Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RNF157 Gene

protein-coding GIFtS: 48
GCID: GC17M074138

ring finger protein 157

Explore 1 disease affiliated with
RNF157 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ring Finger Protein 157¹ ²
KIAA1917¹ ³

External Ids:	HGNC: 29402¹	Entrez Gene: 114804²	Ensembl: ENSG00000141576⁷	UniProtKB: Q96PX1³

Export aliases for RNF157 gene to outside databases

Previous GC identifers: GC17M074738 GC17M071651 GC17M069567

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.1 NT_010783.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RNF157 gene promoter:
Bach1 COUP-TF1 COUP HNF-4alpha2 Evi-1 GATA-1 HNF-4alpha1 JunD COUP-TF NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RNF157 promoter sequence

Search SABiosciences Chromatin IP Primers for RNF157

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF157

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.3

RNF157 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF157 gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M074138: view genomic region (about GC identifiers)

Start:	74,138,534 bp from pter	End:	74,236,454 bp from pter
Size:	97,921 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RN157_HUMAN, Q96PX1 (See protein sequence)

Recommended Name: RING finger protein 157

Size: 679 amino acids; 73579 Da

Sequence caution: Sequence=BAB67810.2; Type=Erroneous initiation; Sequence=BAB71053.1; Type=Erroneous initiation;

Sequence=BAC03669.1; Type=Erroneous initiation;

Secondary accessions: Q8NB72 Q96N56

Alternative splicing: 2 isoforms: Q96PX1-1 Q96PX1-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for RNF157: NX_Q96PX1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96PX1

RNF157 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_443148.1

ENSEMBL proteins:

ENSP00000269391 ENSP00000321837 ENSP00000468099 ENSP00000467096 ENSP00000465543

Human Recombinant Protein Products for RNF157:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for RNF157
	GenScript Custom Purified and Recombinant Proteins Services for RNF157
	Novus Biologicals RNF157 Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for RNF157

RNF157 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for RNF157
	GenScript Custom Superior Antibodies Services for RNF157
	Novus Biologicals RNF157 Antibodies
	Abcam antibodies for RNF157
	Uscn Antibodies for RNF157
	Search ThermoFisher Antibodies for RNF157

Assay Products for RNF157:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for RNF157
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for RNF157

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RNF157 for domains About GeneDecksing

2 InterPro domains/families:

IPR001841 Znf_RING

IPR013083 Znf_RING/FYVE/PHD

Graphical View of Domain Structure for InterPro Entry Q96PX1

ProtoNet protein and cluster: Q96PX1

1 Blocks protein family: IPB001841 Zn-finger

UniProtKB/Swiss-Prot: RN157_HUMAN, Q96PX1

Similarity: Contains 1 RING-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008270	zinc ion binding	IEA	--

RNF157 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for RNF157:

Increased cell death HMECs cel

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RNF157

miRNA Products:		OriGene 3'-UTR Clone: RNF157 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF157
		8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF157 (see all 49):
		hsa-miR-21* hsa-miR-579 hsa-miR-4328 hsa-miR-25 hsa-miR-30d hsa-miR-10b* hsa-miR-4314 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: RNF157 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		Browse OriGene 29mer shRNA kits Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF157
		Sirion Biotech Custom design and validation of potent shRNA sequences against RNF157

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for RNF157
			Sirion Biotech Customized adenovirus for overexpression of RNF157 Sirion Biotech Customized adenovirus for potent knockdown of RNF157

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RNF157 (NM_052916)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF157
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF157

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for RNF157
		Search LifeMap BioReagents cell lines for RNF157
		Sirion Biotech Customized stable knockdown cell line services for RNF157 Sirion Biotech Customized inducible knockdown cell line services for RNF157 Sirion Biotech Customized stable overexpressing cell line services for RNF157 Sirion Biotech Customized inducible overexpressing cell line services for RNF157

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF157

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RNF157

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for RNF157 (Q96PX1³ ENSP00000269391⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBE2G2	P60604³, ENSP00000338348⁴	I2D: score=2 STRING: ENSP00000338348

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RNF157
Search CenterWatch for drugs/clinical trials and news about RNF157 / RN157

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RNF157 gene:

NM_052916.2

Unigene Cluster for RNF157:

Ring finger protein 157

Hs.500643 [show with all ESTs]

Unigene Representative Sequence: NM_052916

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000269391(uc002jqz.3 uc002jra.3) ENST00000589912 ENST00000319945

ENST00000589317 ENST00000591355 ENST00000592869 ENST00000593155 ENST00000591615

ENST00000592271

miRNA Products:		OriGene 3'-UTR Clone: RNF157 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF157
		8/49 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF157 (see all 49):
		hsa-miR-21* hsa-miR-579 hsa-miR-4328 hsa-miR-25 hsa-miR-30d hsa-miR-10b* hsa-miR-4314 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: RNF157 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		Browse OriGene 29mer shRNA kits Browse OriGene siRNA
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF157
		Sirion Biotech Custom design and validation of potent shRNA sequences against RNF157

