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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNF167 Gene

protein-coding   GIFtS: 48
GCID: GC17P004845

ring finger protein 167

 Explore 2 diseases affiliated with
RNF167 via our new
 Human Malady Compendium 
Biological research products
for RNF167
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ring Finger Protein 1671 2 3
RING1052 3
DKFZP566H0731
5730408C10Rik2
E3 Ubiquitin-Protein Ligase RNF1672
EC 6.3.2.-3

External Ids:    HGNC: 245441   Entrez Gene: 260012   Ensembl: ENSG000001085237   OMIM: 6104315   UniProtKB: Q9H6Y73   

Export aliases for RNF167 gene to outside databases

Previous GC identifer: GC17P004784


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RNF167:
RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM
602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 (PubMed 16314844)).(supplied by OMIM, Mar
2008)

UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7
Function: May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from
specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May
play a role in growth regulation involved in G1/S transition




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNF167 gene promoter:
         E2F-3a   E2F-5   E2F-1   E2F   AP-1   E2F-2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNF167 promoter sequence
   Search SABiosciences Chromatin IP Primers for RNF167

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF167


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.2   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.3

RNF167 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF167 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P004845:  view genomic region     (about GC identifiers)

Start:
4,843,303 bp from pter      End:
4,848,517 bp from pter
Size:
5,215 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF167 precursor  
Size: 350 amino acids; 38299 Da
Subunit: Interacts with SLC22A18
Subcellular location: Endomembrane system; Single-pass membrane protein. Note=Targeted to cytoplasmic membranes
Sequence caution: Sequence=AAP34453.1; Type=Frameshift; Positions=65;
Secondary accessions: D3DTK8 Q6XYE0 Q8NDC1 Q9Y3V1

Explore the universe of human proteins at neXtProt for RNF167: NX_Q9H6Y7

Post-translational modifications:

  • Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E11
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H6Y7

  • RNF167 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_056343.1  
    ENSEMBL proteins: 
     ENSP00000459324   ENSP00000459581   ENSP00000458375   ENSP00000458794   ENSP00000262482  
     ENSP00000458905   ENSP00000460190   ENSP00000458189   ENSP00000460991   ENSP00000460024  
     ENSP00000466753  

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    Uscn Proteins for RNF167

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA16314844
    GO:0012505endomembrane system IEA--
    GO:0016021integral to membrane IEA--


    RNF167 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    RNF167 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001841 Znf_RING
     IPR003137 Protease-assoc_domain
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9H6Y7

    ProtoNet protein and cluster: Q9H6Y7

    1 Blocks protein family: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7
    Similarity: Contains 1 PA (protease associated) domain
    Similarity: Contains 1 RING-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7
    Function: May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from
    specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May
    play a role in growth regulation involved in G1/S transition

    Enzyme Number (IUBMB): EC 6.3.2.-1

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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity IDA16314844
    GO:0005515protein binding IPI16314844
    GO:0008270zinc ion binding IEA--


    RNF167 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF167

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/15 Interacting proteins for RNF167 (Q9H6Y73 ENSP000002624824) via UniProtKB, MINT, STRING, and/or I2D (see all 15)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2D2P628373, ENSP000003817174I2D: score=2 STRING: ENSP00000381717
    UBE2D3P610773, ENSP000003497224I2D: score=2 STRING: ENSP00000349722
    UBE2NP610883, ENSP000003161764I2D: score=2 STRING: ENSP00000316176
    UBE2WQ96B023, ENSP000003974534I2D: score=2 STRING: ENSP00000397453
    UBE2MP610813, ENSP000002530234I2D: score=1 STRING: ENSP00000253023
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000209protein polyubiquitination IDA16314844
    GO:0045786negative regulation of cell cycle IMP16314844


    RNF167 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNF167
    Search CenterWatch for drugs/clinical trials and news about RNF167 / RN167 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for RNF167 gene: 
    NM_015528.1  

    Unigene Cluster for RNF167:

    Ring finger protein 167
    Hs.7158  [show with all ESTs]
    Unigene Representative Sequence: AK025329
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000571816 ENST00000571365 ENST00000573404 ENST00000576452 ENST00000572430
    ENST00000262482(uc002fzs.3 uc002fzu.3) ENST00000570328 ENST00000575111(uc002fzw.2)
    ENST00000576229 ENST00000570492 ENST00000575400 ENST00000572554 ENST00000572382(uc002fzy.3)
    ENST00000576965 ENST00000575524 ENST00000574548

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    Additional cDNA sequence: 

    AK025329.1 AL050060.1 AL079315.1 AL834284.1 AY203930.1 AY960626.1 BC010139.2 BC013222.1 
    CR457340.1 

    24/29 DOTS entries (see all 29):

    DT.91759128  DT.100852983  DT.100830162  DT.75173986  DT.100852993  DT.100799467  DT.91759131  DT.100887252 
    DT.95268378  DT.120890914  DT.95268381  DT.40107131  DT.100852982  DT.97860395  DT.100852991  DT.100852998 
    DT.95242193  DT.100830072  DT.120891263  DT.95268384  DT.100852988  DT.95268385  DT.95268395  DT.100852990 

    24/570 AceView cDNA sequences (see all 570):

