Aliases for RNF114 Gene
External Ids for RNF114 Gene
Previous Symbols for RNF114 Gene
GeneCards Summary for RNF114 Gene
RNF114 (Ring Finger Protein 114) is a Protein Coding gene. An important paralog of this gene is RNF166.
UniProtKB/Swiss-Prot for RNF114 Gene
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycles G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.