RNF31 Gene
protein-coding GIFtS: 52
GCID: GC14P024616
|
|
ring finger protein 31
| |
Aliases
for RNF31 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ring Finger Protein 311 2 3 | | FLJ101111 | | ZIBRA1 2 3 5 | | FLJ235011 | | HOIP1 2 3 | | E3 Ubiquitin-Protein Ligase RNF312 | | Zinc In-Between-RING-Finger Ubiquitin-Associated Domain Protein2 3 | | EC 6.3.2.-3 | | HOIL-1-Interacting Protein2 3 | | |
Export aliases for RNF31 gene to outside databasesPrevious GC identifers: GC14P022606 GC14P023687 GC14P023688 GC14P004731 |
Summaries
for RNF31 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for RNF31:
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteinsand known to be involved in protein-DNA and protein-protein interactions. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: RNF31_HUMAN, Q96EP0Function: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('M-1'-linked)polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBACconjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and theJNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death andthereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) followingpolyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG andpossibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage types
Gene Wiki entry for RNF31
|
Genomic Views
for RNF31 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNF31 gene promoter:
TBP AML1a STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNF31
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF31 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q11.2 Ensembl cytogenetic band: 14q12 HGNC cytogenetic band: 14q11.2RNF31 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P024616: view genomic region
(about GC identifiers)
Start:
|
24,615,892 bp from pter |
End:
|
24,629,870 bp from pter |
Size:
|
13,979 bases |
Orientation:
|
plus strand |
|
Proteins
for RNF31 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RNF31_HUMAN, Q96EP0 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase RNF31 Size: 1072 amino acids; 119652 Da
Subunit: Interacts with MUSK (By similarity). Component of the LUBAC complex (linear ubiquitin chain assembly complex)which consists of SHARPIN, RBCK1 and RNF31. LUBAC has a MW of approximative 600 kDa suggesting a heteromultimericassembly of its subunits. Associates with the TNF-R1 signaling complex (TNF-RSC) in a stimulation-dependent manner
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAB15675.1; Type=Erroneous termination; Positions=1060; Note=Translated as Glu;Sequence=BAB15675.1; Type=Frameshift; Positions=1036; Sequence=BAB15675.1; Type=Miscellaneous discrepancy; Note=Intronretention; Sequence=BAB70948.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for RNF31:2CT7 (3D)
4DBG (3D)
Secondary accessions: A0A962 Q86VI2 Q8TEI0 Q96GB4 Q96NF1 Q9H5F1 Q9NWD2Alternative splicing: 3 isoforms: Q96EP0-1 Q96EP0-2 Q96EP0-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for RNF31: NX_Q96EP0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96EP0
RNF31 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_060469.4
ENSEMBL proteins: ENSP00000454032 ENSP00000453471 ENSP00000454048 ENSP00000453423 ENSP00000453948 ENSP00000453574 ENSP00000315112 ENSP00000453645 ENSP00000453595 ENSP00000453601 ENSP00000452972 ENSP00000453501 ENSP00000454140 ENSP00000453672 ENSP00000452820 ENSP00000372134
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
RNF31 for ontologies About GeneDecksing
RNF31 Antibody Products:
Assay Products for RNF31: |
Protein
Domains /
Families
for RNF31 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNF31 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q96EP0ProtoNet protein and cluster: Q96EP0 3 Blocks protein families: IPB001841 Zn-finger IPB001876 Zn-finger IPB002867 Zn-finger
UniProtKB/Swiss-Prot: RNF31_HUMAN, Q96EP0Domain: The RanBP2-type zinc fingers mediate the specific interaction with ubiquitinDomain: The UBA domain mediates association with RBCK1/HOIL1 via interaction with its UBL domainDomain: RING 1 and IBR zinc-fingers catalyze the first step transfer of ubiquitin from the E2 onto RING 2, totransiently form a HECT-like covalent thioester intermediateDomain: The linear ubiquitin chain determining domain (LDD) mediates the final transfer of ubiquitin from RING 2 ontothe N-terminus of a target ubiquitinSimilarity: Contains 1 IBR-type zinc fingerSimilarity: Contains 3 RanBP2-type zinc fingersSimilarity: Contains 2 RING-type zinc fingersSimilarity: Contains 1 UBA domain |
Function
for RNF31 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RNF31_HUMAN, Q96EP0Function: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('M-1'-linked)polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBACconjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and theJNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death andthereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) followingpolyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG andpossibly other components contributing to the stability of the complex. Binds polyubiquitin of different linkage typesEnzyme Number (IUBMB): EC 6.3.2.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RNF31 (NM_017999) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF31 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF31 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF31 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
RNF31 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RNF31:
|
Pathways & Interactions
for RNF31 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF31
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/38 Interacting proteins for RNF31 (Q96EP01, 2, 3 ENSP000003151124) via UniProtKB, MINT, STRING, and/or I2D (see all 38)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000209 | protein polyubiquitination |
IDA | 17006537 | | GO:0023035 | CD40 signaling pathway |
ISS | -- | | GO:0043123 | positive regulation of I-kappaB kinase/NF-kappaB cascade |
IDA | -- | | GO:0050852 | T cell receptor signaling pathway |
IDA | -- | | GO:0051092 | positive regulation of NF-kappaB transcription factor activity |
IDA | 19136968 |
RNF31 for ontologies About GeneDecksing
|
Drugs & Compounds
for RNF31 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RNF31
Search CenterWatch for drugs/clinical trials and news about RNF31
|
Transcripts
for RNF31 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNF31 gene: NM_017999.4 Unigene Cluster for RNF31: Ring finger protein 31 Hs.375217 [show with all ESTs]Unigene Representative Sequence: NM_01799918/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27): ENST00000560875 ENST00000559308 ENST00000558634 ENST00000557878 ENST00000559533
