Free for academic non-profit institutions. Other users need a Commercial license

Aliases for RNF26 Gene

Aliases for RNF26 Gene

  • Ring Finger Protein 26 2 3
  • Ring Finger Protein With Leucine Zipper 2

External Ids for RNF26 Gene

Summaries for RNF26 Gene

Entrez Gene Summary for RNF26 Gene

  • The protein encoded by this intronless gene contains a C3HC5 type of RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The expression of this gene was found to be upregulated in cancer cell lines derived from different types of cancer. [provided by RefSeq, Jul 2008]

GeneCards Summary for RNF26 Gene

RNF26 (Ring Finger Protein 26) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF26 Gene

Genomics for RNF26 Gene

Genomic Location for RNF26 Gene

Start:
119,334,500 bp from pter
End:
119,337,314 bp from pter
Size:
2,815 bases
Orientation:
Plus strand

Genomic View for RNF26 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNF26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF26 Gene

Regulatory Elements for RNF26 Gene

Proteins for RNF26 Gene

  • Protein details for RNF26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BY78-RNF26_HUMAN
    Recommended name:
    RING finger protein 26
    Protein Accession:
    Q9BY78
    Secondary Accessions:
    • Q542Y8

    Protein attributes for RNF26 Gene

    Size:
    433 amino acids
    Molecular mass:
    47737 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF26 Gene

Proteomics data for RNF26 Gene at MOPED

Post-translational modifications for RNF26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF26 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF26 Gene

Domains for RNF26 Gene

Gene Families for RNF26 Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers

Protein Domains for RNF26 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

RNF26_HUMAN
Similarity:
  • Contains 1 RING-type zinc finger.:
    • Q9BY78
genes like me logo Genes that share domains with RNF26: view

Function for RNF26 Gene

Gene Ontology (GO) - Molecular Function for RNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding NAS 11352657
genes like me logo Genes that share ontologies with RNF26: view
genes like me logo Genes that share phenotypes with RNF26: view

miRNA for RNF26 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for RNF26 Gene

Localization for RNF26 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF26 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RNF26 Gene COMPARTMENTS Subcellular localization image for RNF26 gene
Compartment Confidence
plasma membrane 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for RNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNF26: view

Pathways for RNF26 Gene

SuperPathways for RNF26 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF26 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with RNF26: view

No data available for Pathways by source for RNF26 Gene

Transcripts for RNF26 Gene

mRNA/cDNA for RNF26 Gene

(1) REFSEQ mRNAs :
(85) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNF26 Gene

No ASD Table

Relevant External Links for RNF26 Gene

GeneLoc Exon Structure for
RNF26
ECgene alternative splicing isoforms for
RNF26

Expression for RNF26 Gene

mRNA expression in normal human tissues for RNF26 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RNF26 Gene

SOURCE GeneReport for Unigene cluster for RNF26 Gene Hs.524084

mRNA Expression by UniProt/SwissProt for RNF26 Gene

Q9BY78-RNF26_HUMAN
Tissue specificity: Ubiquitous. Up-regulated in several cancer cell lines
genes like me logo Genes that share expressions with RNF26: view

Orthologs for RNF26 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RNF26 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RNF26 36
  • 99.69 (n)
  • 99.77 (a)
RNF26 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia RNF26 36
  • 88.76 (n)
  • 90.76 (a)
RNF26 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia RNF26 36
  • 89.22 (n)
  • 90.53 (a)
RNF26 37
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm9008 37
  • 87 (a)
OneToMany
Rnf26 36
  • 84.43 (n)
  • 87.97 (a)
Rnf26 16
Rnf26 37
  • 88 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Rnf26 36
  • 83.73 (n)
  • 86.08 (a)
chicken
(Gallus gallus)
Aves RNF26 36
  • 60.42 (n)
  • 50.69 (a)
RNF26 37
  • 45 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.18835 36
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf26 36
  • 49.44 (n)
  • 41.83 (a)
zebrafish
(Danio rerio)
Actinopterygii Dr.18731 36
rnf26 36
  • 50.84 (n)
  • 39.7 (a)
rnf26 37
  • 37 (a)
OneToOne
Species with no ortholog for RNF26:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF26 Gene

ENSEMBL:
Gene Tree for RNF26 (if available)
TreeFam:
Gene Tree for RNF26 (if available)

Paralogs for RNF26 Gene

No data available for Paralogs for RNF26 Gene

Variants for RNF26 Gene

Sequence variations from dbSNP and Humsavar for RNF26 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs6649 -- 119,337,218(+) AGGGT(C/T)CAAAT utr-variant-3-prime
rs2248853 -- 119,336,736(-) ACAGG(A/G)GTAAC utr-variant-3-prime
rs2248863 -- 119,336,631(-) AGCAT(C/T)GAAGG utr-variant-3-prime
rs2510140 -- 119,334,471(-) CAGCC(A/C)ATCGG upstream-variant-2KB
rs2511841 -- 119,335,665(-) ACGTC(C/T)GTCAT synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for RNF26 Gene

Variant ID Type Subtype PubMed ID
nsv898417 CNV Loss 21882294
nsv898418 CNV Loss 21882294
nsv826103 CNV Gain 20364138
nsv826104 CNV Gain 20364138
nsv522705 CNV Loss 19592680

Relevant External Links for RNF26 Gene

HapMap Linkage Disequilibrium report
RNF26

Disorders for RNF26 Gene

Relevant External Links for RNF26

Genetic Association Database (GAD)
RNF26
Human Genome Epidemiology (HuGE) Navigator
RNF26
genes like me logo Genes that share disorders with RNF26: view

No data available for UniProtKB/Swiss-Prot for RNF26 Gene

Publications for RNF26 Gene

  1. Molecular cloning and characterization of RNF26 on human chromosome 11q23 region, encoding a novel RING finger protein with leucine zipper. (PMID: 11352657) Katoh M. (Biochem. Biophys. Res. Commun. 2001) 2 3 4 23
  2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 49
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4
  5. Identification of host proteins required for HIV infection through a functional genomic screen. (PMID: 18187620) Brass A.L. … Elledge S.J. (Science 2008) 3

Products for RNF26 Gene

Sources for RNF26 Gene

Back to Top

Content