Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RNF165 Gene

protein-coding GIFtS: 44
GCID: GC18P043914

ring finger protein 165

Explore 1 disease affiliated with
RNF165 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ring Finger Protein 165¹ ²
ARKL2¹ ²

External Ids:	HGNC: 31696¹	Entrez Gene: 494470²	Ensembl: ENSG00000141622⁷	UniProtKB: Q6ZSG1³

Export aliases for RNF165 gene to outside databases

Previous GC identifers: GC18U900221 GC18P042169 GC18P040771

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RNF165:

Encoded in regions involved in pericentric inversions in patients with bipolar affective disorder. (provided by RefSeq,

Jul 2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_010966.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RNF165 gene promoter:
Sox5 NF-1 NCX/Ncx HTF NF-AT GATA-2 SRY NF-AT3 Chx10 NF-AT1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RNF165 promoter sequence

Search SABiosciences Chromatin IP Primers for RNF165

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF165

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.1 Ensembl cytogenetic band: 18q21.1 HGNC cytogenetic band: 18q21.1

RNF165 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF165 gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18P043914: view genomic region (about GC identifiers)

Start:	43,906,772 bp from pter	End:	44,043,103 bp from pter
Size:	136,332 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RN165_HUMAN, Q6ZSG1 (See protein sequence)

Recommended Name: RING finger protein 165

Size: 346 amino acids; 39526 Da

Secondary accessions: B3KVD1

Alternative splicing: 2 isoforms: Q6ZSG1-1 Q6ZSG1-2

Explore the universe of human proteins at neXtProt for RNF165: NX_Q6ZSG1

RNF165 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001243687.1 NP_689683.2

ENSEMBL proteins:

ENSP00000467730 ENSP00000466208 ENSP00000466809 ENSP00000467609 ENSP00000464873

ENSP00000468365 ENSP00000269439 ENSP00000444285

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: RNF165 OriGene Custom Protein Services for RNF165
	GenScript Custom Purified and Recombinant Proteins Services for RNF165
	Novus Biologicals RNF165 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RNF165

RNF165 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for RNF165
	GenScript Custom Superior Antibodies Services for RNF165
	Novus Biologicals RNF165 Antibodies
	Search for Antibodies for RNF165 at Abcam
	Uscn Antibodies for RNF165
	Search ThermoFisher Antibodies for RNF165

Assay Products for RNF165:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RNF165
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RNF165

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RNF165 for domains About GeneDecksing

2 InterPro domains/families:

IPR001841 Znf_RING

IPR013083 Znf_RING/FYVE/PHD

Graphical View of Domain Structure for InterPro Entry Q6ZSG1

ProtoNet protein and cluster: Q6ZSG1

1 Blocks protein family: IPB001841 Zn-finger

UniProtKB/Swiss-Prot: RN165_HUMAN, Q6ZSG1

Similarity: Contains 1 RING-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF165
		8/172 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF165 (see all 172):
		hsa-miR-1321 hsa-miR-631 hsa-miR-1914* hsa-miR-3921 hsa-miR-3162-5p hsa-miR-877* hsa-miR-298 hsa-miR-3649

		SwitchGear 3'UTR luciferase reporter plasmids (see all 2): RNF165 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF165 OriGene shRNA RFP: RNF165 OriGene siRNA: RNF165
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF165

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for RNF165

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RNF165 (NM_152470)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF165
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RNF165

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RNF165
		Search LifeMap BioReagents cell lines for RNF165

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF165

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008270	zinc ion binding	IEA	--

RNF165 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for RNF165:

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RNF165

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/9 Interacting proteins for RNF165 (Q6ZSG1³ ENSP00000269439⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBE2D2	P62837³, ENSP00000381717⁴	I2D: score=2 STRING: ENSP00000381717
UBE2D3	P61077³, ENSP00000349722⁴	I2D: score=2 STRING: ENSP00000349722
UBE2N	P61088³, ENSP00000316176⁴	I2D: score=2 STRING: ENSP00000316176
UBE2W	Q96B02³, ENSP00000397453⁴	I2D: score=2 STRING: ENSP00000397453
UBE2D1	P51668³, ENSP00000363019⁴	I2D: score=2 STRING: ENSP00000363019

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RNF165
Search CenterWatch for drugs/clinical trials and news about RNF165 / RN165

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RNF165 gene (2 alternative transcripts):

NM_001256758.1 NM_152470.2

Unigene Cluster for RNF165:

Ring finger protein 165

Hs.501114 [show with all ESTs]

Unigene Representative Sequence: NM_152470

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000593230 ENST00000587853 ENST00000590330 ENST00000588679 ENST00000592129

ENST00000586604 ENST00000269439(uc002lby.1 uc002lcb.1 uc010dnn.1)

