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Aliases for RNF113B Gene

Aliases for RNF113B Gene

  • Ring Finger Protein 113B 2 3
  • Zinc Finger Protein 183-Like 1 2 3 4
  • ZNF183L1 3 4
  • RNF161 3 4
  • BA10G5.1 3

External Ids for RNF113B Gene

Previous Symbols for RNF113B Gene

  • ZNF183L1

Summaries for RNF113B Gene

GeneCards Summary for RNF113B Gene

RNF113B (Ring Finger Protein 113B) is a Protein Coding gene. An important paralog of this gene is RNF113A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RNF113B Gene

Genomics for RNF113B Gene

Genomic Location for RNF113B Gene

Start:
98,175,785 bp from pter
End:
98,177,267 bp from pter
Size:
1,483 bases
Orientation:
Minus strand

Genomic View for RNF113B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for RNF113B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RNF113B Gene

Regulatory Elements for RNF113B Gene

Proteins for RNF113B Gene

  • Protein details for RNF113B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IZP6-R113B_HUMAN
    Recommended name:
    RING finger protein 113B
    Protein Accession:
    Q8IZP6
    Secondary Accessions:
    • Q8WWF9
    • Q96QY9

    Protein attributes for RNF113B Gene

    Size:
    322 amino acids
    Molecular mass:
    36259 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for RNF113B Gene

neXtProt entry for RNF113B Gene

Proteomics data for RNF113B Gene at MOPED

Post-translational modifications for RNF113B Gene

No Post-translational modifications

Other Protein References for RNF113B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RNF113B Gene

Domains for RNF113B Gene

Gene Families for RNF113B Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers

Protein Domains for RNF113B Gene

Suggested Antigen Peptide Sequences for RNF113B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8IZP6

UniProtKB/Swiss-Prot:

R113B_HUMAN
Similarity:
  • Contains 1 C3H1-type zinc finger.:
    • Q8IZP6
  • Contains 1 RING-type zinc finger.:
    • Q8IZP6
genes like me logo Genes that share domains with RNF113B: view

Function for RNF113B Gene

Gene Ontology (GO) - Molecular Function for RNF113B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding --
genes like me logo Genes that share ontologies with RNF113B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for RNF113B Gene

Localization for RNF113B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for RNF113B Gene COMPARTMENTS Subcellular localization image for RNF113B gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RNF113B Gene

Pathways for RNF113B Gene

SuperPathways for RNF113B Gene

No Data Available

Gene Ontology (GO) - Biological Process for RNF113B Gene

None

No data available for Pathways by source for RNF113B Gene

Transcripts for RNF113B Gene

mRNA/cDNA for RNF113B Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(19) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for RNF113B Gene

Ring finger protein 113B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for RNF113B Gene

No ASD Table

Relevant External Links for RNF113B Gene

GeneLoc Exon Structure for
RNF113B
ECgene alternative splicing isoforms for
RNF113B

Expression for RNF113B Gene

mRNA expression in normal human tissues for RNF113B Gene

mRNA differential expression in normal tissues according to GTEx for RNF113B Gene

This gene is overexpressed in Testis (51.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for RNF113B Gene

SOURCE GeneReport for Unigene cluster for RNF113B Gene Hs.296045

genes like me logo Genes that share expressions with RNF113B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for RNF113B Gene

Orthologs for RNF113B Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for RNF113B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia RNF113B 35
  • 99.48 (n)
  • 99.07 (a)
RNF113B 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Rnf113a2 36
  • 66 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 60 (a)
OneToMany
chicken
(Gallus gallus)
Aves RNF113A 36
  • 59 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 59 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii rnf113a 36
  • 57 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4973 36
  • 42 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea rnf-113 36
  • 33 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CWC24 36
  • 29 (a)
OneToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU01954 35
  • 50 (n)
  • 41.12 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 46 (a)
OneToMany
Species with no ortholog for RNF113B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for RNF113B Gene

ENSEMBL:
Gene Tree for RNF113B (if available)
TreeFam:
Gene Tree for RNF113B (if available)

Paralogs for RNF113B Gene

Paralogs for RNF113B Gene

Selected SIMAP similar genes for RNF113B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with RNF113B: view

Variants for RNF113B Gene

Sequence variations from dbSNP and Humsavar for RNF113B Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
VAR_052104 -

Structural Variations from Database of Genomic Variants (DGV) for RNF113B Gene

Variant ID Type Subtype PubMed ID
nsv7246 OTHER Inversion 18451855

Relevant External Links for RNF113B Gene

HapMap Linkage Disequilibrium report
RNF113B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RNF113B Gene

Disorders for RNF113B Gene

(1) University of Copenhagen DISEASES for RNF113B Gene

genes like me logo Genes that share disorders with RNF113B: view

No data available for UniProtKB/Swiss-Prot for RNF113B Gene

Publications for RNF113B Gene

  1. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PMID: 19549727) Markson G. … Sanderson C.M. (Genome Res. 2009) 3
  4. A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PMID: 19690564) van Wijk S.J. … Timmers H.T. (Mol. Syst. Biol. 2009) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for RNF113B Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate RNF113B
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for RNF113B
    • Block miRNA regulation of RNF113B using miScript Target Protectors

    Sources for RNF113B Gene

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