Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



RNF121 Gene

protein-coding   GIFtS: 45
GCID: GC11P071640

Ring Finger Protein 121

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Ring Finger Protein 1211 2

External Ids:    HGNC: 210701   Entrez Gene: 552982   Ensembl: ENSG000001375227   UniProtKB: Q9H9203   

Export aliases for RNF121 gene to outside databases

Previous GC identifers: GC11P071862 GC11P071366 GC11P071317 GC11P067933


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for RNF121 Gene:
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct
proteins and known to be involved in protein-protein and protein-DNA interactions. Several alternatively spliced
transcript variants have been noted for this gene, however, not all are likely to encode viable protein products.
(provided by RefSeq, Sep 2008)

GeneCards Summary for RNF121 Gene:
RNF121 (ring finger protein 121) is a protein-coding gene. An important paralog of this gene is RNF175.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the RNF121 gene promoter:
         ISGF-3   AML1a   E4BP4   FOXL1   IRF-2   CP2   COMP1   c-Myb   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidRNF121 promoter sequence
   Search Chromatin IP Primers for RNF121

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RNF121


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.4   Ensembl cytogenetic band:  11q13.4   HGNC cytogenetic band: 11q13.3

RNF121 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
RNF121 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P071640:  view genomic region     (about GC identifiers)

Start:
71,639,747 bp from pter      End:
71,708,643 bp from pter
Size:
68,897 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for RNF121

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: RN121_HUMAN, Q9H920 (See protein sequence)
Recommended Name: RING finger protein 121  
Size: 327 amino acids; 37882 Da
Sequence caution: Sequence=AAH09672.2; Type=Erroneous initiation; Sequence=AAH63680.1; Type=Erroneous initiation;
Secondary accessions: Q6IA57 Q6P449 Q96DB4

Explore the universe of human proteins at neXtProt for RNF121: NX_Q9H920

Explore proteomics data for RNF121 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See RNF121 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060790.2  
    ENSEMBL proteins: 
     ENSP00000354571   ENSP00000431325   ENSP00000377314   ENSP00000432898   ENSP00000433574  
     ENSP00000377316   ENSP00000434127   ENSP00000435859   ENSP00000431286   ENSP00000443799  

    RNF121 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for RNF121
    OriGene Custom MassSpec
    OriGene Custom Protein Services for RNF121
    GenScript Custom Purified and Recombinant Proteins Services for RNF121
    Novus Biologicals RNF121 Protein
    Novus Biologicals RNF121 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for RNF121

     
    Search eBioscience for Proteins for RNF121 

    RNF121 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for RNF121
    Novus Biologicals RNF121 Antibodies
    Abcam antibodies for RNF121
    Cloud-Clone Corp. Antibodies for RNF121
    Search ThermoFisher Antibodies for RNF121
    LSBio Antibodies in human, mouse, rat for RNF121

    RNF121 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for RNF121
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for RNF121
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for RNF121
    Cloud-Clone Corp. CLIAs for RNF121
    Search eBioscience for ELISAs for RNF121 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    RNF: RING-type (C3HC4) zinc fingers

    2 InterPro protein domains:
     IPR001841 Znf_RING
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9H920

    ProtoNet protein and cluster: Q9H920

    1 Blocks protein domain: IPB001841 Zn-finger

    UniProtKB/Swiss-Prot: RN121_HUMAN, Q9H920
    Similarity: Belongs to the RNF121 family
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with RNF121           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with RNF121           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RNF121
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RNF121

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for RNF121
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for RNF121

    miRNA
    Products:
        
    miRTarBase miRNAs that target RNF121:
    hsa-mir-335-5p (MIRT017093), hsa-mir-92a-3p (MIRT049659)

    Block miRNA regulation of human, mouse, rat RNF121 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNF121 (see all 30):
    hsa-miR-4286 hsa-miR-892b hsa-miR-136 hsa-miR-146b-3p hsa-miR-125a-5p hsa-miR-3660 hsa-miR-1224-3p hsa-miR-1260b
    SwitchGear 3'UTR luciferase reporter plasmidRNF121 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for RNF121
    Predesigned siRNA for gene silencing in human, mouse, rat RNF121

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for RNF121

    Clone
    Products:
         
    OriGene clones in human, mouse for RNF121 (see all 11)
    OriGene ORF clones in mouse, rat for RNF121
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RNF121 (NM_018320)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF121
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF121