ENST00000592777 ENST00000543885(uc002lca.1)

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF165
		8/172 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF165 (see all 172):
		hsa-miR-1321 hsa-miR-631 hsa-miR-1914* hsa-miR-3921 hsa-miR-3162-5p hsa-miR-877* hsa-miR-298 hsa-miR-3649

		SwitchGear 3'UTR luciferase reporter plasmids (see all 2): RNF165 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF165 OriGene shRNA RFP: RNF165 OriGene siRNA: RNF165
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF165

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RNF165 (NM_152470)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF165
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RNF165

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF165 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RNF165
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF165
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF165

Additional cDNA sequence:

AK055997.1 AK074561.1 AK096648.1 AK122819.1 AK123883.1 AK127467.1 BC012190.1 NR_046357.1

5 DOTS entries:

DT.97803328 DT.80102033 DT.91724792 DT.100017417 DT.100017416

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RNF165 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACGACATTGT

About this image

RNF165 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Blood Brain Barrier

Endothelial Cells

Blood Brain Barrier, Endothelium

Brain

Blood Brain Barrier

Postnatal Endothelial Cells

Blood Brain Barrier, Endothelium

Limb

Zeugopod

Mesenchymal Condensate Cells

Bone, Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 4 LifeMap Cells

Name

Category

PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor EN27 (Embryonic Progenitor Cell)

PureStem™ progenitor Z1 (Embryonic Progenitor Cell)

Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)

See RNF165 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF165

SOURCE GeneReport for Unigene cluster: Hs.501114

SABiosciences Custom PCR Arrays for RNF165

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF165 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat RNF165
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF165
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF165

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF165

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RNF165 gene from 7/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RNF165¹	ring finger protein 165	82.46(n) 88.66(a)		416382 XM_414696.3 XP_414696.3
lizard (Anolis carolinensis)	Reptilia	RNF165⁶	--	86(a)	1 ↔ 1	1(34827093-34857748)
zebrafish (Danio rerio)	Actinopterygii	rnf165b¹	ring finger protein 165b	69.79(n) 72.73(a)		572413 XM_696125.4 XP_701217.3
fruit fly (Drosophila melanogaster)	Insecta	CG6923⁶	--	6(a)	1 → many	3R(7570205-7575751)
worm (Caenorhabditis elegans)	Secernentea	toe-4⁶	Protein TOE-4	11(a)	1 → many	I(12738077-12741139)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G37580⁶	RING-H2 finger protein ATL33	16(a)	1 → many	2(15764728-15765553)
rice (Oryza sativa)	Liliopsida	-- -- (see all 4)	zinc finger, C3HC4 type domain containing protein (see all 4)	27(a) 25(a) (see all 4)	many ↔ many many ↔ many (see all 4)	11(28260929-28261441) 11(28262054-28262566)

ENSEMBL Gene Tree for RNF165 (if available)
TreeFam Gene Tree for RNF165 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RNF165 gene

RNF6² RNF11² RNF38² RLIM² RNF44² RNF111²

1 SIMAP similar gene for RNF165 using alignment to 5 protein entries: RN165_HUMAN (see all proteins):

RNF111

RNF165 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11661320^1,2	H	--	40803891(+)	`gctcaA/Caaaaa`	1	--	int¹ trp³		0	--	--	--	--
rs75188192^1,2		--	43912233(+)	`TGGCCA/GTCTTC`	3	--	us2k¹		0	--	--	--	--
rs140290495^1,2		--	43912258(+)	`TGGGGG/TCAGCC`	3	--	us2k¹		0	--	--	--	--
rs192438846^1,2		--	43912286(+)	`AGAGAA/GCTCAG`	3	--	us2k¹		0	--	--	--	--
rs145199111^1,2		--	43912343(+)	`GGTTCA/TGCCCT`	3	--	us2k¹		0	--	--	--	--
rs137890331^1,2		--	43912349(+)	`GCCCTA/TGCCAC`	3	--	us2k¹		0	--	--	--	--
rs182006813^1,2		--	43912375(+)	`TGTCTA/GGGTAA`	3	--	us2k¹		0	--	--	--	--
rs140700959^1,2		--	43912525(+)	`GCTGGA/GTGCCC`	3	--	us2k¹		0	--	--	--	--
rs9952113^1,2	C,F,	--	43912764(+)	`CCAGCT/CCCACA`	3	--	us2k¹		11		NA WA EA	508
rs117286345^1,2		--	43912859(+)	`AATGTC/TCTCTG`	3	--	us2k¹		1		NA	120

HapMap Linkage Disequilibrium report for RNF165 (43906772 - 44043103 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for RNF165
2 CNVs: 73138 88824
1 Indel: 73137

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF165

DNA2.0 Custom Variant and Variant Library Synthesis for RNF165

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RNF165 for disorders About GeneDecksing