ENST00000557991 ENST00000559117 ENST00000559438 ENST00000560071 ENST00000559275(uc001wml.1)
ENST00000324103(uc001wmm.1 uc001wmn.1 uc010alg.1) ENST00000559882
ENST00000559260 ENST00000491351 ENST00000560342 ENST00000558907 ENST00000560787
ENST00000559583
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RNF31 (NM_017999) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF31 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF31 |
Additional cDNA sequence: AB265810.1 AK000973.1 AK055542.1 AK122711.1 AK225832.1 AK291247.1 AY256461.1 BC009821.2 BC012077.1 BC017376.2 21 DOTS entries: DT.87013010 DT.87016890 DT.312276 DT.100651230 DT.120772567 DT.212225 DT.97818991 DT.97790739 DT.100784299 DT.452108 DT.95306414 DT.100784297 DT.100784302 DT.100665760 DT.100784295 DT.120772530 DT.120772572 DT.120772613 DT.86836532 DT.95323921 DT.87012582 24/410 AceView cDNA sequences (see all 410): BU784065 BM667985 CA305900 BX099826 BG058600 CR609755 CB305470 BC009821 BM825576 CD722080 BF525953 BQ574532 BX506052 BG674505 BQ926737 CR610511 BM782298 CR603020 BC017376 BQ685508 CR602478 AK055542 BQ645370 CA446496
GeneLoc Exon Structure
5/22 Alternative Splicing Database (ASD) splice patterns (SP) for RNF31 (see all 22) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | - | | - | | |
| SP3: | | | | | | | | | | | | | | | | | - | | | | | | - | | | | | | | | | | | | | | - | | - | | | | | | | | | | - | | - | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | |
| ExUns: | 16 | ^ | 17 | ^ | 18a | · | 18b | · | 18c | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | · | 26c | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · | 29b | · | 29c | ^ | 30 | ^ | 31 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 32 | ^ | 33a | · | 33b | · | 33c | ^ | 34a | · | 34b | ^ | 35 | ^ | 36a | · | 36b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for RNF31
|
Expression
for RNF31 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNF31 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCCTGCTCCC
About this image
See RNF31 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF31
SOURCE GeneReport for Unigene cluster: Hs.375217
UniProtKB/Swiss-Prot: RNF31_HUMAN, Q96EP0Tissue specificity: Expressed in both normal and transformed breast epithelial cell lines
SABiosciences Expression via Pathway-Focused PCR Array including RNF31:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF31
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RNF31 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF31 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF31 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF31 |
Orthologs
for RNF31 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for RNF31 gene from 5/16 species (see all 16) About this table
ENSEMBL Gene Tree for RNF31 (if available)
TreeFam Gene Tree for RNF31 (if available) |
Paralogs
for RNF31 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNF31 gene
- ENSG000002595292
RNF31 for paralogs About GeneDecksing
|
Genomic Variants
for RNF31 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RNF31 (24615892 - 24629870 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RNF31
1 Inversion: 37155 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF31 |
|
Disorders
/ Diseases
for RNF31 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RNF31 for disorders About GeneDecksing
OMIM gene information: 612487
OMIM disorders: --
5  diseases for RNF31: About MalaCardsdengue hemorrhagic fever hemorrhagic fever macular degeneration breast cancer
ataxia
2 diseases from the University of Copenhagen DISEASES database for RNF31:CD40 ligand deficiency X-linked hyper IgM syndrome Human Genome Epidemiology (HuGE) Navigator: RNF31 (1 document)
Export disorders for RNF31 gene to outside databases
|
Publications
for RNF31 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNF31 gene, integrated from 9 sources (see all 41):
(articles sorted by number of sources associating them with RNF31) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of the protein Zibra, its genomic organization, regulation, and expression in breast cancer cells. (PubMed id 15093743)1, 2, 9 Thompson H.G.R.... Brody J.P. (2004)
- A non-canonical UBA-UBL interaction forms the linear-u biquitin-chain assembly complex. (PubMed id 22430200)1, 2 Yagi H....Kato K. (2012)
- The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension. (PubMed id 22863777)1, 2 Smit J.J.... Sixma T.K. (2012)
- Involvement of linear polyubiquitylation of NEMO in N F-kappaB activation. (PubMed id 19136968)1, 2 Tokunaga F....Iwai K. (2009)
- Recruitment of the linear ubiquitin chain assembly co mplex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. (PubMed id 20005846)1, 2 Haas T.L....Walczak H. (2009)
- A ubiquitin ligase complex assembles linear polyubiquitin chains. (PubMed id 17006537)1, 2 Kirisako T.... Iwai K. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones. (PubMed id 12693554)1, 2 Jikuya H....Ohara O. (2003)
- TRIADs: a new class of proteins with a novel cysteine-rich signature. (PubMed id 10422847)1, 3 van der Reijden B.A....Jansen J.H. (1999)
|
External Searches for RNF31 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RNF31 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNF31 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNF31 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNF31 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RNF31 gene:
Search GeneIP for patents involving RNF31
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for RNF31 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for RNF31 | | OriGene shRNA RFP for RNF31 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF31 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF31 | | | OriGene Protein Over-expression Lysate for RNF31 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RNF31 | | OriGene 3'-UTR Clone for RNF31 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF31 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for RNF31 | | OriGene Custom Protein Services for RNF31 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNF31 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF31 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF31 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF31 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF31 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF31 |
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| | | | Search Tocris compounds for RNF31 |
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 | | | RNF31 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF31 |
|  |  |  | | | | ThermoFisher Antibodies for RNF31 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF31 |
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