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Aliases for RNF150 Gene

Aliases for RNF150 Gene

  • Ring Finger Protein 150 2 3 5
  • KIAA1214 4

External Ids for RNF150 Gene

Previous GeneCards Identifiers for RNF150 Gene

  • GC04M142367
  • GC04M142364
  • GC04M142144
  • GC04M142006
  • GC04M141786
  • GC04M137516

Summaries for RNF150 Gene

GeneCards Summary for RNF150 Gene

RNF150 (Ring Finger Protein 150) is a Protein Coding gene. An important paralog of this gene is RNF167.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF150 Gene

Genomics for RNF150 Gene

Regulatory Elements for RNF150 Gene

Enhancers for RNF150 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNF150 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF150 Gene

140,859,807 bp from pter
141,212,877 bp from pter
353,071 bases
Minus strand

Genomic View for RNF150 Gene

Genes around RNF150 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF150 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF150 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF150 Gene

Proteins for RNF150 Gene

  • Protein details for RNF150 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 150
    Protein Accession:
    Secondary Accessions:
    • Q3T1D0
    • Q6ZNW6

    Protein attributes for RNF150 Gene

    438 amino acids
    Molecular mass:
    48072 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA86528.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for RNF150 Gene


neXtProt entry for RNF150 Gene

Proteomics data for RNF150 Gene at MOPED

Post-translational modifications for RNF150 Gene

  • Glycosylation at Asn 45, Asn 125, Asn 153, and Asn 186
  • Modification sites at PhosphoSitePlus

Other Protein References for RNF150 Gene

No data available for DME Specific Peptides for RNF150 Gene

Domains & Families for RNF150 Gene

Gene Families for RNF150 Gene

Protein Domains for RNF150 Gene

Suggested Antigen Peptide Sequences for RNF150 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 PA (protease associated) domain.
  • Contains 1 RING-type zinc finger.
  • Contains 1 PA (protease associated) domain.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF150: view

Function for RNF150 Gene

genes like me logo Genes that share phenotypes with RNF150: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RNF150 Gene

Localization for RNF150 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF150 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for RNF150 Gene COMPARTMENTS Subcellular localization image for RNF150 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for RNF150 Gene

Pathways & Interactions for RNF150 Gene

SuperPathways for RNF150 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF150 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNF150 Gene

Drugs & Compounds for RNF150 Gene

No Compound Related Data Available

Transcripts for RNF150 Gene

Unigene Clusters for RNF150 Gene

Ring finger protein 150:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNF150 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1: - -

Relevant External Links for RNF150 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF150 Gene

mRNA expression in normal human tissues for RNF150 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RNF150 Gene

This gene is overexpressed in Heart - Left Ventricle (x4.3).

Protein differential expression in normal tissues from HIPED for RNF150 Gene

This gene is overexpressed in Ovary (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for RNF150 Gene

SOURCE GeneReport for Unigene cluster for RNF150 Gene Hs.659104

genes like me logo Genes that share expression patterns with RNF150: view

Protein tissue co-expression partners for RNF150 Gene

- Elite partner

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for RNF150 Gene

Orthologs for RNF150 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF150 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RNF150 35
  • 90.33 (n)
  • 96.28 (a)
(Canis familiaris)
Mammalia LOC607611 35
  • 88.66 (n)
  • 91.62 (a)
RNF150 36
  • 92 (a)
(Mus musculus)
Mammalia Rnf150 35
  • 91 (n)
  • 94.51 (a)
Rnf150 16
Rnf150 36
  • 95 (a)
(Pan troglodytes)
Mammalia RNF150 35
  • 99.54 (n)
  • 99.32 (a)
RNF150 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Rnf150 35
  • 90.47 (n)
  • 94.05 (a)
(Monodelphis domestica)
Mammalia RNF150 36
  • 93 (a)
(Gallus gallus)
Aves RNF150 35
  • 80.43 (n)
  • 85.45 (a)
RNF150 36
  • 90 (a)
(Anolis carolinensis)
Reptilia RNF150 36
  • 83 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rnf150 35
  • 77.54 (n)
  • 84.27 (a)
(Danio rerio)
Actinopterygii LOC559804 35
  • 69.87 (n)
  • 72.36 (a)
rnf150a 36
  • 71 (a)
rnf150b 36
  • 70 (a)
(Caenorhabditis elegans)
Secernentea H10E21.5 36
  • 26 (a)
Species with no ortholog for RNF150:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RNF150 Gene

Gene Tree for RNF150 (if available)
Gene Tree for RNF150 (if available)

Paralogs for RNF150 Gene

(8) SIMAP similar genes for RNF150 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with RNF150: view

Variants for RNF150 Gene

Sequence variations from dbSNP and Humsavar for RNF150 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs171367 -- 141,192,969(-) ttttg(A/G)aagaa intron-variant
rs181378 -- 141,146,143(+) TACTT(A/T)GGGAT intron-variant
rs183055 -- 141,148,017(+) TTTCT(C/T)GTGTC intron-variant
rs187139 -- 141,146,323(+) TTCAA(C/T)GTTTT intron-variant
rs189567 -- 141,148,522(-) AGGTT(A/G)CAGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for RNF150 Gene

Variant ID Type Subtype PubMed ID
nsv880167 CNV Gain 21882294
nsv830090 CNV Gain 17160897
nsv4530 CNV Insertion 18451855
nsv830091 CNV Loss 17160897
esv275310 CNV Gain+Loss 21479260
nsv527493 CNV Loss 19592680
nsv880168 CNV Loss 21882294
esv2728441 CNV Deletion 23290073
esv2728442 CNV Deletion 23290073
esv1188340 CNV Insertion 17803354
esv2511191 CNV Deletion 19546169
esv1974835 CNV Deletion 18987734
esv2672621 CNV Deletion 23128226
nsv880169 CNV Loss 21882294
nsv880170 CNV Loss 21882294
nsv509936 CNV Loss 20534489
nsv526770 CNV Loss 19592680

Variation tolerance for RNF150 Gene

Residual Variation Intolerance Score: 45.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.58; 56.16% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for RNF150 Gene

Disorders for RNF150 Gene

Relevant External Links for RNF150

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF150 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF150 Gene

Publications for RNF150 Gene

  1. Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10574462) Nagase T. … Ohara O. (DNA Res. 1999) 2 3 4 67
  2. EGLN2 and RNF150 genetic variants are associated with chronic obstructive pulmonary disease risk in the Chinese population. (PMID: 25609945) Ding Y. … Jin T. (Int J Chron Obstruct Pulmon Dis 2015) 3
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3
  4. Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease. (PMID: 23144326) Kim D.K. … Silverman E.K. (Am. J. Respir. Crit. Care Med. 2012) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for RNF150 Gene

Sources for RNF150 Gene