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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNF220 Gene

protein-coding   GIFtS: 51
GCID: GC01P044870

ring finger protein 220

(Previous name: chromosome 1 open reading frame 164 )
(Previous symbol: C1orf164)
 Explore 1 disease affiliated with
RNF220 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for RNF220    

Aliases
for RNF220 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ring Finger Protein 2201 2 3
C1orf1641 2 3
FLJ105971
Chromosome 1 Open Reading Frame 1641
E3 Ubiquitin-Protein Ligase RNF2202
EC 6.3.2.-3

External Ids:    HGNC: 255521   Entrez Gene: 551822   Ensembl: ENSG000001871477   UniProtKB: Q5VTB93   

Export aliases for RNF220 gene to outside databases

Previous GC identifers: GC01P044644 GC01P042984


Summaries
for RNF220 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By
similarity)

Gene Wiki entry for RNF220 (C1orf164)


Genomic Views
for RNF220 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.1  NT_032977.9  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNF220 gene promoter:
         Elk-1   C/EBPbeta   FOXD1   POU6F1 (c2)   POU2F1   POU2F1a   SEF-1 (1)   ZID   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RNF220 promoter sequence
   Search SABiosciences Chromatin IP Primers for RNF220

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF220


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34.1

RNF220 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF220 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P044870:  view genomic region     (about GC identifiers)

Start:
 44,870,866 bp from pter      End:
 45,117,396 bp from pter
Size:
 246,531 bases      Orientation:
 plus strand

Proteins
for RNF220 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF220  
Size: 566 amino acids; 62765 Da
Subunit: Interacts with SIN3B (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAA91704.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B3KPJ3 Q4KMX2 Q9NVP6

Explore the universe of human proteins at neXtProt for RNF220: NX_Q5VTB9

Post-translational modifications:

  • Auto-ubiquitinated; leads to proteasomal degradation (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q5VTB9

    • RNF220 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060620.2  
    ENSEMBL proteins: 
     ENSP00000347548   ENSP00000354872   ENSP00000411541   ENSP00000335580   ENSP00000388533  
     ENSP00000361321   ENSP00000414640  
    Reactome Protein details: Q5VTB9
    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein: RNF220
    OriGene Protein Over-expression Lysate: RNF220
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    GenScript Custom Purified and Recombinant Proteins Services for RNF220
    Novus Biologicals RNF220 Proteins
    Novus Biologicals RNF220 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for RNF220

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--


    RNF220 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for RNF220

    Protein Domains /
    Families
    for RNF220 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    RNF220 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q5VTB9

    ProtoNet protein and cluster: Q5VTB9

    UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
    Similarity: Contains 1 RING-type zinc finger


    Function
    for RNF220 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
    Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By
    similarity)

    Enzyme Number (IUBMB): EC 6.3.2.-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF220
    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF220 (see all 28):
    hsa-miR-3149 hsa-miR-30c hsa-miR-520d-5p hsa-miR-487a hsa-miR-485-3p hsa-miR-30d hsa-miR-181a-2* hsa-miR-218
    SwitchGear 3'UTR luciferase reporter plasmid: RNF220 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF220
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF220

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for RNF220

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for RNF220

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF220

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity ISS--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--


    RNF220 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for RNF220:
     Synthetic lethal with Ras 


    Pathways & Interactions
    for RNF220 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Antigen processing: Ubiquitination & Proteasome degradation
    		Antigen processing: Ubiquitination & Proteasome degradation1.00
    		Polyubiquitination of substrate0.75
    		Class I MHC mediated antigen processing & presentation0.83
    2Immune System
    		Immune System1.00
    		Adaptive Immune System0.59

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5        Reactome Pathways for RNF220
        Antigen processing: Ubiquitination & Proteasome degradation
    Polyubiquitination of substrate
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
    Pathway: Protein modification; protein ubiquitination


    RNF220 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF220

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for RNF220 (Q5VTB92, 3 ENSP000003475484) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930092, 3, ENSP000003435354MINT-2874127 I2D: score=4 STRING: ENSP00000343535
    SIN3BO751823, ENSP000003691314I2D: score=3 STRING: ENSP00000369131
    UBE2WQ96B023, ENSP000003974534I2D: score=1 STRING: ENSP00000397453
    UBE2E1P519653, ENSP000003037094I2D: score=2 STRING: ENSP00000303709
    UBE2E2Q96LR53, ENSP000003799314I2D: score=1 STRING: ENSP00000379931
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination ISS--
    GO:0051865protein autoubiquitination ISS--


    RNF220 for ontologies           About GeneDecksing



    Drugs & Compounds
    for RNF220 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNF220
    Search CenterWatch for drugs/clinical trials and news about RNF220 / RN220 

    Transcripts
    for RNF220 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for RNF220 gene: 
    NM_018150.2  

    Unigene Cluster for RNF220:

    Ring finger protein 220
    Hs.456557  [show with all ESTs]
    Unigene Representative Sequence: AK124790
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000355387 ENST00000361799(uc001clv.1 uc001clw.1) ENST00000487332
    ENST00000470498 ENST00000496262 ENST00000453863 ENST00000335497 ENST00000440132
    ENST00000474064(uc010okz.2 uc001cma.1 uc001clx.2) ENST00000471494
    ENST00000488865 ENST00000497469 ENST00000475378 ENST00000484745 ENST00000474394
    ENST00000480686 ENST00000474956 ENST00000372247(uc010oky.1)

    miRNA
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF220 (see all 28):
    hsa-miR-3149 hsa-miR-30c hsa-miR-520d-5p hsa-miR-487a hsa-miR-485-3p hsa-miR-30d hsa-miR-181a-2* hsa-miR-218
    SwitchGear 3'UTR luciferase reporter plasmid: RNF220 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF220
    OriGene shRNA RFP: RNF220
    OriGene siRNA: RNF220
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF220
    Clone
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    GenScript: all cDNA clones in your preferred vector: RNF220 (NM_018150)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF220
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF220 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF220
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF220

