Aliases for RNF144A Gene
External Ids for RNF144A Gene
Previous HGNC Symbols for RNF144A Gene
Previous GeneCards Identifiers for RNF144A Gene
The protein encoded by this protein contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. The mouse counterpart of this protein has been shown to interact with Ube2l3/UbcM4, which is an ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Jul 2008]
GeneCards Summary for RNF144A Gene
RNF144A (Ring Finger Protein 144A) is a Protein Coding gene. Among its related pathways are Metabolism of proteins. GO annotations related to this gene include ligase activity. An important paralog of this gene is RNF144B.
UniProtKB/Swiss-Prot for RNF144A Gene
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the ubiquitination and degradation of the DNA damage kinase PRKDC.