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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNF19B Gene

protein-coding   GIFtS: 50
GCID: GC01M033402

Ring Finger Protein 19B

(Previous name: IBR domain containing 3)
(Previous symbol: IBRDC3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ring Finger Protein 19B1 2 3     IBR Domain-Containing Protein 32 3
IBRDC31 2 3 5     E3 Ubiquitin-Protein Ligase RNF19B2
NKLAM2 3 5     EC 6.3.2.-3
IBR Domain Containing 31 2     EC 6.3.28
Natural Killer Lytic-Associated Molecule2 3     

External Ids:    HGNC: 268861   Entrez Gene: 1275442   Ensembl: ENSG000001165147   OMIM: 6108725   UniProtKB: Q6ZMZ03   

Export aliases for RNF19B gene to outside databases

Previous GC identifers: GC01M033175 GC01M031517


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RNF19B Gene:
IBRDC3 is a cytolysis-associated transmembrane protein expressed in natural killer (NK) cells and T lymphocytes
following cytokine stimulation (Kozlowski et al., 1999 (PubMed 10438909)).(supplied by OMIM, Mar 2008)

GeneCards Summary for RNF19B Gene: 
RNF19B (ring finger protein 19B) is a protein-coding gene. Diseases associated with RNF19B include avian influenza, and influenza, and among its related super-pathways are Class I MHC mediated antigen processing & presentation and Immune System. GO annotations related to this gene include zinc ion binding and ligase activity. An important paralog of this gene is RNF14.

UniProtKB/Swiss-Prot: RN19B_HUMAN, Q6ZMZ0
Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and
UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as
UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNF19B gene promoter:
         Nkx3-1   Nkx3-1 v4   AML1a   HNF-4alpha2   Nkx3-1 v1   Nkx2-5   Nkx3-1 v2   COMP1   Chx10   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNF19B promoter sequence
   Search SABiosciences Chromatin IP Primers for RNF19B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF19B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p35.1   Ensembl cytogenetic band:  1p35.1   HGNC cytogenetic band: 1p35.1

RNF19B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF19B gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M033402:  view genomic region     (about GC identifiers)

Start:
33,402,046 bp from pter      End:
33,430,286 bp from pter
Size:
28,241 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RN19B_HUMAN, Q6ZMZ0 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF19B  
Size: 732 amino acids; 77925 Da
Subunit: Interacts with UBE2L3, UBE2L6 and UCKL1
Subcellular location: Cytoplasmic granule membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAI13561.1; Type=Erroneous initiation; Sequence=CAI19336.1; Type=Erroneous initiation;
Sequence=EAX07490.1; Type=Erroneous initiation;
Secondary accessions: Q0VG77 Q5TH44 Q5TH45 Q6P6A4 Q8N2S8 Q8WUF3
Alternative splicing: 4 isoforms:  Q6ZMZ0-1   Q6ZMZ0-2   Q6ZMZ0-3   Q6ZMZ0-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RNF19B: NX_Q6ZMZ0

Explore proteomics data for RNF19B at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZMZ0

  • 4/10 DME Specific Peptides for RNF19B (Q6ZMZ0) (see all 10)
     KYEEFMLRR  DDIKPCPRC  SKHKRNLAI  SLCRGGGCGV 

    RNF19B Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RNF19B Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001120833.1  NP_699172.2  

    ENSEMBL proteins: 
     ENSP00000362555   ENSP00000349482   ENSP00000235150  
    Reactome Protein details: Q6ZMZ0
    Human Recombinant Protein Products for RNF19B: 
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    Cloud-Clone Corp. Proteins for RNF19B 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    RNF19B for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers

    3 InterPro protein domains:
     IPR002867 Znf_C6HC
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q6ZMZ0

    ProtoNet protein and cluster: Q6ZMZ0

    1 Blocks protein domain: IPB002867 Zn-finger

    UniProtKB/Swiss-Prot: RN19B_HUMAN, Q6ZMZ0
    Domain: The first IBR-type zinc finger is the most crucial for interaction with UBE2L3, UBE2L6 and UCKL1
    Similarity: Belongs to the RBR family. RNF19 subfamily
    Similarity: Contains 1 IBR-type zinc finger
    Similarity: Contains 2 RING-type zinc fingers


