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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

RNF13 Gene

protein-coding   GIFtS: 53
GCID: GC03P149531

Ring Finger Protein 13

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ring Finger Protein 131 2 3
RZF2 3
E3 Ubiquitin-Protein Ligase RNF132
RING Zinc Finger Protein2
EC 6.3.2.-3

External Ids:    HGNC: 100571   Entrez Gene: 113422   Ensembl: ENSG000000829967   OMIM: 6092475   UniProtKB: O435673   

Export aliases for RNF13 gene to outside databases

Previous GC identifers: GC03P146460 GC03P150415 GC03P150812 GC03P150851 GC03P151013 GC03P146902


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RNF13 Gene:
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein
interactions. The specific function of this gene has not yet been determined. Alternatively spliced transcript
variants that encode the same protein have been reported. A pseudogene, which is also located on chromosome 3,
has been defined for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for RNF13 Gene: 
RNF13 (ring finger protein 13) is a protein-coding gene. Diseases associated with RNF13 include prader-willi syndrome, and intrahepatic cholangiocarcinoma. GO annotations related to this gene include ubiquitin-protein ligase activity and zinc ion binding. An important paralog of this gene is ZNRF3.

UniProtKB/Swiss-Prot: RNF13_HUMAN, O43567
Function: E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation

Gene Wiki entry for RNF13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the RNF13 gene promoter:
         Nkx3-1   LHX3b/Lhx3b   Nkx3-1 v1   Nkx3-1 v2   POU2F1   POU2F1a   LHX3a/Lhx3a   Nkx3-1 v3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): RNF13 promoter sequence
   Search SABiosciences Chromatin IP Primers for RNF13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q25.1   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q25.1

RNF13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF13 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P149531:  view genomic region     (about GC identifiers)

Start:
149,530,475 bp from pter      End:
149,679,926 bp from pter
Size:
149,452 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: RNF13_HUMAN, O43567 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase RNF13 precursor  
Size: 381 amino acids; 42814 Da
Subcellular location: Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane;
Single-pass membrane protein (By similarity). Lysosome membrane. Nucleus inner membrane (By similarity).
Note=Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane (By
similarity)
Secondary accessions: Q6IBJ9

Explore the universe of human proteins at neXtProt for RNF13: NX_O43567

Explore proteomics data for RNF13 at MOPED 

Post-translational modifications:

  • UniProtKB: Auto-ubiquitinated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O43567

  • RNF13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    RNF13 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_009213.1  NP_899237.1  

    ENSEMBL proteins: 
     ENSP00000376628   ENSP00000341361   ENSP00000419836   ENSP00000419508   ENSP00000420667  
     ENSP00000418308   ENSP00000420124   ENSP00000419809   ENSP00000420067   ENSP00000419069  
     ENSP00000417655   ENSP00000420691   ENSP00000417294   ENSP00000355268   ENSP00000418863  
     ENSP00000420510  

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    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005637nuclear inner membrane IEA--
    GO:0005765lysosomal membrane ISS--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016021integral to membrane IEA--

    RNF13 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RNF: RING-type (C3HC4) zinc fingers

    3 InterPro protein domains:
     IPR003137 Protease-assoc_domain
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry O43567

    ProtoNet protein and cluster: O43567

    2 Blocks protein domains:
    IPB001841 Zn-finger
    IPB003137 Protease-associated PA


    UniProtKB/Swiss-Prot: RNF13_HUMAN, O43567
    Domain: The RING-type zinc finger domain is required for E3 ligase activity
    Similarity: Contains 1 PA (protease associated) domain
    Similarity: Contains 1 RING-type zinc finger


    RNF13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: RNF13_HUMAN, O43567
    Function: E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004842ubiquitin-protein ligase activity ISS--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    RNF13 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for RNF13:
     Increased cell death HMECs cel  Increased cell number in G2M,   Upregulation of NF-kappaB path 

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    SwitchGear 3'UTR luciferase reporter plasmidRNF13 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: RNF13_HUMAN, O43567
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for RNF13 (O435673 ENSP000003413614) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2D2P628373, ENSP000003817174I2D: score=2 STRING: ENSP00000381717
    UBE2D3P610773, ENSP000003497224I2D: score=2 STRING: ENSP00000349722
    UBE2NP610883, ENSP000003161764I2D: score=2 STRING: ENSP00000316176
    LAMP2P134733, ENSP000004084114I2D: score=1 STRING: ENSP00000408411
    CD63P089623, ENSP000002578574I2D: score=1 STRING: ENSP00000257857
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0051865protein autoubiquitination ISS--

