RNH1 Gene
protein-coding GIFtS: 51
GCID: GC11M000485
|
|
ribonuclease/angiogenin inhibitor 1(Previous name: ribonuclease/angiogenin inhibitor )
(Previous symbol: RNH)
| |
Aliases
for RNH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ribonuclease/Angiogenin Inhibitor 11 2 3 | | Placental RNase Inhibitor2 3 | | RNH1 2 3 5 | | Ribonuclease/Angiogenin Inhibitor1 | | RAI1 2 3 | | Ribonuclease Inhibitor2 | | Placental Ribonuclease Inhibitor2 3 | | PRI3 |
Export aliases for RNH1 gene to outside databasesPrevious GC identifer: GC11M000310 |
Summaries
for RNH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RNH1:
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occurin many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 (PubMed3219362)). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation ofangiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form.Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNHmay be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversiblein vivo.(supplied by OMIM, Jul 2010)
UniProtKB/Swiss-Prot: RINI_HUMAN, P13489Function: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis
Gene Wiki entry for RNH1
|
Genomic Views
for RNH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNH1 gene promoter:
GR AML1a GATA-1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNH1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNH1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.5 Ensembl cytogenetic band: 11p15.5 HGNC cytogenetic band: 11p15.5RNH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M000485: view genomic region
(about GC identifiers)
Start:
|
494,512 bp from pter |
End:
|
507,300 bp from pter |
Size:
|
12,789 bases |
Orientation:
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minus strand |
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Proteins
for RNH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RINI_HUMAN, P13489 (See
protein sequence)Recommended Name: Ribonuclease inhibitor Size: 461 amino acids; 49973 Da
Subunit: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2
Subcellular location: Cytoplasm
4 PDB 3D structures from  and Proteopedia  for RNH1:1A4Y (3D)
1Z7X (3D)
2BEX (3D)
2Q4G (3D)
Secondary accessions: Q8IZK8 Q96FD7 Q9BQ80 Q9UDK6Explore the universe of human proteins at neXtProt for RNH1: NX_P13489
Post-translational modifications:
The N-terminus is blocked1
At least 30 of the 32 cysteine residues are in the reduced form1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P13489
RNH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (8 alternative transcripts):
NP_002930.2 NP_976317.1 NP_976318.1 NP_976319.1 NP_976320.1 NP_976321.1 NP_976322.1 NP_976323.1
ENSEMBL proteins: ENSP00000433999 ENSP00000380739 ENSP00000380729 ENSP00000436022 ENSP00000432170 ENSP00000435594 ENSP00000416589 ENSP00000346402 ENSP00000348515 ENSP00000431201 ENSP00000433033 ENSP00000435748 ENSP00000435057 ENSP00000434947 ENSP00000435798 ENSP00000434971 ENSP00000432781 ENSP00000380738
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RNH1 for ontologies About GeneDecksing
RNH1 Antibody Products:
Assay Products for RNH1: |
Protein
Domains /
Families
for RNH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNH1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry P13489ProtoNet protein and cluster: P13489 1 Blocks protein family: IPB003590 Leucine-rich repeat
UniProtKB/Swiss-Prot: RINI_HUMAN, P13489Domain: The LRR domain forms a horseshoe-shaped structure that interacts tightly with target RNases via a large proteininteraction surface on its interior sideSimilarity: Contains 15 LRR (leucine-rich) repeats |
Function
for RNH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RINI_HUMAN, P13489Function: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 (see all 9)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 8): RNH1 (NM_002939) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNH1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNH1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
RNH1 for ontologies About GeneDecksing
|
Pathways & Interactions
for RNH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNH1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
5/29 Interacting proteins for RNH1 (P134891, 2, 3 ENSP000003464024) via UniProtKB, MINT, STRING, and/or I2D (see all 29)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ANG | P039501, 3, ENSP000003367624 | EBI-1237106,EBI-525291 I2D:
score=4 STRING: ENSP00000336762 | | RNASE1 | P079981, 3, ENSP000003441934 | EBI-1237106,EBI-2823523 I2D:
score=3 STRING: ENSP00000344193 | | PARP1 | P098742, 3, ENSP000003557594 | MINT-8086548 I2D:
score=1 STRING: ENSP00000355759 | | MYC | P011063, ENSP000003672074 | I2D:
score=3 STRING: ENSP00000367207 | | RNASE2 | P101533, ENSP000003032764 | I2D:
score=2 STRING: ENSP00000303276 |
About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table
RNH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for RNH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RNH1
Search CenterWatch for drugs/clinical trials and news about RNH1 / RINI
|
Transcripts
for RNH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNH1 gene (8 alternative transcripts): NM_002939.3 NM_203383.1 NM_203384.1 NM_203385.1 NM_203386.2 NM_203387.2 NM_203388.2 NM_203389.2 Unigene Cluster for RNH1: Ribonuclease/angiogenin inhibitor 1 Hs.530687 [show with all ESTs]Unigene Representative Sequence: AB20919618/25 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 25): ENST00000534797(uc001lpk.1) ENST00000397615(uc001lpl.1 uc001lpn.1)
ENST00000397604(uc001lps.2) ENST00000525522 ENST00000525701 ENST00000529768
ENST00000533410(uc001lpr.2) ENST00000438658 ENST00000354420(uc001lpp.2)
ENST00000356187(uc001lpq.2) ENST00000524464 ENST00000529115 ENST00000527485
ENST00000529368 ENST00000529306 ENST00000524780 ENST00000531149 ENST00000531223
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 (see all 11)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 (see all 9)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 8): RNH1 (NM_002939) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNH1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNH1 |