    RNF19B for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RN19B_HUMAN, Q6ZMZ0
    Function: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and
    UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as
    UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells
    Induction: In natural killer cells, by IFNB1/IFN-beta and IL2/interleukin-2 (at protein level)

         Enzyme Numbers (IUBMB): EC 6.3.2.-1 EC 6.3.22

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16709802
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--
         
    RNF19B for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for RNF19B:
     Increased cell number in G2M,  

         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Rnf19b):
     immune system  tumorigenesis 

    RNF19B for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Rnf19btm1Jkorn for RNF19B

       inGenious Targeting Laboratory - Custom generated mouse model solutions for RNF19B 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for RNF19B About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation0.83
    Class I MHC mediated antigen processing & presentation0.83
    2Immune System
    Immune System0.56
    Adaptive Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for RNF19B
        Antigen processing: Ubiquitination & Proteasome degradation
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    UniProtKB/Swiss-Prot: RN19B_HUMAN, Q6ZMZ0
    Pathway: Protein modification; protein ubiquitination


    RNF19B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF19B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for RNF19B (Q6ZMZ01, 3 ENSP000003625554) via UniProtKB, MINT, STRING, and/or I2D (see all 6)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2L6O149331, 3, ENSP000002871564EBI-2466594,EBI-2129974 I2D: score=2 STRING: ENSP00000287156
    UBE2L3P680361, 3, ENSP000003442594EBI-2466594,EBI-711173 I2D: score=2 STRING: ENSP00000344259
    UCKL1Q9NWZ51, 3, ENSP000003461554EBI-2466594,EBI-2466660 I2D: score=1 STRING: ENSP00000346155
    BTG4Q9NY303, ENSP000003483004I2D: score=1 STRING: ENSP00000348300
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--

    RNF19B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNF19B (RN19B)

    Search CenterWatch for drugs/clinical trials and news about RNF19B / RN19B

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RNF19B gene (2 alternative transcripts): 
    NM_001127361.1  NM_153341.2  

    Unigene Cluster for RNF19B:

    Ring finger protein 19B
    Hs.591504  [show with all ESTs]
    Unigene Representative Sequence: NM_001127361
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373456(uc010oho.2 uc010ohp.2) ENST00000356990(uc001bwm.4)
    ENST00000235150
    miRNA
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    hsa-miR-183* hsa-miR-589* hsa-miR-648 hsa-miR-218 hsa-miR-103a-2*
    SwitchGear 3'UTR luciferase reporter plasmidRNF19B 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK074486.1 AK131439.1 BC020595.2 BC062374.1 BC113560.1 BC143687.1 

    4 DOTS entries:

    DT.87078211  DT.97778219  DT.121416726  DT.97768332 

    24/91 AceView cDNA sequences (see all 91):

    BM846457 BM661996 BC062374 BF849776 BM782150 CD672310 BM720364 BM689928 
    BQ438077 AA459064 AI761150 AA808556 AA369389 BM678705 AI220568 BX111998 
    BQ962407 BF060706 AA417244 AA442330 BC020595 BF093794 BF982125 AA214177 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for RNF19B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9a · 9b · 9c
    SP1:                                                                              
    SP2:                                                              -               
    SP3:                                                        -     -               


    ECgene alternative splicing isoforms for RNF19B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNF19B expression in normal human tissues (normalized intensities)      RNF19B embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGTGTGTCA
    RNF19B Expression
    About this image


    RNF19B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 4 entries
             Granulocytes Peripheral Blood
             monocytes   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Eye (Sensory Organs)
             lens   
     
     Testis (Reproductive System)