1 disease for RNF165: About MalaCards

bipolar affective disorder

Human Genome Epidemiology (HuGE) Navigator: RNF165 (1 document)

Export disorders for RNF165 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RNF165 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RNF165)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)¹ van Wijk S.J....Timmers H.T. (2009)
Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. (PubMed id 19159218)² Chen R.... Zou H. (2009)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
DNA sequence and analysis of human chromosome 18. (PubMed id 16177791)² Nusbaum C.... Lander E.S. (2005)
Candidate psychiatric illness genes identified in patients with pericentric inversions of chromosome 18. (PubMed id 15722956)¹ Pickard B.S.... Muir W.J. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)¹ Bonaldo M.F.... Soares M.B. (1996)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 494470	HGNC: 31696	Ensembl:ENSG00000141622	euGenes: HUgn494470	ECgene: RNF165
H-InvDB: RNF165

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RNF165	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RNF165 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RNF165 gene:
Search GeneIP for patents involving RNF165

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for RNF165
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF165		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF165
	OriGene Protein Over-expression Lysate for RNF165		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for RNF165		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF165
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RNF165		OriGene Custom Protein Services for RNF165
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNF165
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF165
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF165
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF165
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF165
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF165

	GenScript Custom Purified and Recombinant Proteins Services for RNF165		GenScript cDNA clones with any tag delivered in your preferred vector for RNF165
	GenScript Custom Assay Services for RNF165		GenScript Custom Superior Antibodies Services for RNF165
	GenScript Custom overexpressing Cell Line Services for RNF165		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RNF165 promoter
	Search Chromatin IP Primers for RNF165
	RT² qPCR Primer Assay in human, mouse, rat RNF165
	Search GNC Networks for RNF165
	SABiosciences Custom PCR Arrays for RNF165

Search Tocris compounds for RNF165

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RNF165 antibodies
	RNF165 lysates

	Search for Antibodies for RNF165 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for RNF165
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RNF165 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RNF165

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF165

	SwitchGear 3'UTR luciferase reporter plasmids for RNF165
	SwitchGear Promoter luciferase reporter plasmids for RNF165

Search ThermoFisher Antibodies for RNF165

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat RNF165

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RNF165 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

RNF165 Gene

ring finger protein 165

Aliases
for RNF165 gene

Summaries
for RNF165 gene

Genomic Views
for RNF165 gene

Proteins
for RNF165 gene

Protein Domains /
Families
for RNF165 gene

Function
for RNF165 gene

Pathways & Interactions
for RNF165 gene

Drugs & Compounds
for RNF165 gene

Transcripts
for RNF165 gene

Expression
for RNF165 gene

Orthologs
for RNF165 gene

Paralogs
for RNF165 gene

Genomic Variants
for RNF165 gene

Disorders / Diseases
for RNF165 gene

Publications
for RNF165 gene

External Searches for RNF165 gene

Genome Databases showing RNF165 gene

Other Databases showing RNF165 gene

Specialized Databases showing RNF165 gene

Intellectual Property
for RNF165 gene

Products
for RNF165 gene

View Random Gene

Advanced Search

Export list of displayed genes

RNF165 Gene

ring finger protein 165

Aliasesfor RNF165 gene

Summariesfor RNF165 gene

Genomic Viewsfor RNF165 gene

Proteinsfor RNF165 gene

Protein Domains /Familiesfor RNF165 gene

Functionfor RNF165 gene

Pathways & Interactionsfor RNF165 gene

Drugs & Compoundsfor RNF165 gene

Transcriptsfor RNF165 gene

Expression for RNF165 gene

Orthologsfor RNF165 gene

Paralogsfor RNF165 gene

Genomic Variantsfor RNF165 gene

Disorders / Diseasesfor RNF165 gene

Publicationsfor RNF165 gene

External Searches for RNF165 gene

Genome Databases showing RNF165 gene

Other Databases showing RNF165 gene

Specialized Databases showing RNF165 gene

Intellectual Propertyfor RNF165 gene

Productsfor RNF165 gene

View Random Gene

Aliases
for RNF165 gene

Summaries
for RNF165 gene

Genomic Views
for RNF165 gene

Proteins
for RNF165 gene

Protein Domains /
Families
for RNF165 gene

Function
for RNF165 gene

Pathways & Interactions
for RNF165 gene

Drugs & Compounds
for RNF165 gene

Transcripts
for RNF165 gene

Expression
for RNF165 gene

Orthologs
for RNF165 gene

Paralogs
for RNF165 gene

Genomic Variants
for RNF165 gene

Disorders / Diseases
for RNF165 gene

Publications
for RNF165 gene

Intellectual Property
for RNF165 gene

Products
for RNF165 gene