RNF113B Gene
protein-coding GIFtS: 40
GCID: GC13M098828
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ring finger protein 113B(Previous name: zinc finger protein 183-like 1 )
(Previous symbol: ZNF183L1)
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Aliases
for RNF113B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ring Finger Protein 113B1 2 | | Zinc Finger Protein 183-Like 11 2 3 | | RNF1611 2 3 | | ZNF183L11 2 3 | | BA10G5.11 |
Export aliases for RNF113B gene to outside databasesPrevious GC identifers: GC00U921548 GC13M097627 GC13M079425 |
Summaries
for RNF113B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for RNF113B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_009952.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the RNF113B gene promoter:
USF1 USF2 CUTL1 USF-1:USF-2 NRSF form 2 Ik-2 POU2F1 POU2F1a USF-1 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for RNF113B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat RNF113B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q32.2 Ensembl cytogenetic band: 13q32.2 HGNC cytogenetic band: 13q32.2RNF113B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13M098828: view genomic region
(about GC identifiers)
Start:
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98,828,039 bp from pter |
End:
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98,829,521 bp from pter |
Size:
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1,483 bases |
Orientation:
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minus strand |
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Proteins
for RNF113B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: R113B_HUMAN, Q8IZP6 (See
protein sequence)Recommended Name: RING finger protein 113B Size: 322 amino acids; 36259 Da
1 PDB 3D structure from  and Proteopedia  for RNF113B:2CSY (3D)
Secondary accessions: Q8WWF9 Q96QY9Explore the universe of human proteins at neXtProt for RNF113B: NX_Q8IZP6
RNF113B Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_849192.1
ENSEMBL proteins: ENSP00000267291
Human Recombinant Protein Products:
RNF113B Antibody Products:
Assay Products for RNF113B: |
Protein
Domains /
Families
for RNF113B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
RNF113B for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IZP6ProtoNet protein and cluster: Q8IZP6 2 Blocks protein families: IPB000571 Zn-finger IPB001841 Zn-finger
UniProtKB/Swiss-Prot: R113B_HUMAN, Q8IZP6Similarity: Contains 1 C3H1-type zinc fingerSimilarity: Contains 1 RING-type zinc finger |
Function
for RNF113B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for RNF113B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF113B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF113B |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003676 | nucleic acid binding |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- |
RNF113B for ontologies About GeneDecksing
|
Pathways & Interactions
for RNF113B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for RNF113B
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/7 Interacting proteins for RNF113B (Q8IZP63 ENSP000002672914) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
|
Drugs & Compounds
for RNF113B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for RNF113B
Search CenterWatch for drugs/clinical trials and news about RNF113B / R113B
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Transcripts
for RNF113B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for RNF113B gene: NM_178861.4 Unigene Cluster for RNF113B: Ring finger protein 113B Hs.296045 [show with all ESTs]Unigene Representative Sequence: BC0175851 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000267291(uc001vnk.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: RNF113B (NM_178861) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for RNF113B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF113B |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF113B
Browse OriGene validated miRNA SYBR primer pairs
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Additional cDNA sequence: AF539427.1 BC017585.2 BC025388.1 2 DOTS entries: DT.120786864 DT.219833 19 AceView cDNA sequences: BC025388 BI827854 AI204135 AW275115 BC017585 AI935007 AA883163 AW241986 BX116709 AA435942 NM_178861 AF539427 BI459662 BI826627 BG718251 BM554222 BG720695 AI150219 AW183950
GeneLoc Exon Structure
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Expression
for RNF113B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| RNF113B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GATGGATGAA
About this image
See RNF113B Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.296045
SABiosciences Custom PCR Arrays for RNF113B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF113B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat RNF113B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat RNF113B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat RNF113B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF113B |
Orthologs
for RNF113B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for RNF113B gene from 7/22 species (see all 22) About this table
ENSEMBL Gene Tree for RNF113B (if available)
TreeFam Gene Tree for RNF113B (if available) |
Paralogs
for RNF113B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for RNF113B gene
- RNF113A2
2 SIMAP similar genes for RNF113B using alignment to 1 protein entry: R113B_HUMAN:RNF113A SAMD13
RNF113B for paralogs About GeneDecksing
|
Genomic Variants
for RNF113B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing RNF113B |
|
Disorders
/ Diseases
for RNF113B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
RNF113B for disorders About GeneDecksing
2  diseases for RNF113B: About MalaCardskeratoconus malaria
1 disease from the University of Copenhagen DISEASES database for RNF113B:Keratoconus Export disorders for RNF113B gene to outside databases
|
Publications
for RNF113B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for RNF113B gene integrated from 9 sources:
(articles sorted by number of sources associating them with RNF113B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
- Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (2009)
- A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. (PubMed id 19690564)1 van Wijk S.J....Timmers H.T. (2009)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for RNF113B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing RNF113B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing RNF113B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing RNF113B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for RNF113B | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for RNF113B gene:
Search GeneIP for patents involving RNF113B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for RNF113B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for RNF113B | | OriGene shRNA RFP for RNF113B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for RNF113B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for RNF113B | | | OriGene Protein Over-expression Lysate for RNF113B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for RNF113B | | OriGene 3'-UTR Clone for RNF113B | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for RNF113B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for RNF113B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for RNF113B |
|  |  |  | | | | Search ThermoFisher Antibodies for RNF113B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat RNF113B |
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