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RNF166 Gene

protein-coding   GIFtS: 48
GCID: GC16M088762

Ring Finger Protein 166

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ring Finger Protein 1661 2

External Ids:    HGNC: 288561   Entrez Gene: 1159922   Ensembl: ENSG000001587177   UniProtKB: Q96A373   

Export aliases for RNF166 gene to outside databases

Previous GC identifers: GC16M088508 GC16M087290 GC16M074457


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for RNF166 Gene:
RNF166 (ring finger protein 166) is a protein-coding gene. An important paralog of this gene is RNF125.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RNF166 gene promoter:
         GR   Pax-5   Olf-1   Tal-1beta   E47   CREB   deltaCREB   GR-alpha   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNF166 promoter sequence
   Search Chromatin IP Primers for RNF166

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RNF166


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3   Ensembl cytogenetic band:  16q24.3   HGNC cytogenetic band: 16q24.3

RNF166 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF166 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M088762:  view genomic region     (about GC identifiers)

Start:
88,762,903 bp from pter      End:
88,772,829 bp from pter
Size:
9,927 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: RN166_HUMAN, Q96A37 (See protein sequence)
Recommended Name: RING finger protein 166  
Size: 237 amino acids; 26122 Da
Secondary accessions: B3KQ03 D3DX75 H3BTU8 Q96DM0
Alternative splicing: 3 isoforms:  Q96A37-1   Q96A37-2   Q96A37-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RNF166: NX_Q96A37

Explore proteomics data for RNF166 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys129, Lys167
  • Modification sites at PhosphoSitePlus

  • See RNF166 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001165286.1  NP_001165287.1  NP_849163.1  

    ENSEMBL proteins: 
     ENSP00000326095   ENSP00000455617   ENSP00000455539   ENSP00000446301   ENSP00000440454  
     ENSP00000457374   ENSP00000457336  

    RNF166 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for RNF166

     
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    antibodies-online proteins for RNF166 (4 products) 

     
    antibodies-online peptides for RNF166

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    antibodies-online antibodies for RNF166 (11 products) 

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    Cloud-Clone Corp. ELISAs for RNF166
    Cloud-Clone Corp. CLIAs for RNF166
    Search eBioscience for ELISAs for RNF166 
    antibodies-online kits for RNF166 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RNF: RING-type (C3HC4) zinc fingers

    5 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR008598 Di19_Zn_binding
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q96A37

    ProtoNet protein and cluster: Q96A37

    2 Blocks protein domains:
    IPB001841 Zn-finger
    IPB003903 Ubiquitin interacting motif


    UniProtKB/Swiss-Prot: RN166_HUMAN, Q96A37
    Similarity: Contains 1 RING-type zinc finger
    Similarity: Contains 1 UIM (ubiquitin-interacting motif) repeat


    Find genes that share domains with RNF166           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with RNF166           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for RNF166:
     Increased cell death HMECs cel  Synthetic lethal with Ras 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for RNF166

    miRNA
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    Block miRNA regulation of human, mouse, rat RNF166 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNF166 (see all 17):
    hsa-miR-25 hsa-miR-575 hsa-miR-624* hsa-miR-3190 hsa-miR-511 hsa-miR-548c-3p hsa-miR-92b hsa-miR-384
    SwitchGear 3'UTR luciferase reporter plasmidRNF166 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for RNF166
    Predesigned siRNA for gene silencing in human, mouse, rat RNF166

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): RNF166 (NM_178841)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF166

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including RNF166: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for RNF166

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for RNF166 (Q96A373 ENSP000003260954) via UniProtKB, MINT, STRING, and/or I2D (see all 18)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2D2P628373, ENSP000003817174I2D: score=2 STRING: ENSP00000381717
    UBE2D3P610773, ENSP000003497224I2D: score=2 STRING: ENSP00000349722
    UBE2UQ5VVX93, ENSP000003601164I2D: score=2 STRING: ENSP00000360116
    UBE2WQ96B023, ENSP000003974534I2D: score=2 STRING: ENSP00000397453
    UBE2D1P516683, ENSP000003630194I2D: score=2 STRING: ENSP00000363019
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RNF166 (RN166)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for RNF166 gene (3 alternative transcripts): 
    NM_001171815.1  NM_001171816.1  NM_178841.3  

    Unigene Cluster for RNF166:

    Ring finger protein 166
    Hs.513804  [show with all ESTs]
    Unigene Representative Sequence: NM_001171816
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000312838(uc021tmo.1 uc002flk.3) ENST00000567408 ENST00000562544
    ENST00000537718 ENST00000541206(uc021tmn.1) ENST00000565083 ENST00000568683
    ENST00000567844 ENST00000564894 ENST00000562499 ENST00000569478
    miRNA
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    Block miRNA regulation of human, mouse, rat RNF166 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNF166 (see all 17):
    hsa-miR-25 hsa-miR-575 hsa-miR-624* hsa-miR-3190 hsa-miR-511 hsa-miR-548c-3p hsa-miR-92b hsa-miR-384
    SwitchGear 3'UTR luciferase reporter plasmidRNF166 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat RNF166
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF166
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for RNF166
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RNF166
      QuantiTect SYBR Green Assays in human, mouse, rat RNF166
      QuantiFast Probe-based Assays in human, mouse, rat RNF166

