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RNF216 Gene

protein-coding GIFtS: 47

GC07M005627

ring finger protein 216
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 6.3.2.- ^³
TRIAD3 ^¹, ², ³
U7I1 ^¹, ²
UBCE7IP1 ^¹, ², ³
ZIN ^¹, ², ³

Descriptions
Triad domain-containing protein 3 ^³
Ubiquitin-conjugating enzyme 7-interacting protein 1 ^³
Zinc finger protein inhibiting NF-kappa-B ^³
ring finger protein 216 ^², ³
ubiquitin conjugating enzyme 7 interacting protein 1 ^²

External Ids
HGNC: 21698¹
Entrez Gene: 54476²
UniProtKB: Q9NWF9³
Ensembl: ENSG00000011275⁷

Search outside databases for aliases for RNF216 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for RNF216:

This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the

serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the

encoded protein are required for its interaction with RIP and for inhibition of TNF- and

IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3

ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and

transfers it to substrates. Several alternatively spliced transcript variants have been described

for this locus but the full-length natures of only some are known. [provided by RefSeq]

UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9

Function: Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2

ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by

the proteasome. Promotes degradation of TLR4 amd TLR9. Isoform 3/ZIN inhibits TNF and IL-1

mediated activation of NF-kappa-B. Promotes TNF and RIP mediated apoptosis

Gene Wiki entry for RNF216

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p22.1 Ensembl cytogenetic band: 7p22.1 HGNC cytogenetic band: 7p22.1

RNF216 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M005627: (about GC identifiers)

Start:	5,626,204 bp from pter
End:	5,787,818 bp from pter
Size:	161,615 bases
Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 5,706,023-5,867,637

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9 (See protein sequence)

Recommended Name: E3 ubiquitin-protein ligase RNF216

Size: 866 amino acids; 99406 Da

Subunit: Interacts with UBE2L3 and to some extent with UBE2L6. Interacts with TLR3, TLR4, TLR5 and

TLR9. Isoform 3/ZIN binds RIPK1 and HIV VIF

Subcellular location: Cytoplasm

Secondary accessions: Q6Y691 Q75ML7 Q7Z2H7 Q7Z7C1 Q8NHW7 Q9NYT1

Alternative splicing: 3 isoforms: Q9NWF9-2 Q9NWF9-1 Q9NWF9-3

Post-translational modifications:

Auto-ubiquitinated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_996994.1 NP_996999.1

ENSEMBL proteins:

ENSP00000374552 ENSP00000374550

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
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	Recombinant Proteins from Abcam (TRIAD3)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	11256614
GO:0005737	cytoplasm	IEA	--

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Antibodies for RNF216:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for RNF216
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (TRIAD3), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibody for RNF216

Assays for RNF216:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NWF9

ProtoNet protein and cluster: Q9NWF9

2 Blocks protein families:

IPB001841 Zn-finger

IPB002867 Zn-finger

UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9

Domain: The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme (By

similarity)

Similarity: Contains 1 IBR-type zinc finger

Similarity: Contains 2 RING-type zinc fingers

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RNF216)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_207111

Applied Biosystems Silencer® siRNAs for RNF216

Sigma-Aldrich siRNA and siRNA Panels for RNF216

Sigma-Aldrich shRNA Panels and shRNA for RNF216

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_207111
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_207111
untagged cDNA clones in CMV expression vector (see all 5): BC004947

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_207111

UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9

Function: Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2

ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by

the proteasome. Promotes degradation of TLR4 amd TLR9. Isoform 3/ZIN inhibits TNF and IL-1

mediated activation of NF-kappa-B. Promotes TNF and RIP mediated apoptosis

Enzyme Number (IUBMB): EC 6.3.2.-

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	15367624
GO:0008270	zinc ion binding	IEA	--
GO:0016874	ligase activity	IEA	--
GO:0046872	metal ion binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9

Pathway: Protein modification; protein ubiquitination

3 Interacting proteins for RNF216 (Q9NWF9^{1, 2}) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
vif vif (xeno)	P12504¹	EBI-723337, EBI-779991
RNF11	Q9Y3C5²	MINT-60865
RNF216	Q9NWF9²	MINT-65649

About this table
3 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptosis IEA --
GO:0019941 modification-dependent protein catabolic process IEA --
GO:0044419 interspecies interaction between organisms IEA --
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for RNF216

