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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNF220 Gene

protein-coding   GIFtS: 48
GCID: GC01P044870

Ring Finger Protein 220

(Previous name: chromosome 1 open reading frame 164)
(Previous symbol: C1orf164)
  Search for RNF220
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ring Finger Protein 2201 2 3
C1orf1641 2 3
Chromosome 1 Open Reading Frame 1641
E3 Ubiquitin-Protein Ligase RNF2202
EC 6.3.2.-3

External Ids:    HGNC: 255521   Entrez Gene: 551822   Ensembl: ENSG000001871477   UniProtKB: Q5VTB93   

Export aliases for RNF220 gene to outside databases

Previous GC identifers: GC01P044644 GC01P042984


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for RNF220 Gene: 
RNF220 (ring finger protein 220) is a protein-coding gene. Among its related super-pathways are Class I MHC mediated antigen processing & presentation and Immune System. GO annotations related to this gene include ubiquitin-protein ligase activity and zinc ion binding.

UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By
similarity)

Gene Wiki entry for RNF220 (C1orf164) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNF220 gene promoter:
         Elk-1   C/EBPbeta   FOXD1   POU6F1 (c2)   POU2F1   POU2F1a   SEF-1 (1)   ZID   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNF220 promoter sequence
   Search SABiosciences Chromatin IP Primers for RNF220

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF220


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.1   Ensembl cytogenetic band:  1p34.1   HGNC cytogenetic band: 1p34.1

RNF220 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF220 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P044870:  view genomic region     (about GC identifiers)

Start:
44,870,866 bp from pter      End:
45,117,396 bp from pter
Size:
246,531 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF220  
Size: 566 amino acids; 62765 Da
Subunit: Interacts with SIN3B (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAA91704.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B3KPJ3 Q4KMX2 Q9NVP6

Explore the universe of human proteins at neXtProt for RNF220: NX_Q5VTB9

Explore proteomics data for RNF220 at MOPED 

Post-translational modifications:

  • UniProtKB: Auto-ubiquitinated; leads to proteasomal degradation (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5VTB9

  • RNF220 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RNF220 Protein Expression
    REFSEQ proteins: NP_060620.2  
    ENSEMBL proteins: 
     ENSP00000347548   ENSP00000354872   ENSP00000411541   ENSP00000335580   ENSP00000388533  
     ENSP00000475383   ENSP00000361321   ENSP00000414640  
    Reactome Protein details: Q5VTB9
    Human Recombinant Protein Products for RNF220: 
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    OriGene Purified Protein for RNF220
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    Novus Biologicals RNF220 Proteins
    Novus Biologicals RNF220 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RNF220 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--

    RNF220 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for RNF220 
    Cloud-Clone Corp. CLIAs for RNF220


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers

    2 InterPro protein domains:
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q5VTB9

    ProtoNet protein and cluster: Q5VTB9

    UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
    Similarity: Contains 1 RING-type zinc finger


    RNF220 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RN220_HUMAN, Q5VTB9
    Function: E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B (By
    similarity)

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity ISS--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    RNF220 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RNF220:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for RNF220 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for RNF220

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RNF220 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RNF220 

    miRNA
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF220 (see all 28):
    hsa-miR-3149 hsa-miR-30c hsa-miR-520d-5p hsa-miR-487a hsa-miR-485-3p hsa-miR-30d hsa-miR-181a-2* hsa-miR-218
    SwitchGear 3'UTR luciferase reporter plasmidRNF220 3' UTR sequence
    Inhib. RNA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF220


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RNF220 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation0.83
    Class I MHC mediated antigen processing & presentation0.83
    2Immune System
    Immune System0.56
    Adaptive Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for RNF220
        Antigen processing: Ubiquitination & Proteasome degradation
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    UniProtKB/Swiss-Prot: RN220_HUMAN, Q5VTB9
    Pathway: Protein modification; protein ubiquitination


    RNF220 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF220

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for RNF220 (Q5VTB92, 3 ENSP000003475484) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930092, 3, ENSP000003435354MINT-2874127 I2D: score=4 STRING: ENSP00000343535
    SIN3BO751823, ENSP000003691314I2D: score=3 STRING: ENSP00000369131
    UBE2WQ96B023, ENSP000003974534I2D: score=1 STRING: ENSP00000397453
    UBE2E1P519653, ENSP000003037094I2D: score=2 STRING: ENSP00000303709
    UBE2E2Q96LR53, ENSP000003799314I2D: score=1 STRING: ENSP00000379931
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination ISS--
    GO:0051865protein autoubiquitination ISS--

    RNF220 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNF220 (RN220)

    Search CenterWatch for drugs/clinical trials and news about RNF220 / RN220

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RNF220 gene: 
    NM_018150.2  

    Unigene Cluster for RNF220:

    Ring finger protein 220
    Hs.456557  [show with all ESTs]
    Unigene Representative Sequence: AK124790
    18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000355387 ENST00000361799(uc001clv.1 uc001clw.1) ENST00000487332
    ENST00000470498 ENST00000496262 ENST00000453863 ENST00000335497 ENST00000440132
    ENST00000474064(uc010okz.2 uc001cma.1 uc001clx.2) ENST00000471494
    ENST00000488865 ENST00000497469 ENST00000475378 ENST00000484745 ENST00000474394
    ENST00000480686 ENST00000474956 ENST00000372247(uc010oky.1)
    miRNA
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    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF220 (see all 28):
    hsa-miR-3149 hsa-miR-30c hsa-miR-520d-5p hsa-miR-487a hsa-miR-485-3p hsa-miR-30d hsa-miR-181a-2* hsa-miR-218
    SwitchGear 3'UTR luciferase reporter plasmidRNF220 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF220
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF220
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF220
    Sirion Biotech Customized lentivirus for stable overexpression of RNF220 
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    OriGene qPCR primer pairs and template standards for RNF220
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF220
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF220

