RNF5 Gene
protein-coding GIFtS: 60
GCID: GC06P032146
|
|
ring finger protein 5, E3 ubiquitin protein ligase(Previous name: ring finger protein 5 )
| |
Aliases
for RNF5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ring Finger Protein 5, E3 Ubiquitin Protein Ligase1 2 | | Protein G162 3 | | RMA11 2 3 | | Ram1 Homolog2 3 | | RING51 2 5 | | E3 Ubiquitin-Protein Ligase RNF52 | | G161 3 | | EC 6.3.2.-3 | | NG21 3 | | HsRma13 | | RING Finger Protein 51 3 | | |
Export aliases for RNF5 gene to outside databasesPrevious GC identifers: GC06P032173 GC06P031916 GC06P032217 GC06P032254 |
Summaries
for RNF5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RNF5:
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-proteininteractions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillinubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942Function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugatingenzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secretedprotein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association withcomponents of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N.Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; theubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses
Gene Wiki entry for RNF5
|
Genomic Views
for RNF5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167246.1 NT_167247.1 NT_167248.1
- NT_167249.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNF5 gene promoter:
E2F-4 E2F-3a E2F-5 E2F-1 E2F p53 ARP-1 E2F-2 Tal-1beta E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNF5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.3 Ensembl cytogenetic band: 6p21.32 HGNC cytogenetic band: 6p21.31RNF5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P032146: view genomic region
(about GC identifiers)
Start:
|
32,146,131 bp from pter |
End:
|
32,151,930 bp from pter |
Size:
|
5,800 bases |
Orientation:
|
plus strand |
6 alternative locations:
| Chr6+,ALT_REF_LOCI_1 32,157,475-32,168,214 | Chr6+,ALT_REF_LOCI_4 32,108,645-32,111,053 | Chr6+,ALT_REF_LOCI_5 32,137,414-32,139,820 | | Chr6+,ALT_REF_LOCI_2 32,094,614-32,136,235 | Chr6+,ALT_REF_LOCI_6 32,103,754-32,141,774 | Chr6+,ALT_REF_LOCI_7 32,083,355-32,085,763 | |
|
Proteins
for RNF5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase RNF5 Size: 180 amino acids; 19881 Da
Subunit: Interacts with PXN. Interacts with Salmonella typhimurium sopA. Interacts with JKAMP. Interacts with TMEM173;the interaction of endogenous proteins is dependent on viral infection
Subcellular location: Membrane; Multi-pass membrane protein. Mitochondrion membrane. Endoplasmic reticulum membrane.Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles
Secondary accessions: A2BFI6 B2R4K3 Q0VDB7 Q9UMQ2Explore the universe of human proteins at neXtProt for RNF5: NX_Q99942
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q99942
RNF5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_008844.1
ENSEMBL proteins: ENSP00000364235 ENSP00000407656
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005789 | endoplasmic reticulum membrane |
IEA | -- | | GO:0016021 | integral to membrane |
IEA | -- | | GO:0031966 | mitochondrial membrane |
IEA | -- |
RNF5 for ontologies About GeneDecksing
RNF5 Antibody Products:
Assay Products for RNF5: |
Protein
Domains /
Families
for RNF5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNF5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q99942ProtoNet protein and cluster: Q99942 1 Blocks protein family: IPB001841 Zn-finger
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942Similarity: Contains 1 RING-type zinc finger |
Function
for RNF5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942Function: Has E2-dependent E3 ubiquitin-protein ligase activity. May function together with E2 ubiquitin-conjugatingenzymes UBE2D1/UBCH5A and UBE2D2/UBC4. Mediates ubiquitination of PXN/paxillin and Salmonella type III secretedprotein sopA. May be involved in regulation of cell motility and localization of PXN/paxillin. Mediates the'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association withcomponents of the proteasome and ERAD; the ubiquitination appears to involve E2 ubiquitin-conjugating enzyme UBE2N.Mediates the 'Lys-48'-linked polyubiquitination of TMEM173 at 'Lys-150' leading to its proteasomal degradation; theubiquitination occurrs in mitochondria after viral transfection and regulates antiviral responses Genatlas biochemistry entry for RNF5:RING zinc-finger protein 5,widely expressed,homolog of a putative zinc finger gene from C elegans,same as D6S115E