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (RNF216)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_207111

Sigma-Aldrich siRNA and siRNA Panels for RNF216

Sigma-Aldrich shRNA Panels and shRNA for RNF216

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_207111 NM_207116

REFSEQ mRNAs for RNF216 gene (2 alternative transcripts):

NM_207111.2 NM_207116.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_207111 NM_207116

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_207111
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_207111
                                 untagged cDNA clones in CMV expression vector (see all 5): BC004947

Additional cDNA sequence: AK128551.1

17 DOTS entries:

DT.100822416 DT.95119108 DT.101984488 DT.100822412 DT.97839502 DT.95094785 DT.121115404 DT.40129927

DT.101971951 DT.97811158 DT.100009747 DT.100717603 DT.75102250 DT.91757544 DT.92048653 DT.95226826

DT.121115379

24/329 AceView cDNA sequences (see all 329 ):

BU785403 BQ212689 CR619754 AA746299 AI380539 AA912708 AI223829 BM817557

BE303029 AA732600 BE350347 NM_021163 BX097482 AI024759 F11246 BG941068

AA804883 AI018503 BU187037 CK429258 AI468075 AI916761 AA278262 AI024605

Unigene Clusters for RNF216:

Ring finger protein 216

Hs.487458 [show with all ESTs], Hs.689456 [show with all ESTs]

Unigene Representative Sequences: NM_207111, AK128551

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for RNF216 (see all 10 )

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7a	·	7b	·	7c	·	7d	^	8a	·	8b	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15	^	16	^	17a	·	17b	^	18	^	19	^	20	^
SP1:													-								-				-
SP2:																																							-		-						-
SP3:
SP4:			-		-		-
SP5:

ExUns:	21a	·	21b
SP1:
SP2:
SP3:
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for RNF216

2 Ensembl transcripts including schematic representations:

ENST00000389902 ENST00000389900

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

RNF216 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for RNF216

¹ / ²

11 probe-sets matching RNF216 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
61970_at²	U95-C	1	1.00	1.00	0.42	1.02	--	--	--	--	--
54606_at²	U95-B	1	1.00	1.00	0.70	1.29	--	--	--	--	--
37476_at²	U95-A	3	0.94	0.41	0.73	0.27	--	--	--	--	--
37477_at²	U95-A	1	0.81	1.00	-0.60	0.21	--	--	--	--	--
48511_at²	U95-B	1	0.69	1.00	0.87	1.48	--	--	--	--	--
218426_s_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
227065_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
218425_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
218426_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
227065_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
218425_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks RNF216 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene clusters: Hs.487458 Hs.689456
UniProtKB/Swiss-Prot: RN216_HUMAN, Q9NWF9
Tissue specificity: Ubiquitous, with the highest levels of expression in testis and peripheral
blood leukocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for RNF216 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	RNF216¹	--	ring finger protein 216	91.4(n) 93.82(a)	479760 XM_536887.2 XP_536887.2
chimpanzee (Pan troglodytes)	RNF216¹	--	ring finger protein 216	99.64(n) 99.78(a)	463248 XM_518955.2 XP_518955.2
cow (Bos taurus)	RNF216¹	--	ring finger protein 216	87.5(n) 88.66(a)	534455 XM_883230.2 XP_888323.1
rat (Rattus norvegicus)	Rnf216¹	--	ring finger protein 216	86.4(n) 86.57(a)	304294 XM_221922.4 XP_221922.4
mouse (Mus musculus)	Rnf216^{1, 5}	5⁵	ring finger protein 216^{1, 5}	86.13(n)¹ 86.99(a)¹	108086¹ NM_080561.3¹ NP_542128.2¹ AF361000⁵ AI647468⁵ (see all 30)