    See RNF19B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNF19B

    SOURCE GeneReport for Unigene cluster: Hs.591504

    UniProtKB/Swiss-Prot: RN19B_HUMAN, Q6ZMZ0
    Tissue specificity: Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells.
    Present in natural killer cells (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including RNF19B: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for RNF19B gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnf19b1 , 5 ring finger protein 19B1, 5 91.84(n)1
    95.69(a)1
      4 (62.76 cM)5
    752341  NM_029219.11  NP_083495.11 
     1290584095 
    chicken
    (Gallus gallus)
    Aves RNF19B1 ring finger protein 19B 79.68(n)
    88.35(a)
      419669  XM_417816.3  XP_417816.3 
    lizard
    (Anolis carolinensis)
    Reptilia RNF19B6
    Uncharacterized protein
    75(a)
    1 ↔ 1
    GL343711.1(17266-36784)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.23432 Transcribed sequence with moderate similarity to protein more 80.63(n)    AL896899.2 
    zebrafish
    (Danio rerio)
    Actinopterygii rnf19b1 ring finger protein 19B 64.02(n)
    65.37(a)
      562396  NM_001202440.1  NP_001189369.1 
    worm
    (Caenorhabditis elegans)
    Secernentea Y49F6B.96
    C17H11.66
    Protein C17H11.6, isoform a
    37(a)
    27(a)
    many ↔ many
    many ↔ many
    II(3493921-3499393)
    X(8185194-8203784)


    ENSEMBL Gene Tree for RNF19B (if available)
    TreeFam Gene Tree for RNF19B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RNF19B gene
    RNF142  RNF144A2  RNF144B2  RNF19A2  
    1 SIMAP similar gene for RNF19B using alignment to 4 protein entries:     RN19B_HUMAN (see all proteins):
    RNF19A

    RNF19B for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for RNF19B
    PGOHUM00000239049 PGOHUM00000241439 PGOHUM00000241440 PGOHUM00000233666 PGOHUM00000233667


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/665 SNPs in RNF19B are shown (see all 665)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1465125631,2
    C--33401632(+) GGCGTA/GAGCCA 2 -- int10--------
    rs1410376831,2
    --33401642(+) ACCATA/GCCTGA 2 -- int10--------
    rs609915591,2
    F--33401749(+) GTTTTA/CAGAGT 2 -- int11Minor allele frequency- C:0.03EA 120
    rs1946371,2
    C,F,O,A,H--33401773(-) CCTCTA/GGAAGC 2 -- int119Minor allele frequency- G:0.20MN NS EA NA 2410
    rs1486690111,2
    C--33401790(+) AAGTT-/AAGTTT 2 -- int10--------
    rs1447942261,2
    --33401920(+) TACTGC/TGGTTG 2 -- int10--------
    rs80401,2
    C,F,A,H--33402172(+) TTAACC/TAATAA 2 -- ut31 ese324Minor allele frequency- T:0.19MN NA EA NS 4328
    rs1858783711,2
    --33402219(+) CTAACA/GGCAAA 2 -- ut310--------
    rs1903534801,2
    --33402255(+) ATTGTG/TAATTT 2 -- ut310--------
    rs1178077101,2
    F--33402323(+) AAATCT/CCTACC 2 -- ut311Minor allele frequency- C:0.02EA 120

    HapMap Linkage Disequilibrium report for RNF19B (33402046 - 33430286 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for RNF19B:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2664245CNV Deletion23128226
    nsv509169CNV Insertion20534489
    nsv834602CNV Loss17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610872    OMIM disorders: --

    2 diseases for RNF19B:    About MalaCards
    avian influenza    influenza


    RNF19B for disorders           About GeneDecksing


    Export disorders for RNF19B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNF19B gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with RNF19B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. NK lytic-associated molecule, involved in NK cytotoxic function, is an E3 ligase. (PubMed id 16709802)1, 2 Fortier J.M. and Kornbluth J. (2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    5. NK lytic-associated molecule: a novel gene selectively expressed in cells with cytolytic function. (PubMed id 10438909)1, 2 Kozlowski M.... Kornbluth J. (1999)
    6. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Identification of the human testis protein phosphatase 1 interactome. (PubMed id 21382349)1 Fardilha M....Silva E.F. (2011)
    10. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 127544 HGNC: 26886 AceView: IBRDC3 Ensembl:ENSG00000116514 euGenes: HUgn127544
    ECgene: RNF19B H-InvDB: RNF19B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNF19B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RNF19B gene:
    Search GeneIP for patents involving RNF19B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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