Enzyme Number (IUBMB): EC 6.3.2.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RNF5 (NM_006913) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF5 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
RNF5 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RNF5:
Animal Models:
Mouse knock-out Rnf5tm1Zron for RNF5
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Rnf5):
RNF5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for RNF5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Regulation of degradation of wt-CFTR | | | 2 | Protein processing in endoplasmic reticulum | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2  GeneGo (Thomson Reuters) Pathways for RNF5
1 
Kegg Pathway (Kegg details for RNF5):
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942Pathway: Protein modification; protein ubiquitination
RNF5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for RNF5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/32 Interacting proteins for RNF5 (Q999421, 2, 3 ENSP000003642354) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| UBE2D2 | P628371, 2, 3, ENSP000003817174 | EBI-348482,EBI-347677 MINT-62677 MINT-62753 MINT-62579 I2D:
score=5 STRING: ENSP00000381717 | | UBE2D3 | P610771, 2, 3, ENSP000003497224 | EBI-348482,EBI-2809412 MINT-62678 MINT-62754 MINT-62580 I2D:
score=5 STRING: ENSP00000349722 | | ABHD16A | O958702, 3, ENSP000003792824 | MINT-62601 MINT-62699 MINT-62775 I2D:
score=5 STRING: ENSP00000379282 | | FHOD1 | Q9Y6132, 3, ENSP000002582014 | MINT-62581 MINT-62755 MINT-62679 I2D:
score=5 STRING: ENSP00000258201 | | UBE2E3 | Q969T42, 3 | MINT-62676 MINT-62752 MINT-62578 I2D:
score=5 |
About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
RNF5 for ontologies About GeneDecksing
|
Drugs & Compounds
for RNF5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RNF5
4 HMDB Compounds for RNF5 About this table
Search CenterWatch for drugs/clinical trials and news about RNF5
|
Transcripts
for RNF5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNF5 gene: NM_006913.3 Unigene Cluster for RNF5: Ring finger protein 5, E3 ubiquitin protein ligase Hs.731774 [show with all ESTs]Unigene Representative Sequence: BX6483783 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000375094(uc003oaj.4) ENST00000487940 ENST00000427134
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RNF5 (NM_006913) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF5 |
Additional cDNA sequence: AB056869.1 AJ243936.1 AK296212.1 AK311221.1 AK311859.1 BC004155.2 BC020290.1 BC111392.1 BC119741.1 BC119742.1 BC127651.1 BC127652.1 BC148255.1 BT007105.1 BX648378.1 13 DOTS entries: DT.102845462 DT.91722873 DT.448281 DT.100757936 DT.121474131 DT.121378333 DT.121378227 DT.121378467 DT.95278813 DT.100781048 DT.91751156 DT.91751157 DT.95278806 24/345 AceView cDNA sequences (see all 345): CR593664 CA309746 AW241774 CB159440 AB056869 BF476680 BM474579 BE887085 CK429588 AI143856 CA309229 BQ575528 CB240817 BF968517 CR609098 BU849202 AA335554 AW794712 BU740331 AW575596 BI759232 BC020290 CD364919 BC004155
GeneLoc Exon Structure
|
Expression
for RNF5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNF5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCCTTTCCG
About this image
See RNF5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF5
SOURCE GeneReport for Unigene cluster: Hs.731774
UniProtKB/Swiss-Prot: RNF5_HUMAN, Q99942Tissue specificity: Widely expressed
SABiosciences Expression via Pathway-Focused PCR Arrays including RNF5:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF5
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF5 |
Orthologs
for RNF5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RNF5 gene from 8/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Rnf51 , 5 |
ring finger protein 51, 5 |
91.67(n)1
97.78(a)1 |
|
17 (18.18 cM)5
541971 NM_019403.31 NP_062276.11
346010915 |
lizard
(Anolis carolinensis) |
Reptilia |
RNF56 |
-- |
69(a) |
1 ↔ 1 |
2(198596445-198608219) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.153972 |
Xenopus laevis transcribed sequence with weak similarity more |