    Additional mRNA sequence: 

    AK026860.1 AK057106.1 AK057201.1 AK290920.1 BC013948.2 BC017226.1 

    13 DOTS entries:

    DT.107949  DT.95070030  DT.100782577  DT.91947399  DT.100654430  DT.91850458  DT.100782581  DT.91936004 
    DT.100665280  DT.100782578  DT.100782582  DT.75157380  DT.95070037 

    Selected AceView cDNA sequences (see all 108):

    BX280868 CR612154 BE312288 CR596749 CR598819 CR620092 BI489894 BG830046 
    AK057201 CB216673 AK026860 BQ440544 BI819883 BU856178 BQ920690 AI570133 
    BI825608 AL520109 AI282666 AA422021 BF512191 BX452328 BM805412 BI160750 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for RNF166 (see all 8)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c · 9d
    SP1:        -     -     -     -     -                       -     -                             -                           
    SP2:        -     -     -     -     -                       -     -                             -                           
    SP3:                                -                       -     -                             -                           
    SP4:                                                              -                             -                           
    SP5:                                                                                                                        


    ECgene alternative splicing isoforms for RNF166

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    RNF166 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGTCTGCTG
    RNF166 Expression
    About this image


    RNF166 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)
             Bone Marrow
    RNF166 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RNF166 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.513804
        Pathway & Disease-focused RT2 Profiler PCR Array including RNF166: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF166

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for RNF166 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnf1661 , 5 ring finger protein 1661, 5 91.14(n)1
    98.73(a)1
      8 (71.17 cM)5
    687181  NM_001033142.21  NP_001028314.11 
     1224661475 
    chicken
    (Gallus gallus)
    Aves RNF1661 ring finger protein 166 83.69(n)
    86.7(a)
      425360  NM_001012935.1  NP_001012953.1 
    lizard
    (Anolis carolinensis)
    Reptilia RNF1666
    ring finger protein 166
    75(a)
    1 ↔ 1
    GL343670.1(150179-158943)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia rnf1661 ring finger protein 166 77.12(n)
    89.41(a)
      779674  NM_001078759.1  NP_001072227.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003345241 RING finger protein 166-like 75.81(n)
    83.12(a)
      100334524  XM_002662942.2  XP_002662988.2 


    ENSEMBL Gene Tree for RNF166 (if available)
    TreeFam Gene Tree for RNF166 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for RNF166 gene
    RNF1252  RNF1382  RNF1142  
    7 SIMAP similar genes for RNF166 using alignment to 4 protein entries:     RN166_HUMAN (see all proteins):
    ZNF313    RNF114    TRIM17    TRIM5    TRIM39    RNF4
    TRIM60

    Find genes that share paralogs with RNF166           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for RNF166 (see all 296)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1388708581,2
    --88762416(+) CTGGAA/GAACAG 3 -- int10--------
    rs751421001,2
    C,F--88762449(+) GGCCCC/GTCAGA 3 -- int11Minor allele frequency- G:0.04EA 120
    rs732605971,2
    C,F--88762457(+) AGAGAA/GCTACA 3 -- int12Minor allele frequency- G:0.18WA 120
    rs1151036651,2
    C,F--88762473(+) TTAGTG/CTAACA 3 -- int12Minor allele frequency- C:0.02WA EA 238
    rs1143231611,2
    C,F--88762504(+) ATCCAG/AGAGGT 3 -- int11Minor allele frequency- A:0.03WA 118
    rs118635971,2
    C,F,H--88762506(+) CCAGGA/CGGTGC 3 -- int19Minor allele frequency- C:0.26NA WA CSA 252
    rs1413100651,2
    --88762544(+) TGACAC/TGGGAG 3 -- int10--------
    rs1502245991,2
    --88762545(+) GACACA/GGGAGG 3 -- int10--------
    rs356394681,2
    C--88762933(+) TAAACT/-TTTTT 3 -- ut311Minor allele frequency- -:0.00NA 2
    rs11325791,2
    C,F,A,H--88762943(-) TTTTTT/AAAAAA 3 -- ut31 trp34Minor allele frequency- A:0.50NA WA 10

    HapMap Linkage Disequilibrium report for RNF166 (88762903 - 88772829 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for RNF166 (see all 21):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833327CNV Loss17160897
    nsv907278CNV Loss21882294
    nsv907268CNV Loss21882294
    nsv907226CNV Loss21882294
    nsv833325CNV Loss17160897
    dgv2981n71CNV Loss21882294
    nsv907296CNV Loss21882294
    nsv907283CNV Loss21882294
    nsv471113CNV Loss18288195
    nsv907305CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RNF166
    DNA2.0 Custom Variant and Variant Library Synthesis for RNF166

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for RNF166 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with RNF166)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    4. Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (amp 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15. (PubMed id 23105109)1 Hayes S.D....UrbAc S. (J. Biol. Chem. 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (Genome Res. 2009)
    10. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)1 van Wijk S.J....Timmers H.T. (Mol. Syst. Biol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 115992 HGNC: 28856 AceView: RNF166 Ensembl:ENSG00000158717 euGenes: HUgn115992
    ECgene: RNF166 H-InvDB: RNF166

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for RNF166 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for RNF166 gene:
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    GeneCards and IP:
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