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Aliases for RNF150 Gene

Aliases for RNF150 Gene

  • Ring Finger Protein 150 2 3
  • KIAA1214 4

External Ids for RNF150 Gene

Previous GeneCards Identifiers for RNF150 Gene

  • GC04M142367
  • GC04M142364
  • GC04M142144
  • GC04M142006
  • GC04M141786
  • GC04M137516

Summaries for RNF150 Gene

GeneCards Summary for RNF150 Gene

RNF150 (Ring Finger Protein 150) is a Protein Coding gene. An important paralog of this gene is RNF167.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF150 Gene

Genomics for RNF150 Gene

Regulatory Elements for RNF150 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for RNF150 Gene

Chromosome:
4
Start:
140,859,807 bp from pter
End:
141,212,877 bp from pter
Size:
353,071 bases
Orientation:
Minus strand

Genomic View for RNF150 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNF150 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF150 Gene

Proteins for RNF150 Gene

  • Protein details for RNF150 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9ULK6-RN150_HUMAN
    Recommended name:
    RING finger protein 150
    Protein Accession:
    Q9ULK6
    Secondary Accessions:
    • Q3T1D0
    • Q6ZNW6

    Protein attributes for RNF150 Gene

    Size:
    438 amino acids
    Molecular mass:
    48072 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA86528.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RNF150 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RNF150 Gene

Proteomics data for RNF150 Gene at MOPED

Post-translational modifications for RNF150 Gene

  • Glycosylation at Asn 45, Asn 125, Asn 153, and Asn 186
  • Modification sites at PhosphoSitePlus

Other Protein References for RNF150 Gene

No data available for DME Specific Peptides for RNF150 Gene

Domains & Families for RNF150 Gene

Gene Families for RNF150 Gene

Protein Domains for RNF150 Gene

Suggested Antigen Peptide Sequences for RNF150 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9ULK6

UniProtKB/Swiss-Prot:

RN150_HUMAN :
  • Contains 1 PA (protease associated) domain.
  • Contains 1 RING-type zinc finger.
Domain:
  • Contains 1 PA (protease associated) domain.
Similarity:
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF150: view

Function for RNF150 Gene

Gene Ontology (GO) - Molecular Function for RNF150 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with RNF150: view
genes like me logo Genes that share phenotypes with RNF150: view

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNF150

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF150 Gene

Localization for RNF150 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF150 Gene

Membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for RNF150 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with RNF150: view

No data available for Subcellular locations from COMPARTMENTS for RNF150 Gene

Pathways & Interactions for RNF150 Gene

SuperPathways for RNF150 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for RNF150 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for RNF150 Gene

Drugs & Compounds for RNF150 Gene

No Compound Related Data Available

Transcripts for RNF150 Gene

Unigene Clusters for RNF150 Gene

Ring finger protein 150:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for RNF150

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF150 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1: - -
SP2:

Relevant External Links for RNF150 Gene

GeneLoc Exon Structure for
RNF150
ECgene alternative splicing isoforms for
RNF150

Expression for RNF150 Gene

mRNA expression in normal human tissues for RNF150 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RNF150 Gene

This gene is overexpressed in Heart - Left Ventricle (x4.3).

Protein differential expression in normal tissues from HIPED for RNF150 Gene

This gene is overexpressed in Ovary (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RNF150 Gene



SOURCE GeneReport for Unigene cluster for RNF150 Gene Hs.659104

genes like me logo Genes that share expression patterns with RNF150: view

Protein tissue co-expression partners for RNF150 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for RNF150 Gene

Orthologs for RNF150 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF150 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia RNF150 35
  • 90.33 (n)
  • 96.28 (a)
dog
(Canis familiaris)
Mammalia LOC607611 35
  • 88.66 (n)
  • 91.62 (a)
RNF150 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rnf150 35
  • 91 (n)
  • 94.51 (a)
Rnf150 16
Rnf150 36
  • 95 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia RNF150 35
  • 99.54 (n)
  • 99.32 (a)
RNF150 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Rnf150 35
  • 90.47 (n)
  • 94.05 (a)
oppossum
(Monodelphis domestica)
Mammalia RNF150 36
  • 93 (a)
OneToOne
chicken
(Gallus gallus)
Aves RNF150 35
  • 80.43 (n)
  • 85.45 (a)
RNF150 36
  • 90 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia RNF150 36
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf150 35
  • 77.54 (n)
  • 84.27 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC559804 35
  • 69.87 (n)
  • 72.36 (a)
rnf150a 36
  • 71 (a)
OneToMany
rnf150b 36
  • 70 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea H10E21.5 36
  • 26 (a)
OneToMany
Species with no ortholog for RNF150:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RNF150 Gene

ENSEMBL:
Gene Tree for RNF150 (if available)
TreeFam:
Gene Tree for RNF150 (if available)

Paralogs for RNF150 Gene

(8) SIMAP similar genes for RNF150 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RNF150: view

Variants for RNF150 Gene

Structural Variations from Database of Genomic Variants (DGV) for RNF150 Gene

Variant ID Type Subtype PubMed ID
nsv880167 CNV Gain 21882294
nsv830090 CNV Gain 17160897
nsv4530 CNV Insertion 18451855
nsv830091 CNV Loss 17160897
esv275310 CNV Gain+Loss 21479260
nsv527493 CNV Loss 19592680
nsv880168 CNV Loss 21882294
esv2728441 CNV Deletion 23290073
esv2728442 CNV Deletion 23290073
esv1188340 CNV Insertion 17803354
esv2511191 CNV Deletion 19546169
esv1974835 CNV Deletion 18987734
esv2672621 CNV Deletion 23128226
nsv880169 CNV Loss 21882294
nsv880170 CNV Loss 21882294
nsv509936 CNV Loss 20534489
nsv526770 CNV Loss 19592680

Variation tolerance for RNF150 Gene

Residual Variation Intolerance Score: 45.24% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.58; 56.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RNF150 Gene

HapMap Linkage Disequilibrium report
RNF150

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for RNF150 Gene

Disorders for RNF150 Gene

Relevant External Links for RNF150

Genetic Association Database (GAD)
RNF150
Human Genome Epidemiology (HuGE) Navigator
RNF150
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
RNF150
genes like me logo Genes that share disorders with RNF150: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF150 Gene

Publications for RNF150 Gene

  1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 67
  2. EGLN2 and RNF150 genetic variants are associated with chronic obstructive pulmonary disease risk in the Chinese population. (PMID: 25609945) Ding Y. … Jin T. (Int J Chron Obstruct Pulmon Dis 2015) 67
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 67
  4. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. (PMID: 23144326) Kim D.K. … Silverman E.K. (Am. J. Respir. Crit. Care Med. 2012) 67
  5. Genome-wide association study of conduct disorder symptomatology. (PMID: 20585324) Dick D.M. … Bierut L. (Mol. Psychiatry 2011) 67

Products for RNF150 Gene

Sources for RNF150 Gene

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