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Aliases for RNF151 Gene

Aliases for RNF151 Gene

  • Ring Finger Protein 151 2 3 5

External Ids for RNF151 Gene

Previous GeneCards Identifiers for RNF151 Gene

  • GC16P001957
  • GC16P001958
  • GC16P001959
  • GC16P001963
  • GC16P002017
  • GC16P002019
  • GC16P001940
  • GC16P002024
  • GC16P002028
  • GC16P002047
  • GC16P002054
  • GC16P002077
  • GC16P002092
  • GC16P002113
  • GC16P001978
  • GC16P001986
  • GC16P001992
  • GC16P001999
  • GC16P002008
  • GC16P002131

Summaries for RNF151 Gene

GeneCards Summary for RNF151 Gene

RNF151 (Ring Finger Protein 151) is a Protein Coding gene. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is RNF41.

UniProtKB/Swiss-Prot for RNF151 Gene

  • May be involved in acrosome formation of spermatids.

Additional gene information for RNF151 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF151 Gene

Genomics for RNF151 Gene

Regulatory Elements for RNF151 Gene

Enhancers for RNF151 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H001956 0.3 FANTOM5 83.9 -9.9 -9933 0 RNF151 ENSG00000255513 BRICD5 PRSS30P RPL3L MSRB1
GH16H002003 2 FANTOM5 Ensembl ENCODE dbSUPER 11.5 +40.4 40399 7 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF207 TBL3 CRAMP1 ZNF598 ENSG00000226890 ENSG00000255513 ENSG00000200059 AMDHD2 ENSG00000261240 ENSG00000260051 ENSG00000261505
GH16H002147 2 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +189.0 188968 17 MLX ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC CRAMP1 ENSG00000260051 ENSG00000261505 TELO2 TBL3 UNKL E4F1 TSC2 SRRM2 ZNF213-AS1
GH16H000986 1.2 ENCODE dbSUPER 11.3 -985.7 -985678 0 ZNF473 ZNF493 ZSCAN4 ZNF133 GLI4 ZNF2 EGR1 ZNF366 SCRT2 ZNF416 ENSG00000261505 CRAMP1 WDR90 UBE2I TBL3 ENSG00000260051 ENSG00000260954 ENSG00000255513 SNORA64 UNKL
GH16H000981 1.2 ENCODE dbSUPER 11.3 -985.3 -985348 0 ZNF493 ZNF133 GLI4 ZNF2 GLIS2 ZNF416 KLF7 ZNF548 SP3 MCM3 WDR90 CRAMP1 ENSG00000261505 UBE2I JMJD8 TELO2 ENSG00000260954 UNKL ENSG00000260051 WDR24
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNF151 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF151 Gene

Chromosome:
16
Start:
1,966,823 bp from pter
End:
1,968,975 bp from pter
Size:
2,153 bases
Orientation:
Plus strand

Genomic View for RNF151 Gene

Genes around RNF151 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF151 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF151 Gene

Proteins for RNF151 Gene

  • Protein details for RNF151 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2KHN1-RN151_HUMAN
    Recommended name:
    RING finger protein 151
    Protein Accession:
    Q2KHN1
    Secondary Accessions:
    • Q8NHS5

    Protein attributes for RNF151 Gene

    Size:
    245 amino acids
    Molecular mass:
    27412 Da
    Quaternary structure:
    • Interacts with DTNBP1.

neXtProt entry for RNF151 Gene

Post-translational modifications for RNF151 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF151 Gene

No data available for DME Specific Peptides for RNF151 Gene

Domains & Families for RNF151 Gene

Gene Families for RNF151 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RNF151 Gene

Suggested Antigen Peptide Sequences for RNF151 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RNF151: view

No data available for UniProtKB/Swiss-Prot for RNF151 Gene

Function for RNF151 Gene

Molecular function for RNF151 Gene

UniProtKB/Swiss-Prot Function:
May be involved in acrosome formation of spermatids.

