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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

RNF125 Gene

protein-coding GIFtS: 54
GCID: GC18P029598

ring finger protein 125, E3 ubiquitin protein ligase

(Previous name: ring finger protein 125 )

Explore 2 diseases affiliated with
RNF125 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ring Finger Protein 125, E3 Ubiquitin Protein Ligase¹ ²		TRAC1²
RING Finger Protein 125¹ ³		E3 Ubiquitin-Protein Ligase RNF125²
TRAC-1² ³		T-Cell Ring Protein Identified In Activation Screen²
T-Cell RING Activation Protein 1² ³		EC 6.3.2.-³
FLJ20456¹

External Ids:	HGNC: 21150¹	Entrez Gene: 54941²	Ensembl: ENSG00000101695⁷	OMIM: 610432⁵	UniProtKB: Q96EQ8³

Export aliases for RNF125 gene to outside databases

Previous GC identifers: GC18P029486 GC18P027850 GC18P027852 GC18P026455

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for RNF125:

This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three

zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein

associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may

function as a positive regulator in the T-cell receptor signaling pathway. (provided by RefSeq, Mar 2012)

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8

Function: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins

mediate ubiquitination and subsequent proteasomal degradation of target proteins

Gene Wiki entry for RNF125

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000018.9 NC_018929.1 NT_010966.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the RNF125 gene promoter:
USF1 USF-1:USF-2 RelA NF-kappaB SRY USF-1 IRF-7A ZIC2/Zic2 NF-kappaB1 Zic3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: RNF125 promoter sequence

Search SABiosciences Chromatin IP Primers for RNF125

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF125

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q12.1 Ensembl cytogenetic band: 18q12.1 HGNC cytogenetic band: 18q12.1

RNF125 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF125 gene location

GeneLoc information about chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18P029598: view genomic region (about GC identifiers)

Start:	29,598,335 bp from pter	End:	29,653,176 bp from pter
Size:	54,842 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8 (See protein sequence)

Recommended Name: E3 ubiquitin-protein ligase RNF125

Size: 232 amino acids; 26454 Da

Secondary accessions: Q9NX39

Explore the universe of human proteins at neXtProt for RNF125: NX_Q96EQ8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96EQ8

RNF125 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_060301.2

ENSEMBL proteins:

ENSP00000217740 ENSP00000463935

Reactome Protein details: Q96EQ8
Human Recombinant Protein Products:

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	Uscn Proteins for RNF125

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	IEA	--

RNF125 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

RNF125 for domains About GeneDecksing

4 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR017907 Znf_RING_CS

IPR001841 Znf_RING

IPR013083 Znf_RING/FYVE/PHD

Graphical View of Domain Structure for InterPro Entry Q96EQ8

ProtoNet protein and cluster: Q96EQ8

1 Blocks protein family: IPB001841 Zn-finger

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8

Similarity: Contains 1 RING-type zinc finger

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8

Function: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins

mediate ubiquitination and subsequent proteasomal degradation of target proteins

Enzyme Number (IUBMB): EC 6.3.2.-¹

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		hsa-miR-142-5p hsa-miR-219-1-3p hsa-miR-642a hsa-miR-4328 hsa-miR-15a hsa-miR-938 hsa-miR-16-1* hsa-miR-3653

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF125

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004842	ubiquitin-protein ligase activity	IEA	--
GO:0008270	zinc ion binding	IEA	--

RNF125 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways

	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	1.00			Negative regulators of RIG-I/MDA5 signaling	0.49
	RIG-I-like receptor signaling pathway	0.52

Immune System

Immune System

1.00

Innate Immune System

0.46

RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1

RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1

0.88

Pathway sources
See GeneCards unified pathways
Show all pathways

5 Reactome Pathways for RNF125

	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
	Negative regulators of RIG-I/MDA5 signaling
	RNF125 mediated ubiquitination of RIG-I, MDA5 and IPS-1
	Immune System
	Innate Immune System

1 Kegg Pathway (Kegg details for RNF125):

RIG-I-like receptor signaling pathway

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8

Pathway: Protein modification; protein ubiquitination

RNF125 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for RNF125

STRING Interaction Network Preview (showing 5 interactants - click image to see 18)

5/20 Interacting proteins for RNF125 (Q96EQ8³ ENSP00000217740⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 20)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBE2L6	O14933³, ENSP00000287156⁴	I2D: score=3 STRING: ENSP00000287156
UBE2D2	P62837³, ENSP00000381717⁴	I2D: score=2 STRING: ENSP00000381717
UBE2D3	P61077³, ENSP00000349722⁴	I2D: score=2 STRING: ENSP00000349722
UBE2N	P61088³, ENSP00000316176⁴	I2D: score=2 STRING: ENSP00000316176
UBE2U	Q5VVX9³, ENSP00000360116⁴	I2D: score=2 STRING: ENSP00000360116

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016567	protein ubiquitination	--	--
GO:0032480	negative regulation of type I interferon production	TAS	--
GO:0045087	innate immune response	TAS	--

RNF125 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for RNF125
Search CenterWatch for drugs/clinical trials and news about RNF125 / RN125

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for RNF125 gene:

NM_017831.3

Unigene Cluster for RNF125:

Ring finger protein 125, E3 ubiquitin protein ligase

Hs.633703 [show with all ESTs]

Unigene Representative Sequence: NM_017831

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000217740(uc002kxf.1) ENST00000580209 ENST00000583384 ENST00000583814