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: RNF157 (NM_052916)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF157
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF157

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF157 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat RNF157
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF157
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF157

Additional cDNA sequence:

AB067504.2 AK055949.1 AK091467.1 BC004231.2 BC042501.1

8 DOTS entries:

DT.430822 DT.454843 DT.100876026 DT.91723928 DT.92040393 DT.95168602 DT.100678850 DT.95168601

24/142 AceView cDNA sequences (see all 142):

BQ477762 CD673749 AI950282 BM310065 BM783349 AA452336 BF791875 AA609142

BE277439 BM725674 AI522091 BC004231 BX109616 BE672075 AA350402 BM273245

AK055949 BQ431935 BF056204 BM722923 BM310333 BM551639 AW445110 AA371906

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RNF157 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTCTTAAAA

About this image

RNF157 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See RNF157 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF157

SOURCE GeneReport for Unigene cluster: Hs.500643

SABiosciences Custom PCR Arrays for RNF157

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF157 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat RNF157
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF157
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF157

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF157

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for RNF157 gene from 7/24 species (see all 24) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	RNF157¹	ring finger protein 157	78.48(n) 84.39(a)		429219 XM_426775.3 XP_426775.3
lizard (Anolis carolinensis)	Reptilia	RNF157⁶	--	83(a)	1 ↔ 1	2(112954826-112986784)
zebrafish (Danio rerio)	Actinopterygii	rnf157¹	ring finger protein 157	69.63(n) 71.34(a)		555415 XM_677914.4 XP_683006.4
fruit fly (Drosophila melanogaster)	Insecta	CG9941¹	CG9941	49.17(n) 42.91(a)		32330 NM_132687.1 NP_572915.1
worm (Caenorhabditis elegans)	Secernentea	C11H1.3¹	Protein C11H1.3	45.69(n) 36.84(a)		181537 NM_077984.3 NP_510385.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G19080¹	RING/U-box domain-containing protein	48.51(n) 39.43(a)		832027 NM_121913.2 NP_197409.1
rice (Oryza sativa)	Liliopsida	Os05g0397650¹	hypothetical protein	49.17(n) 39.11(a)		9266835 NM_001187485.1 NP_001174414.1

ENSEMBL Gene Tree for RNF157 (if available)
TreeFam Gene Tree for RNF157 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RNF157 gene

MGRN1²

1 SIMAP similar gene for RNF157 using alignment to 5 protein entries: RN157_HUMAN (see all proteins):

MGRN1

RNF157 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs78399909^1,2		--	74139568(+)	`GGTTAC/TTGCTC`	2	--	ut3¹ int¹		0	--	--	--	--
rs75633162^1,2	F	--	74139602(+)	`AGGGGC/TGGGAA`	2	--	int¹ ut3¹		1		WA	118
rs73345576^1,2	C	--	74139626(+)	`AGGAAG/TGAAAG`	2	--	int¹ ut3¹		2		WA	120
rs2598427^1,2	C,F,A	--	74139694(-)	`GGGCCT/CGTCGT`	2	--	int¹ ut3¹		11		NA WA CSA EA	372
rs137950728^1,2		--	74140176(+)	`AGATGC/GGGGCA`	2	--	int¹ ut3¹		0	--	--	--	--
rs73996148^1,2	C	--	74140373(+)	`ATCTTA/CACTGG`	2	--	int¹ ut3¹		2		WA	120
rs189452055^1,2		--	74140374(+)	`TCTTAA/GCTGGG`	2	--	ut3¹ int¹		0	--	--	--	--
rs200215015^1,2	C	--	74140405(+)	`TCCTTC/TTTTTT`	2	--	int¹ ut3¹		0	--	--	--	--
rs11653252^1,2	H	--	74140426(+)	`ctctgA/Tcgccc`	2	--	ut3¹ int¹ ese³		0	--	--	--	--
rs143901148^1,2		--	74140463(+)	`GGCTCA/TCTGCA`	2	--	ut3¹ int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for RNF157 (74138534 - 74236454 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for RNF157
2 CNVs: 73018 5032

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF157

DNA2.0 Custom Variant and Variant Library Synthesis for RNF157

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RNF157 for disorders About GeneDecksing

1 disease for RNF157: About MalaCards

malaria

Human Genome Epidemiology (HuGE) Navigator: RNF157 (5 documents)

