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Aliases for RNF151 Gene

Aliases for RNF151 Gene

  • Ring Finger Protein 151 2 3 5

External Ids for RNF151 Gene

Previous GeneCards Identifiers for RNF151 Gene

  • GC16P001957
  • GC16P001958
  • GC16P001959
  • GC16P001963
  • GC16P002017
  • GC16P002019
  • GC16P001940
  • GC16P002024
  • GC16P002028
  • GC16P002047
  • GC16P002054
  • GC16P002077
  • GC16P002092
  • GC16P002113
  • GC16P001978
  • GC16P001986

Summaries for RNF151 Gene

GeneCards Summary for RNF151 Gene

RNF151 (Ring Finger Protein 151) is a Protein Coding gene. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is RNF41.

UniProtKB/Swiss-Prot for RNF151 Gene

  • May be involved in acrosome formation of spermatids.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF151 Gene

Genomics for RNF151 Gene

Regulatory Elements for RNF151 Gene

Enhancers for RNF151 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNF151 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF151 Gene

1,966,823 bp from pter
1,968,975 bp from pter
2,153 bases
Plus strand

Genomic View for RNF151 Gene

Genes around RNF151 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF151 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF151 Gene

Proteins for RNF151 Gene

  • Protein details for RNF151 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 151
    Protein Accession:
    Secondary Accessions:
    • Q8NHS5

    Protein attributes for RNF151 Gene

    245 amino acids
    Molecular mass:
    27412 Da
    Quaternary structure:
    • Interacts with DTNBP1.

neXtProt entry for RNF151 Gene

Proteomics data for RNF151 Gene at MOPED

Post-translational modifications for RNF151 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF151 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF151 Gene

Domains & Families for RNF151 Gene

Gene Families for RNF151 Gene

Protein Domains for RNF151 Gene

Suggested Antigen Peptide Sequences for RNF151 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 RING-type zinc finger.
  • Contains 1 RING-type zinc finger.
  • Contains 1 TRAF-type zinc finger.
genes like me logo Genes that share domains with RNF151: view

Function for RNF151 Gene

Molecular function for RNF151 Gene

UniProtKB/Swiss-Prot Function:
May be involved in acrosome formation of spermatids.

Gene Ontology (GO) - Molecular Function for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity IEA --
genes like me logo Genes that share ontologies with RNF151: view
genes like me logo Genes that share phenotypes with RNF151: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF151 Gene

Localization for RNF151 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF151 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Jensen Localization Image for RNF151 Gene COMPARTMENTS Subcellular localization image for RNF151 gene
Compartment Confidence
nucleus 5
cytosol 3

No data available for Gene Ontology (GO) - Cellular Components for RNF151 Gene

Pathways & Interactions for RNF151 Gene

SuperPathways for RNF151 Gene

No Data Available

Interacting Proteins for RNF151 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000456566 for RNF151 Gene via STRING

Gene Ontology (GO) - Biological Process for RNF151 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016567 protein ubiquitination IEA --
genes like me logo Genes that share ontologies with RNF151: view

No data available for Pathways by source and SIGNOR curated interactions for RNF151 Gene

Drugs & Compounds for RNF151 Gene

No Compound Related Data Available

Transcripts for RNF151 Gene

mRNA/cDNA for RNF151 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF151 Gene

Ring finger protein 151:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNF151 Gene

No ASD Table

Relevant External Links for RNF151 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF151 Gene

mRNA expression in normal human tissues for RNF151 Gene

mRNA differential expression in normal tissues according to GTEx for RNF151 Gene

This gene is overexpressed in Testis (x51.6).

Protein differential expression in normal tissues from HIPED for RNF151 Gene

This gene is overexpressed in Monocytes (34.8) and Pancreatic juice (34.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RNF151 Gene

SOURCE GeneReport for Unigene cluster for RNF151 Gene Hs.99354

genes like me logo Genes that share expression patterns with RNF151: view

Protein tissue co-expression partners for RNF151 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RNF151 Gene

Orthologs for RNF151 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF151 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RNF151 35
  • 81.53 (n)
  • 74.03 (a)
RNF151 36
  • 71 (a)
(Canis familiaris)
Mammalia RNF151 35
  • 83.67 (n)
  • 77.46 (a)
RNF151 36
  • 77 (a)
(Mus musculus)
Mammalia Rnf151 35
  • 77.83 (n)
  • 71.3 (a)
Rnf151 16
Rnf151 36
  • 69 (a)
(Pan troglodytes)
Mammalia RNF151 35
  • 98.5 (n)
  • 96.73 (a)
RNF151 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Rnf151 35
  • 79.94 (n)
  • 76.11 (a)
(Monodelphis domestica)
Mammalia RNF151 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia RNF151 36
  • 8 (a)
(Gallus gallus)
Aves RNF151 36
  • 22 (a)
(Anolis carolinensis)
Reptilia RNF151 36
  • 16 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf151 35
  • 60.52 (n)
  • 45.83 (a)
(Danio rerio)
Actinopterygii LOC100004674 35
  • 54.69 (n)
  • 45.51 (a)
RNF151 36
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG9014 36
  • 15 (a)
Species with no ortholog for RNF151:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RNF151 Gene

Gene Tree for RNF151 (if available)
Gene Tree for RNF151 (if available)

Paralogs for RNF151 Gene

Paralogs for RNF151 Gene

(5) SIMAP similar genes for RNF151 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RNF151: view

Variants for RNF151 Gene

Sequence variations from dbSNP and Humsavar for RNF151 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs13332256 -- 1,966,860(+) TGTGG(A/G)GCTGC upstream-variant-2KB, utr-variant-5-prime
rs62038783 -- 1,967,109(+) GGGCC(C/G)TAACC intron-variant
rs62038784 -- 1,968,579(+) GCACC(A/G)GCAGC reference, missense
rs28400336 -- 1,969,212(+) GCAGG(C/T)GCCTG downstream-variant-500B
rs62617079 -- 1,968,911(+) CCAAC(A/G)TACCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RNF151 Gene

Variant ID Type Subtype PubMed ID
esv2422427 CNV Duplication 17116639
dgv2540n71 CNV Loss 21882294
dgv2544n71 CNV Loss 21882294
dgv2545n71 CNV Loss 21882294
nsv833120 CNV Loss 17160897
nsv905048 CNV Loss 21882294
dgv2546n71 CNV Loss 21882294
dgv2547n71 CNV Loss 21882294
dgv2548n71 CNV Gain 21882294
dgv2549n71 CNV Loss 21882294
dgv2550n71 CNV Loss 21882294
nsv905061 CNV Loss 21882294
dgv2551n71 CNV Loss 21882294
nsv471070 CNV Gain 18288195
nsv905070 CNV Gain+Loss 21882294
dgv2552n71 CNV Gain+Loss 21882294
dgv336n27 CNV Loss 19166990
nsv905076 CNV Gain 21882294
dgv2553n71 CNV Loss 21882294

Variation tolerance for RNF151 Gene

Residual Variation Intolerance Score: 88% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.18; 61.77% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RNF151 Gene

Disorders for RNF151 Gene

Relevant External Links for RNF151

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF151 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF151 Gene

Publications for RNF151 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Mining and characterization of ubiquitin E3 ligases expressed in the mouse testis. (PMID: 22992278) Hou X. … Han C. (BMC Genomics 2012) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for RNF151 Gene

Sources for RNF151 Gene