLS
- Novus Biologicals proteins and lysates for RNLS
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Abcam antibodies for RNLS
- Abcam proteins for RNLS
- Search for Assays for RNLS at Abcam
- Find your target
- Search knockout validated antibodies
- Browse monoclonal antibodies
- ProSpec Recombinant Proteins for RNLS
- Cloud-Clone Corp. Antibodies for RNLS
- Cloud-Clone Corp. Proteins for RNLS
- Cloud-Clone Corp Assay Kits for RNLS
- antibodies-online Antibodies for RNLS: See all 66
- antibodies-online Kits for RNLS: See all 11
- antibodies-online Proteins for RNLS: See all 16
- Search antibodies-online for peptides
- GeneTex RNLS antibody for RNLS
- Search GeneTex for Proteins for RNLS
- ViGene Biosciences adenoviral particle packaged cDNA for RNLS gene
- ViGene Biosciences lentiviral particle packaged cDNA for RNLS gene
- ViGene Biosciences ready-to-package AAV shRNAs for RNLS gene
- Search ViGene Biosciences for RNLS
- Horizon Cell Lines for RNLS
- Cyagen custom Knockout/knockin (KOKI) mouse models for RNLS
- VectorBuilder custom plasmid, inducible vectors for RNLS
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RNLS
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for RNLS Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab