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RNFT2 Gene

protein-coding   GIFtS: 47
GCID: GC12P117176

Ring Finger Protein, Transmembrane 2

(Previous name: transmembrane protein 118)
(Previous symbol: TMEM118)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ring Finger Protein, Transmembrane 21 2
Transmembrane Protein 1181 2 3
TMEM1181 2 3
RING Finger And Transmembrane Domain-Containing Protein 22

External Ids:    HGNC: 259051   Entrez Gene: 849002   Ensembl: ENSG000001351197   UniProtKB: Q96EX23   

Export aliases for RNFT2 gene to outside databases

Previous GC identifers: GC12P115660 GC12P114185


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RNFT2 Gene:
RNFT2 (ring finger protein, transmembrane 2) is a protein-coding gene. Diseases associated with RNFT2 include obesity, and alzheimer's disease. An important paralog of this gene is RNFT1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_029419.13  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RNFT2 gene promoter:
         STAT5B   STAT1   STAT4   STAT6   STAT1beta   STAT5A   STAT1alpha   STAT2   STAT3   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNFT2 promoter sequence
   Search Chromatin IP Primers for RNFT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RNFT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.22   Ensembl cytogenetic band:  12q24.22   HGNC cytogenetic band: 12q24.22

RNFT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNFT2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P117176:  view genomic region     (about GC identifiers)

Start:
117,176,096 bp from pter      End:
117,291,436 bp from pter
Size:
115,341 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: RNFT2_HUMAN, Q96EX2 (See protein sequence)
Recommended Name: RING finger and transmembrane domain-containing protein 2  
Size: 444 amino acids; 48965 Da
Sequence caution: Sequence=AAH11878.1; Type=Erroneous initiation;
Secondary accessions: Q96SU5
Alternative splicing: 4 isoforms:  Q96EX2-1   Q96EX2-2   Q96EX2-3   Q96EX2-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RNFT2: NX_Q96EX2

Explore proteomics data for RNFT2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys360
  • Modification sites at PhosphoSitePlus

  • See RNFT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001103373.1  NP_116203.2  

    ENSEMBL proteins: 
     ENSP00000257575   ENSP00000385669   ENSP00000321405   ENSP00000447294   ENSP00000376332  

    RNFT2 Human Recombinant Protein Products:

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    Novus Biologicals RNFT2 Antibody
    Abcam antibodies for RNFT2
    Cloud-Clone Corp. Antibodies for RNFT2
    ThermoFisher Antibodies for RNFT2
    LSBio Antibodies in human, mouse, rat for RNFT2

    RNFT2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RNFT2
    Cloud-Clone Corp. CLIAs for RNFT2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RNF: RING-type (C3HC4) zinc fingers

    3 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q96EX2

    ProtoNet protein and cluster: Q96EX2

    UniProtKB/Swiss-Prot: RNFT2_HUMAN, Q96EX2
    Similarity: Contains 1 RING-type zinc finger


    RNFT2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0009055electron carrier activity ----
    GO:0046872metal ion binding ----
    GO:0051536iron-sulfur cluster binding ----
         
    RNFT2 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RNFT2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RNFT2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RNFT2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RNFT2

    miRNA
    Products:
        
    miRTarBase miRNAs that target RNFT2:
    hsa-mir-197-3p (MIRT048111)

    Block miRNA regulation of human, mouse, rat RNFT2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNFT2 (see all 13):
    hsa-miR-548d-3p hsa-miR-146b-3p hsa-miR-186* hsa-miR-2278 hsa-miR-488 hsa-miR-431 hsa-miR-548aa hsa-miR-508-3p
    SwitchGear 3'UTR luciferase reporter plasmidRNFT2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RNFT2
    Predesigned siRNA for gene silencing in human, mouse, rat RNFT2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RNFT2

    Clone
    Products:
         
    OriGene clones in human, mouse for RNFT2 (see all 14)
    OriGene ORF clones in mouse, rat for RNFT2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RNFT2 (NM_032814)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNFT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNFT2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for RNFT2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNFT2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    RNFT2_HUMAN, Q96EX2: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    nucleus2
    plasma membrane2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    RNFT2 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for RNFT2
    Interactions:

        Search GeneGlobe Interaction Network for RNFT2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for RNFT2 (ENSP000002575754) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MCM4ENSP000002621054STRING: ENSP00000262105
    ORC1ENSP000003606214STRING: ENSP00000360621
    SUPT16HENSP000002162974STRING: ENSP00000216297
    SEC61A1ENSP000002432534STRING: ENSP00000243253
    SEC61A2ENSP000002984284STRING: ENSP00000298428
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RNFT2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for RNFT2 gene (2 alternative transcripts): 
    NM_001109903.1  NM_032814.3  

    Unigene Cluster for RNFT2:

    Ring finger protein, transmembrane 2
    Hs.437195  [show with all ESTs]
    Unigene Representative Sequence: NM_001109903
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000257575 ENST00000407967(uc001twb.4 uc001twa.4) ENST00000319176
    ENST00000552920 ENST00000547718 ENST00000551251 ENST00000392549(uc009zwn.3 uc001twc.4)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RNFT2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNFT2 (see all 13):
    hsa-miR-548d-3p hsa-miR-146b-3p hsa-miR-186* hsa-miR-2278 hsa-miR-488 hsa-miR-431 hsa-miR-548aa hsa-miR-508-3p
    SwitchGear 3'UTR luciferase reporter plasmidRNFT2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RNFT2
    Predesigned siRNA for gene silencing in human, mouse, rat RNFT2
    Clone
    Products:
         
