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Aliases for RNF217-AS1 Gene

Subcategory (RNA class) for RNF217-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for RNF217-AS1 Gene

  • RNF217 Antisense RNA 1 (Head To Head) 2 3 5
  • Six-Twelve Leukemia 2 3
  • STL 3

External Ids for RNF217-AS1 Gene

Summaries for RNF217-AS1 Gene

GeneCards Summary for RNF217-AS1 Gene

RNF217-AS1 (RNF217 Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with RNF217-AS1 include Peroneal Neuropathy and Leber Congenital Amaurosis.

Additional gene information for RNF217-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF217-AS1 Gene

Genomics for RNF217-AS1 Gene

Regulatory Elements for RNF217-AS1 Gene

Enhancers for RNF217-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06H125013 1.5 FANTOM5 Ensembl ENCODE 29.1 -51.2 -51161 2 ATF1 FEZF1 ZNF2 ZNF766 ELK1 ZNF548 ATF7 YY2 ZNF488 ZNF662 TRMT11 RNF217 RNF217-AS1 GC06P125084
GH06H125810 1.6 Ensembl ENCODE dbSUPER 19.9 -849.2 -849192 2 PKNOX1 FEZF1 ZNF2 ZNF302 FOS SP3 JUNB REST SMARCB1 SMARCA4 TRMT11 RNF217-AS1 NCOA7-AS1 NCOA7
GH06H124983 1 Ensembl ENCODE 27.1 -21.6 -21570 1 SMARCE1 JUN NR2F1 MAFG USF2 ZNF507 JUND ZNF316 IKZF1 NFE2 RNF217 RNF217-AS1 GC06P125084
GH06H125779 1.7 Ensembl ENCODE dbSUPER 12.5 -818.5 -818459 3 HNRNPUL1 PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 HEY2 CENPW RNF217 TRMT11 RNF217-AS1 NCOA7 NCOA7-AS1
GH06H124960 1.6 FANTOM5 Ensembl ENCODE 10.5 -0.6 -592 6 HDGF FOXA2 ARNT SIN3A ZNF2 YY1 FOS SP3 REST SMARCB1 RNF217 RNF217-AS1 GC06P125084
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNF217-AS1 on UCSC Golden Path with GeneCards custom track

Promoters for RNF217-AS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000202144 -61 3401 HDGF FOXA2 FEZF1 ZNF2 YY1 SP3 REST ZNF592 ZNF610 SMARCA4

Genomic Location for RNF217-AS1 Gene

Chromosome:
6
Start:
124,908,243 bp from pter
End:
124,963,039 bp from pter
Size:
54,797 bases
Orientation:
Minus strand

Genomic View for RNF217-AS1 Gene

Genes around RNF217-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF217-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF217-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF217-AS1 Gene

Proteins for RNF217-AS1 Gene

Post-translational modifications for RNF217-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RNF217-AS1 Gene

Domains & Families for RNF217-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for RNF217-AS1 Gene

Function for RNF217-AS1 Gene

Phenotypes From GWAS Catalog for RNF217-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF217-AS1 Gene

Localization for RNF217-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNF217-AS1 gene
Compartment Confidence
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for RNF217-AS1 Gene

Pathways & Interactions for RNF217-AS1 Gene

SuperPathways for RNF217-AS1 Gene

No Data Available

Interacting Proteins for RNF217-AS1 Gene

Gene Ontology (GO) - Biological Process for RNF217-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNF217-AS1 Gene

Drugs & Compounds for RNF217-AS1 Gene

No Compound Related Data Available

Transcripts for RNF217-AS1 Gene

mRNA/cDNA for RNF217-AS1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for RNF217-AS1 Gene

No ASD Table

Relevant External Links for RNF217-AS1 Gene

GeneLoc Exon Structure for
RNF217-AS1
ECgene alternative splicing isoforms for
RNF217-AS1

Expression for RNF217-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNF217-AS1 Gene

genes like me logo Genes that share expression patterns with RNF217-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF217-AS1 Gene

Orthologs for RNF217-AS1 Gene

Evolution for RNF217-AS1 Gene

ENSEMBL:
Gene Tree for RNF217-AS1 (if available)
TreeFam:
Gene Tree for RNF217-AS1 (if available)

No data available for Orthologs for RNF217-AS1 Gene

Paralogs for RNF217-AS1 Gene

No data available for Paralogs for RNF217-AS1 Gene

Variants for RNF217-AS1 Gene

Sequence variations from dbSNP and Humsavar for RNF217-AS1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000051066 -- 124,926,005(+) TAGCA(G/T)CATAT intron-variant
rs1000080489 -- 124,925,548(+) TGATA(C/T)GGTAA intron-variant
rs1000088924 -- 124,921,586(+) CTCCA(A/G)GTCTC intron-variant
rs1000117343 -- 124,916,310(+) AGAAC(A/G)GCAGA intron-variant
rs1000170089 -- 124,946,492(+) AGTAT(A/G)CTTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RNF217-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv1829e212 CNV gain 25503493
esv275592 CNV gain+loss 21479260
nsv1029255 CNV gain 25217958

Relevant External Links for RNF217-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNF217-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for RNF217-AS1 Gene

Disorders for RNF217-AS1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for RNF217-AS1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
peroneal neuropathy
  • peroneal neuropathies
leber congenital amaurosis
  • lca
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for RNF217-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNF217-AS1
genes like me logo Genes that share disorders with RNF217-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RNF217-AS1 Gene

Publications for RNF217-AS1 Gene

  1. A t(6;12)(q23;p13) results in the fusion of ETV6 to a novel gene, STL, in a B-cell ALL cell line. (PMID: 9087565) Suto Y … Bohlander SK (Genes, chromosomes & cancer 1997) 2 3 22 60
  2. Identification and characterization of OSTL (RNF217) encoding a RING-IBR-RING protein adjacent to a translocation breakpoint involving ETV6 in childhood ALL. (PMID: 25298122) Fontanari Krause LM … Bohlander SK (Scientific reports 2014) 3 60
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60

Products for RNF217-AS1 Gene

Sources for RNF217-AS1 Gene

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