About this table Species with no ortholog for RNF216

ENSEMBL Gene Tree for RNF216

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for RNF216 gene

RNF216L²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/956 NCBI SNPs in RNF216 are shown (see all 956 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 208)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs852442^1,2	A,C,F,H	5626583(-)	`TCTTCA/TGACCA`	2	--	ut3¹		5	MN EU EA WA	600
	rs852438^1,2	A,C,F,H	5627937(-)	`CTAGCG/CGTGCC`	2	--	ut3¹		8	MN EU EA WA NA	744
	rs11974054^1,2	C,F,H	5626714(+)	`CCCCCG/ATGCCT`	2	--	ut3¹		3	EA WA	296
	rs13241373^1,2	C,F,H	5789747(+)	`agtgtC/Tccttc`	2	--	ng3¹ trp³		4	EU EA WA	412
	rs852443^1,2	C,F,H	5625911(-)	`TTCTTT/CTGCAG`	2	--	ng5¹		4	EU EA WA	410
--	rs852439^1,2	A,F,H	5627554(-)	`gaggcG/Aggcgg`	2	--	ut3¹		4	EU EA WA	410
--	rs3857756^1,2	C,F,H	5767295(-)	`TTCAGC/TTCTTT`	2	--	ut5¹		4	EU EA WA	418
	rs852441^1,2	C,F,H	5627212(-)	`TGCTAT/CGTCCT`	2	--	ut3¹		9	MN EU EA WA	1020
--	rs4724729^1,2	F,H	5788613(+)	`GGCTCA/GTGTCC`	2	--	ng3¹		4	EU EA WA	412
--	rs852440^1,2	A	5627460(-)	`caggtA/Gctcag`	2	--	ut3¹		3	NA EA	252

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HapMap Linkage Disequilibrium images for RNF216 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 609948

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/21 PubMed articles for RNF216 gene (see all 21 ):

Ring finger protein ZIN interacts with human immunodeficiency virus type 1 Vif. (PubMed id 15367624)^{1, 3, 4} Feng F.... Li P. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
Triad3A, an E3 ubiquitin-protein ligase regulating Toll-like receptors. (PubMed id 15107846)^{3, 4} Chuang T.-H. and Ulevitch R.J. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
A novel zinc finger protein interacts with receptor-interacting protein (RIP) and inhibits tumor necrosis factor (TNF)- and IL1- induced NF-kappa B activation. (PubMed id 11854271)^{3, 4} Chen D.... Shu H.-B. (2002)
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS Spectra. (PubMed id 17924679)⁴ Yu L.-R.... Veenstra T.D. (2007)
The full-ORF clone resource of the German cDNA Consortium. (PubMed id 17974005)⁴ Bechtel S....Schupp I. (2007)
Triad3A regulates ubiquitination and proteasomal degradation of RIP1 following disruption of Hsp90 binding. (PubMed id 16968706)³ Fearns C....Chuang T.H. (2006)
The LIFEdb database in 2006. (PubMed id 16381901)³ Mehrle A....Wiemann S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 54476	HGNC: 21698	AceView: RBAK	Ensembl:ENSG00000011275	euGenes: HUgn54476
ECgene: RNF216	H-InvDB: RNF216

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for RNF216
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for RNF216:

TaqMan ® Gene Expression Assays

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Free SNP selection tool

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RNF216 Gene

protein-coding GIFtS: 47

Aliases &
Descriptions
for RNF216

Summaries
for RNF216

Genomic Location
for RNF216

Proteins
for RNF216

Protein Domains/
Families
for RNF216

Gene Function
for RNF216

Pathways & Interactions
for RNF216

Drugs & Compounds
for RNF216

Transcripts
for RNF216

Expression
for RNF216

Orthologs
for RNF216

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SNPs/Variants
for RNF216

Disorders & Mutations
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Medical News
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for RNF216

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Genome Databases showing RNF216

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

RNF216 Gene

protein-coding GIFtS: 47

Aliases & Descriptionsfor RNF216

Summariesfor RNF216

Genomic Locationfor RNF216

Proteinsfor RNF216

Protein Domains/Familiesfor RNF216

Gene Functionfor RNF216

Pathways & Interactionsfor RNF216

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for RNF216

Summaries
for RNF216

Genomic Location
for RNF216

Proteins
for RNF216

Protein Domains/
Families
for RNF216

Gene Function
for RNF216

Pathways & Interactions
for RNF216

Drugs & Compounds
for RNF216

Transcripts
for RNF216

Expression
for RNF216

Orthologs
for RNF216

Paralogs
for RNF216

SNPs/Variants
for RNF216

Disorders & Mutations
for RNF216

Medical News
for RNF216

Publications
for RNF216

Licensable Technologies
for RNF216

Services
for RNF216