ENST00000580863

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat RNF125
		8/58 QIAGEN miScript miRNA Assays for microRNAs that regulate RNF125 (see all 58):
		hsa-miR-142-5p hsa-miR-219-1-3p hsa-miR-642a hsa-miR-4328 hsa-miR-15a hsa-miR-938 hsa-miR-16-1* hsa-miR-3653

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF125

Additional cDNA sequence:

AK000463.1 AK027134.1 AK225518.1 BC012021.1

3 DOTS entries:

DT.91795393 DT.91688233 DT.91659035

17 AceView cDNA sequences:

NM_017831 BE302781 BX283264 BG387827 BC012021 BU500546 BQ225812 BI666910

BE384400 AK000463 AV760621 AL713489 BM469263 BQ879004 AV762059 BV185326

CD684818

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for RNF125 About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3a	·	3b	^	4	^	5a	·	5b	^	6a	·	6b
SP1:									-								-
SP2:									-								-
SP3:									-		-
SP4:															-		-

ECgene alternative splicing isoforms for RNF125

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

RNF125 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATTCTTCT

About this image

RNF125 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Antral Follicle

Cumulus Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

See RNF125 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for RNF125

SOURCE GeneReport for Unigene cluster: Hs.633703

UniProtKB/Swiss-Prot: RN125_HUMAN, Q96EQ8

Tissue specificity: Predominantly expressed in lymphoid tissues, including bone marrow, spleen and thymus. Also weakly

expressed in other tissues. Predominant in the CD4+ and CD8+ T-cells, suggesting that it is preferentially confined to

T-cells

SABiosciences Expression via Pathway-Focused PCR Array including RNF125:

Ubiquitin Ligases in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for RNF125 gene from 2/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	RNF125⁶	--	63(a)	1 ↔ 1	GL343207.1(3443845-3451870)
zebrafish (Danio rerio)	Actinopterygii	CT583652.1⁶	--	13(a)	1 ↔ 1	20(6582578-6595777)

ENSEMBL Gene Tree for RNF125 (if available)
TreeFam Gene Tree for RNF125 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for RNF125 gene

RNF166² RNF138² RNF114²

1 SIMAP similar gene for RNF125 using alignment to 2 protein entries: RN125_HUMAN (see all proteins):

RNF114

RNF125 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 18 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs193288346^1,2		--	29596509(+)	`GAAGCA/GGATAT`	1	--	us2k¹		0	--	--	--	--
rs183834218^1,2		--	29596607(+)	`CCCCCC/GCCCCA`	1	--	us2k¹		0	--	--	--	--
rs74171363^1,2	C,	--	29596609(-)	`GGTGGTGG/-GGGGG`	1	--	us2k¹		1		NA	2
rs148748658^1,2		--	29596901(+)	`TTGTTA/GTTTGT`	1	--	us2k¹		0	--	--	--	--
rs117822943^1,2		--	29596923(+)	`AGTCTC/TGCTCT`	1	--	us2k¹		1		NA	120
rs4799322^1,2	C,F,A,H,	--	29596992(+)	`GGTGCA/GAGTGG`	1	--	us2k¹		8		EA NS NA WA CSA	272
rs4799323^1,2	C,F,A,	--	29597035(+)	`CTACAA/CGCATG`	1	--	us2k¹		3		NA WA CSA	6
rs140124515^1,2		--	29597115(+)	`AGAGAC/TGGGGT`	1	--	us2k¹		0	--	--	--	--
rs145548984^1,2		--	29597129(+)	`ACTATA/GTTGGC`	1	--	us2k¹		0	--	--	--	--
rs4799623^1,2	C,F,	--	29597300(+)	`ACTGCC/AGCCTC`	1	--	us2k¹		4		NA WA CSA	8

HapMap Linkage Disequilibrium report for RNF125 (29598335 - 29653176 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for RNF125
1 CNV: 3163

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF125

DNA2.0 Custom Variant and Variant Library Synthesis for RNF125

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

RNF125 for disorders           About GeneDecksing

OMIM gene information: 610432    OMIM disorders: --

2 diseases for RNF125:    About MalaCards

colorectal cancer psoriasis

Export disorders for RNF125 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for RNF125 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with RNF125)

Utopia: connect your pdf to the dynamic
world of online information

A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation. (PubMed id 15843525)^{1, 2} Zhao H.... Masuda E.S. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Systematic identification of regulatory proteins critical for T-cell activation. (PubMed id 12974981)^{1, 2} Chu P.... Liao X.C. (2003)
T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain. (PubMed id 17990982)^{1, 9} Giannini A.L....Bijlmakers M.J. (2008)
Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)¹ Woodsmith J....Sanderson C.M. (2012)
The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)¹ Lin C.W....Jan M.S. (2012)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Functional analysis of the RNF114 psoriasis susceptib ility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis. (PubMed id 21571784)¹ Bijlmakers M.J....Capon F. (2011)
Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)¹ Markson G....Sanderson C.M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 54941	HGNC: 21150	AceView: RNF125	Ensembl:ENSG00000101695	euGenes: HUgn54941
ECgene: RNF125	Kegg: 54941	H-InvDB: RNF125

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for RNF125	Pharmacogenomics, SNPs, Pathways

Intellectual Property for RNF125 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for RNF125 gene:
Search GeneIP for patents involving RNF125

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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RNF125 Gene

ring finger protein 125, E3 ubiquitin protein ligase

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RNF125 Gene

ring finger protein 125, E3 ubiquitin protein ligase

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