    BU630489 CR592240 BM848135 BQ070469 AL577594 BQ772870 BU733990 BQ437771 
    AI523551 Z46220 BX404244 CF128587 CB129777 CD722949 BQ426037 CR601513 
    CB150054 AI289324 BQ940689 BQ009183 BM773166 Z45387 BQ686986 CB053698 

    GeneLoc Exon Structure

    5/20 Alternative Splicing Database (ASD) splice patterns (SP) for RNF167 (see all 20)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^
    SP1:                                      -     -     -     -     -     -     -     -                                                     -                     
    SP2:                                                                                                                                      -                     
    SP3:                                                                                                                                      -                     
    SP4:                                                                                                                                      -                     
    SP5:                                      -     -     -                       -                                                           -                     

    ExUns: 12a · 12b · 12c ^ 13a · 13b · 13c
    SP1:                                    
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for RNF167

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNF167 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCTACCACAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    RNF167 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LimbLimb BudLimb Bud Mesenchyme CellsMesoderm
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See RNF167 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNF167

    SOURCE GeneReport for Unigene cluster: Hs.7158

    UniProtKB/Swiss-Prot: RN167_HUMAN, Q9H6Y7
    Tissue specificity: Strongly expressed in the kidney and liver (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Arrays including RNF167: 
              Ubiquitination (Ubiquitylation) Pathway in human mouse rat
              Ubiquitin Ligases in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RNF167 gene from 5/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003338271 e3 ubiquitin-protein ligase RNF167-like 58.85(n)
    55.86(a)
      100333827  XM_002662216.2  XP_002662262.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG102776
    --
    19(a)
    1 → many
    3R(2208633-2214026)
    worm
    (Caenorhabditis elegans)
    Secernentea C18B12.46
    Protein C18B12.4
    19(a)
    possible ortholog
    X(15036627-15040532)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G095601 protease-associated (PA) RING/U-box zinc finger-containing more 42.96(n)
    35.56(a)
      826540  NM_117024.3  NP_192694.2 
    rice
    (Oryza sativa)
    Liliopsida --
    --
    RING finger protein 13, putative, expressed
    16(a)
    16(a)
    many ↔ many
    many ↔ many
    3(3645869-3650576)
    8(227213-231453)


    ENSEMBL Gene Tree for RNF167 (if available)
    TreeFam Gene Tree for RNF167 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RNF167 gene
    ZNRF32  RNF432  RNF1482  RNF1492  RNF1332  RNF1302  RNF1502  RNF1282  
    RNF2152  ZNRF42  RNF132  
    6 SIMAP similar genes for RNF167 using alignment to 8 protein entries:     RN167_HUMAN (see all proteins):
    RNF13    RNF122    ZNRF4    RNF181    RNF24    TRIM3

    RNF167 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/85 NCBI SNPs in RNF167 are shown (see all 85    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1470534241,2
    C,--4845707(+) GTCAAC/TGGGTC 2 N syn10--------
    rs1475942121,2
    C,F,--4845725(+) ATTGCG/ACTGCT 2 /A syn11Minor allele frequency- A:0.00NA 4550
    rs2008210571,2
    C,--4845756(+) TTGACC/TTCAAG 2 L F mis10--------
    rs2382471,2
    C,F,O,A,H,--4845768(+) TTGCTG/AAATGA 1 -- int130Minor allele frequency- A:0.40MN NS EA NA WA CSA EU 4176
    rs1996559851,2
    --4845869(+) CTCCCC/TAGGTC 1 -- int10--------
    rs2020461401,2
    --4845889(+) CAGAAG/TGCTGG 2 K N mis10--------
    rs1490500301,2
    F--4845904(+) GGTGCC/TGCTGT 2 A syn11Minor allele frequency- T:0.00NA 4552
    rs118712321,2
    C,F,H,--4846045(+) AGCCAA/GTCCTT 1 -- int112Minor allele frequency- G:0.03NS EA NA 1074
    rs1382358201,2
    C,--4846109(+) AGAAG-/GTTGTGAG 1 -- int10--------
    rs2011606091,2
    --4846138(+) TTGATC/TCCTGC 1 -- int10--------

    HapMap Linkage Disequilibrium report for RNF167 (4843303 - 4848517 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for RNF167
         2 CNVs: 4987 4986

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    RNF167 for disorders           About GeneDecksing

    OMIM gene information: 610431    OMIM disorders: --

    2 diseases for RNF167:    About MalaCards
    multiple myeloma    myeloma


    Export disorders for RNF167 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNF167 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with RNF167)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Goliath family E3 ligases regulate the recycling endos ome pathway via VAMP3 ubiquitylation. (PubMed id 23353890)1, 3 Yamazaki Y....Palmer R.H. (2013)
    2. Ubiquitin ligase RNF167 regulates AMPA receptor-mediat ed synaptic transmission. (PubMed id 23129617)1, 3 Lussier M.P....Roche K.W. (2012)
    3. Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105. (PubMed id 16314844)1, 2 Yamada H.Y. and Gorbsky G.J. (2006)
    4. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26001 HGNC: 24544 AceView: RNF167 Ensembl:ENSG00000108523 euGenes: HUgn26001
    ECgene: RNF167 H-InvDB: RNF167

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNF167 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RNF167 gene:
    Search GeneIP for patents involving RNF167

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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