    Additional mRNA sequence: 

    AF151080.1 AK001459.1 AK025744.1 AK056424.1 AK124790.1 AK225180.1 AK293411.1 AK296038.1 
    AK297228.1 BC000279.1 BC034221.1 BC062600.1 BC073835.1 BC098266.1 BC098300.1 BC105790.1 
    BC128534.1 

    24/28 DOTS entries (see all 28):

    DT.100797112  DT.100840037  DT.92438503  DT.100797113  DT.97854211  DT.97774368  DT.92438498  DT.454858 
    DT.92438497  DT.95134795  DT.121353012  DT.121353056  DT.97794134  DT.100028723  DT.100652060  DT.100674085 
    DT.121352914  DT.109248  DT.121352937  DT.75178881  DT.100797118  DT.121352904  DT.121352913  DT.121353002 

    24/402 AceView cDNA sequences (see all 402):

    BQ924538 BC034221 CR604881 BM793846 BF970497 BU154020 AI655446 T33117 
    CR618869 CD675916 BI862139 BI768029 AW593185 BQ673859 BI766670 BQ276399 
    BG773834 AI346571 BM761254 NM_018150 BX360392 AW250022 BE791061 AW611878 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for RNF220 (see all 14)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b ^ 17a · 17b · 17c ·
    SP1:        -     -     -     -     -                                   -     -                 -                 -     -                 -                 -   
    SP2:        -     -     -     -     -                                   -     -                 -                 -     -                 -                 -   
    SP3:                                                                                                                                      -                 -   
    SP4:                                                                                                              -     -                 -                     
    SP5:                                                                                                                                                            

    ExUns: 17d ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23 ^ 24
    SP1:  -     -                             -                     
    SP2:  -     -                             -                     
    SP3:  -     -                             -                     
    SP4:                                                            
    SP5:                                      -                     


    ECgene alternative splicing isoforms for RNF220

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNF220 expression in normal human tissues (normalized intensities)      RNF220 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATTAAACCA
    RNF220 Expression
    About this image


    RNF220 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Brain (Nervous System)
             Myelinating Oligodendrocyte Cells Forebrain White Matter

    See RNF220 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNF220

    SOURCE GeneReport for Unigene cluster: Hs.456557
        SABiosciences Expression via Pathway-Focused PCR Array including RNF220: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RNF220 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnf2201 , 5 ring finger protein 2201, 5 92.23(n)1
    97.88(a)1
      4 (53.44 cM)5
    667431  NM_025739.21  NP_080015.31 
     1172714635 
    chicken
    (Gallus gallus)
    Aves RNF2201 ring finger protein 220 83.07(n)
    95.03(a)
      424580  NM_001109987.1  NP_001103457.1 
    lizard
    (Anolis carolinensis)
    Reptilia RNF2206
    --
    Uncharacterized protein
    95(a)
    75(a)
    many → 1
    many → 1
    4(109620012-109620641)
    4(109868620-109970448)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.119992 Transcribed sequence with moderate similarity to protein more 82(n)    142021170 
    zebrafish
    (Danio rerio)
    Actinopterygii rnf220b1 ring finger protein 220b 66.61(n)
    65.57(a)
      558091  XM_681262.4  XP_686354.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG48131 CG4813 50(n)
    40.3(a)
      42690  NM_142831.3  NP_651088.1 


    ENSEMBL Gene Tree for RNF220 (if available)
    TreeFam Gene Tree for RNF220 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4966 SNPs in RNF220 are shown (see all 4966)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs3701809431,2
    C--43012111(+) CTTTT-/CTTTTTT 1 -- int11Minor allele frequency- CT:0.00NA 2
    rs120827441,2
    --44868988(+) TAGAGC/GCTAAC 1 -- us2k10--------
    rs1874884411,2
    C--44869059(+) CAGGCA/GTGGTG 1 -- us2k10--------
    rs1919345111,2
    C--44869061(+) GGCGTG/TGTGGC 1 -- us2k10--------
    rs1848021271,2
    --44869149(+) CCAACA/GTGGTG 1 -- us2k10--------
    rs1488098371,2
    C--44869184(+) TTTGGG/TCATGG 1 -- us2k10--------
    rs1415778411,2
    C--44869239(+) AGAATC/TGCTTG 1 -- us2k10--------
    rs1508941141,2
    --44869247(+) TTGAAC/TTCGGG 1 -- us2k10--------
    rs1474169011,2
    C--44869331(+) AAAAA-/TAAATA 1 -- us2k10--------
    rs1877162561,2
    --44869586(+) GACAAC/TTTATA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for RNF220 (44870866 - 45117396 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for RNF220 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2747741CNV Deletion23290073
    dgv41e199CNV Deletion23128226
    esv1005212CNV Deletion20482838
    esv2747730CNV Deletion23290073
    esv2747719CNV Deletion23290073
    esv2747708CNV Deletion23290073
    esv272636CNV Insertion20981092
    esv1001605CNV Insertion20482838
    esv267525CNV Insertion20981092
    nsv744CNV Insertion18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RNF220 for disorders           About MalaCards

    RNF220 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RNF220
    Human Genome Epidemiology (HuGE) Navigator: RNF220 (4 documents)

    Export disorders for RNF220 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNF220 gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with RNF220)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (2000)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55182 HGNC: 25552 AceView: FLJ10597 Ensembl:ENSG00000187147 euGenes: HUgn55182
    ECgene: RNF220 H-InvDB: RNF220

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNF220 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RNF220 gene:
    Search GeneIP for patents involving RNF220

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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