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Aliases for RNF212B Gene

Aliases for RNF212B Gene

  • Ring Finger Protein 212B 2 3 5
  • C14orf164 3 4
  • Chromosome 14 Open Reading Frame 164 2
  • RING Finger Protein C14orf164-Like 3
  • RING Finger Protein C14orf164 3

External Ids for RNF212B Gene

Previous HGNC Symbols for RNF212B Gene

  • C14orf164

Previous GeneCards Identifiers for RNF212B Gene

  • GC14P023395
  • GC14P023560
  • GC14P023674
  • GC14P023797

Summaries for RNF212B Gene

GeneCards Summary for RNF212B Gene

RNF212B (Ring Finger Protein 212B) is a Protein Coding gene. An important paralog of this gene is RNF212.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF212B Gene

Genomics for RNF212B Gene

Regulatory Elements for RNF212B Gene

Enhancers for RNF212B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F023206 0.4 ENCODE 12.4 +21.2 21201 0.3 RNF212B SLC7A8 CEBPE MIR208B SLC22A17 ACIN1 MYH6 BCL2L2 HOMEZ PPP1R3E
GH14F023207 0.2 ENCODE 12.4 +22.3 22338 1.4 SMARCA4 RNF2 PBX2 RNF212B SLC7A8 CEBPE MIR208B SLC22A17 ACIN1 MYH6 BCL2L2 HOMEZ PPP1R3E
GH14F023145 0.9 FANTOM5 Ensembl ENCODE 11.6 -38.8 -38765 2.8 PKNOX1 ATF1 ARNT YBX1 ZNF2 ELK1 GATA2 NCOA1 REST ZNF518A RNF212B SLC7A8 CEBPE ACIN1 SLC22A17 C14orf93 DHRS4 RNU6-1138P
GH14F023148 0.2 ENCODE 11.6 -36.4 -36406 0.8 SOX13 ZFP64 ZNF644 ZSCAN9 KMT2B TEAD3 RARA NR2F6 MIXL1 GATAD2A SLC7A8 RNF212B CEBPE ACIN1 SLC22A17 IL25 CMTM5 C14orf93 RNU6-1138P
GH14F023140 0.7 FANTOM5 ENCODE 11.6 -43.3 -43261 2.9 ZFP64 ARID4B DMAP1 ZNF48 ZNF121 SLC30A9 ZNF143 MXD4 ZHX2 MIER2 SLC7A8 RNF212B CEBPE ACIN1 SLC22A17 C14orf93 CMTM5 IL25 DHRS4-AS1 RNU6-1138P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around RNF212B on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF212B Gene

23,185,316 bp from pter
23,274,285 bp from pter
88,970 bases
Plus strand

Genomic View for RNF212B Gene

Genes around RNF212B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF212B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF212B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF212B Gene

Proteins for RNF212B Gene

  • Protein details for RNF212B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 212B
    Protein Accession:

    Protein attributes for RNF212B Gene

    300 amino acids
    Molecular mass:
    33570 Da
    Quaternary structure:
    No Data Available
    • Sequence=EB710205; Type=Frameshift; Positions=40; Evidence={ECO:0000305};

neXtProt entry for RNF212B Gene

Post-translational modifications for RNF212B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RNF212B Gene

Domains & Families for RNF212B Gene

Gene Families for RNF212B Gene

Protein Domains for RNF212B Gene

Suggested Antigen Peptide Sequences for RNF212B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 RING-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF212B: view

Function for RNF212B Gene

Gene Ontology (GO) - Molecular Function for RNF212B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019789 SUMO transferase activity IBA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF212B: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF212B Gene

Localization for RNF212B Gene

Gene Ontology (GO) - Cellular Components for RNF212B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000795 synaptonemal complex IBA --
genes like me logo Genes that share ontologies with RNF212B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for RNF212B Gene

Pathways & Interactions for RNF212B Gene

SuperPathways for RNF212B Gene

No Data Available

Interacting Proteins for RNF212B Gene

Gene Ontology (GO) - Biological Process for RNF212B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007129 synapsis IBA --
GO:0016925 protein sumoylation IBA --
genes like me logo Genes that share ontologies with RNF212B: view

No data available for Pathways by source and SIGNOR curated interactions for RNF212B Gene

Transcripts for RNF212B Gene

mRNA/cDNA for RNF212B Gene

(12) REFSEQ mRNAs :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF212B Gene

No ASD Table

Relevant External Links for RNF212B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF212B Gene

mRNA expression in normal human tissues for RNF212B Gene

NURSA nuclear receptor signaling pathways regulating expression of RNF212B Gene:

genes like me logo Genes that share expression patterns with RNF212B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for RNF212B Gene

Orthologs for RNF212B Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF212B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C14H14orf164 34
  • 99.44 (n)
C14orf164 35
  • 99 (a)
(Canis familiaris)
Mammalia C8H14orf164 34
  • 89.52 (n)
C14orf164 35
  • 85 (a)
(Bos Taurus)
Mammalia C10H14orf164 34
  • 88.85 (n)
C14orf164 35
  • 84 (a)
(Rattus norvegicus)
Mammalia LOC102550789 34
  • 85.07 (n)
(Mus musculus)
Mammalia LOC102632837 34
  • 84.85 (n)
Rnf212b 16
(Monodelphis domestica)
Mammalia C14orf164 35
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia C14orf164 35
  • 70 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101735053 34
  • 58.37 (n)
(Danio rerio)
Actinopterygii C2H14orf164 35
  • 36 (a)
(Caenorhabditis elegans)
Secernentea D1081.9 35
  • 22 (a)
zhp-3 35
  • 15 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.285 35
  • 28 (a)
Species where no ortholog for RNF212B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RNF212B Gene

Gene Tree for RNF212B (if available)
Gene Tree for RNF212B (if available)

Paralogs for RNF212B Gene

Paralogs for RNF212B Gene

genes like me logo Genes that share paralogs with RNF212B: view

Variants for RNF212B Gene

Sequence variations from dbSNP and Humsavar for RNF212B Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs10047910 -- 23,220,480(+) tgagc(C/T)gagat intron-variant
rs10130376 -- 23,211,788(+) tgcaa(A/T)cttgg intron-variant
rs10130456 -- 23,211,880(+) accat(A/G)cctgg intron-variant
rs10134378 -- 23,202,800(+) gagcc(A/G)agatt intron-variant
rs10137582 -- 23,223,312(+) tatga(C/G)agacc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RNF212B Gene

Variant ID Type Subtype PubMed ID
esv2658154 CNV deletion 23128226
esv2763062 CNV gain 21179565
esv3633774 CNV loss 21293372
esv3633775 CNV loss 21293372
nsv1112497 CNV deletion 24896259
nsv977447 CNV duplication 23825009

Variation tolerance for RNF212B Gene

Gene Damage Index Score: 1.59; 30.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RNF212B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNF212B Gene

Disorders for RNF212B Gene

Relevant External Links for RNF212B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF212B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF212B Gene

Publications for RNF212B Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 3 4 64
  2. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3 64

Products for RNF212B Gene

Sources for RNF212B Gene

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