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Aliases for RNF183 Gene

Aliases for RNF183 Gene

  • Ring Finger Protein 183 2 3

External Ids for RNF183 Gene

Previous GeneCards Identifiers for RNF183 Gene

  • GC09M113139
  • GC09M115099
  • GC09M116059
  • GC09M085666

Summaries for RNF183 Gene

GeneCards Summary for RNF183 Gene

RNF183 (Ring Finger Protein 183) is a Protein Coding gene. An important paralog of this gene is RNF223.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF183 Gene

Genomics for RNF183 Gene

Regulatory Elements for RNF183 Gene

Genomic Location for RNF183 Gene

113,297,093 bp from pter
113,303,376 bp from pter
6,284 bases
Minus strand

Genomic View for RNF183 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNF183 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF183 Gene

Proteins for RNF183 Gene

  • Protein details for RNF183 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 183
    Protein Accession:
    Secondary Accessions:

    Protein attributes for RNF183 Gene

    192 amino acids
    Molecular mass:
    21617 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF183 Gene

Proteomics data for RNF183 Gene at MOPED

Post-translational modifications for RNF183 Gene

No Post-translational modifications

Other Protein References for RNF183 Gene

No data available for DME Specific Peptides for RNF183 Gene

Domains for RNF183 Gene

Gene Families for RNF183 Gene

Protein Domains for RNF183 Gene

Suggested Antigen Peptide Sequences for RNF183 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 RING-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF183: view

Function for RNF183 Gene

Gene Ontology (GO) - Molecular Function for RNF183 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with RNF183: view

Phenotypes for RNF183 Gene

GenomeRNAi human phenotypes for RNF183:
genes like me logo Genes that share phenotypes with RNF183: view

Animal Model Products

miRNA for RNF183 Gene

miRTarBase miRNAs that target RNF183

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF183 Gene

Localization for RNF183 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF183 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for RNF183 Gene COMPARTMENTS Subcellular localization image for RNF183 gene
Compartment Confidence
nucleus 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for RNF183 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNF183: view

Pathways for RNF183 Gene

SuperPathways for RNF183 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF183 Gene


No data available for Pathways by source for RNF183 Gene

Transcripts for RNF183 Gene

Unigene Clusters for RNF183 Gene

Ring finger protein 183:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNF183 Gene

No ASD Table

Relevant External Links for RNF183 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF183 Gene

mRNA expression in normal human tissues for RNF183 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RNF183 Gene

This gene is overexpressed in Kidney - Cortex (8.6), Minor Salivary Gland (7.6), Testis (5.8), and Esophagus - Mucosa (5.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for RNF183 Gene

SOURCE GeneReport for Unigene cluster for RNF183 Gene Hs.729641

genes like me logo Genes that share expressions with RNF183: view

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for RNF183 Gene

Orthologs for RNF183 Gene

This gene was present in the common ancestor of mammals.

Orthologs for RNF183 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RNF183 35
  • 85.64 (n)
  • 81.91 (a)
RNF183 36
  • 82 (a)
(Canis familiaris)
Mammalia RNF183 35
  • 89.12 (n)
  • 89.42 (a)
(Mus musculus)
Mammalia Rnf183 35
  • 85.79 (n)
  • 88.42 (a)
Rnf183 16
Rnf183 36
  • 88 (a)
(Pan troglodytes)
Mammalia RNF183 35
  • 98.96 (n)
  • 97.92 (a)
RNF183 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Rnf183 35
  • 84.39 (n)
  • 86.84 (a)
(Monodelphis domestica)
Mammalia RNF183 36
  • 75 (a)
Species with no ortholog for RNF183:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for RNF183 Gene

Gene Tree for RNF183 (if available)
Gene Tree for RNF183 (if available)

Paralogs for RNF183 Gene

Paralogs for RNF183 Gene

genes like me logo Genes that share paralogs with RNF183: view

Variants for RNF183 Gene

Sequence variations from dbSNP and Humsavar for RNF183 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs1061943 -- 113,297,402(-) GAGCG(A/G)CCTCC utr-variant-3-prime
rs2296073 -- 113,299,348(+) AGATG(C/T)GAAGA upstream-variant-2KB, intron-variant
rs3750532 -- 113,298,207(-) CGCGA(A/G)GCCTC utr-variant-5-prime
rs3750533 - 113,297,941(-) TGCTC(A/G)CCCTG missense, reference
rs3750534 - 113,297,844(-) GCCTC(A/G)AGTCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RNF183 Gene

Variant ID Type Subtype PubMed ID
nsv893744 CNV Gain 21882294

Relevant External Links for RNF183 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNF183 Gene

Disorders for RNF183 Gene

No disorders were found for RNF183 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for RNF183 Gene

Publications for RNF183 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for RNF183 Gene

Sources for RNF183 Gene

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