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Aliases for RNF148 Gene

Aliases for RNF148 Gene

  • Ring Finger Protein 148 2 3 5

External Ids for RNF148 Gene

Previous GeneCards Identifiers for RNF148 Gene

  • GC07U901252
  • GC07M121896
  • GC07M121935
  • GC07M122128
  • GC07M122341
  • GC07M116705

Summaries for RNF148 Gene

GeneCards Summary for RNF148 Gene

RNF148 (Ring Finger Protein 148) is a Protein Coding gene. An important paralog of this gene is RNF167.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF148 Gene

Genomics for RNF148 Gene

Regulatory Elements for RNF148 Gene

Enhancers for RNF148 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around RNF148 on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF148 Gene

122,701,664 bp from pter
122,702,967 bp from pter
1,304 bases
Minus strand

Genomic View for RNF148 Gene

Genes around RNF148 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF148 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF148 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF148 Gene

Proteins for RNF148 Gene

  • Protein details for RNF148 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 148
    Protein Accession:
    Secondary Accessions:
    • A4D0X4
    • Q8N308

    Protein attributes for RNF148 Gene

    305 amino acids
    Molecular mass:
    34397 Da
    Quaternary structure:
    No Data Available

neXtProt entry for RNF148 Gene

Proteomics data for RNF148 Gene at MOPED

Post-translational modifications for RNF148 Gene

  • Glycosylation at Asn 43
  • Modification sites at PhosphoSitePlus

Other Protein References for RNF148 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF148 Gene

Domains & Families for RNF148 Gene

Gene Families for RNF148 Gene

Protein Domains for RNF148 Gene

Suggested Antigen Peptide Sequences for RNF148 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 PA (protease associated) domain.
  • Contains 1 RING-type zinc finger.
  • Contains 1 PA (protease associated) domain.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF148: view

Function for RNF148 Gene

genes like me logo Genes that share phenotypes with RNF148: view

Animal Model Products

  • Taconic Biosciences Mouse Models for RNF148

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF148 Gene

Localization for RNF148 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RNF148 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for RNF148 Gene COMPARTMENTS Subcellular localization image for RNF148 gene
Compartment Confidence
mitochondrion 2
cytosol 1
extracellular 1
lysosome 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for RNF148 Gene

Pathways & Interactions for RNF148 Gene

SuperPathways for RNF148 Gene

No Data Available

Interacting Proteins for RNF148 Gene

Gene Ontology (GO) - Biological Process for RNF148 Gene


No data available for Pathways by source and SIGNOR curated interactions for RNF148 Gene

Drugs & Compounds for RNF148 Gene

No Compound Related Data Available

Transcripts for RNF148 Gene

mRNA/cDNA for RNF148 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF148 Gene

Ring finger protein 148:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNF148 Gene

No ASD Table

Relevant External Links for RNF148 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF148 Gene

mRNA expression in normal human tissues for RNF148 Gene

mRNA differential expression in normal tissues according to GTEx for RNF148 Gene

This gene is overexpressed in Testis (x44.7).

SOURCE GeneReport for Unigene cluster for RNF148 Gene Hs.675191

mRNA Expression by UniProt/SwissProt for RNF148 Gene

Tissue specificity: Abundantly expressed in testis and slightly in pancreas. Mainly present in the interstitial cells of testicular tissues.
genes like me logo Genes that share expression patterns with RNF148: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for RNF148 Gene

Orthologs for RNF148 Gene

This gene was present in the common ancestor of animals.

Orthologs for RNF148 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia RNF148 35
  • 85.59 (n)
  • 82.18 (a)
(Canis familiaris)
Mammalia RNF148 35
  • 88.11 (n)
  • 86.67 (a)
(Mus musculus)
Mammalia Rnf148 35
  • 83.11 (n)
  • 82.12 (a)
Rnf148 16
Rnf148 36
  • 78 (a)
(Pan troglodytes)
Mammalia RNF148 35
  • 99.02 (n)
  • 97.38 (a)
(Rattus norvegicus)
Mammalia Rnf148 35
  • 83.89 (n)
  • 84.9 (a)
(Monodelphis domestica)
Mammalia RNF148 36
  • 70 (a)
(Gallus gallus)
Aves -- 36
  • 33 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 30 (a)
(Danio rerio)
Actinopterygii rnf128a 36
  • 34 (a)
si:dkeyp-86f7.4 36
  • 33 (a)
(Caenorhabditis elegans)
Secernentea H10E21.5 36
  • 14 (a)
Species with no ortholog for RNF148:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNF148 Gene

Gene Tree for RNF148 (if available)
Gene Tree for RNF148 (if available)

Paralogs for RNF148 Gene

(5) SIMAP similar genes for RNF148 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with RNF148: view

Variants for RNF148 Gene

Sequence variations from dbSNP and Humsavar for RNF148 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
VAR_028855 -

Variation tolerance for RNF148 Gene

Residual Variation Intolerance Score: 49.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.38; 27.28% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for RNF148 Gene

Disorders for RNF148 Gene

Relevant External Links for RNF148

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF148 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF148 Gene

Publications for RNF148 Gene

  1. Identification of a novel human testicular interstitial gene, RNF148, and its expression regulated by histone deacetylases. (PMID: 24089095) Liu Y.Q. … Zhang S.Z. (Genet. Mol. Res. 2013) 3 4 67
  2. Does this have a familiar RING? (PMID: 8744354) Saurin A.J. … Freemont P.S. (Trends Biochem. Sci. 1996) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3
  5. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3

Products for RNF148 Gene

Sources for RNF148 Gene