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for RNF121
    Browse ESI BIO Cell Lines and PureStem Progenitors for RNF121 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF121


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    RN121_HUMAN, Q9H920: Membrane; Multi-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    peroxisome2
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with RNF121           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Array including RNF121: 
              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for RNF121

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for RNF121 (ENSP000003545714) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ITGB1ENSP000003640944STRING: ENSP00000364094
    ITGB5ENSP000002961814STRING: ENSP00000296181
    ITGB6ENSP000002832494STRING: ENSP00000283249
    --ENSP000002620174STRING: ENSP00000262017
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for RNF121 (RN121)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for RNF121 gene (3 alternative transcripts): 
    NM_018320.4  NM_194452.1  NM_194453.1  

    Unigene Cluster for RNF121:

    Ring finger protein 121
    Hs.368554  [show with all ESTs]
    Unigene Representative Sequence: NR_024148
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361756(uc001ord.3 uc001ora.3 uc001orb.3 uc009yst.3)
    ENST00000530058 ENST00000393711 ENST00000530655 ENST00000533380 ENST00000393713
    ENST00000490867 ENST00000528683 ENST00000526549 ENST00000525243 ENST00000530137
    ENST00000526903 ENST00000525176 ENST00000532379 ENST00000545854
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat RNF121 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate RNF121 (see all 30):
    hsa-miR-4286 hsa-miR-892b hsa-miR-136 hsa-miR-146b-3p hsa-miR-125a-5p hsa-miR-3660 hsa-miR-1224-3p hsa-miR-1260b
    SwitchGear 3'UTR luciferase reporter plasmidRNF121 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for RNF121
    Predesigned siRNA for gene silencing in human, mouse, rat RNF121
    Clone
    Products:
         
    OriGene clones in human, mouse for RNF121 (see all 11)
    OriGene ORF clones in mouse, rat for RNF121
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: RNF121 (NM_018320)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for RNF121
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF121
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for RNF121
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RNF121
      QuantiTect SYBR Green Assays in human, mouse, rat RNF121
      QuantiFast Probe-based Assays in human, mouse, rat RNF121

    Additional mRNA sequence: 

    AK001961.1 AK023139.1 AK094508.1 AL833638.1 BC009672.2 BC063680.1 BC093084.1 BC117273.1 
    CR457298.1 NR_024147.1 NR_024148.1 

    11 DOTS entries:

    DT.100814850  DT.101982502  DT.120683668  DT.70100736  DT.100024016  DT.120683629  DT.91995046  DT.95373403 
    DT.100701778  DT.120683578  DT.75121316 

    Selected AceView cDNA sequences (see all 111):

    BF904376 CD516294 NM_018320 NM_194453 NM_194452 CR625242 AI963986 BM562917 
    BI916895 AL548102 AI038812 BG682750 AL541224 AU131066 AL561161 CA396524 
    BX463021 BQ773387 CA433848 BX372861 CA446331 CR457298 BF680305 BG122855 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    RNF121 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCTGGGTTG
    RNF121 Expression
    About this image

    RNF121 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    RNF121 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.368554
        Pathway & Disease-focused RT2 Profiler PCR Array including RNF121: 
              Ubiquitin Ligases in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for RNF121
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RNF121
    QuantiTect SYBR Green Assays in human, mouse, rat RNF121
    QuantiFast Probe-based Assays in human, mouse, rat RNF121
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF121

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for RNF121 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Rnf1211 , 5 ring finger protein 1211, 5 91.54(n)1
    98.17(a)1
      7 (54.71 cM)5
    752121  NM_029211.21  NP_083487.21 
     1020191375 
    chicken
    (Gallus gallus)
    Aves RNF1211 ring finger protein 121 84.51(n)
    94.46(a)
      419092  XM_417284.4  XP_417284.2 
    lizard
    (Anolis carolinensis)
    Reptilia RNF1216
    ring finger protein 121
    83(a)
    1 ↔ 1
    AAWZ02041618(201-344)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC691292 hypothetical protein MGC69129 81.75(n)    BC057753.1 
    zebrafish
    (Danio rerio)
    Actinopterygii rnf1211 ring finger protein 121 73.6(n)
    80.12(a)
      606559  XM_002666086.2  XP_002666132.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG158141 CG15814 64.7(n)
    60(a)
      32765  NM_167577.2  NP_728098.1 
    worm
    (Caenorhabditis elegans)
    Secernentea rnf-1211 rnf-121 57.11(n)
    54.33(a)
      182681  NM_065431.4  NP_497832.1 