    Additional cDNA sequence: 

    AF151080.1 AK001459.1 AK025744.1 AK056424.1 AK124790.1 AK225180.1 AK293411.1 AK296038.1 
    AK297228.1 BC000279.1 BC034221.1 BC062600.1 BC073835.1 BC098266.1 BC098300.1 BC105790.1 
    BC128534.1 

    24/28 DOTS entries (see all 28):

    DT.100797112  DT.100840037  DT.92438503  DT.100797113  DT.97854211  DT.97774368  DT.92438498  DT.454858 
    DT.92438497  DT.95134795  DT.121353012  DT.121353056  DT.97794134  DT.100028723  DT.100652060  DT.100674085 
    DT.121352914  DT.109248  DT.121352937  DT.75178881  DT.100797118  DT.121352904  DT.121352913  DT.121353002 

    24/402 AceView cDNA sequences (see all 402):

    BQ924538 AA359310 BM723049 AA349758 T35768 BM804293 BE645775 AI637639 
    AL702975 BM677499 CD674990 BX325273 BC062600 BE796901 BU157237 AW438584 
    CB306178 BM799338 BM917230 AA535379 CR594813 BM055342 BQ021262 CA867556 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for RNF220 (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ·
    SP1:        -     -     -     -     -                                   -     -                 -                 -     -                 -                 -   
    SP2:        -     -     -     -     -                                   -     -                 -                 -     -                 -                 -   
    SP3:                                                                                                                                      -                 -   
    SP4:                                                                                                              -     -                 -                     
    SP5:                                                                                                                                                            

    ExUns: 17d ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24
    SP1:  -     -                             -                     
    SP2:  -     -                             -                     
    SP3:  -     -                             -                     
    SP4:                                                            
    SP5:                                      -                     


    ECgene alternative splicing isoforms for RNF220

    Expression
    for RNF220 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNF220 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GATTAAACCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    RNF220 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Intermediate limb mesenchymal cells (ILM cells) (Primary Cell)Bone, Cartilage, Limb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RNF220 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNF220

    SOURCE GeneReport for Unigene cluster: Hs.456557
        SABiosciences Expression via Pathway-Focused PCR Array including RNF220: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    Orthologs
    for RNF220 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for RNF220 gene from 6/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Rnf2201 , 5 ring finger protein 2201, 5 92.23(n)1
    97.88(a)1    		   4 (53.44 cM)5
    667431  NM_025739.21  NP_080015.31 
     1172714635 
    chicken
    (Gallus gallus)    		 Aves RNF2201 ring finger protein 220 83.07(n)
    95.03(a)    		   424580  NM_001109987.1  NP_001103457.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 75(a)
    		 1 ↔ 1
    		 4(109868620-109970443)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.119992 Transcribed sequence with moderate similarity to protein refNP_060620.1 (H.sapiens) hypothetical protein FLJ10597 [Homo sapiens] less 82(n)    142021170 
    zebrafish
    (Danio rerio)    		 Actinopterygii rnf220b1 ring finger protein 220b 66.61(n)
    65.57(a)    		   558091  XM_681262.4  XP_686354.4 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG48131 CG4813 50(n)
    40.3(a)    		   42690  NM_142831.3  NP_651088.1 


    ENSEMBL Gene Tree for RNF220 (if available)
    TreeFam Gene Tree for RNF220 (if available) 

    Paralogs
    for RNF220 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for RNF220 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4232 NCBI SNPs in RNF220 are shown (see all 4232)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 1 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs120827441,2
    		--44868988(+) TAGAGC/GCTAAC 1 -- us2k10--------
    rs1874884411,2
    		--44869059(+) CAGGCA/GTGGTG 1 -- us2k10--------
    rs1919345111,2
    		--44869061(+) GGCGTG/TGTGGC 1 -- us2k10--------
    rs1848021271,2
    		--44869149(+) CCAACA/GTGGTG 1 -- us2k10--------
    rs1488098371,2
    		--44869184(+) TTTGGG/TCATGG 1 -- us2k10--------
    rs1415778411,2
    		--44869239(+) AGAATC/TGCTTG 1 -- us2k10--------
    rs1508941141,2
    		--44869247(+) TTGAAC/TTCGGG 1 -- us2k10--------
    rs1474169011,2
    		C,--44869331(+) AAAAA-/TAAATA 1 -- us2k10--------
    rs1877162561,2
    		--44869586(+) GACAAC/TTTATA 1 -- us2k10--------
    rs1393677111,2
    		--44869843(+) GATTAC/TAGGCG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RNF220 (44870866 - 45117396 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for RNF220
         1 CNV: 4221
         1 Indel: 63658

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    Disorders / Diseases
    for RNF220 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    RNF220 for disorders           About GeneDecksing

    1 disease for RNF220:    About MalaCards
    ataxia

    Human Genome Epidemiology (HuGE) Navigator: RNF220 (4 documents)

    Export disorders for RNF220 gene to outside databases

    Publications
    for RNF220 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNF220 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with RNF220)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (2000)
    5. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)

    External Searches for RNF220 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    Genome Databases showing RNF220 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55182 HGNC: 25552 AceView: FLJ10597 Ensembl:ENSG00000187147 euGenes: HUgn55182
    ECgene: RNF220 H-InvDB: RNF220

    Other Databases showing RNF220 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing RNF220 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNF220 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for RNF220 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for RNF220 gene:
    Search GeneIP for patents involving RNF220

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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