Gene Ontology (GO) - Molecular Function for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF151: view
genes like me logo Genes that share phenotypes with RNF151: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for RNF151
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF151 Gene

Localization for RNF151 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF151 Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNF151 gene
Compartment Confidence
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with RNF151: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for RNF151 Gene

Pathways & Interactions for RNF151 Gene

SuperPathways for RNF151 Gene

No Data Available

Interacting Proteins for RNF151 Gene

Gene Ontology (GO) - Biological Process for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with RNF151: view

No data available for Pathways by source and SIGNOR curated interactions for RNF151 Gene

Drugs & Compounds for RNF151 Gene

No Compound Related Data Available

Transcripts for RNF151 Gene

mRNA/cDNA for RNF151 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF151 Gene

Ring finger protein 151:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for RNF151
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for RNF151 Gene

No ASD Table

Relevant External Links for RNF151 Gene

GeneLoc Exon Structure for
RNF151
ECgene alternative splicing isoforms for
RNF151

Expression for RNF151 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RNF151 Gene

mRNA differential expression in normal tissues according to GTEx for RNF151 Gene

This gene is overexpressed in Testis (x51.6).

Protein differential expression in normal tissues from HIPED for RNF151 Gene

This gene is overexpressed in Monocytes (34.8) and Pancreatic juice (34.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RNF151 Gene



Protein tissue co-expression partners for RNF151 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RNF151 Gene:

RNF151

SOURCE GeneReport for Unigene cluster for RNF151 Gene:

Hs.99354
genes like me logo Genes that share expression patterns with RNF151: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RNF151 Gene

Orthologs for RNF151 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF151 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RNF151 33 34
  • 98.5 (n)
dog
(Canis familiaris)
Mammalia RNF151 33 34
  • 83.67 (n)
cow
(Bos Taurus)
Mammalia RNF151 33 34
  • 81.53 (n)
rat
(Rattus norvegicus)
Mammalia Rnf151 33
  • 79.94 (n)
mouse
(Mus musculus)
Mammalia Rnf151 33 16 34
  • 77.83 (n)
oppossum
(Monodelphis domestica)
Mammalia RNF151 34
  • 66 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia RNF151 34
  • 8 (a)
OneToOne
chicken
(Gallus gallus)
Aves RNF151 34
  • 22 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RNF151 34
  • 16 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf151 33
  • 60.52 (n)
zebrafish
(Danio rerio)
Actinopterygii LOC100004674 33
  • 54.69 (n)
RNF151 34
  • 35 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG9014 34
  • 15 (a)
OneToOne
Species where no ortholog for RNF151 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF151 Gene

ENSEMBL:
Gene Tree for RNF151 (if available)
TreeFam:
Gene Tree for RNF151 (if available)

Paralogs for RNF151 Gene

Paralogs for RNF151 Gene

(5) SIMAP similar genes for RNF151 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RNF151: view

Variants for RNF151 Gene

Sequence variations from dbSNP and Humsavar for RNF151 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1001374265 -- 1,968,737(+) TCCTG(C/T)GGCGT reference, missense
rs1001591131 -- 1,966,634(+) CCTGG(G/T)CTCAA upstream-variant-2KB
rs1001755957 -- 1,964,845(+) GGGAA(A/G)CAGCT upstream-variant-2KB
rs1002649697 -- 1,967,572(+) TGCAG(A/G)CCCCG intron-variant
rs1003605698 -- 1,968,716(+) GTCGG(A/C)CCCTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RNF151 Gene

Variant ID Type Subtype PubMed ID
dgv336n27 CNV loss 19166990
dgv4858n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
nsv1160329 CNV deletion 26073780
nsv471070 CNV gain 18288195
nsv571179 CNV loss 21841781
nsv833120 CNV loss 17160897
nsv952901 CNV deletion 24416366

Variation tolerance for RNF151 Gene

Residual Variation Intolerance Score: 88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.18; 61.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RNF151 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
RNF151

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNF151 Gene

Disorders for RNF151 Gene

Relevant External Links for RNF151

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNF151

No disorders were found for RNF151 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF151 Gene

Publications for RNF151 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis. (PMID: 22992278) Hou X … Han C (BMC genomics 2012) 3 60
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 60

Products for RNF151 Gene

Sources for RNF151 Gene

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