    ENSEMBL Gene Tree for RNF121 (if available)
    TreeFam Gene Tree for RNF121 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for RNF121 gene
    RNF1752  
    3 SIMAP similar genes for RNF121 using alignment to 11 protein entries:     RN121_HUMAN (see all proteins):
    L3MBTL2    RNF175    ETFA

    Find genes that share paralogs with RNF121           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for RNF121 (see all 1243)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1838158461,2
    --71641525(+) AAATTA/GACAGG 3 -- int10--------
    rs1131717941,2
    C,F--71641536(+) TGATCA/GCAGCA 3 -- int12Minor allele frequency- G:0.11CSA WA 119
    rs556692261,2
    C--71641589(+) CACTA-/GAGACT 3 -- int11Minor allele frequency- G:0.00NA 2
    rs797336201,2
    C--71641599(+) TACAGG/ATGTTT 3 -- int11Minor allele frequency- A:0.50CSA 2
    rs752083621,2
    C,F--71641655(+) CCAAGA/TCCCCT 3 -- int11Minor allele frequency- T:0.08WA 118
    rs1890240171,2
    --71641688(+) TTACAA/GTTGGC 3 -- int10--------
    rs1464365791,2
    C--71641743(+) ATACTA/GTATTG 3 -- int10--------
    rs783026421,2
    F--71641800(+) ATTACG/CTATAT 3 -- int11Minor allele frequency- C:0.01EA 120
    rs1407860531,2
    --71641850(+) AAACAC/GCAGAA 3 -- int10--------
    rs1816627191,2
    --71641946(+) CAATCC/TCAGCT 3 -- int10--------

    HapMap Linkage Disequilibrium report for RNF121 (71639747 - 71708643 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for RNF121:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509428CNV Insertion20534489
    esv32752CNV Loss17666407
    nsv428262CNV Gain+Loss18775914
    dgv396e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing RNF121
    DNA2.0 Custom Variant and Variant Library Synthesis for RNF121

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with RNF121           About GenesLikeMe

    Genetic Association Database (GAD): RNF121

    Export disorders for RNF121 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for RNF121 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with RNF121)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    4. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (Nat. Biotechnol. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 55298 HGNC: 21070 AceView: RNF121 Ensembl:ENSG00000137522 euGenes: HUgn55298
    ECgene: RNF121 H-InvDB: RNF121

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for RNF121 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for RNF121 gene:
    Search GeneIP for patents involving RNF121

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for RNF121  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for RNF121  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for RNF121  
     OriGene qSTAR qPCR primer pairs in human, mouse for RNF121   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for RNF121   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for RNF121   OriGene Custom Protein Services for RNF121  

     
     
     Block miRNA regulation of human, mouse, rat RNF121 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing RNF121
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat RNF121 Predesigned siRNA for gene silencing in human, mouse, rat RNF121
     QuantiFast Probe-based Assays in human, mouse, rat RNF121 QuantiTect SYBR Green Assays in human, mouse, rat RNF121
     PCR Arrays including human, mouse, rat RNF121 Search Chromatin IP Primers for RNF121
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat RNF121  Search GeneGlobe Interaction Network for RNF121
     Regulatory tfbs in RNF121 promoter
     GenScript Custom Purified and Recombinant Proteins Services for RNF121 GenScript cDNA clones with any tag delivered in your preferred vector for RNF121
     GenScript Custom Assay Services for RNF121 GenScript Custom overexpressing Cell Line Services for RNF121
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for RNF121 (RN121)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     RNF121 antibodies
     RNF121 proteins
     RNF121 lysates
     Antibodies for RNF121
     See all of Abcam's Antibodies, Kits and Proteins for RNF121
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for RNF121
     Antibodies for RNF121
     ELISAs for RNF121
     CLIAs for RNF121



     Browse ESI BIO Cell Lines and PureStem Progenitors for RNF121
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF121
     SwitchGear 3'UTR luciferase reporter plasmids for RNF121
     SwitchGear Promoter luciferase reporter plasmids for RNF121
     Search ThermoFisher Antibodies for RNF121
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF121
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for RNF121
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for RNF121
     LSBio Antibodies in human, mouse, rat for RNF121
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for RNF121
      Search eBioscience for proteins for RNF121
      Search eBioscience for elisas for RNF121
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      RNF121 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4