RNF151 Gene
protein-coding GIFtS: 38
GCID: GC16P002077
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ring finger protein 151
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Aliases
for RNF151 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ring Finger Protein 1511 2 |
Export aliases for RNF151 gene to outside databasesPrevious GC identifers: GC16P001957 GC16P001958 GC16P001959 GC16P001963 GC16P002017 GC16P002019 GC16P001940 GC16P002024 GC16P002028 GC16P002047 GC16P002054 |
Summaries
for RNF151 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: RN151_HUMAN, Q2KHN1Function: May be involved in acrosome formation of spermatids
|
Genomic Views
for RNF151 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNF151 gene promoter:
SRF NF-1/L NF-1 MAZR Pax-5 SRF (504 AA) AP-4 NF-kappaB1 c-Ets-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNF151
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF151 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3RNF151 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P002077: view genomic region
(about GC identifiers)
Start:
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2,016,824 bp from pter |
End:
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2,018,976 bp from pter |
Size:
|
2,153 bases |
Orientation:
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plus strand |
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Proteins
for RNF151 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: RN151_HUMAN, Q2KHN1 (See
protein sequence)Recommended Name: RING finger protein 151 Size: 245 amino acids; 27412 Da
Subunit: Interacts with DTNBP1 (By similarity)
Subcellular location: Cytoplasm (By similarity). Nucleus (By similarity)
Secondary accessions: Q8NHS5Explore the universe of human proteins at neXtProt for RNF151: NX_Q2KHN1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q2KHN1
RNF151 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_777563.2
ENSEMBL proteins: ENSP00000454886 ENSP00000456566 ENSP00000325794
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
RNF151 for ontologies About GeneDecksing
RNF151 Antibody Products:
Assay Products for RNF151: |
Protein
Domains /
Families
for RNF151 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNF151 for domains About GeneDecksing
5/7 InterPro domains/families (see all 7):Graphical View of Domain Structure for InterPro Entry Q2KHN1ProtoNet protein and cluster: Q2KHN1 UniProtKB/Swiss-Prot: RN151_HUMAN, Q2KHN1Similarity: Contains 1 RING-type zinc fingerSimilarity: Contains 1 TRAF-type zinc finger |
Function
for RNF151 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: RN151_HUMAN, Q2KHN1Function: May be involved in acrosome formation of spermatids
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: RNF151 (NM_174903) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF151 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF151 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004842 | ubiquitin-protein ligase activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
RNF151 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for RNF151:
|
Pathways & Interactions
for RNF151 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF151
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007283 | spermatogenesis |
IEA | -- | | GO:0030154 | cell differentiation |
IEA | -- |
RNF151 for ontologies About GeneDecksing
|
Drugs & Compounds
for RNF151 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RNF151
Search CenterWatch for drugs/clinical trials and news about RNF151 / RN151
|
Transcripts
for RNF151 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNF151 gene: NM_174903.4 Unigene Cluster for RNF151: Ring finger protein 151 Hs.99354 [show with all ESTs]Unigene Representative Sequence: BI4613483 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000569210 ENST00000569714(uc002cnt.1) ENST00000321392
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RNF151 (NM_174903) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF151 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF151 |
Additional cDNA sequence: BC029501.2 BC113014.2 2 DOTS entries: DT.70105132 DT.120656710 13 AceView cDNA sequences: BC029501 BE552345 AW236968 BI829513 BX089545 BI461348 AI653299 AI916892 AJ457801 AI351074 BF057221 AA453999 AI798656
GeneLoc Exon Structure
|
Expression
for RNF151 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNF151 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCCTGGCC
About this image
See RNF151 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF151
SOURCE GeneReport for Unigene cluster: Hs.99354
SABiosciences Custom PCR Arrays for RNF151
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF151
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat RNF151 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF151 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF151 |
Orthologs
for RNF151 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for RNF151 gene from 2/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
RNF1516 |
Uncharacterized protein |
26(a) |
1 ↔ 1 |
2(130893417-130900125) |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1000046741 |
RING finger protein 151-like |
50.41(n)
39.51(a) |
|
100004674 XM_001343883.1 XP_001343919.1 |
ENSEMBL Gene Tree for RNF151 (if available)
TreeFam Gene Tree for RNF151 (if available) |
Paralogs
for RNF151 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNF151 gene
- RNF412
5 SIMAP similar genes for RNF151 using alignment to 2 protein entries: RN151_HUMAN (see all proteins):RNF135 RNF138 TRIM39 TRIM59 RNF41
RNF151 for paralogs About GeneDecksing
|
Genomic Variants
for RNF151 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for RNF151 (2016824 - 2018976 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for RNF151
4 CNVs: 53306 5329 29656 4917 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF151 |
|
Disorders
/ Diseases
for RNF151 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for RNF151 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNF151 gene integrated from 9 sources:
(articles sorted by number of sources associating them with RNF151) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Mining and characterization of ubiquitin E3 ligases ex pressed in the mouse testis. (PubMed id 22992278)1 Hou X....Han C. (2012)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
|
External Searches for RNF151 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing RNF151 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNF151 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNF151 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNF151 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for RNF151 gene:
Search GeneIP for patents involving RNF151
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RNF151 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for RNF151 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF151 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF151 | | | OriGene Protein Over-expression Lysate for RNF151 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF151 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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 | | | RNF151 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for RNF151 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF151 |
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