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Aliases for RNF113B Gene

Aliases for RNF113B Gene

  • Ring Finger Protein 113B 2 3 5
  • Zinc Finger Protein 183-Like 1 2 3 4
  • ZNF183L1 3 4
  • RNF161 3 4
  • BA10G5.1 3

External Ids for RNF113B Gene

Previous HGNC Symbols for RNF113B Gene

  • ZNF183L1

Previous GeneCards Identifiers for RNF113B Gene

  • GC00U921548
  • GC13M097627
  • GC13M098828
  • GC13M079425

Summaries for RNF113B Gene

GeneCards Summary for RNF113B Gene

RNF113B (Ring Finger Protein 113B) is a Protein Coding gene. An important paralog of this gene is RNF113A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF113B Gene

Genomics for RNF113B Gene

Regulatory Elements for RNF113B Gene

Enhancers for RNF113B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13F098170 1.5 FANTOM5 Ensembl ENCODE 14.1 +3.4 3419 5.9 PKNOX1 MLX ARID4B FEZF1 ZNF48 ZNF2 YY1 GLIS2 FOS SP5 RNF113B FARP1 GC13M098177 PIR42956 LOC105370328
GH13F098141 1.3 Ensembl ENCODE 11.3 +32.4 32435 5.8 SIN3A ARID4B DMAP1 ZNF48 ZNF2 YY1 SLC30A9 GLIS2 ZNF202 NCOA1 RNF113B STK24-AS1 LOC105370328 GC13M098177 PIR42956
GH13F098201 1.1 Ensembl ENCODE 11.5 -25.1 -25072 1.1 RAD21 RARA YY1 CBX5 ZNF143 CREM TBX21 NR2F2 SMARCA4 ETV4 RNF113B RN7SKP8
GH13F098198 1.1 Ensembl ENCODE 11.5 -22.8 -22837 2.9 SOX13 SAP130 TEAD4 CEBPG ZNF644 RARA TEAD3 CBX5 NR2F6 GATAD2A RNF113B FARP1 RN7SKP8
GH13F098203 0.4 ENCODE 11.5 -26.5 -26535 0.2 ZBTB40 RNF113B FARP1 RN7SKP8
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around RNF113B on UCSC Golden Path with GeneCards custom track

Genomic Location for RNF113B Gene

98,175,785 bp from pter
98,177,267 bp from pter
1,483 bases
Minus strand

Genomic View for RNF113B Gene

Genes around RNF113B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RNF113B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RNF113B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF113B Gene

Proteins for RNF113B Gene

  • Protein details for RNF113B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RING finger protein 113B
    Protein Accession:
    Secondary Accessions:
    • Q8WWF9
    • Q96QY9

    Protein attributes for RNF113B Gene

    322 amino acids
    Molecular mass:
    36259 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RNF113B Gene

neXtProt entry for RNF113B Gene

Post-translational modifications for RNF113B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RNF113B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF113B Gene

Domains & Families for RNF113B Gene

Gene Families for RNF113B Gene

Suggested Antigen Peptide Sequences for RNF113B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C3H1-type zinc finger.
  • Contains 1 C3H1-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with RNF113B: view

Function for RNF113B Gene

Gene Ontology (GO) - Molecular Function for RNF113B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with RNF113B: view
genes like me logo Genes that share phenotypes with RNF113B: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for RNF113B Gene

Localization for RNF113B Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RNF113B gene
Compartment Confidence
nucleus 5
cytosol 2

Gene Ontology (GO) - Cellular Components for RNF113B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005684 U2-type spliceosomal complex IBA --
genes like me logo Genes that share ontologies with RNF113B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for RNF113B Gene

Pathways & Interactions for RNF113B Gene

SuperPathways for RNF113B Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF113B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034247 snoRNA splicing IBA --
GO:0045292 mRNA cis splicing, via spliceosome IBA --
genes like me logo Genes that share ontologies with RNF113B: view

No data available for Pathways by source and SIGNOR curated interactions for RNF113B Gene

Transcripts for RNF113B Gene

mRNA/cDNA for RNF113B Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(19) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF113B Gene

Ring finger protein 113B:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for RNF113B Gene

No ASD Table

Relevant External Links for RNF113B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RNF113B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RNF113B Gene

mRNA differential expression in normal tissues according to GTEx for RNF113B Gene

This gene is overexpressed in Testis (x51.0).

Protein differential expression in normal tissues from HIPED for RNF113B Gene

This gene is overexpressed in Heart (39.0) and Testis (27.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RNF113B Gene

Protein tissue co-expression partners for RNF113B Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RNF113B Gene:


SOURCE GeneReport for Unigene cluster for RNF113B Gene:

genes like me logo Genes that share expression patterns with RNF113B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RNF113B Gene

Orthologs for RNF113B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RNF113B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RNF113B 34 35
  • 99.48 (n)
(Mus musculus)
Mammalia Rnf113a2 35
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 60 (a)
(Gallus gallus)
Aves RNF113A 35
  • 59 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 59 (a)
(Danio rerio)
Actinopterygii rnf113a 35
  • 57 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4973 35
  • 42 (a)
(Caenorhabditis elegans)
Secernentea rnf-113 35
  • 33 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CWC24 35
  • 29 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU01954 34
  • 50 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 46 (a)
Species where no ortholog for RNF113B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNF113B Gene

Gene Tree for RNF113B (if available)
Gene Tree for RNF113B (if available)

Paralogs for RNF113B Gene

Paralogs for RNF113B Gene

(2) SIMAP similar genes for RNF113B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RNF113B: view

Variants for RNF113B Gene

Sequence variations from dbSNP and Humsavar for RNF113B Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs111427949 -- 98,177,888(+) AGCAA(C/T)ACACG intron-variant, upstream-variant-2KB
rs111520418 -- 98,177,101(+) GCTGC(A/G/T)CTCTC intron-variant, reference, missense
rs113354899 -- 98,175,952(+) TCCAT(C/T)CATCC intron-variant, utr-variant-3-prime
rs113453013 -- 98,179,202(+) CTCGC(A/G)TGGCA intron-variant, upstream-variant-2KB
rs113665583 -- 98,177,214(+) TCCTT(C/G)CTGGA intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for RNF113B Gene

Variant ID Type Subtype PubMed ID
nsv1045047 CNV gain 25217958
nsv7246 OTHER inversion 18451855

Variation tolerance for RNF113B Gene

Residual Variation Intolerance Score: 72.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.06; 50.57% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for RNF113B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNF113B Gene

Disorders for RNF113B Gene

Relevant External Links for RNF113B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for RNF113B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RNF113B Gene

Publications for RNF113B Gene

  1. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3 64
  4. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein J.I. … Sullivan P.F. (Nat Commun 2014) 3 64
  5. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PMID: 19549727) Markson G. … Sanderson C.M. (Genome Res. 2009) 3 64

Products for RNF113B Gene

Sources for RNF113B Gene

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