80.78(n) |
|
AW641687.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.130102 |
Transcribed sequence with weak similarity to protein more |
77.38(n) |
|
BI881878.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG89743 |
-- |
60(a) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
rnf-53 |
Zinc finger, C3HC4 type (RING finger) |
48(a) |
|
III(4236213-4238174) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G193101 |
RING/U-box domain-containing protein |
50.96(n)
46.28(a) |
|
838513 NM_101788.3 NP_564078.1 |
rice
(Oryza sativa) |
Liliopsida |
Os12g06360001 |
hypothetical protein |
57.84(n)
52.21(a) |
|
4352888 NM_001073893.1 NP_001067361.1 |
ENSEMBL Gene Tree for RNF5 (if available)
TreeFam Gene Tree for RNF5 (if available) |
Paralogs
for RNF5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNF5 gene
- RNF1852
7 SIMAP similar genes for RNF5 using alignment to 3 protein entries: RNF5_HUMAN (see all proteins):RNF185 TRIM37 RFWD2 BRCA1 RNF10 TRAIP
TRIM39
RNF5 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for RNF5
PGOHUM00000263131 PGOHUM00000249301
|
Genomic Variants
for RNF5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RNF5 (32146131 - 32151930 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for RNF5
2 CNVs: 3602 64475
1 Indel: 40850 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF5 |
|
Disorders
/ Diseases
for RNF5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RNF5 for disorders About GeneDecksing
OMIM gene information: 602677
OMIM disorders: --
9  diseases for RNF5: About MalaCardsinclusion body myositis systemic lupus erythematosus lupus erythematosus myositis
cystic fibrosis fibrosis myopathy breast cancer
malaria
Human Genome Epidemiology (HuGE) Navigator: RNF5 (4 documents)
Export disorders for RNF5 gene to outside databases
|
Publications
for RNF5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNF5 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with RNF5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans. (PubMed id 9533025)1, 2, 3 Kyushiki H.... Horie M. (1997)
- RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization. (PubMed id 12861019)1, 2, 9 Didier C....Ronai Z. (2003)
- The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. (PubMed id 19285439)1, 2 Zhong B....Shu H.B. (2009)
- Regulation of endoplasmic reticulum-associated degradation by RNF5-dependent ubiquitination of JNK-associated membrane protein (JAMP). (PubMed id 19269966)1, 2 Tcherpakov M....Ronai Z.A. (2009)
- Recognition and ubiquitination of Salmonella type III effector SopA by a ubiquitin E3 ligase, HsRMA1. (PubMed id 16176924)1, 2 Zhang Y.... Zhou D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PubMed id 14656967)1, 2 Xie T.... Hood L. (2003)
- Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase. (PubMed id 11329381)1, 2 Matsuda N.... Nakano A. (2001)
- Expression QTL analysis of top loci from GWAS meta-ana lysis highlights additional schizophrenia candidate genes. (PubMed id 22433715)1 de Jong S....Ophoff R.A. (2012)
|
External Searches for RNF5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RNF5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNF5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNF5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNF5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RNF5 gene:
Search GeneIP for patents involving RNF5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RNF5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RNF5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF5 | | | OriGene Protein Over-expression Lysate for RNF5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RNF5 | | OriGene 3'-UTR Clone for RNF5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RNF5 | | OriGene Custom Protein Services for RNF5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNF5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF5 |
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| | | | Search Tocris compounds for RNF5 |
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 | | | RNF5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF5 |
|  |  |  | | | | Search ThermoFisher Antibodies for RNF5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF5 |
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