Aliases for RNGTT Gene
External Ids for RNGTT Gene
Previous GeneCards Identifiers for RNGTT Gene
GeneCards Summary for RNGTT Gene
RNGTT (RNA Guanylyltransferase And 5'-Phosphatase) is a Protein Coding gene. Diseases associated with RNGTT include Cecum Adenocarcinoma. Among its related pathways are mRNA surveillance pathway and Formation of HIV elongation complex in the absence of HIV Tat. GO annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.
UniProtKB/Swiss-Prot for RNGTT Gene
Bifunctional mRNA-capping enzyme exhibiting RNA 5-triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5-diphosphate terminus.