Export disorders for RNF157 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RNF157 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RNF157)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)^{1, 2, 3} Nagase T....Ohara O. (2001)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Strategy for comprehensive identification of human N-myristoylated proteins using an insect cell-free protein synthesis system. (PubMed id 20213681)² Suzuki T.... Utsumi T. (2010)
Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)¹ Flachsbart F....Nebel A. (2010)
Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)¹ van Wijk S.J....Timmers H.T. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)² Nakajima D.... Nagase T. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 114804	HGNC: 29402	AceView: RNF157	Ensembl:ENSG00000141576	euGenes: HUgn114804
ECgene: RNF157	H-InvDB: RNF157

(According to HUGE)
About This Section

HUGE: KIAA1917

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for RNF157	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RNF157 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for RNF157 gene:
Search GeneIP for patents involving RNF157

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		Browse OriGene shRNA RFPs
	Browse OriGene 29mer shRNA kits in GFP-retroviral vector		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF157
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	Browse OriGene siRNAs		OriGene 3'-UTR Clone for RNF157
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF157
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for RNF157		OriGene Custom Protein Services for RNF157
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat RNF157
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF157
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF157
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat RNF157
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF157
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF157

	GenScript Custom Purified and Recombinant Proteins Services for RNF157		GenScript cDNA clones with any tag delivered in your preferred vector for RNF157
	GenScript Custom Assay Services for RNF157		GenScript Custom Superior Antibodies Services for RNF157
	GenScript Custom overexpressing Cell Line Services for RNF157		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in RNF157 promoter
	Search Chromatin IP Primers for RNF157
	RT² qPCR Primer Assay in human, mouse / rat RNF157
	Search GNC Networks for RNF157
	SABiosciences Custom PCR Arrays for RNF157

Search Tocris compounds for RNF157

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	RNF157 antibodies
	RNF157 proteins

	Antibodies for RNF157
	See all of Abcam's Antibodies, Kits and Proteins for RNF157
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

RNF157 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for RNF157

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF157

	SwitchGear 3'UTR luciferase reporter plasmids for RNF157
	SwitchGear Promoter luciferase reporter plasmids for RNF157

Search ThermoFisher Antibodies for RNF157

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF157

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for RNF157

Sirion Biotech Customized:

	stable knockdown cell line services for RNF157
	inducible knockdown cell line services for RNF157
	design and validation of potent shRNA sequences against RNF157
	adenovirus for potent knockdown of RNF157
	adenovirus for overexpression of RNF157
	stable overexpressing cell line services for RNF157
	inducible overexpressing cell line services for RNF157

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes RNF157 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

RNF157 Gene

ring finger protein 157

Aliases
for RNF157 gene

Summaries
for RNF157 gene

Genomic Views
for RNF157 gene

Proteins
for RNF157 gene

Protein Domains /
Families
for RNF157 gene

Function
for RNF157 gene

Pathways & Interactions
for RNF157 gene

Drugs & Compounds
for RNF157 gene

Transcripts
for RNF157 gene

Expression
for RNF157 gene

Orthologs
for RNF157 gene

Paralogs
for RNF157 gene

Genomic Variants
for RNF157 gene

Disorders / Diseases
for RNF157 gene

Publications
for RNF157 gene

External Searches for RNF157 gene

Genome Databases showing RNF157 gene

Other Databases showing RNF157 gene

Specialized Databases showing RNF157 gene

Intellectual Property
for RNF157 gene

Products
for RNF157 gene

View Random Gene

Advanced Search

Export list of displayed genes

RNF157 Gene

ring finger protein 157

Aliasesfor RNF157 gene

Summariesfor RNF157 gene

Genomic Viewsfor RNF157 gene

Proteinsfor RNF157 gene

Protein Domains /Familiesfor RNF157 gene

Functionfor RNF157 gene

Pathways & Interactionsfor RNF157 gene

Drugs & Compoundsfor RNF157 gene

Transcriptsfor RNF157 gene

Expression for RNF157 gene

Orthologsfor RNF157 gene

Paralogsfor RNF157 gene

Genomic Variantsfor RNF157 gene

Disorders / Diseasesfor RNF157 gene

Publicationsfor RNF157 gene

External Searches for RNF157 gene

Genome Databases showing RNF157 gene

Other Databases showing RNF157 gene

Specialized Databases showing RNF157 gene

Intellectual Propertyfor RNF157 gene

Productsfor RNF157 gene

View Random Gene

Aliases
for RNF157 gene

Summaries
for RNF157 gene

Genomic Views
for RNF157 gene

Proteins
for RNF157 gene

Protein Domains /
Families
for RNF157 gene

Function
for RNF157 gene

Pathways & Interactions
for RNF157 gene

Drugs & Compounds
for RNF157 gene

Transcripts
for RNF157 gene

Expression
for RNF157 gene

Orthologs
for RNF157 gene

Paralogs
for RNF157 gene

Genomic Variants
for RNF157 gene

Disorders / Diseases
for RNF157 gene

Publications
for RNF157 gene

Intellectual Property
for RNF157 gene

Products
for RNF157 gene