    RNF13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    RNF13 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for RNF13

    1 Novoseek inferred chemical compound relationship for RNF13 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    zinc 30.6 2 11005251 (1), 12837286 (1)

    Search CenterWatch for drugs/clinical trials and news about RNF13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    About This Section

    REFSEQ mRNAs for RNF13 gene (5 alternative transcripts): 
    NM_007282.4  NM_183381.2  NM_183382.1  NM_183383.2  NM_183384.2  

    Unigene Cluster for RNF13:

    Ring finger protein 13
    Hs.12333  [show with all ESTs]
    Unigene Representative Sequence: NM_007282
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392894(uc003exp.4 uc010hvh.3) ENST00000344229(uc003exn.4)
    ENST00000470151 ENST00000466478 ENST00000491086 ENST00000467977 ENST00000474348
    ENST00000467996 ENST00000468648 ENST00000459632 ENST00000466795 ENST00000482539
    ENST00000490631 ENST00000361785 ENST00000482083 ENST00000468289 ENST00000493238

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    Inhib. RNA
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    Additional mRNA sequence: 

    AF037204.1 AF070558.1 AK090638.1 AK090771.1 AK313304.1 BC009781.1 BC009803.1 BC017878.1 
    CR456804.1 

    24/28 DOTS entries (see all 28):

    DT.441876  DT.91774635  DT.95247554  DT.100826598  DT.75173832  DT.40282609  DT.100640704  DT.100037136 
    DT.91976804  DT.100753634  DT.95247523  DT.91774632  DT.100826589  DT.92021369  DT.100037135  DT.112019 
    DT.120876256  DT.120876267  DT.120876272  DT.120876297  DT.120876316  DT.91658184  DT.91774633  DT.91774642 

    24/440 AceView cDNA sequences (see all 440):

    AL544548 BQ695102 AI375724 AF070558 NM_183381 AI373098 BQ575510 AI668881 
    NM_183382 AA975327 BC009803 AA846092 F10600 CB109037 CA844353 AI031720 
    CB153774 BM996553 AA341257 AI866066 BM976414 AV761990 AA962265 AI433737 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for RNF13    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                                                      
    SP2:              -     -           -                                                                     
    SP3:                    -     -     -                                                                     
    SP4:                                                                                                      


    ECgene alternative splicing isoforms for RNF13

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    RNF13 expression in normal human tissues (normalized intensities)      RNF13 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTCCACTT
    RNF13 Expression
    About this image


    RNF13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             monocytes   
     
     Inner Cell Mass (Early Embryonic Tissues)
             Inner Cell Mass Cells Inner Cell Mass

    See RNF13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for RNF13

    SOURCE GeneReport for Unigene cluster: Hs.12333

    UniProtKB/Swiss-Prot: RNF13_HUMAN, O43567
    Tissue specificity: Widely expressed (at protein level). In normal pancreas, expressed in islets, but not in
    ducts, nor in acini (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including RNF13: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for RNF13 gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnf131 , 5 ring finger protein 131, 5 89.59(n)1
    93.44(a)1
      3 (28.04 cM)5
    240171  NM_001113413.11  NP_001106884.11 
     577360665 
    chicken
    (Gallus gallus)
    Aves RNF131 ring finger protein 13 80.4(n)
    91.08(a)
      396303  NM_205355.1  NP_990686.1 
    lizard
    (Anolis carolinensis)
    Reptilia RNF136
    Uncharacterized protein
    89(a)
    1 ↔ 1
    3(18720332-18767362)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685562 hypothetical protein MGC68556 75.18(n)    BC063734.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc556602 similar to ring finger protein 13 76.48(n)   394019  BC044449.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG102771 , 3 CG102771 39(a)3
    45.78(n)1
    39.24(a)1
      83E53
    407911  NM_001104225.11  NP_001097695.11 
    worm
    (Caenorhabditis elegans)
    Secernentea C18B12.46
    Protein C18B12.4
    21(a)
    1 → many
    X(15036697-15040602)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G719801 protease-associated and C3HC4-type RING finger domain-containing more 46.72(n)
    35.91(a)
      843529  NM_105856.6  NP_177343.2 
    rice
    (Oryza sativa)
    Liliopsida Os03g01675001 hypothetical protein 50.39(n)
    38.76(a)
      4331745  NM_001055617.1  NP_001049082.1 