    OriGene clones in human, mouse for RNFT2 (see all 14)
    OriGene ORF clones in mouse, rat for RNFT2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): RNFT2 (NM_032814)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNFT2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNFT2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for RNFT2
    OriGene qSTAR qPCR primer pairs in human, mouse for RNFT2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RNFT2
      QuantiTect SYBR Green Assays in human, mouse, rat RNFT2
      QuantiFast Probe-based Assays in human, mouse, rat RNFT2

    Additional mRNA sequence: 

    AK027533.1 AK093164.1 AK094682.1 AY358585.1 BC011878.2 

    8 DOTS entries:

    DT.100741351  DT.100024748  DT.210904  DT.97779546  DT.100024747  DT.121167512  DT.121167501  DT.121167522 

    Selected AceView cDNA sequences (see all 106):

    CA432422 AL120375 CR608078 AI539767 BM702979 BQ877316 BU849935 Z41688 
    BU931935 BU658750 AA322769 BU727279 BE880269 AA774545 AA918185 AI700597 
    BU687238 BI828452 AI004507 AA584146 BC011878 BX643270 AW628698 AK027533 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RNFT2    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15
    SP1:                                                                                                            
    SP2:                                                        -                                                   
    SP3:                                                                                                            
    SP4:              -     -                                                                                       


    ECgene alternative splicing isoforms for RNFT2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RNFT2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCACCAAAAC
    RNFT2 Expression
    About this image

    RNFT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RNFT2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.437195
        Custom PCR Arrays for RNFT2
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    QuantiFast Probe-based Assays in human, mouse, rat RNFT2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNFT2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RNFT2 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnft21 , 5 ring finger protein, transmembrane 21, 5 87.54(n)1
    92.12(a)1
      5 (58.20 cM)5
    2696951  NM_172998.31  NP_766586.21 
     1181907365 
    chicken
    (Gallus gallus)
    Aves RNFT21 ring finger protein, transmembrane 2 79.02(n)
    84.21(a)
      427723  XM_425298.4  XP_425298.4 
    lizard
    (Anolis carolinensis)
    Reptilia RNFT26
    ring finger protein, transmembrane 2
    80(a)
    1 ↔ 1
    LGb(2294739-2310096)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rnft21 ring finger protein, transmembrane 2 66.82(n)
    70.05(a)
      100486948  XM_002936409.2  XP_002936455.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rnft21 ring finger protein, transmembrane 2 67.91(n)
    67.6(a)
      553554  NM_001020533.1  NP_001018369.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG136056
    --
    13(a)
    1 → many
    3R(19935666-19938124)
    worm
    (Caenorhabditis elegans)
    Secernentea ZC13.11 ZC13.1 41.76(n)
    26.69(a)
      180437  NM_001029799.3  NP_001024970.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G019601 AT5G01960 44.01(n)
    31.7(a)
      831906  NM_120274.3  NP_568096.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g01684001 Os01g0168400 44.25(n)
    31.36(a)
      4325191  NM_001048664.1  NP_001042129.1 


    ENSEMBL Gene Tree for RNFT2 (if available)
    TreeFam Gene Tree for RNFT2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RNFT2 gene
    RNFT12  
    1 SIMAP similar gene for RNFT2 using alignment to 5 protein entries:     RNFT2_HUMAN (see all proteins):
    RNFT1

    RNFT2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RNFT2
    PGOHUM00000259166


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RNFT2 (see all 2566)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs667347821,2
    C--114269178(+) GTTTC-/T/TTT 
            
    TTTTT
    2 -- int11NA 2
    rs19690171,2
    C,H--117177864(+) AAATTA/GGGTGG 2 -- int16Minor allele frequency- G:0.00NA WA CSA 10
    rs1415274561,2
    --117177866(+) ATTGGG/TTGGGC 2 -- int10--------
    rs3685198511,2
    C--117177988(+) AAAAA-/AGGAGT 2 -- int10--------
    rs358749131,2
    C--117178072(+) TAGCTA/GCCAAC 2 -- int12Minor allele frequency- G:0.25NA 4
    rs1831609381,2
    --117178089(+) CTAAGA/GCTTCT 2 -- int10--------
    rs21729531,2
    C,F,H--117178112(+) GGTATC/TGCAGG 2 -- int115Minor allele frequency- T:0.04NS EA NA CSA WA 1885
    rs1881342221,2
    --117178198(+) GAGACA/GAAGAG 2 -- ut510--------
    rs1508762611,2
    --117178209(+) GAGGGG/TGAGGC 2 -- ut510--------
    rs1927534081,2
    C--117178220(+) CTGTCC/TTCTCT 2 -- ut510--------

    HapMap Linkage Disequilibrium report for RNFT2 (117176096 - 117291436 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for RNFT2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658721CNV Deletion23128226
    esv2660236CNV Deletion23128226
    esv1515587CNV Deletion17803354
    esv2672682CNV Deletion23128226
    nsv898CNV Insertion18451855
    nsv53492CNV Loss16902084
    nsv832523CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RNFT2
    DNA2.0 Custom Variant and Variant Library Synthesis for RNFT2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for RNFT2:    
    About MalaCards
    obesity    alzheimer's disease


    RNFT2 for disorders           About GeneDecksing


    Export disorders for RNFT2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RNFT2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RNFT2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    5. Genome-wide association analysis of age-at-onset in Alzheimer's disease. (PubMed id 22005931)1 Kamboh M.I....Lopez O.L. (Mol. Psychiatry 2012)
    6. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    7. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    8. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1 Clark H.F.... Gray A.M. (Genome Res. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84900 HGNC: 25905 AceView: FLJ14627 Ensembl:ENSG00000135119 euGenes: HUgn84900
    ECgene: RNFT2 H-InvDB: RNFT2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RNFT2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RNFT2 gene:
    Search GeneIP for patents involving RNFT2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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