Additional cDNA sequence: AB209196.1 AK095144.1 AK308340.1 AK310173.1 AK311379.1 AY071904.2 BC000677.2 BC003506.1 BC011186.1 BC011500.1 BC014629.2 BC024037.1 BC047730.1 M22414.1 M36717.1 X13973.1 24/41 DOTS entries (see all 41): DT.100888996 DT.91767822 DT.100889006 DT.91767841 DT.91805855 DT.102835588 DT.91767837 DT.95113324 DT.91767833 DT.100691026 DT.91815635 DT.95113378 DT.100888990 DT.100889007 DT.75192219 DT.95113384 DT.100888987 DT.95113383 DT.95191671 DT.91767834 DT.95313613 DT.95361649 DT.100888993 DT.95113386 24/859 AceView cDNA sequences (see all 859): BU189612 BU943963 BG822992 BM764669 AW161573 BU944530 BX356989 CA431347 BM988410 AI582152 CF272214 BM807512 BQ927358 CR598809 CD364659 BM917533 BI833176 CR600411 BQ653015 BM928010 BF203540 NM_203384 CR612687 BE791436
GeneLoc Exon Structure
5/32 Alternative Splicing Database (ASD) splice patterns (SP) for RNH1 (see all 32) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2a | · | 2b | · | 2c | · | 2d | · | 2e | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | | | - | | - | | | | | | | | | | | | - | | - | | |
| SP2: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | | | | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | - | |
| ExUns: | 10b | · | 10c | · | 10d | · | 10e | ^ | 11a | · | 11b | · | 11c | · | 11d | · | 11e | · | 11f | · | 11g | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | · | 13c | · | 13d | ^ | 14a | · | 14b | · | 14c | ^ | 15a | · | 15b | · | 15c | · | 15d | · | 15e | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15f | · | 15g | · | 15h | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RNH1
|
Expression
for RNH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCTCACCCT
About this image
See RNH1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNH1
SOURCE GeneReport for Unigene cluster: Hs.530687
SABiosciences Expression via Pathway-Focused PCR Array including RNH1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNH1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RNH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNH1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNH1 |
Orthologs
for RNH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for RNH1 gene from 3/10 species (see all 10) About this table
ENSEMBL Gene Tree for RNH1 (if available)
TreeFam Gene Tree for RNH1 (if available) |
Paralogs
for RNH1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNH1 gene
- LRRC312
12 SIMAP similar genes for RNH1 using alignment to 10 protein entries: RINI_HUMAN (see all proteins):NLRP1 NLRP12 NLRP11 NLRP7 NLRP4 NLRP14
NLRP9 CIAS1 NLRP3 NLRP5 PP1579 NLRP2
RNH1 for paralogs About GeneDecksing
|
Genomic Variants
for RNH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RNH1 (494512 - 507300 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for RNH1
4 CNVs: 3831 29882 29883 29881
3 Indels: 85583 85584 75486 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNH1 |
|
Disorders
/ Diseases
for RNH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RNH1 for disorders About GeneDecksing
OMIM gene information: 173320
OMIM disorders: --
8  diseases for RNH1: About MalaCardsbasal cell carcinoma malignant mesothelioma vaginal cancer vaginitis
endometriosis schizophrenia carcinoma pancreatitis
2 Novoseek disease relationships for RNH1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
4 |
15592448 (1), 1544320 (1), 17032310 (1) |
| cancer |
0 |
1 |
11801605 (1) |
Genetic Association Database (GAD): RNH1
Human Genome Epidemiology (HuGE) Navigator: RNH1 (2 documents)
Export disorders for RNH1 gene to outside databases
|
Publications
for RNH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNH1 gene, integrated from 9 sources (see all 69):
(articles sorted by number of sources associating them with RNH1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein. (PubMed id 17350650)1, 2, 9 Johnson R.J....Raines R.T. (2007)
- Molecular recognition of human eosinophil-derived neurotoxin (RNase 2) by placental ribonuclease inhibitor. (PubMed id 15755456)1, 2 Iyer S....Acharya K.R. (2005)
- Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50. (PubMed id 15936590)1, 4 Vogel U....Nexo B.A. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Superadditive and subadditive effects of 'hot spot' mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A. (PubMed id 10413501)1, 2 Chen C.Z. and Shapiro R. (1999)
- Molecular recognition of human angiogenin by placental ribonuclease inhibitor -- an X-ray crystallographic study at 2.0-A resolution. (PubMed id 9311977)1, 2 Papageorgiou A.C.... Acharya K.R. (1997)
- Purification and characterization of human brain ribonuclease inhibitor. (PubMed id 8037455)1, 2 Nadano D.... Kishi K. (1994)
- Primary structure of human placental ribonuclease inhibitor. (PubMed id 3219362)1, 2 Lee F.S.... Vallee B.L. (1988)
- The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module. (PubMed id 3243277)1, 2 Schneider R....Schweiger M. (1988)
- Anti-tumor effect of hematopoietic cells carrying the gene of ribonuclease inhibitor. (PubMed id 15592448)1, 9 Fu P....Zhao B. (2005)
|
External Searches for RNH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RNH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNH1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNH1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RNH1 gene:
Search GeneIP for patents involving RNH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RNH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for RNH1 | | OriGene shRNA RFP for RNH1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNH1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNH1 | | | OriGene Protein Over-expression Lysate for RNH1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RNH1 | | OriGene 3'-UTR Clone for RNH1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNH1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RNH1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RNH1 | | OriGene Custom Protein Services for RNH1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNH1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNH1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNH1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNH1 |
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| | | | Search Tocris compounds for RNH1 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNH1 |
|  |  |  | | | | Search ThermoFisher Antibodies for RNH1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNH1 |
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