    ENSEMBL Gene Tree for RNF13 (if available)
    TreeFam Gene Tree for RNF13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for RNF13 gene
    ZNRF32  RNF432  RNF1482  RNF1492  RNF1332  RNF1502  RNF1302  RNF1672  
    RNF2152  RNF1282  ZNRF42  
    6 SIMAP similar genes for RNF13 using alignment to 16 protein entries:     RNF13_HUMAN (see all proteins):
    RNF167    ZNRF4    TRIM3    RNF130    RNF150    RNF24

    RNF13 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for RNF13
    PGOHUM00000237880


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2638 SNPs in RNF13 are shown (see all 2638)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1822191811,2
    --149528514(+) TAACCC/TTTCAT 2 -- us2k10--------
    rs1862454871,2
    --149528572(+) CTGCTG/TTAGAA 2 -- us2k10--------
    rs1914863101,2
    --149528613(+) TCCAAA/TTTACC 2 -- us2k10--------
    rs1387373961,2
    C--149528643(+) AGAGT-/AAATGT 2 -- us2k10--------
    rs126353721,2
    C,F,H--149528713(+) AGAACT/CATACC 2 -- us2k110Minor allele frequency- C:0.12NS EA NA 974
    rs730096271,2
    C,F--149528795(+) GCAAAG/ACTCTT 2 -- us2k12Minor allele frequency- A:0.11WA 120
    rs764146161,2
    C,F--149528859(+) CAAGAA/GGATCC 2 -- us2k13Minor allele frequency- G:0.05WA NA 240
    rs1460998311,2
    C--149529081(+) CTTGTC/GTCTAA 2 -- us2k10--------
    rs5447161,2
    C,F,H--149529187(+) TGCCCC/G/TAGTGC 2 -- us2k14NS EA 420
    rs98762101,2
    C,F,A,H--149529444(+) AAAAAT/ATTTAT 2 -- us2k17Minor allele frequency- A:0.39NS NA WA EA 576

    HapMap Linkage Disequilibrium report for RNF13 (149530475 - 149679926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for RNF13:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2676965CNV Deletion23128226
    esv2664861CNV Deletion23128226
    esv2597752CNV Deletion19546169
    esv993688CNV Insertion20482838
    esv1516102CNV Insertion17803354
    nsv877644CNV Loss21882294
    esv34142CNV Loss18971310
    nsv877643CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609247    OMIM disorders: --

    5 diseases for RNF13:    About MalaCards
    prader-willi syndrome    intrahepatic cholangiocarcinoma    cholangiocarcinoma    pancreatic cancer
    pancreatitis


    RNF13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): RNF13

    Export disorders for RNF13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for RNF13 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with RNF13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. RNF13: a novel RING-type ubiquitin ligase over-expressed in pancreatic cancer. (PubMed id 18794910)1, 2 Zhang Q....Zhu D. (2009)
    2. Integral and associated lysosomal membrane proteins. (PubMed id 17897319)1, 2 Schroeder B.... Hasilik A. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Nuclear targeting of an endosomal E3 ubiquitin ligase . (PubMed id 20230530)1, 9 Bocock J.P....Erickson A.H. (2010)
    6. E3 ubiquitin ligase RNF13 involves spatial learning an d assembly of the SNARE complex. (PubMed id 22890573)1 Zhang Q....Zhu D. (2013)
    7. RNF13, a RING finger protein, mediates endoplasmic ret iculum stress-induced apoptosis through the inositol-requiring enzyme (IRE1a)/c- Jun NH2-terminal kinase pathway. (PubMed id 23378536)1 Arshad M....Li P. (2013)
    8. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11342 HGNC: 10057 AceView: RNF13 Ensembl:ENSG00000082996 euGenes: HUgn11342
    ECgene: RNF13 H-InvDB: RNF13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for RNF13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for RNF13 gene:
    Search GeneIP for patents involving RNF13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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